{"id":14181,"date":"2019-01-04T01:00:00","date_gmt":"2019-01-03T17:00:00","guid":{"rendered":"http:\/\/swarma.org\/c65638712f\/"},"modified":"2019-01-23T10:51:28","modified_gmt":"2019-01-23T02:51:28","slug":"c65638712f","status":"publish","type":"post","link":"https:\/\/swarma.org\/?p=14181","title":{"rendered":"\u5408\u6210\u751f\u7269\u5b66\u5982\u4f55\u7406\u89e3\u548c\u6784\u5efa\u751f\u547d\u590d\u6742\u6027\uff1f| \u9876\u5c16\u79d1\u5b66\u5bb6\u8bbf\u8c08"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-align: center;margin-left: 8px;margin-right: 8px;line-height: 1.75em\"><img class=\"\" style=\"text-align: center;width: 540px;height: 360px\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma10-1546606828.jpeg\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/p>\n<section class=\"mpa-template\">\n<section class=\"\">\n<section><span><strong><span>\u5bfc\u8bed<\/span><\/strong><\/span><\/section>\n<section>\n<section>\n<section>\n<p><span>\u4f5c\u4e3a\u4e00\u4e2a\u8de8\u5b66\u79d1\u7684\u65b0\u5174\u9886\u57df\uff0c<strong>\u5408\u6210\u751f\u7269\u5b66\uff08synthetic biology\uff09<\/strong>\u8bd5\u56fe\u4ece\u5de5\u7a0b\u89d2\u5ea6\u7406\u89e3\u548c\u6784\u5efa\u751f\u547d\u7684\u590d\u6742\u6027\uff0c\u4e5f\u5728\u4e3a\u751f\u7269\u533b\u7597\u3001\u751f\u7269\u6280\u672f\u548c\u57fa\u7840\u5206\u5b50\u7814\u7a76\u6301\u7eed\u6ce8\u5165\u52a8\u529b\u3002<\/span><\/p>\n<p><span><\/span><\/p>\n<p><span>Nature \u6742\u5fd7\u66fe\u57282014\u5e74\u5bf9\u5408\u6210\u751f\u7269\u5b66\u9886\u57df5\u4f4d\u9876\u5c16\u79d1\u5b66\u5bb6\u8fdb\u884c\u8fc7\u4e00\u6b21\u8bbf\u8c08\uff0c\u4ed6\u4eec\u5c31<strong>\u5408\u6210\u751f\u7269\u5b66\u7684\u672a\u6765\uff0c\u5408\u6210\u751f\u7269\u5b66\u5728\u57fa\u7840\u548c\u5e94\u7528\u79d1\u5b66\u7684\u4e3b\u8981\u6210\u5c31\uff0c\u4ee5\u53ca\u5408\u6210\u751f\u7269\u5b66\u5e26\u6765\u7684\u751f\u7269\u4f26\u7406\u95ee\u9898<\/strong>\u5206\u4eab\u4e86\u5404\u81ea\u7684\u89c2\u70b9\u548c\u89c1\u89e3\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"editor\">\n<section>\n<section style=\"padding: 10px\">\n<section>\n<p style=\"text-align: justify;margin-left: 8px;margin-right: 8px;line-height: 1.75em\"><span style=\"font-size: 15px\">2018\u5e74\uff0cCRISPR-Cas9\u6280\u672f\u968f\u7740\u57fa\u56e0\u7f16\u8f91\u5a74\u513f\u4e8b\u4ef6\u53c8\u706b\u4e86\u4e00\u628a\uff0c\u4f46\u8fd9\u9879\u6280\u672f2013\u5e74\u624d\u521a\u521a\u8bde\u751f\uff0c\u5982\u4eca\u5df2\u7ecf\u6210\u4e3a\u4e00\u9879\u6bcf\u4e2a\u5206\u5b50\u5b9e\u9a8c\u5ba4\u5fc5\u5907\u7684\u6280\u672f\uff0c\u540c\u65f6\u65b0\u578b\u7684\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u4e5f\u5728\u4e00\u4e2a\u63a5\u4e00\u4e2a\u7684\u88ab\u5f00\u53d1\u51fa\u6765\u3002\u5728\u8fd9\u51e0\u5e74\u91cc\uff0c\u5408\u6210\u751f\u7269\u5b66\u7684\u8bbe\u8ba1\u80fd\u529b\u4e0d\u65ad\u589e\u52a0\uff0c\u4e0d\u4ec5\u4ec5\u662f\u5728\u590d\u6742\u7684\u57fa\u56e0\u7535\u8def\u65b9\u9762\uff0c\u5728\u57fa\u56e0\u7ec4\u5c42\u9762\uff0c\u6211\u4eec\u4e5f\u6709\u4e86\u957f\u8db3\u7684\u8fdb\u6b65\u548c\u9f13\u821e\u4eba\u5fc3\u7684\u8fdb\u5c55\uff0c\u5982Craig Venter\u7684Synthia 3.0\uff0c\u9175\u6bcd\u57fa\u56e0\u7ec4\u8ba1\u5212Sc2.0\uff0c\u4eba\u7c7b\u57fa\u56e0\u7ec4\u5408\u6210\u8ba1\u5212\u2014HGP Write\uff1b\u5408\u6210\u751f\u7269\u5b66\u7684\u5e94\u7528\u4e5f\u5728\u4e0d\u65ad\u7684\u589e\u52a0\uff0c\u57fa\u56e0\u7f16\u8f91\uff0c\u5929\u7136\u4ea7\u7269\uff0c\u764c\u75c7\u7597\u6cd5\uff0c\u5668\u5b98\u79fb\u690d&#8230;&#8230;<\/span><\/p>\n<\/section>\n<section>\n<p style=\"text-align: justify;margin-left: 8px;margin-right: 8px;line-height: 1.75em\"><span style=\"font-size: 15px\">\u4f46\u662f\u628a\u4e00\u7bc7\u65e7\u95fb\u7ffb\u51fa\u6765\u6709\u4ec0\u4e48\u7528\u5462\uff1f\u9996\u5148\u8fd9\u7bc7\u6587\u7ae0\u4e2d\u7684\u8bbf\u8c08\u4eba\u7269\u662f\u5728\u5408\u6210\u751f\u7269\u5b66\u9886\u57df\u505a\u51fa\u8fc7\u7a81\u51fa\u8d21\u732e\u7684\u9876\u5c16\u79d1\u5b66\u5bb6\u3002\u540c\u65f6\u6211\u8ba4\u4e3a\u5373\u4f7f\u8fc7\u53bb\u4e86\u6570\u5e74\uff0c\u5728\u8fd9\u7bc7\u62a5\u9053\u4e2d5\u4f4d\u79d1\u5b66\u5bb6\u6240\u63d0\u5230\u7684\u5408\u6210\u751f\u7269\u5b66\u6240\u9762\u4e34\u7684\u673a\u9047\u4e0e\u6311\u6218\u4ecd\u7136\u5bf9\u6211\u4eec\u6709\u6307\u5bfc\u610f\u4e49\u3002\u5e0c\u671b\u901a\u8fc7\u8fd9\u7bc7\u6587\u7ae0\u53ef\u4ee5\u8ba9\u5927\u5bb6\u4e86\u89e3\u5230\u8fd9\u4e2a\u9886\u57df\u9876\u5c16\u7684\u79d1\u5b66\u5bb6\u7684\u6b63\u5728\u601d\u8003\u4ec0\u4e48\uff0c\u4e5f\u5e0c\u671b\u5404\u4f4d\u80fd\u591f\u8fdb\u4e00\u6b65\u4e86\u89e3\u5408\u6210\u751f\u7269\u5b66\u3002\uff08\u6587\u672b\u96445\u4f4d\u79d1\u5b66\u5bb6\u7684\u7b80\u8981\u4ecb\u7ecd\uff09<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"editor\">\n<section>\n<section>\n<section>\n<blockquote>\n<p style=\"margin-right: 8px;margin-left: 8px\"><span>Nature \u539f\u9898\uff1a<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px\"><span>Realizing the potential of synthetic biology<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px\"><span>\u539f\u6587\u94fe\u63a5\uff1a<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px\"><span>https:\/\/www.nature.com\/articles\/nrm3767<\/span><\/p>\n<\/blockquote>\n<section class=\"mpa-template\">\n<section style=\"margin-top: 20px\">\n<section style=\"min-width: 200px;min-height: 40px;border-right: 2px solid #e6e6e6;border-bottom: 2px solid #e6e6e6;padding: 0 5px 5px 0\">\n<section>\n<section><\/section>\n<section style=\"color: #4f4f4f;line-height: 30px\">\n<section><strong><span>1 \u5408\u6210\u751f\u7269\u5b66\u7684\u53d1\u5c55\u4e0e\u5b66\u79d1\u4e4b\u95f4\u7684\u5173\u8054<\/span><\/strong><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em\"><span style=\"font-size: 15px\"><strong><span>\u95ee\uff1a<\/span><\/strong><span>\u73b0\u5728\u8d8a\u6765\u8d8a\u591a\u7684\u7684\u51fa\u7248\u7269\u548c\u7814\u7a76\u673a\u6784\u6b63\u5728\u5173\u6ce8\u5408\u6210\u751f\u7269\u5b66\u3002\u4ece\u6700\u521d\u5173\u6ce8\u5408\u6210\u57fa\u56e0\u7535\u8def\u7684\u8bbe\u8ba1\u5f00\u59cb\uff0c\u8be5\u9886\u57df\u662f\u5982\u4f55\u8fdb\u4e00\u6b65\u53d1\u5c55\u7684\uff1f\u4eca\u5929\u6211\u4eec\u6240\u8c08\u7684\u5408\u6210\u751f\u7269\u5b66\u4e0e\u5176\u4ed6\u7684\u5b66\u79d1\u6709\u4ec0\u4e48\u5173\u7cfb\u5462\uff1f\u6bd4\u5982\u7cfb\u7edf\u751f\u7269\u5b66\u548c\u6570\u5b66\u5efa\u6a21\u3002<\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em\"><span style=\"font-size: 15px\"><em><strong><span>Ron<\/span><span><\/span><span>Weiss.<\/span><\/strong><\/em><span>\u7b80\u5355\u5408\u6210\u57fa\u56e0\u7535\u8def\u8bbe\u8ba1\u5982\u53cc\u7a33\u6001\u5f00\u5173\u3001\u9707\u8361\u5668\u548c\u4eba\u9020\u7ec6\u80de\u901a\u8baf\u7cfb\u7edf\u5728\u7ec6\u83cc\u4e2d\u7684\u6210\u529f\u4ee3\u8868\u7740\u5408\u6210\u751f\u7269\u5b66\u7684\u6b63\u5f0f\u521b\u7acb\u3002\u901a\u8fc7\u4f7f\u7528\u975e\u8f6c\u5f55\u8c03\u63a7\u903b\u8f91\u5305\u62ecmicroRNAs\uff0c\u86cb\u767d\u8d28\u78f7\u9178\u5316\u548cDNA\u7f16\u8f91\u6280\u672f\uff0c\u5408\u6210\u751f\u7269\u5b66\u7684\u5173\u6ce8\u70b9\u5df2\u7ecf\u4ece\u5c0f\u578b\u8f6c\u5f55\u8c03\u63a7\u7f51\u7edc\u8f6c\u5411\u4e86\u66f4\u52a0\u590d\u6742\u7684\u591a\u7ec6\u80de\u7cfb\u7edf\u8bf8\u5982\u9175\u6bcd\u3001\u54fa\u4e73\u52a8\u7269\u7ec6\u80de\u548c\u690d\u7269\u3002\u8be6\u7ec6\u3001\u7cbe\u786e\u7684\u523b\u753b\u4e0e\u53ef\u9884\u6d4b\u7684\u5143\u4ef6\u8bbe\u8ba1\u5df2\u7ecf\u6210\u4e3a\u6784\u5efa\u5177\u6709\u590d\u6742\u591a\u4fe1\u53f7\u8f93\u5165\u903b\u8f91\u529f\u80fd\u3001\u590d\u5408\u591a\u6001\u57fa\u56e0\u7535\u8def\u7684\u5173\u952e\u3002\u8fd9\u4f7f\u5f97\u7ec6\u80de\u4f20\u611f\u5668\uff08Sensor\uff09\u548c\u6267\u884c\u5668\uff08Actuator\uff09\u7684\u80fd\u529b\u5f97\u4ee5\u63d0\u9ad8\uff0c\u591a\u6837\u6027\u4e5f\u6709\u6240\u589e\u52a0\u3002<\/span><\/span><\/p>\n<p style=\"line-height: 1.75em;margin-left: 8px;margin-right: 8px\"><span><\/span><\/p>\n<p style=\"text-align: center;margin-left: 8px;margin-right: 8px;line-height: 1.75em\"><img class=\"\" style=\"width: 540px;height: 304px\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma9-1546606828.jpeg\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/p>\n<p style=\"text-align: center;line-height: normal;margin-left: 8px;margin-right: 8px\"><strong><span>\u53cc\u7a33\u6001\u5f00\u5173\uff08Genetic Toggle Switch\uff09<\/span><\/strong><\/p>\n<p style=\"text-align: center;line-height: normal;margin-left: 8px;margin-right: 8px\"><strong><span>\u9707\u8361\u5668\uff08Genetic Repressilator\uff09\u4e0e<\/span><\/strong><\/p>\n<p style=\"text-align: center;line-height: normal;margin-left: 8px;margin-right: 8px\"><strong><span>\u4eba\u9020\u7ec6\u80de\u901a\u8baf\u7cfb\u7edf\uff08Cell-cell Communication Circuits\uff09<\/span><\/strong><\/p>\n<p><span style=\"font-size: 15px\">\u6211\u8ba4\u4e3a\uff0c\u5408\u6210\u751f\u7269\u5b66\u548c\u7cfb\u7edf\u751f\u7269\u5b66\u662f\u4e00\u79cd\u4e92\u8865\u7684\u5173\u7cfb\uff1a\u524d\u8005\u57fa\u4e8e\u6b63\u5411\u5de5\u7a0b\u5b66\uff0c\u800c\u540e\u8005\u57fa\u4e8e\u53cd\u5411\u5de5\u7a0b\u5b66\u3002\u7cfb\u7edf\u751f\u7269\u5b66\u5bf9\u81ea\u7136\u8fc7\u7a0b\u7684\u7814\u7a76\u6210\u679c\u53ef\u4ee5\u63d0\u9ad8\u5408\u6210\u751f\u7269\u5b66\u5bf9\u751f\u7269\u7cfb\u7edf\u7684\u8bbe\u8ba1\u80fd\u529b\uff0c\u540c\u65f6\u5408\u6210\u751f\u7269\u5b66\u521b\u5efa\u7684\u5c0f\u578b\u4eba\u5de5\u7f51\u7edc\u6709\u52a9\u4e8e\u68c0\u9a8c\u7cfb\u7edf\u751f\u7269\u5b66\u5bf9\u81ea\u7136\u7cfb\u7edf\u63d0\u51fa\u7684\u5047\u8bbe\u3002\u8ba1\u7b97\u673a\u5efa\u6a21\u5de5\u5177\u5219\u6210\u4e3a\u4eba\u5de5\u8c03\u63a7\u7f51\u7edc\u8bbe\u8ba1\u4e2d\u7684\u5fc5\u8981\u6761\u4ef6\uff0c\u540c\u65f6\u5b83\u4e5f\u5728\u591a\u79cd\u751f\u7269\u5b66\u9886\u57df\u53d1\u6325\u7740\u91cd\u8981\u7684\u4f5c\u7528\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u6700\u540e\uff0c\u5408\u6210\u751f\u7269\u5b66\u7814\u7a76\u4eba\u5458\u5bf9\u751f\u7269\u7cfb\u7edf\u590d\u6742\u6027\u7684\u8ba4\u8bc6\u4e5f\u5728\u9010\u6e10\u63d0\u9ad8\u3002\u751f\u7269\u672c\u8eab\u7684\u590d\u6742\u6027\u8ba9\u6211\u4eec\u8ba4\u8bc6\u5230\u6211\u4eec\u9700\u8981\u8de8\u5b66\u79d1\u4ea4\u53c9\u6027\u7814\u7a76\u3001\u65b0\u7684\u57fa\u56e0\u7535\u8def\u8bbe\u8ba1\u539f\u7406\u4ee5\u53ca\u7a0b\u5e8f\u8bbe\u8ba1\u8303\u5f0f\u6765\u514b\u670d\u5408\u6210\u751f\u7269\u5b66\u6240\u9047\u5230\u7684\u95ee\u9898\u548c\u74f6\u9888\uff0c\u4f8b\u5982\u4ee3\u8c22\u8d1f\u8377\uff08metabolic load\uff09\uff0c\u5e72\u6270\uff08crosstalk\uff09\uff0c\u8d44\u6e90\u5206\u914d\uff08resource sharing\uff09\u548c\u57fa\u56e0\u8868\u8fbe\u566a\u58f0\uff08gene expression noise\uff09\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>George M. Church.<\/em><\/span><\/strong><span style=\"font-size: 15px;font-weight: 600\"><em><\/em><\/span>\u5728\u6211\u7684\u89c2\u70b9\u4e2d\uff0c\u5408\u6210\u751f\u7269\u5b66\u4ece\u6765\u6ca1\u6709\u5b8c\u5168\u4e13\u6ce8\u5728\u9057\u4f20\u7535\u8def\u8bbe\u8ba1\u4e0a\uff0c\u800c\u662f\u4e13\u6ce8\u5728\u8ba9\u751f\u7269\u5feb\u901f\u6210\u719f\u4e3a\u5de5\u7a0b\u5b66\u79d1\u7684\u9886\u57df\uff0c\u5305\u62ec\u8ba1\u7b97\u673a\u8f85\u52a9\u8bbe\u8ba1\uff0c\u5b89\u5168\u7cfb\u7edf\u6784\u5efa\uff0c\u6574\u5408\u6a21\u578b\uff0c\u57fa\u56e0\u7ec4\u7f16\u8f91\u548c\u751f\u7269\u8fdb\u5316\u3002\u5408\u6210\u751f\u7269\u5b66\u4e0d\u5b8c\u5168\u50cf\u9ad8\u5ea6\u6a21\u5757\u5316\uff08\u6216\u201c\u5f00\u5173\u5f0f\u201d\uff09\u7684\u7535\u6c14\u5de5\u7a0b\u548c\u8ba1\u7b97\u673a\u79d1\u5b66\uff0c\u5176\u66f4\u50cf\u662f\u571f\u6728\u5de5\u7a0b\u548c\u673a\u68b0\u5de5\u7a0b\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;margin-left: 8px;margin-right: 8px;text-align: center\"><img class=\"\" style=\"width: 544px;height: 306px\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma9-1546606829.jpeg\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/p>\n<p style=\"text-align: center;line-height: 1.75em;margin-left: 8px;margin-right: 8px\"><span style=\"font-size: 13px\"><strong><span>\u8ba1\u7b97\u673a\u8f85\u52a9\u8bbe\u8ba1 Computer-Aided-Design<\/span><\/strong><\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><span><em>Michael B. Elowitz.<\/em><\/span><\/strong>\u901a\u5e38\u6765\u8bf4\uff0c\u5408\u6210\u751f\u7269\u5b66\u5c06\u751f\u7269\u5b66\u4ece\u73b0\u6709\u7269\u79cd\u548c\u7ec6\u80de\u7cfb\u7edf\u7684\u7a7a\u95f4\u6269\u5c55\u5230\u66f4\u5927\u7684\u975e\u81ea\u7136\u4f46\u53ef\u884c\u7684\u7269\u79cd\u548c\u7cfb\u7edf\u7a7a\u95f4\u3002\u867d\u7136\u4e00\u5f00\u59cb\u6211\u4eec\u901a\u8fc7\u57fa\u56e0\u7535\u8def\u6765\u5b9e\u73b0\u4e00\u4e9b\u6700\u7b80\u5355\u7684\u52a8\u6001\u884c\u4e3a\uff0c\u4f46\u662f\u76ee\u524d\u5408\u6210\u751f\u7269\u5b66\u7814\u7a76\u65b9\u6cd5\u5df2\u5e7f\u6cdb\u7684\u5e94\u7528\u5230\u4ece\u4ee3\u8c22\u5230\u591a\u7ec6\u80de\u53d1\u80b2\u7b49\u5404\u79cd\u5404\u6837\u7684\u751f\u7269\u9886\u57df\u4e2d\u3002\u5408\u6210\u751f\u7269\u5b66\u4f7f\u5f97\u6211\u4eec\u80fd\u591f\u6e05\u695a\u7684\u77e5\u6653\u4f55\u79cd\u7c7b\u578b\u7684\u57fa\u56e0\u7535\u8def\u8bbe\u8ba1\u80fd\u591f\u5b9e\u73b0\u4f55\u79cd\u7684\u7ec6\u80de\u884c\u4e3a\u3002\u901a\u8fc7\u5728\u6d3b\u7ec6\u80de\u4e2d\u6784\u5efa\u548c\u6d4b\u8bd5\u8fd9\u4e9b\u57fa\u56e0\u7535\u8def\uff0c\u6211\u4eec\u4e5f\u9010\u6e10\u660e\u767d\u4e86\u4e0d\u540c\u8bbe\u8ba1\u4e4b\u95f4\u7684\u4f18\u52a3\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u8fd9\u6837\u4e00\u6765\uff0c\u9664\u4e86\u4f20\u7edf\u7684\u53cd\u5411\u5de5\u7a0b\u5b66\u7684\u624b\u6bb5\uff0c\u6211\u4eec\u8fd8\u53ef\u4ee5\u5229\u7528\u6b63\u5411\u5de5\u7a0b\u5b66\u7684\u65b9\u6cd5\u6765\u5b9e\u73b0\u201cBuilding to Understand It\u201d\u3002\u9664\u4e86\u8bb8\u591a\u91cd\u8981\u7684\u76f4\u63a5\u5e94\u7528\u4e4b\u5916\uff0c\u6211\u8ba4\u4e3a\u6b63\u662f\u5bf9\u4e8e\u751f\u7269\u7cfb\u7edf\u601d\u8003\u548c\u7814\u7a76\u65b9\u5f0f\u7684\u8f6c\u53d8\uff0c\u5927\u5927\u7684\u6fc0\u53d1\u4e86\u66f4\u591a\u4eba\u7684\u60f3\u8c61\u529b\uff0c\u8fdb\u800c\u4fc3\u8fdb\u4e86\u5408\u6210\u751f\u7269\u5b66\u9886\u57df\u7684\u5feb\u901f\u53d1\u5c55\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;text-align: center;margin-left: 8px;margin-right: 8px\"><img class=\"\" style=\"width: 540px;height: 443px\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma4-1546606829.jpeg\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/p>\n<p><span style=\"font-size: 15px\">\u5904\u4e8e\u5408\u6210\u751f\u7269\u5b66\u6838\u5fc3\u7684\u57fa\u7840\u6027\u95ee\u9898\u5f88\u5927\u7a0b\u5ea6\u4e0a\u4e0e\u7cfb\u7edf\u751f\u7269\u5b66\u662f\u76f8\u4e92\u91cd\u53e0\u7684\uff0c\u56e0\u4e3a\u4e24\u4e2a\u9886\u57df\u90fd\u5728\u81f4\u529b\u4e8e\u7406\u89e3\u57fa\u56e0\u7535\u8def\u7684\u8bbe\u8ba1\u539f\u7406 \u3002\u800c\u4e14\u6211\u9884\u8ba1\u8fd9\u4e9b\u9886\u57df\u5c06\u4f1a\u76f8\u4e92\u4ea4\u53c9\u5f71\u54cd\uff0c\u5e76\u8d8a\u6765\u8d8a\u96be\u4ee5\u5728\u672a\u6765\u5206\u522b\u5f00\u6765\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>Christina D. Smolke<\/em><\/span><\/strong><span style=\"font-size: 15px;font-weight: 600\"><em><\/em>.<\/span>\u5408\u6210\u751f\u7269\u5b66\u548c\u7cfb\u7edf\u751f\u7269\u5b66\u90fd\u4e0e\u5176\u53d1\u5c55\u800c\u6765\u7684\u9886\u57df\u5728\u65b9\u6cd5\u4e0a\u90fd\u53d1\u751f\u4e86\u6839\u672c\u6027\u8f6c\u53d8\u3002\u76f8\u6bd4\u4e8e\u4f20\u7edf\u7684\u57fa\u56e0\u5de5\u7a0b\u7814\u7a76\uff0c\u5408\u6210\u751f\u7269\u5b66\u5728\u8bbe\u8ba1\u3001\u6784\u9020\u548c\u523b\u753b\u751f\u7269\u7cfb\u7edf\u65b9\u9762\u66f4\u52a0\u5f3a\u8c03\u5de5\u7a0b\u5b66\u539f\u7406\u548c\u65b9\u6cd5\u5b66\u3002\u800c\u76f8\u5bf9\u4e8e\u5728\u4f20\u7edf\u751f\u7269\u7814\u7a76\u4e2d\u7684\u8fd8\u539f\u8bba\u65b9\u6cd5\uff0c\u7cfb\u7edf\u751f\u7269\u5b66\u5219\u662f\u5728\u7814\u7a76\u6574\u4f53\u7cfb\u7edf\u7ec4\u6210\u7684\u65b9\u9762\u53d1\u751f\u4e86\u6839\u672c\u6027\u8f6c\u53d8\u3002\u8ba1\u7b97\u673a\u5efa\u6a21\u5728\u4e24\u4e2a\u9886\u57df\u90fd\u662f\u91cd\u8981\u7684\u5de5\u5177\uff0c\u4f46\u662f\u5728\u4e24\u4e2a\u9886\u57df\u7684\u5e94\u7528\u6709\u6240\u4e0d\u540c\u3002\u5728\u7cfb\u7edf\u751f\u7269\u5b66\u4e2d\uff0c\u8ba1\u7b97\u6a21\u578b\u7528\u4e8e\u9884\u6d4b\u7cfb\u7edf\u7684\u884c\u4e3a\uff0c\u800c\u5728\u5408\u6210\u751f\u7269\u5b66\u4e2d\uff0c\u5efa\u6a21\u5219\u7528\u4e8e\u6307\u5bfc\u4eba\u5de5\u7cfb\u7edf\u7684\u8bbe\u8ba1\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u5408\u6210\u751f\u7269\u5b66\u5df2\u7ecf\u4ece\u6700\u521d\u7684\u76f8\u5f53\u72ed\u7a84\u7684\u5173\u6ce8\u70b9\u4e2d\u5927\u5927\u6269\u5c55\u5f00\u6765\u3002\u7814\u7a76\u4eba\u5458\u66f4\u52a0\u5145\u5206\u5730\u8ba4\u8bc6\u5230\u4e86\u5929\u7136\u751f\u7269\u7cfb\u7edf\u4e2d\u673a\u5236\u7684\u591a\u6837\u6027\uff0c\u540c\u65f6\u4e5f\u5728\u5145\u5206\u5229\u7528\u7740\u5929\u7136\u7cfb\u7edf\u7684\u591a\u6837\u6027\u3002\u4f8b\u5982\uff0c\u7edd\u5927\u591a\u6570\u65e9\u671f\u7684\u5de5\u4f5c\u96c6\u4e2d\u5728\u57fa\u4e8e\u8f6c\u5f55\u56e0\u5b50\u7684\u8c03\u63a7\u7f51\u7edc\u8bbe\u8ba1\u4e0a\uff0c\u4ee5\u5c55\u73b0\u4eba\u5de5\u7cfb\u7edf\u7684\u52a8\u6001\u884c\u4e3a\uff08\u50cf\u9707\u8361\u5b50\u548c\u53cc\u7a33\u6001\u5f00\u5173\uff09\uff0c\u7136\u800c\u73b0\u5728\u7684\u8bbe\u8ba1\u4e00\u822c\u90fd\u4f1a\u5305\u542b\u5176\u5b83\u5c42\u6b21\u7684\u8c03\u63a7\u8bbe\u8ba1\uff0c\u5305\u62ec\u57fa\u4e8eRNA\u7684\u8c03\u63a7\u5b50\uff0c\u7ffb\u8bd1\u540e\u8c03\u63a7\u4fee\u9970\u548c\u5206\u5b50\u652f\u67b6\u7b49\u7b49\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u53e6\u4e00\u4e2a\u4f8b\u5b50\uff0c\u7a81\u53d8\u548c\u8fdb\u5316\u4e4b\u524d\u88ab\u5e7f\u6cdb\u8ba4\u4e3a\u662f\u7cfb\u7edf\u6027\u80fd\u7684\u4e00\u4e2a\u963b\u788d\uff0c\u9700\u8981\u5c06\u5176\u5f71\u54cd\u964d\u5230\u6700\u4f4e\u3002\u7136\u800c\u76ee\u524d\u6700\u65b0\u7684\u7814\u7a76\u6b63\u5728\u63a2\u7d22\u751f\u7269\u7cfb\u7edf\u8fd9\u4e2a\u72ec\u7279\u7684\u6027\u8d28\uff0c\u5229\u7528\u751f\u7269\u7684\u8fdb\u5316\u548c\u9002\u5e94\u6027\u8d28\u8fdb\u884c\u8bbe\u8ba1\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;margin-left: 8px;margin-right: 8px;text-align: center\"><img class=\"\" style=\"width: 540px;height: 395px\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma6-1546606829.jpeg\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/p>\n<p style=\"text-align: center;line-height: 1.75em;margin-left: 8px;margin-right: 8px\"><strong><span>\u5408\u6210\u751f\u7269\u5b66\u57fa\u56e0\u7ebf\u8def\u6216\u8005\u88c5\u7f6e\u7684\u8bbe\u8ba1\u539f\u5219<\/span><\/strong><\/p>\n<p><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>Christopher A. Voigt<\/em><\/span><\/strong><em>.<\/em>\u8fd9\u4e2a\u9886\u57df\u65e9\u671f\u7684\u4e00\u4e9b\u76ee\u6807\u90fd\u56f4\u7ed5\u5728\u521b\u9020\u53ef\u6267\u884c\u4e00\u7cfb\u5217\u7a0b\u5e8f\u5316\u4efb\u52a1\u7684\u7ec6\u80de\u5c55\u5f00\u3002\u4f8b\u5982\uff0cAdam Arkin\u8bbe\u60f3\u4e86\u4e00\u79cd\u53ef\u4ee5\u5728\u4eba\u4f53\u5185\u8bc6\u522b\u5fae\u73af\u5883\u5e76\u6267\u884c\u6cbb\u7597\u529f\u80fd\u7684\u5de5\u7a0b\u83cc\u3002\u60f3\u8981\u505a\u5230\u8fd9\u4e00\u70b9\uff0c\u9700\u8981\u63a7\u5236\u76f8\u5173\u7684\u57fa\u56e0\u5728\u7279\u5b9a\u65f6\u95f4\u7279\u5b9a\u73af\u5883\u72b6\u6001\u4e0b\u5f00\u542f\uff0c\u8fd9\u9700\u8981\u5408\u6210\u751f\u7269\u5b66\u7684\u8c03\u63a7\u65b9\u5f0f\uff0c\u4e5f\u5c31\u662f\u8bf4\uff0c\u901a\u8fc7\u57fa\u56e0\u7535\u8def\u6765\u8c03\u63a7\u3002\u8fd9\u4e5f\u4e00\u76f4\u662f\u4f20\u7edf\u57fa\u56e0\u5de5\u7a0b\u9886\u57df\u96be\u4ee5\u89e3\u51b3\u7684\u95ee\u9898\u4e4b\u4e00\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u5408\u6210\u751f\u7269\u5b66\u662f\u4e00\u4e2a\u5de5\u7a0b\u5b66\u79d1\uff0c\u5728\u8fd9\u4e2a\u9886\u57df\u7814\u7a76\u4eba\u5458\u6e34\u671b\u53bb\u521b\u9020\u4e00\u4e9b\u81ea\u7136\u754c\u4e2d\u4e0d\u5b58\u5728\u7684\u4e1c\u897f\u3002\u800c\u7cfb\u7edf\u751f\u7269\u5b66\u662f\u4e00\u4e2a\u57fa\u7840\u5b66\u79d1\uff0c\u5b83\u7684\u76ee\u6807\u662f\u66f4\u597d\u7684\u7406\u89e3\u81ea\u7136\u7684\u751f\u7269\u5b66\u3002\u8fd9\u79cd\u5173\u7cfb\u7c7b\u4f3c\u4e8e\u751f\u7269\u5de5\u7a0b\u548c\u751f\u7269\u5b66\uff0c\u6216\u5316\u5b66\u5de5\u7a0b\u548c\u5316\u5b66\u3002\u5b66\u79d1\u4e4b\u95f4\u7684\u201c\u8bed\u8a00\u201d\u53ef\u80fd\u662f\u7c7b\u4f3c\u7684\uff0c\u4f46\u662f\u5f7c\u6b64\u7684\u52a8\u673a\u5374\u662f\u4e0d\u540c\u7684\u3002\u4f8b\u5982\uff0c\u5408\u6210\u751f\u7269\u5b66\u548c\u7cfb\u7edf\u751f\u7269\u5b66\u90fd\u5bf9\u6a21\u5757\u5316\u975e\u5e38\u611f\u5174\u8da3\u3002\u5bf9\u4e8e\u81ea\u7136\u7684\u7ec6\u80de\uff0c\u57fa\u56e0\u548c\u8c03\u63a7\u7f51\u7edc\u53ef\u80fd\u662f\u6a21\u5757\u5316\u7684\uff0c\u4e5f\u6709\u53ef\u80fd\u4e0d\u662f\u6a21\u5757\u5316\u7684\uff0c\u8fd9\u53d6\u51b3\u4e8e\u4f60\u5982\u4f55\u5b9a\u6027\u8fd9\u4e2a\u95ee\u9898\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u5de5\u7a0b\u5e08\u5219\u66f4\u52a0\u70ed\u8877\u4e8e\u521b\u9020\u5177\u6709\u66f4\u9ad8\u6a21\u5757\u5316\u7a0b\u5ea6\u7684\u5408\u6210\u57fa\u56e0\u7535\u8def\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u6570\u5b66\u6a21\u578b\u662f\u4e00\u79cd\u5de5\u5177\uff0c\u5b83\u80fd\u591f\u8fdb\u884c\u5b9a\u91cf\u7684\u9884\u6d4b\u6216\u8005\u5bf9\u6570\u636e\u8fdb\u884c\u8be0\u91ca\u3002\u6570\u5b66\u5efa\u6a21\u5bf9\u4e24\u4e2a\u9886\u57df\u90fd\u975e\u5e38\u6709\u7528\uff0c\u5c31\u50cf\u5176\u4ed6\u7684\u5de5\u5177\u5982\u6d4b\u5b9a\u86cb\u767d\u6c34\u5e73\u7684\u8d28\u8c31\u6216\u8005\u5c06DNA\u5bfc\u5165\u7684\u7ec6\u80de\u7684\u8f6c\u5316\u65b9\u6cd5\u4e00\u6837\u5728\u5f88\u591a\u9886\u57df\u90fd\u6709\u5e94\u7528\u3002<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;text-align: center;line-height: normal\"><img class=\"\" style=\"width: 540px;height: 563px\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma1-1546606830.jpeg\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/p>\n<p style=\"text-align: center;margin-left: 8px;margin-right: 8px;line-height: normal\"><strong><span>\u7cfb\u7edf\u751f\u7269\u5b66 &amp; \u5408\u6210\u751f\u7269\u5b66\u9762\u4e34\u7684\u6311\u6218\u548c\u534f\u540c\u5173\u7cfb<\/span><\/strong><\/p>\n<\/p>\n<section class=\"editor\">\n<section>\n<section>\n<section class=\"mpa-template\">\n<section style=\"margin-top: 20px\">\n<section style=\"min-width: 200px;min-height: 40px;border-right: 2px solid #e6e6e6;border-bottom: 2px solid #e6e6e6;padding: 0 5px 5px 0\">\n<section>\n<section><\/section>\n<section style=\"color: #4f4f4f;line-height: 30px\">\n<section><strong><span>2 \u5408\u6210\u751f\u7269\u5b66\u7684\u6210\u5c31\u4e0e\u6311\u6218<\/span><\/strong><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em\"><strong><span>\u95ee\uff1a<\/span><\/strong><span>\u5728\u57fa\u7840\u7814\u7a76\u4e2d\u76ee\u524d\u5408\u6210\u751f\u7269\u5b66\u7684\u4e3b\u8981\u6210\u5c31\u6709\u54ea\u4e9b\uff1f\u8fd9\u4e2a\u9886\u57df\u6b63\u5728\u9762\u4e34\u8fd9\u54ea\u4e9b\u6311\u6218\uff1f<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em\"><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>R.W.<\/em><\/span><\/strong>\u5728\u8fc7\u53bb\u7684\u5341\u5e74\u91cc\uff0c\u5408\u6210\u751f\u7269\u5df2\u7ecf\u5e2e\u52a9\u751f\u7269\u79d1\u5b66\u8f6c\u53d8\u4e3a\u4e00\u95e8\u771f\u6b63\u7684\u5de5\u7a0b\u5b66\u79d1\u3002\u663e\u8457\u7684\u6210\u5c31\u5305\u62ec\u521b\u9020\u4e86\u53ef\u7ec4\u5408\u7684\u57fa\u56e0\u5143\u4ef6\u5e93\uff0c\u5177\u6709\u9769\u547d\u6027\u8fdb\u5c55\u7684\u57fa\u56e0\u5408\u6210\u6280\u672f\u548c\u66f4\u5feb\u66f4\u9ad8\u6548\u7684\u6a21\u5757\u5316DNA\u7ec4\u88c5\u65b9\u6cd5\u3002\u901a\u8fc7\u5c06\u5feb\u901f\u53d1\u5c55\u7684\u751f\u7269\u6280\u672f\u548c\u8ba1\u7b97\u673a\u5efa\u6a21\u7ed3\u5408\u8d77\u6765\uff0c\u5408\u6210\u751f\u7269\u5b66\u5bb6\u73b0\u5728\u53ef\u4ee5\u4ee5\u4e00\u79cd\u53ef\u9884\u6d4b\u7684\u65b9\u5f0f\uff08\u81f3\u5c11\u5728\u4e00\u5b9a\u7a0b\u5ea6\u4e0a\u53ef\u4ee5\u8fd9\u4e48\u8bb2\uff09\u81ea\u4e0a\u800c\u4e0b\u5bf9\u751f\u7269\u7cfb\u7edf\u8fdb\u884c\u8bbe\u8ba1\u548c\u5de5\u7a0b\u5316\u6539\u9020\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u7136\u800c\uff0c\u5408\u6210\u751f\u7269\u5b66\u771f\u6b63\u7f3a\u5c11\u7684\uff0c\u5c31\u6211\u7684\u5b9e\u9a8c\u5ba4\u76ee\u524d\u6b63\u5728\u5173\u6ce8\u7684\u54fa\u4e73\u52a8\u7269\u5408\u6210\u751f\u7269\u5b66\u6765\u8bf4\uff0c\u662f\u73b0\u5b9e\u4e16\u754c\u4e2d\u7684\u5b9e\u9645\u5e94\u7528\u3002\u6211\u4eec\u5fc5\u987b\u505a\u51fa\u52aa\u529b\u5c06\u5408\u6210\u751f\u7269\u5b66\u7814\u7a76\u4ece\u201c\u73a9\u5f04\u73a9\u5177\u201d\u8f6c\u53d8\u6210\u8ba9\u6574\u4e2a\u793e\u4f1a\u80fd\u591f\u4ece\u4e2d\u53d7\u76ca\u7684\u5b9e\u9645\u5e94\u7528\uff0c\u6bd4\u5982\u764c\u75c7\u6cbb\u7597\uff0c\u75c5\u6bd2\u75ab\u82d7\u548c\u6539\u9020\u7684\u751f\u7269\u7ec4\u7ec7\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u73b0\u5728\u4e3b\u8981\u7684\u6311\u6218\u662f\u5982\u4f55\u5c06\u5408\u6210\u7684\u57fa\u56e0\u7535\u8def\u5b89\u5168\u7684\u9012\u9001\u5230\u54fa\u4e73\u52a8\u7269\u4f53\u5185\u3002\u6211\u8ba4\u4e3a\u57fa\u4e8eRNA\u7684\u9012\u9001\u65b9\u6cd5\u7684\u53d1\u5c55\u5c06\u4f1a\u6539\u53d8\u6e38\u620f\u89c4\u5219\uff1a\u5b83\u5c06\u4f1a\u514b\u670d\u653f\u5e9c\u76d1\u7ba1\u7684\u9650\u5236\uff0c\u540c\u65f6\u6ee1\u8db3\u4f20\u7edf\u57fa\u56e0\u7597\u6cd5\u6240\u8981\u6c42\u7684\u5b89\u5168\u4fdd\u969c\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>G.M.C.<\/em><\/span><\/strong>\u9664\u4e86\u4e00\u4e9b\u5e94\u7528\uff0c\u5408\u6210\u751f\u7269\u5b66\u7684\u6210\u679c\u5305\u62ec\u6307\u6570\u7a0b\u5ea6\u53d1\u5c55\u7684\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u6280\u672f\uff0c\u82af\u7247\u5408\u6210DNA\u6587\u5e93\u6280\u672f\uff0c\u591a\u91cd\u81ea\u52a8\u5316\u57fa\u56e0\u7ec4\u5de5\u7a0b\u6280\u672f\uff08Multiplex automated genome engineering, MAGE\uff09\uff08\u4e3b\u8981\u5728\u5927\u80a0\u6746\u83cc\u4e2d\uff09\u548c\u51e0\u4e4e\u80fd\u5728\u4efb\u4f55\u57fa\u56e0\u7ec4\u4e2d\u8fdb\u884c\u7f16\u8f91\u7684CRISPR-Cas9\u6280\u672f\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;margin-left: 8px;margin-right: 8px;text-align: center\"><img class=\"\" style=\"width: 540px;height: 304px\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma0-1546606830.jpeg\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/p>\n<p style=\"text-align: center;margin-left: 8px;margin-right: 8px;line-height: 1.75em\"><strong><span>\u591a\u91cd\u81ea\u52a8\u5316\u57fa\u56e0\u7ec4\u5de5\u7a0b\u6280\u672f\uff08Multiplex automated genome engineering, MAGE\uff09<\/span><\/strong><\/p>\n<p><span style=\"font-size: 15px\">\u968f\u7740\u57fa\u56e0\u7ec4\u201c\u8bfb\u201d\u4e0e\u201c\u5199\u201d\u6280\u672f\u7684\u4e0d\u65ad\u8fdb\u6b65\uff0c\u65b0\u7684\u6311\u6218\u5728\u4e8e\u65b0\u529f\u80fd\u7684\u7cfb\u7edf\u8bbe\u8ba1\u548c\u7b5b\u9009\uff0c\u4ee5\u53ca\u9ad8\u6548\u7684\u590d\u5236\u548c\u751f\u4ea7\u80fd\u529b\u3002\u6b64\u5916\u7684\u6311\u6218\u8fd8\u5305\u62ec\u5982\u4f55\u9884\u6d4b\uff0c\u6a21\u62df\u548c\u6539\u8fdb\u9ad8\u5ea6\u591a\u6837\u5316\u6216\u4e2a\u6027\u5316\u7684\u6280\u672f\u53ca\u63a2\u7d22\u5176\u5bf9\u590d\u6742\u7684\u751f\u7406\u548c\u751f\u6001\u7cfb\u7edf\u7684\u5f71\u54cd\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><em><span style=\"font-size: 15px\">M.B.E.<\/span><\/em><\/strong>\u6211\u4eec\u5728\u8fd9\u4e2a\u9886\u57df\u5df2\u7ecf\u8d70\u8fc7\u5f88\u957f\u7684\u4e00\u6bb5\u8def\u4e86\uff1a\u6211\u4eec\u5df2\u7ecf\u6784\u5efa\u597d\u51e0\u4ee3\u7248\u672c\u7684\u9707\u8361\u5b50\u548c\u57fa\u56e0\u5f00\u5173\u3002\u5b83\u4eec\u5177\u6709\u591a\u6837\u7684\u7ec6\u80de\u6210\u5206\u548c\u8c03\u8282\u673a\u5236\uff0c\u5e76\u4e14\u80fd\u591f\u548c\u5185\u6e90\u7684\u57fa\u56e0\u7535\u8def\u76f8\u4e92\u4f5c\u7528\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u590d\u6742\u7684\u4ee3\u8c22\u901a\u8def\u88ab\u6539\u9020\u7528\u6765\u751f\u4ea7\u6709\u7528\u7684\u4ea7\u54c1\uff0c\u4fe1\u53f7\u901a\u8def\u4ee5\u53ef\u9884\u6d4b\u7684\u65b9\u5f0f\u88ab\u91cd\u65b0\u8bbe\u8ba1\u6539\u53d8\u5176\u52a8\u6001\u884c\u4e3a\u3002\u7136\u800c\uff0c\u7531\u4e8e\u6280\u672f\u7684\u6311\u6218\u548c\u6211\u4eec\u5bf9\u4e8e\u751f\u7269\u57fa\u56e0\u7535\u8def\u8bbe\u8ba1\u7406\u89e3\u7684\u4e0d\u8db3\uff0c\u5408\u6210\u751f\u7269\u5b66\u4ecd\u7136\u5904\u4e8e\u6781\u5176\u539f\u59cb\u7684\u72b6\u6001\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u5728\u6280\u672f\u65b9\u9762\uff0c\u5408\u6210\u57fa\u56e0\u7535\u8def\u5e76\u5c06\u5b83\u4eec\u5bfc\u5165\u5230\u7ec6\u80de\u5185\u7684\u8fc7\u7a0b\u4ecd\u7136\u5341\u5206\u7f13\u6162\u5e76\u4e14\u95ee\u9898\u9887\u591a\uff0c\u5c24\u5176\u662f\u5728\u54fa\u4e73\u7ec6\u80de\u4e2d\uff0c\u7136\u800c\uff0c\u4e00\u4e9b\u65b0\u7684\u6280\u672f\uff0c\u4f8b\u5982\u57fa\u4e8eCRISPR\u7684\u57fa\u56e0\u7f16\u8f91\u7cfb\u7edf\uff0c\u662f\u6781\u5176\u9f13\u821e\u4eba\u5fc3\u7684\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;margin-left: 8px;margin-right: 8px;text-align: center\"><img class=\"\" style=\"width: 544px;height: 306px\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma6-1546606830.jpeg\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/p>\n<p style=\"text-align: center;margin-left: 8px;margin-right: 8px;line-height: 1.75em\"><strong><span>CRISPR\/cas9\u57fa\u56e0\u7f16\u8f91\u7cfb\u7edf<\/span><\/strong><\/p>\n<p><span style=\"font-size: 15px\">\u5728\u57fa\u7840\u7814\u7a76\u65b9\u9762\uff0c\u6211\u4eec\u5bf9\u57fa\u56e0\u7535\u8def\u5982\u4f55\u5728\u7ec6\u80de\u548c\u7ec4\u7ec7\u4e2d\u6709\u6548\u7684\u53d1\u6325\u4f5c\u7528\u6240\u77e5\u751a\u5c11\uff0c\u6211\u4eec\u4ecd\u7136\u9700\u8981\u4ece\u81ea\u7136\u754c\u4e86\u89e3\u66f4\u591a\u3002\u5177\u4f53\u800c\u8a00\uff0c\u6700\u5927\u7684\u6311\u6218\u4e4b\u4e00\u5c31\u662f\u5c06\u5408\u6210\u751f\u7269\u5b66\u5728\u5355\u4e2a\u5fae\u751f\u7269\u4e2d\u4f5c\u7528\u7684\u57fa\u56e0\u7535\u8def\u8f6c\u79fb\u5230\u591a\u7ec6\u80de\u7cfb\u7edf\u4e2d\u3002\u4f8b\u5982\uff0c\u80fd\u591f\u5b9e\u73b0\u7ec6\u80de\u81ea\u6211\u6a21\u5f0f\u5316\u7684\u57fa\u56e0\u7535\u8def\u3002\u5982\u679c\u80fd\u591f\u6210\u529f\u7684\u8bdd\uff0c\u6211\u4eec\u5c31\u53ef\u80fd\u4ece\u4e00\u4e2a\u5168\u65b0\u7684\u89d2\u5ea6\u7406\u89e3\u591a\u7ec6\u80de\u751f\u7269\u7684\u53d1\u80b2\u8fc7\u7a0b\uff0c\u8fd9\u53ef\u4ee5\u4e3a\u7ec4\u7ec7\u6539\u9020\u548c\u518d\u751f\u63d0\u4f9b\u6709\u7528\u7684\u4fe1\u606f\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>C.D.S.<\/em><\/span><\/strong>\u5408\u6210\u751f\u7269\u5b66\u5bf9\u4e8e\u57fa\u7840\u7814\u7a76\u91cd\u8981\u7684\u5f71\u54cd\u4e4b\u4e00\u662f\u5176\u9a71\u52a8\u4e86\u591a\u79cd\u65b9\u6cd5\u7684\u8fdb\u6b65\uff0c\u4ee5\u652f\u6301\u5927\u89c4\u6a21\u9057\u4f20\u7f16\u7801\u7a0b\u5e8f\u548c\u57fa\u56e0\u7ec4\u89c4\u6a21\u7684\u5de5\u7a0b\u5316\u6539\u9020\uff0c\u5305\u62ecDNA\u5408\u6210\u3002\u5176\u4ed6\u7684\u8fdb\u5c55\u5305\u62ec\u9610\u660e\u4e86\u652f\u6301\u7406\u6027\u8bbe\u8ba1\u548c\u7cbe\u786e\u57fa\u56e0\u8c03\u63a7\u4e0e\u9176\u4fc3\u6d3b\u52a8\u7684\u6846\u67b6\uff0c\u540c\u65f6\u6211\u4eec\u8fd8\u5728\u63a8\u52a8\u5b9a\u91cf\u6807\u51c6\u5316\u548c\u6570\u636e\u62a5\u544a\u6807\u51c6\u5316\u65b9\u9762\u505a\u51fa\u4e86\u521d\u671f\u7684\u52aa\u529b\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u8fd9\u4e2a\u9886\u57df\u4e00\u4e2a\u5f88\u5927\u7684\u6311\u6218\u662f\u5f00\u53d1\u9ad8\u901a\u91cf\u3001\u65e0\u7834\u574f\u6027\u7684\u91cf\u5316\u6280\u672f\uff0c\u4ee5\u4fbf\u80fd\u591f\u5bf9\u65e0\u6cd5\u901a\u8fc7\u8367\u5149\u86cb\u767d\u4fe1\u53f7\u6d4b\u5b9a\u7684\u751f\u547d\u6d3b\u52a8\u8fdb\u884c\u5b9a\u91cf\u3002\u867d\u7136\u8fd9\u4e2a\u9886\u57df\u6b63\u5728\u8f6c\u5411\u591a\u6837\u6027\u7684\u8bbe\u8ba1\u601d\u8def\uff0c\u4f46\u662f\u81f3\u4eca\u5728\u5f00\u53d1\u523b\u753b\u591a\u6837\u6027\u57fa\u56e0\u7535\u8def\u7684\u6280\u672f\u65b9\u9762\u6211\u4eec\u4ecd\u7136\u6295\u5165\u4e0d\u8db3\u3002\u6b63\u56e0\u5982\u6b64\uff0c\u6211\u4eec\u65e0\u6cd5\u4ece\u5f53\u524d\u7684\u8bbe\u8ba1\u65b9\u6cd5\u4e2d\u6709\u6240\u6536\u83b7\uff0c\u8fd9\u9650\u5236\u4e86\u6211\u4eec\u5411\u66f4\u52a0\u201c\u66f4\u667a\u80fd\u8bbe\u8ba1\u201d\u65b9\u6cd5\u7684\u8f6c\u53d8\uff08\u4e0e\u201c\u66f4\u591a\u8bbe\u8ba1\u201d\u7684\u65b9\u6cd5\u76f8\u6bd4\uff09\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>C.A.V.<\/em><\/span><\/strong>\u5408\u6210\u751f\u7269\u5b66\u9886\u57df\u8fd1\u671f\u591a\u9879\u8fdb\u5c55\u9769\u547d\u6027\u7684\u6539\u53d8\u4e86\u5de5\u7a0b\u5316\u6539\u9020\u7ec6\u80de\u7684\u65b9\u5f0f\u3002DNA\u5408\u6210\u548c\u7ec4\u88c5\u6280\u672f\u4f7f\u5f97\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u5bf9\u4e0a\u767e\u4e07\u78b1\u57fa\u7684\u4efb\u610f\u4e00\u4e2a\u78b1\u57fa\u8fdb\u884c\u64cd\u63a7\u3002\u62112003\u5e74\u505a\u535a\u58eb\u540e\u65f6\u8fd8\u6ca1\u6709\u8fd9\u4e2a\u80fd\u529b\u3002\u4f46\u6211\u4eec\u5229\u7528\u8fd9\u6837\u7684\u80fd\u529b\u6765\u505a\u4ec0\u4e48\u4e5f\u662f\u4e00\u4e2a\u4e0d\u5c0f\u7684\u6311\u6218\u3002\u540c\u65f6\u6211\u4eec\u5728\u57fa\u56e0\u7ec4\u5de5\u7a0b\u5316\u6539\u9020\u548cDNA\u8f6c\u5316\u8fdb\u5165\u7ec6\u80de\u7b49\u6280\u672f\u65b9\u9762\u4e5f\u6709\u4e86\u5f88\u5927\u7684\u8fdb\u6b65\uff0c\u5305\u62ecGeorge Church\u5f00\u53d1\u7684MAGE\u6280\u672f\uff0cCraig Venter\u6784\u5efa\u7684\u4eba\u9020\u57fa\u56e0\u7ec4\uff0c\u57fa\u4e8eCRISPR\u65b9\u6cd5\u7684\u57fa\u56e0\u7ec4\u7f16\u8f91\u6280\u672f\u7b49\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u8bbe\u8ba1\u65b9\u6cd5\u4e5f\u6709\u4e86\u8fdb\u4e00\u6b65\u7684\u53d1\u5c55\u3002\u8bb8\u591a\u5b9e\u9a8c\u5ba4\u4e00\u76f4\u5728\u91cd\u65b0\u601d\u8003\u9057\u4f20\u7cfb\u7edf\u7684\u8bbe\u8ba1\uff0c\u4ee5\u4fbf\u80fd\u591f\u5efa\u7acb\u5173\u8054\u66f4\u591a\u5143\u4ef6\u3001\u590d\u6742\u5ea6\u66f4\u9ad8\u7684\u7cfb\u7edf\u3002\u8bb8\u591a\u5b9e\u9a8c\u5ba4\uff0c\u5305\u62ec\u7f8e\u56fd\u52b3\u4f26\u65af\u4f2f\u514b\u5229\u56fd\u5bb6\u5b9e\u9a8c\u5ba4\uff08LBNL\uff09\u7684BIOFAB\uff0c\u5df2\u7ecf\u6784\u5efa\u4e86\u5927\u91cf\u523b\u753b\u597d\u7684\u57fa\u56e0\u5143\u4ef6\uff0c\u5e76\u4e14\u8fd9\u4e9b\u5143\u4ef6\u53ef\u4ee5\u6574\u5408\u8fdb\u8fd9\u4e9b\u590d\u6742\u7684\u8bbe\u8ba1\u4e4b\u4e2d\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u57fa\u56e0\u7535\u8def\u7684\u8bbe\u8ba1\u80fd\u529b\u4e5f\u5f97\u5230\u4e86\u63d0\u9ad8\u3002\u6211\u4eec\u5df2\u7ecf\u6784\u5efa\u4e86\u8f6c\u5f55\u56e0\u5b50\u7684\u5927\u578b\u6587\u5e93\uff0c\u5e76\u4e14\u5c06\u4ed6\u4eec\u8f6c\u6362\u4e3a\u4e86\u903b\u8f91\u95e8\u57fa\u56e0\u7535\u8def\u3002\u540c\u65f6\u6211\u4eec\u4e5f\u66f4\u52a0\u7406\u89e3\u4e86\u5982\u4f55\u8ba9\u4ed6\u4eec\u5f7c\u6b64\u7edd\u7f18\u4ece\u800c\u4ed6\u4eec\u80fd\u591f\u66f4\u597d\u7684\u7ec4\u6210\u66f4\u5927\u66f4\u590d\u6742\u7684\u57fa\u56e0\u7535\u8def\u3002CRISPR\u5e72\u6270\u6280\u672f\uff08CRISPRi\uff09\u4e3a\u6211\u4eec\u63d0\u4f9b\u4e86\u5173\u95ed\u57fa\u56e0\u8868\u8fbe\u7684\u65b0\u601d\u8def\uff0c\u540c\u65f6\u5176\u7cfb\u7edf\u672c\u8eab\u7684\u6b63\u4ea4\u6027\u4f7f\u5f97\u66f4\u591a\u7684\u8c03\u63a7\u5143\u4ef6\u53ef\u4ee5\u5e94\u7528\u5230\u540c\u4e00\u4e2a\u7ec6\u80de\u4e2d\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u5c31\u5b9e\u9645\u5e94\u7528\u800c\u8a00\uff0c\u5e02\u573a\u4e0a\u5f88\u591a\u4ea7\u54c1\u90fd\u662f\u7531\u57fa\u56e0\u6539\u9020\u7684\u7ec6\u80de\u751f\u4ea7\u7684\u3002\u6765\u81ea\u7f8e\u56fdBiodesic\u516c\u53f8\u7684Rob Carlson\u4f30\u6d4b\u8fd9\u4e2a\u5e02\u573a\u6bcf\u5e74\u4f1a\u67093500\u4ebf\u7f8e\u5143\u7684\u589e\u957f\uff0c\u5927\u7ea6\u5360\u7f8e\u56fd\u7ecf\u6d4e\u76842%\u3002\u5408\u6210\u751f\u7269\u5b66\u65e0\u8bba\u662f\u5bf9\u73b0\u5728\u8fd8\u662f\u4e0b\u4e00\u4ee3\u4ea7\u54c1\u7684\u8d21\u732e\u662f\u975e\u5e38\u5927\u7684\u3002\u5927\u516c\u53f8\u4e2d\u7684\u4e00\u4e9b\u503c\u5f97\u6ce8\u610f\u7684\u4f8b\u5b50\u5305\u62ec\u7f8e\u56fdDow AgroSciences\u7684\u6740\u866b\u5242\uff08\u4f8b\u5982spinosyn\uff09\uff0c\u7f8e\u56fd\u7684Amyris\u548c\u6cd5\u56fd\u7684Sanofi\u7684\u6297\u759f\u9752\u84bf\u7d20\u3002 \u5c0f\u516c\u53f8\u4e5f\u5728\u5f00\u53d1\u4ea7\u54c1\uff0c\u4f8b\u5982\uff0c\u7f8e\u56fd\u7684Genomatica\u516c\u53f8\u751f\u4ea7\u4e01\u4e8c\u9187\uff08BDO\uff09\u548c\u7f8e\u56fd\u7684Refactored Materials\u751f\u4ea7\u91cd\u7ec4\u8718\u86db\u4e1d\u3002\u5176\u5b9e\u6709\u5f88\u591a\u4f8b\u5b50\uff0c\u6211\u5728\u8fd9\u91cc\u53ea\u662f\u5f3a\u8c03\u4e86\u4e00\u4e9b\u3002<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;text-align: center\"><img class=\"\" style=\"width: 543px;height: 301px\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma2-1546606830.jpeg\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/p>\n<p style=\"text-align: center;margin-left: 8px;margin-right: 8px;line-height: 1.75em\"><strong><span>\u5408\u6210\u751f\u7269\u5b66\u7684\u53d1\u5c55\u9a71\u52a8\u4e86\u751f\u7269\u4ea7\u4e1a\u5e73\u53f0\u7684\u5efa\u7acb<\/span><\/strong><\/p>\n<p><span style=\"font-size: 15px\">\u5728\u5e94\u7528\u5c42\u6b21\u4e00\u4e2a\u4e3b\u8981\u7684\u6311\u6218\u662f\u5229\u7528\u7ec6\u80de\u521b\u9020\u66f4\u52a0\u590d\u6742\u7684\u529f\u80fd\u6750\u6599\u3002\u7ec6\u80de\u662f\u5929\u7136\u7684\u539f\u5b50\u7ed3\u6784\uff0c\u73b0\u5728\u5f88\u591a\u6b63\u5728\u4f7f\u7528\u7684\u6750\u6599\u5747\u6e90\u81ea\u751f\u7269\u672c\u8eab\u3002\u4e0a\u9762\u63d0\u5230\u7684\u4f8b\u5b50\u76f8\u5bf9\u6765\u8bf4\u90fd\u662f\u7b80\u5355\u7684\u5316\u5b66\u7269\u8d28\uff0c\u5929\u7136\u4ea7\u7269\u6216\u8005\u5355\u4e00\u7684\u86cb\u767d\u8d28\u3002\u5982\u679c\u60f3\u8981\u83b7\u5f97\u66f4\u52a0\u590d\u6742\u7684\u4ea7\u54c1\u5219\u9700\u8981\u5408\u6210\u66f4\u52a0\u590d\u6742\u7684\u57fa\u56e0\u7535\u8def\uff0c\u540c\u65f6\u9700\u8981\u5bf9\u5f88\u591a\uff0c\u751a\u81f3\u6210\u767e\u4e0a\u5343\u4e2a\u7684\u57fa\u56e0\u8fdb\u884c\u64cd\u63a7\u3002<\/span><\/p>\n<section class=\"editor\">\n<section>\n<section>\n<section>\n<section><\/section>\n<section class=\"mpa-template\">\n<section style=\"margin-top: 20px\">\n<section style=\"min-width: 200px;min-height: 40px;border-right: 2px solid #e6e6e6;border-bottom: 2px solid #e6e6e6;padding: 0 5px 5px 0\">\n<section>\n<section><\/section>\n<section style=\"color: #4f4f4f;line-height: 30px\">\n<section><strong><span>3 \u5408\u6210\u751f\u7269\u5b66\u7684\u4f18\u52bf\u4e0e\u672a\u6765<\/span><\/strong><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em\"><span style=\"font-size: 15px\"><strong><span>\u95ee\uff1a<\/span><\/strong><span>\u5408\u6210\u751f\u7269\u5b66\u7684\u4e00\u4e9b\u5e94\u7528\u5f15\u9886\u4e86\u4e34\u5e8a\u533b\u7597\u3001\u836f\u7269\u4e0e\u751f\u7269\u71c3\u6cb9\u76f8\u5173\u7684\u751f\u7269\u6280\u672f\u7684\u53d1\u5c55\u3002\u5408\u6210\u751f\u7269\u5b66\u65b9\u6cd5\u7684\u4f18\u52bf\u6709\u54ea\u4e9b\uff1f\u4f60\u4eec\u662f\u5982\u4f55\u770b\u5f85\u8fd9\u4e9b\u5e94\u7528\u7684\u672a\u6765\u7684\uff1f<\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em\"><span style=\"font-size: 15px\"><em><strong><span style=\"font-size: 15px\">R.W.<\/span><\/strong><\/em>\u663e\u7136\u5408\u6210\u751f\u7269\u5b66\u5df2\u7ecf\u9769\u547d\u6027\u7684\u6539\u53d8\u4e86\u4ee3\u8c22\u5de5\u7a0b\u9886\u57df\uff0c\u8fd9\u4f7f\u5f97\u751f\u4ea7\u836f\u7269\u6216\u8005\u5c0f\u5206\u5b50\u6210\u4e3a\u53ef\u80fd\u3002\u5c3d\u7ba1\u5728\u8fd9\u4e2a\u9886\u57df\u8fd1\u671f\u6709\u4e86\u5f88\u5927\u7684\u8fdb\u5c55\uff0c\u4f46\u662f\uff0c\u6211\u4e4b\u524d\u4e5f\u8bf4\u8fc7\uff0c\u5176\u5b9e\u81f3\u4eca\u53ea\u6709\u5f88\u5c11\u7684\u5e94\u7528\u6700\u7ec8\u5b9e\u73b0\uff0c\u7279\u522b\u662f\u5bf9\u4e8e\u54fa\u4e73\u52a8\u7269\u5408\u6210\u751f\u7269\u5b66\u9886\u57df\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u7136\u800c\uff0c\u8fd9\u5176\u4e2d\u7684\u539f\u56e0\u53ef\u80fd\u5728\u4e8e\u8fd9\u4e2a\u9886\u57df\u5982\u6b64\u4e4b\u65b0\u3002\u6211\u8ba4\u4e3a\u54fa\u4e73\u52a8\u7269\u5408\u6210\u751f\u7269\u5b66\u672a\u6765\u5c06\u4f1a\u5728\u4e24\u4e2a\u9886\u57df\u6709\u7740\u5e7f\u9614\u7684\u5e94\u7528\u524d\u666f\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u7b2c\u4e00\u4e2a\u9886\u57df\u662f\u5229\u7528\u4f17\u591a\u8fd1\u671f\u5f00\u53d1\u7684\u57fa\u56e0\u7ec4\u5de5\u7a0b\u5de5\u5177\u521b\u9020\u4e0b\u4e00\u4ee3\u7f16\u7a0b\u5316\u7684\u54fa\u4e73\u52a8\u7269\u7ec6\u80de\u7cfb\uff0c\u4ee5\u4ea7\u751f\u66f4\u52a0\u91cf\u8eab\u5b9a\u5236\u7684\u5148\u8fdb\u751f\u7269\u5236\u5242\u3002\u54fa\u4e73\u52a8\u7269\u5408\u6210\u751f\u7269\u5b66\u754c\u548c\u751f\u7269\u533b\u836f\u5de5\u4e1a\u7684\u7d27\u5bc6\u5408\u4f5c\u4f1a\u8ba9\u8fd9\u4e2a\u9886\u57df\u6781\u5927\u7684\u53d7\u76ca\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u7b2c\u4e8c\u4e2a\u9886\u57df\u662f\u521b\u5efa\u80fd\u591f\u5339\u914d\u751f\u7269\u7cfb\u7edf\u590d\u6742\u5ea6\u7684\u57fa\u56e0\u7535\u8def\u7597\u6cd5\u3002\u7cfb\u7edf\u751f\u7269\u5b66\u6b63\u5728\u5e2e\u52a9\u6211\u4eec\u63ed\u79d8\u751f\u7269\u7f51\u7edc\u4e4b\u95f4\u7684\u8c03\u63a7\u65b9\u5f0f\u548c\u76f8\u4e92\u4f5c\u7528\u5173\u7cfb\uff0c\u4ece\u800c\u7834\u8bd1\u751f\u7269\u4f53\u7684\u590d\u6742\u6027\u3002\u4e0d\u8fc7\u8fd9\u4e5f\u6559\u5bfc\u6211\u4eec\uff1a\u50cf\u764c\u75c7\u3001\u4ee3\u8c22\u75be\u75c5\u3001\u514d\u75ab\u75be\u75c5\u3001\u795e\u7ecf\u75be\u75c5\u6216\u8005\u5fc3\u7406\u7d0a\u4e71\u8fd9\u4e9b\u751f\u7269\u75be\u75c5\u672c\u8eab\u662f\u76f8\u5173\u6df1\u5965\u548c\u590d\u6742\u7684\u3002\u6211\u8ba4\u4e3a\u590d\u6742\u7684\u75be\u75c5\u6700\u597d\u662f\u5229\u7528\u590d\u6742\u7684\u5408\u6210\u57fa\u56e0\u7535\u8def\u8c03\u8282\u8eab\u4f53\u6765\u8fbe\u5230\u6700\u597d\u7684\u6cbb\u7597\u3002\u968f\u7740\u7814\u7a76\u6b65\u4f10\u7684\u52a0\u901f\uff0c\u54fa\u4e73\u52a8\u7269\u5408\u6210\u751f\u7269\u5b66\u5f88\u5feb\u5c31\u4f1a\u6709\u6807\u5fd7\u6027\u7684\u5e94\u7528\u4ece\u800c\u8d62\u5f97\u5927\u4f17\u7684\u652f\u6301\u548c\u4fe1\u4efb\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>G.M.C.<\/em><\/span><\/strong>\u5177\u4f53\u7684\u5e94\u7528\u5b9e\u4f8b\u5305\u62ecAmyris\u548cSanofi\u5bf9\u6297\u759f\u836f\u9752\u84bf\u7d20\u7684\u9ad8\u6548\u751f\u7269\u751f\u4ea7\u3001\u7f8e\u56fdLS9\u548cJoule Unlimited\u5bf9\u77f3\u6cb9\u7684\u201c\u7eff\u8272\u5316\u5b66\u201d\u66ff\u4ee3\u65b9\u6848\u3002\u672a\u6765\uff0c\u6211\u4eec\u5c06\u770b\u5230\u8d8a\u6765\u8d8a\u591a\u7684\u5408\u6210\u751f\u7269\u5b66\u7528\u4e8e\u533b\u7597\uff1a\u4ece\u968f\u673a\u8f6c\u57fa\u56e0\u63d2\u5165\u8f6c\u5411\u7cbe\u51c6\u57fa\u56e0\u7ec4\u7f16\u8f91; \u4ece\u6297\u751f\u7d20\u5730\u6bef\u8f70\u70b8\u5230\u80a0\u9053\u5fae\u751f\u7269\u7597\u6cd5; \u751f\u7269\u7eb3\u7c73\u6750\u6599\u80fd\u591f\u5b9e\u73b0\u539f\u5b50\u7ea7\u522b\u7684\u7cbe\u786e\u5ea6\uff0c\u6bd4\u5f53\u524d\u7535\u5b50\u7535\u8def\u5904\u7406\u4fe1\u606f\u7684\u80fd\u529b\u9ad8\u51fa\u4e00\u767e\u4e07\u500d\u4ee5\u4e0a\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>M.B.E.<\/em><\/span><\/strong>\u6240\u6709\u8fd9\u4e9b\u9886\u57df\u7684\u5de5\u4f5c\u662f\u6781\u5176\u4ee4\u4eba\u5174\u594b\u7684\u3002\u5c3d\u7ba1\u6211\u4eec\u5df2\u7ecf\u6210\u529f\u5229\u7528\u5de5\u7a0b\u5316\u6539\u9020\u7684\u5fae\u751f\u7269\u6765\u751f\u4ea7\u91cd\u8981\u7684\u4ea7\u54c1\uff0c\u4f46\u662f\u8fd9\u4e9b\u5e73\u53f0\u90fd\u662f\u5728\u4e25\u683c\u63a7\u5236\u7684\u5b9e\u9a8c\u5ba4\u6761\u4ef6\u4e0b\u8bbe\u8ba1\u7684\u3002\u4e00\u4e2a\u5173\u952e\u7684\u6311\u6218\u662f\u5f04\u6e05\u695a\u5982\u4f55\u4f7f\u5de5\u7a0b\u5316\u6539\u9020\u7ec6\u80de\u80fd\u591f\u5728\u590d\u6742\u7684\u81ea\u7136\u73af\u5883\u4e2d\u53d1\u6325\u4f5c\u7528\uff0c\u5305\u62ec\u4eba\u7c7b\u7684\u8eab\u4f53\u5185\u3002\u6211\u4eec\u9700\u8981\u638c\u63e1\u8bbe\u8ba1\u591a\u57fa\u56e0\u57fa\u56e0\u7535\u8def\u7684\u80fd\u529b\uff0c\u5c06\u5b83\u4eec\u7cbe\u786e\u7684\u6574\u5408\u8fdb\u7ec6\u80de\u5185\u90e8\uff0c\u5e76\u4e14\u80fd\u591f\u5b9a\u91cf\u7684\u63a7\u5236\u5b83\u4eec\u7684\u884c\u4e3a\u3002\u76ee\u524d\uff0c\u8fdb\u5c55\u8fc7\u7a0b\u4ecd\u7136\u4e4f\u5473\u7f13\u6162\uff0c\u5e76\u4e14\u8fd9\u6781\u5927\u5730\u9650\u5236\u4e86\u6211\u4eec\u53ef\u63a2\u7d22\u7684\u60f3\u6cd5\u548c\u8bbe\u8ba1\u65b9\u6848\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u8bdd\u867d\u5982\u6b64\uff0c\u6211\u8ba4\u4e3a\u5f88\u591a\u95ee\u9898\u5176\u5b9e\u90fd\u662f\u53ef\u4ee5\u89e3\u51b3\u7684\u3002\u60f3\u8c61\u4e00\u4e0b\uff0c\u5f53\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u5e38\u89c4\u7684\u8bfb\u53d6\u548c\u63a7\u5236\u7ec6\u80de\u4e2d\u591a\u5c42\u76f8\u4e92\u4f5c\u7528\u7684\u57fa\u56e0\u548c\u86cb\u767d\u8d28\u7cfb\u7edf\u65f6\u5c06\u4f1a\u53d1\u751f\u4ec0\u4e48\u2014\u2014\u8fd9\u5c06\u663e\u8457\u7684\u6539\u53d8\u57fa\u56e0\u5de5\u7a0b\u9886\u57df\u7684\u73b0\u72b6\uff0c\u5c06\u5e38\u89c4\u57fa\u56e0\u5de5\u7a0b\u7684\u5355\u4f4d\u4ece\u57fa\u56e0\u6539\u53d8\u4e3a\u57fa\u56e0\u7535\u8def\uff01<\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>C.D.S.<\/em><\/span><\/strong>\u5408\u6210\u751f\u7269\u5b66\u6b63\u5728\u4e3a\u4e34\u5e8a\u7597\u6cd5\u548c\u751f\u7269\u6280\u672f\u5e26\u6765\u65b0\u7684\u5de5\u5177\u548c\u65b9\u6cd5\u3002\u5408\u6210\u751f\u7269\u5b66\u4e0d\u4ec5\u5728\u63a8\u8fdb\u751f\u7269\u5408\u6210\u8fc7\u7a0b\u7684\u590d\u6742\u5ea6\uff0c\u540c\u65f6\u4e5f\u5728\u63d0\u9ad8\u901a\u8fc7\u751f\u7269\u8fc7\u7a0b\u751f\u4ea7\u7684\u5206\u5b50\u7684\u591a\u6837\u6027\u3002\u5229\u7528\u751f\u7269\u81ea\u8eab\u5f3a\u5927\u7684\u751f\u4ea7\u80fd\u529b\u5728\u672a\u6765\u5c06\u4f1a\u662f\u4e00\u4e2a\u5de8\u5927\u7684\u673a\u9047\uff0c\u8fd9\u5c06\u4e3a\u6211\u4eec\u5e26\u6765\u66f4\u52a0\u590d\u6742\u7684\u751f\u7269\u4ea7\u54c1\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u6211\u4eec\u8fd8\u53ef\u4ee5\u901a\u8fc7\u4ee5\u4e00\u4e2a\u52a8\u6001\u7684\u3001\u5c40\u57df\u6027\u7684\u65b9\u5f0f\u63a7\u5236\u60a3\u8005\u6cbb\u7597\u8fc7\u7a0b\u4e2d\u836f\u7269\u7684\u8f93\u9001\u548c\u5242\u91cf\u6765\u5f00\u53d1\u66f4\u52a0\u5b89\u5168\u548c\u9ad8\u6548\u7684\u4e34\u5e8a\u7597\u6cd5\u3002\u76ee\u524d\u7684\u52aa\u529b\u96c6\u4e2d\u5728\u57fa\u4e8e\u7ec6\u80de\u7684\u5e73\u53f0\u5305\u62ec\u514d\u75ab\u7597\u6cd5\u548c\u76ca\u751f\u83cc\u3002\u968f\u7740\u6280\u672f\u7684\u4e0d\u65ad\u8fdb\u6b65\uff0c\u5408\u6210\u751f\u7269\u5b66\u5728\u4e34\u5e8a\u4e0a\u7684\u957f\u671f\u5e94\u7528\u8fd8\u5c06\u5ef6\u4f38\u5230\u7ec4\u7ec7\u5de5\u7a0b\u548c\u518d\u751f\u533b\u5b66\u9886\u57df\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>C.A.V.<\/em><\/span><\/strong>\u5728\u77ed\u671f\u5185\uff0c\u5408\u6210\u751f\u7269\u5b66\u5f00\u53d1\u7684\u5de5\u5177\u53ef\u4ee5\u76f4\u63a5\u88ab\u7528\u6765\u5f00\u53d1\u5929\u7136\u4ea7\u7269\uff0c\u5305\u62ec\u751f\u7269\u533b\u836f\uff0c\u4eba\u7c7b\u589e\u5f3a\u836f\u7269\uff0c\u5de5\u4e1a\u5316\u5b66\u4ea7\u54c1\uff0c\u80fd\u6e90\u548c\u519c\u4e1a\u4ea7\u54c1\uff08\u4f8b\u5982\uff0c\u6740\u866b\u5242\u548c\u519c\u836f\uff09\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u5229\u7528\u81ea\u7136\u591a\u6837\u6027\u7684\u6f5c\u529b\u662f\u5de8\u5927\u7684\u3002\u81ea\u7136\u7684\u591a\u6837\u6027\u5b58\u5728\u4e8e\u5927\u91cf\u7684\u83cc\u79cd\u548cDNA\u5e8f\u5217\u6570\u636e\u5e93\u4e2d\u3002\u6211\u4eec\u73b0\u5728\u53ef\u4ee5\u5f88\u5bb9\u6613\u83b7\u5f97\u751f\u7269\u7684DNA\u4fe1\u606f\u3002\u751f\u7269\u4fe1\u606f\u5b66\u53ef\u4ee5\u9884\u6d4b\u80fd\u591f\u7528\u6765\u751f\u4ea7\u9ad8\u9644\u52a0\u503c\u5316\u5b66\u7269\u8d28\u7684\u57fa\u56e0\u7c07\u3002DNA\u5408\u6210\u6280\u672f\u4f7f\u5f97\u5e8f\u5217\u4fe1\u606f\u80fd\u591f\u8f6c\u6362\u4e3a\u7269\u7406DNA\uff0c\u7136\u800c\uff0c\u5728\u751f\u7269\u4e2d\u8fd9\u4e9b\u5408\u6210\u7684DNA\u5f80\u5f80\u5bb9\u6613\u4e22\u5931\u6216\u8005\u4e0d\u80fd\u591f\u88ab\u64cd\u63a7\u6216\u8005\u57fa\u56e0\u672c\u8eab\u5728\u751f\u7269\u4f53\u5185\u5c31\u662f\u88ab\u6c89\u9ed8\u6389\u7684\u3002\u514b\u670d\u8fd9\u4e9b\u56f0\u96be\u9700\u8981\u5408\u6210\u751f\u7269\u5b66\u5f00\u53d1\u76f8\u5e94\u7684\u8c03\u63a7\u5de5\u5177\u3002 \u6211\u4eec\u6b63\u5904\u4e8e\u6316\u6398\u6570\u636e\u5e93\u4ee5\u5f00\u53d1\u6709\u4ef7\u503c\u4ea7\u54c1\u8fd9\u79cd\u6dd8\u91d1\u70ed\u7684\u65e9\u671f\u9636\u6bb5\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u540c\u65f6\u5bf9\u9176\u7684\u6df1\u5ea6\u63a2\u7d22\uff08\u6570\u636e\u5e93\u57fa\u56e0\u7684\u9ad8\u901a\u91cf\u641c\u5bfb\u3001\u6253\u5370\u548c\u7b5b\u9009\uff09\u4e5f\u662f\u5f88\u91cd\u8981\u7684\uff0c\u8fd9\u4f7f\u5f97\u53ef\u751f\u4ea7\u7684\u5316\u5b66\u7269\u8d28\u5448\u73b0\u591a\u6837\u6027\u3002\u8fd9\u5c06\u5e26\u9886\u6211\u4eec\u5b9e\u73b0\u8fd9\u6837\u7684\u68a6\u60f3\uff1a\u9176\u50ac\u5316\u5c31\u50cf\u5316\u5b66\u5408\u6210\u4e00\u6837\u7075\u6d3b\u591a\u53d8\uff0c\u53ef\u4ee5\u50ac\u5316\u5408\u6210\u4efb\u610f\u5316\u5b66\u7ed3\u6784\u3002\u540c\u65f6\u7ec6\u80de\u7597\u6cd5\u5c06\u4f1a\u62e5\u6709\u5de8\u5927\u7684\u4f18\u52bf\uff1a\u5176\u4e0d\u4ec5\u5177\u6709\u611f\u5e94\u548c\u5904\u7406\u4fe1\u53f7\u7684\u80fd\u529b\u5e76\u4e14\u80fd\u591f\u5728\u76ee\u6807\u9776\u70b9\u5408\u6210\u591a\u79cd\u5316\u5b66\u548c\u86cb\u767d\u6548\u5e94\u56e0\u5b50\u3002<\/span><\/p>\n<section class=\"editor\">\n<section>\n<section>\n<section>\n<section class=\"mpa-template\">\n<section style=\"margin-top: 20px\">\n<section style=\"min-width: 200px;min-height: 40px;border-right: 2px solid #e6e6e6;border-bottom: 2px solid #e6e6e6;padding: 0 5px 5px 0\">\n<section>\n<section><\/section>\n<section style=\"color: #4f4f4f;line-height: 30px\">\n<section><strong><span>4 \u5408\u6210\u751f\u7269\u5b66\u7684\u4f26\u7406\u4e0e\u76d1\u7ba1<\/span><\/strong><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"line-height: 1.75em;margin-left: 8px;margin-right: 8px\"><span style=\"font-size: 15px\"><strong><span>\u95ee\uff1a<\/span><\/strong><span>\u6280\u672f\u7684\u8fdb\u6b65\u4f7f\u5f97\u201c\u4e66\u5199\u201d\u6574\u4e2a\u57fa\u56e0\u7ec4\u6210\u4e3a\u53ef\u80fd\u3002\u7136\u800c\uff0c\u521b\u9020\u4eba\u9020\u751f\u547d\u5f62\u5f0f\u7684\u53ef\u80fd\u6027\u5df2\u7ecf\u5f15\u8d77\u516c\u4f17\u5e7f\u6cdb\u7684\u62c5\u5fe7\u3002\u5408\u6210\u751f\u7269\u5b66\u9886\u57df\u9762\u4e34\u7740\u4ec0\u4e48\u6837\u7684\u6311\u6218\uff0c\u54ea\u4e9b\u662f\u5fc5\u987b\u89e3\u51b3\u7684\u4f26\u7406\u548c\u76d1\u7ba1\u95ee\u9898\uff1f<\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>R.W.<\/em><\/span><\/strong>\u521b\u9020\u4e00\u4e2a\u65b0\u7684\u751f\u547d\u5f62\u5f0f\u662f\u5f88\u6709\u8da3\u7684\u2014\u2014\u5e76\u4e14\u6211\u8ba4\u4e3a\u8fd9\u6700\u7ec8\u662f\u6709\u53ef\u80fd\u7684\u3002\u7136\u800c\uff0c\u5927\u591a\u6570\u5408\u6210\u751f\u7269\u5b66\u9879\u76ee\u90fd\u662f\u5728\u7ec6\u83cc\uff0c\u9175\u6bcd\u6216\u54fa\u4e73\u52a8\u7269\u7ec6\u80de\u6dfb\u52a0\u65b0\u7684\u529f\u80fd\uff0c\u56e0\u4e3a\u8fd9\u5bf9\u751f\u7269\u6280\u672f\u5de5\u4e1a\u6709\u5f88\u5927\u7528\u5904\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u6211\u4eec\u8bd5\u56fe\u901a\u8fc7\u6b63\u5411\u57fa\u56e0\u5de5\u7a0b\u6765\u63d0\u9ad8\u6807\u51c6\u5316\u7684\uff0c\u523b\u753b\u4f18\u826f\u7684\u7ec6\u80de\u7cfb\u7684\u591a\u6837\u6027\u548c\u5e94\u7528\u4ef7\u503c\u3002\u5728\u54fa\u4e73\u52a8\u7269\u5408\u6210\u751f\u7269\u5b66\u4e2d\uff0c\u751f\u7269\u6cbb\u7597\u65b9\u6848\u5c06\u9700\u8981\u5728\u4efb\u4f55\u76d1\u7ba1\u6279\u51c6\u4e4b\u524d\u4fdd\u8bc1\u5b89\u5168\u6027\uff0c\u540c\u65f6\u75c5\u6bd2\u8f7d\u4f53\u80fd\u591f\u6709\u6548\u7684\u5c06DNA\u57fa\u56e0\u7535\u8def\u9012\u9001\u5230\u76ee\u6807\u9776\u70b9\u3002\u6211\u4eec\u5df2\u7ecf\u770b\u5230\u4e00\u4e2a\u6709\u524d\u666f\u7684\u7ed3\u679c\uff1aRNA\u57fa\u56e0\u7535\u8def\u53ef\u4ee5\u4f5c\u4e3a\u4e00\u4e2a\u5b89\u5168\u7684\u66ff\u4ee3\u65b9\u6848\u3002\u6b64\u5916\uff0c\u76f8\u6bd4\u4e8e\u7528\u4e8e\u836f\u7269\u5f00\u53d1\u548c\u8bca\u65ad\u7684\u52a8\u7269\u6a21\u578b\uff0c\u53ef\u7f16\u7a0b\u7684\u201corgans-on-a-chip\u201d\u53ef\u4ee5\u63d0\u4f9b\u4e00\u4e2a\u66f4\u63a5\u8fd1\u4eba\u7c7b\u5b9e\u9645\u60c5\u51b5\u7684\u66ff\u4ee3\u65b9\u6848\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u50cf\u5176\u4ed6\u8d1f\u8d23\u4efb\u7684\u79d1\u5b66\u9886\u57df\u4e00\u6837\uff0c\u5408\u6210\u751f\u7269\u5b66\u6709\u4e00\u79cd\u6839\u6df1\u8482\u56fa\u7684\u6587\u5316\uff1a\u6211\u4eec\u4e00\u76f4\u5728\u9884\u6d4b\u3001\u907f\u514d\u548c\u964d\u4f4e\u6280\u672f\u5e26\u6765\u7684\u98ce\u9669\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>G.M.C.<\/em><\/span><\/strong>\u5408\u6210\u751f\u7269\u5b66\u73b0\u5728\u9762\u4e34\u7684\u95ee\u9898\u53ef\u4ee5\u8ffd\u6eaf\u5230DNA\u91cd\u7ec4\u6280\u672f\u7684\u5f00\u59cb\u9636\u6bb5\uff0c\u90a3\u65f6\u5019Paul Berg\u548cRudy Jaenisch\u57281973\u5e74\u5c06SV40\u80bf\u7624\u75c5\u6bd2\u63d2\u5165\u5230\u4e86\u7ec6\u83cc\u548c\u5c0f\u9f20\u4e2d\u3002\u51e0\u5341\u5e74\u6765\uff0c\u5206\u5b50\u751f\u7269\u5b66\u5bb6\u5728\u590d\u6742\u7684\u751f\u7269\u7cfb\u7edf\u4e2d\u7528\u57fa\u7840\u7684\u6280\u672f\u7814\u7a76\u5355\u4e2a\u57fa\u56e0\u3002\u73b0\u5728\u5408\u6210\u751f\u7269\u5b66\u5219\u5c06\u7cfb\u7edf\u8bbe\u8ba1\u548c\u5de5\u7a0b\u5b89\u5168\u6027\u5f15\u5165\u751f\u7269\u5b66\u4e2d\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u6211\u4eec\u53ef\u4ee5\u6700\u7ec8\u6784\u5efa\u57fa\u56e0\u7ec4\u91cd\u7f16\u7a0b\u7684\u751f\u7269\uff0c\u8fd9\u4e9b\u751f\u7269\u65e0\u6cd5\u4e0e\u81ea\u7136\u7684\u57fa\u56e0\u7ec4\u76f8\u4e92\u4ea4\u6d41\u3002\u53e6\u4e00\u65b9\u9762\uff0c\u7528\u6765\u63a7\u5236\u5bb3\u866b\u3001\u75be\u75c5\u6216\u8005\u5165\u4fb5\u751f\u7269\u7684\u57fa\u56e0\u4e5f\u65e0\u6cd5\u4e0e\u5929\u7136\u7684\u57fa\u56e0\u7ec4\u4ea7\u751f\u5173\u7cfb\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>M.B.E.<\/em><\/span><\/strong>\u6211\u4eec\u5bf9\u4e8e\u5408\u6210\u751f\u7269\u5b66\u6280\u672f\u5c06\u4f1a\u5e26\u6765\u4ec0\u4e48\u548c\u4e0d\u4f1a\u5e26\u6765\u4ec0\u4e48\u4e86\u89e3\u7684\u8fd8\u6709\u8fdc\u8fdc\u4e0d\u591f\u3002\u6211\u5c24\u5176\u62c5\u5fc3\u516c\u4f17\u5bf9\u4e8e\u5408\u6210\u751f\u7269\u5b66\u7684\u8bef\u5bfc\uff0c\u540c\u65f6\u8fd9\u79cd\u8bef\u5bfc\u53ef\u80fd\u4f1a\u968f\u7740\u7092\u4f5c\u800c\u9010\u6e10\u589e\u52a0\u3002\u65af\u6d1b\u6069\u57fa\u91d1\u4f1a\u548c\u7f8e\u56fd\u56fd\u5bb6\u79d1\u5b66\u9662\u7b49\u5df2\u7ecf\u4f5c\u51fa\u4e86\u5de8\u5927\u7684\u52aa\u529b\u6765\u6539\u5584\u548c\u5927\u4f17\u4e4b\u95f4\u7684\u4fe1\u606f\u9e3f\u6c9f\u3002\u6211\u4eec\u79d1\u5b66\u5bb6\u5fc5\u987b\u4e00\u8d77\u884c\u52a8\u6765\u201cKeep it real\u201d\uff0c\u4ee5\u73b0\u5b9e\u4e3a\u57fa\u7840\uff0c\u5c06\u5173\u6ce8\u70b9\u653e\u5728\u6700\u5173\u952e\u7684\u98ce\u9669\u4e0a\uff0c\u8ba9\u66f4\u5927\u7684\u56e2\u4f53\u53c2\u4e0e\u8fdb\u6765\uff0c\u5229\u7528\u597d\u6211\u4eec\u73b0\u4eca\u62e5\u6709\u7684\u6bcf\u4e00\u9879\u8d44\u6e90\u4e3a\u5408\u6210\u751f\u7269\u5b66\u7684\u53d1\u5c55\u505a\u51fa\u52aa\u529b\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>C.D.S.<\/em><\/span><\/strong>\u901a\u8fc7DNA\u5408\u6210\u6280\u672f\u521b\u9020\u9057\u4f20\u7cfb\u7edf\u7684\u8fdb\u5c55\u5df2\u7ecf\u8fdc\u8fdc\u8d85\u8fc7\u4e86\u8bbe\u8ba1\u8fd9\u4e9b\u7cfb\u7edf\u7684\u8fdb\u5c55\u3002\u5c3d\u7ba1\u6211\u4eec\u80fd\u591f\u6784\u5efa\u5408\u6210\u7684\u57fa\u56e0\u7ec4\uff0c\u4f46\u662f\u6211\u4eec\u8fd8\u8fdc\u8fdc\u6ca1\u6709\u8fbe\u5230\u8bbe\u8ba1\u65b0\u7684\u57fa\u56e0\u7ec4\u6c34\u5e73\u57fa\u56e0\u7a0b\u5e8f\u7684\u80fd\u529b\uff0c\u66f4\u4e0d\u7528\u63d0\u5408\u6210\u5168\u65b0\u7684\u751f\u547d\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u7136\u800c\uff0c\u5728\u9053\u5fb7\u548c\u76d1\u7ba1\u5c42\u9762\u5bf9\u5de5\u7a0b\u5316\u6539\u9020\u7684\u751f\u7269\u7684\u62c5\u5fc3\u4ecd\u7136\u662f\u9700\u8981\u7684\u3002\u9053\u5fb7\u548c\u7ba1\u7406\u5c42\u9762\u7684\u62c5\u5fc3\u53d6\u51b3\u4e8e\u5408\u6210\u751f\u7269\u5b66\u6f5c\u5728\u7684\u5e94\u7528\u3002\u4f8b\u5982\uff0c\u5982\u679c\u751f\u7269\u88ab\u7528\u5728\u5b9e\u9a8c\u5916\u7684\u73af\u5883\u4e2d\uff0c\u90a3\u4e48\u6211\u4eec\u5c31\u5e94\u8be5\u8003\u8651\u5176\u5bf9\u4e8e\u73af\u5883\u548c\u751f\u6001\u7cfb\u7edf\u7684\u6f5c\u5728\u5f71\u54cd\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><span style=\"font-size: 15px\"><em>C.A.V.<\/em><\/span><\/strong>\u8fd9\u4e2a\u9886\u57df\u9700\u8981\u7528\u4e0d\u540c\u7684\u65b9\u6cd5\u6765\u8fdb\u884c\u98ce\u9669\u5206\u7c7b\u4ee5\u53ca\u4ea7\u54c1\u7ba1\u7406\u3002\u4f8b\u5982\uff0c\u76ee\u524dFDA\u548cUSDA\u7684\u7ba1\u7406\u7ed3\u6784\u5e76\u4e0d\u5229\u4e8e\u6709\u6548\u8bc4\u4f30\u9ad8\u5ea6\u5de5\u7a0b\u5316\u7684\u751f\u7269\u5bf9\u4eba\u4f53\u6216\u8005\u76f8\u5173\u533b\u7597\u9886\u57df\u7684\u5f71\u54cd\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\">\u8fd9\u4e2a\u9886\u57df\u6b63\u5728\u91c7\u53d6\u79ef\u6781\u7684\u65b9\u6cd5\u6765\u89e3\u51b3\u8fd9\u4e9b\u95ee\u9898\u3002\u8fd9\u65b9\u9762\u7684\u8ba8\u8bba\u548c\u7814\u7a76\u4e00\u76f4\u5f88\u79ef\u6781\u3002<\/span><\/p>\n<\/p>\n<section class=\"mpa-template\">\n<section style=\"margin-top: 20px\">\n<section>\n<section>\n<section><\/section>\n<section style=\"color: #4f4f4f;line-height: 30px\">\n<section><strong><span>\u4e94\u4f4d\u79d1\u5b66\u5bb6\u7b80\u4ecb<\/span><\/strong><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><strong><span><em><img class=\"\" style=\"width: 540px;height: 360px\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma3-1546606831.jpeg\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/em><\/span><\/strong><\/p>\n<p><strong><span><em>George M. Church (G.M.C.)<\/em><\/span><\/strong><\/p>\n<ul class=\"list-paddingleft-2\" style=\"margin-left: 8px;margin-right: 8px\">\n<li>\n<p style=\"line-height: 1.75em\"><span style=\"font-size: 15px\">\u54c8\u4f5b\u5927\u5b66\u9057\u4f20\u5b66\u6559\u6388, \u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\uff08NIH\uff09\u57fa\u56e0\u79d1\u5b66\u5353\u8d8a\u4e2d\u5fc3\u8d1f\u8d23\u4eba\uff0c\u7f8e\u56fd\u56fd\u5bb6\u79d1\u5b66\u9662\u548c\u7f8e\u56fd\u56fd\u5bb6\u5de5\u7a0b\u9662\u9662\u58eb\uff0c<span class=\"invisible\" style=\"line-height: 0;font-family: a;color: transparent\">http:\/\/<\/span><span class=\"visible\">PersonalGenomes.org<\/span><span class=\"invisible\" style=\"line-height: 0;font-family: a;color: transparent\"><\/span><span class=\"icon-external\" style=\"line-height: 1;font-family: icomoon !important\"><\/span>\u7f51\u7ad9(\u4e16\u754c\u4e0a\u552f\u4e00\u7684\u5f00\u653e\u5f0f\u4eba\u7c7b\u57fa\u56e0\u7ec4\u548c\u7279\u5f81\u6570\u636e\u5e93)\u7684\u8d1f\u8d23\u4eba\uff0c\u5171\u53d1\u8868\u8bba\u6587300\u4f59\u7bc7\uff0c\u4e13\u522960\u4f59\u9879\uff0c\u51fa\u7248\u8fc7\u56fe\u4e66\u4e00\u672c\uff1a\u300aRegenesis\u300b\u3002\u4ed6\u7684\u535a\u58eb\u5b66\u4f4d\uff081984\u5e74\u6388\u4e88\uff09\u6240\u4f7f\u7528\u7684\u65b9\u6cd5\u63a8\u52a8\u4e861994\u5e74\u7684\u7b2c\u4e00\u4e2a\u5fae\u751f\u7269\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u7684\u5b8c\u6210\u3002\u4ed6\u5728\u201c\u4e0b\u4e00\u4ee3\u201d\u6d4b\u5e8f\uff0c\u5be1\u6838\u82f7\u9178\u5408\u6210\u548c\u7ec6\u80de\u5de5\u7a0b\u7b49\u65b9\u9762\u7684\u5de5\u4f5c\u4fc3\u8fdb\u4e86\u533b\u7597\u8bca\u65ad\uff0c\u751f\u7269\u533b\u7597\u548c\u5408\u6210\u5316\u5b66\u54c1\u7684\u53d1\u5c55\uff0c\u540c\u65f6\u4ed6\u4e5f\u5728\u63a8\u52a8\u4eba\u7c7b\u9690\u79c1\uff0c\u751f\u7269\u5b89\u5168\u7b49\u76f8\u5173\u653f\u7b56\u4e2d\u505a\u51fa\u8d21\u732e\u3002<\/span><\/p>\n<\/li>\n<\/ul>\n<p style=\"margin-left: 8px;margin-right: 8px;text-align: center\"><img class=\"\" style=\"width: 540px;height: 370px\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma10-1546606831.jpeg\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/p>\n<p><span style=\"font-size: 15px\"><strong><em><span style=\"font-size: 15px\">Michael B. Elowitz (M.B.E.)<\/span><\/em><\/strong><\/span><\/p>\n<ul class=\"list-paddingleft-2\" style=\"margin-left: 8px;margin-right: 8px\">\n<li>\n<p style=\"line-height: 1.75em\"><span style=\"font-size: 15px\">\u7f8e\u56fd\u5e15\u8428\u8fea\u7eb3\u52a0\u5229\u798f\u5c3c\u4e9a\u7406\u5de5\u5b66\u9662\uff08Caltech\uff09\u970d\u534e\u5fb7\u00b7\u4f11\u65af\u533b\u5b66\u7814\u7a76\u6240\u548c\u751f\u7269\u5b66\uff0c\u751f\u7269\u5de5\u7a0b\u548c\u5e94\u7528\u7269\u7406\u5b66\u6559\u6388\u7684\u7814\u7a76\u5458\u3002\u4ed6\u521b\u5efa\u4e86\u4e00\u4e2a\u7ecf\u5178\u7684\u632f\u8361\u57fa\u56e0\u7535\u8defRepressilator\uff0c\u5e76\u5c55\u793a\u4e86\u5982\u4f55\u5728\u5355\u4e2a\u7ec6\u80de\u4e2d\u5206\u6790\u57fa\u56e0\u8868\u8fbe\u201c\u566a\u97f3\u201d\u53ca\u5176\u529f\u80fd\u3002\u4ed6\u7684\u5b9e\u9a8c\u5ba4\u5229\u7528\u5408\u6210\u751f\u7269\u5b66\uff0c\u5b9a\u91cf\u5ef6\u65f6\u5f71\u50cf\u548c\u6570\u5b66\u5efa\u6a21\u6765\u7406\u89e3\u7ec6\u80de\u548c\u7ec4\u7ec7\u4e2d\u57fa\u56e0\u7535\u8def\u7684\u8bbe\u8ba1\u539f\u7406\uff0c\u7814\u7a76\u8303\u56f4\u5305\u62ec\u4ece\u7ec6\u83cc\u5230\u54fa\u4e73\u52a8\u7269\u7ec6\u80de\u7b49\u591a\u79cd\u7cfb\u7edf\u3002\u4ed6\u662f\u9ea6\u514b\u963f\u745f\u5956\u53ca\u4eba\u7c7b\u524d\u6cbf\u79d1\u5b66\u8ba1\u5212\uff08HFSP\uff09\u4e2d\u66fe\u6839\u5956\u7684\u83b7\u5f97\u8005\u3002<\/span><\/p>\n<p><span style=\"font-size: 15px\"><\/span><\/p>\n<\/li>\n<\/ul>\n<p><span style=\"font-size: 15px\"><strong><em><span style=\"font-size: 15px\"><img class=\"\" style=\"width: 541px;height: 327px\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma2-1546606831.jpeg\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/span><\/em><\/strong><\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><em><span style=\"font-size: 15px\">Christina D. Smolke (C.D.S.)<\/span><\/em><\/strong><\/span><\/p>\n<ul class=\"list-paddingleft-2\" style=\"margin-left: 8px;margin-right: 8px\">\n<li>\n<p style=\"line-height: 1.75em\"><span style=\"font-size: 15px\">\u7f8e\u56fd\u52a0\u5dde\u65af\u5766\u798f\u5927\u5b66\u751f\u7269\u5de5\u7a0b\u7cfb\u526f\u6559\u6388\uff0c\u6559\u80b2\u526f\u4e3b\u5e2d\u548cWilliam M. Keck\u57fa\u91d1\u4f1a\u5b66\u8005\u3002\u5979\u7684\u7814\u7a76\u5f00\u53d1\u4e86\u57fa\u7840\u5de5\u5177\uff0c\u63a8\u52a8\u4e86\u6211\u4eec\u5de5\u7a0b\u5316\u6539\u9020\u548c\u8bbe\u8ba1\u751f\u7269\u7684\u80fd\u529b\u7684\u8fdb\u6b65\u3002\u4f8b\u5982\uff0c\u5979\u7684\u56e2\u961f\u9886\u5bfc\u5f00\u53d1\u4e86\u4e00\u79cd\u65b0\u578b\u7684\u751f\u7269\u8f93\u5165\/\u8f93\u51fa\uff08I \/ O\uff09\u8bbe\u5907\uff0c\u4ece\u800c\u4ece\u6839\u672c\u4e0a\u6539\u53d8\u4e86\u6211\u4eec\u4e0e\u751f\u7269\u8fdb\u884c\u4ea4\u4e92\u548c\u7f16\u7a0b\u7684\u65b9\u5f0f\u3002 \u5979\u7684\u56e2\u961f\u4f7f\u7528\u8fd9\u4e9b\u5de5\u5177\u6765\u63a8\u52a8\u7ec6\u80de\u7597\u6cd5\uff0c\u5929\u7136\u4ea7\u7269\u751f\u7269\u5408\u6210\u548c\u836f\u7269\u53d1\u73b0\u7b49\u4e0d\u540c\u9886\u57df\u7684\u53d8\u9769\u3002\u5979\u662f\u5341\u591a\u9879\u4e13\u5229\u7684\u53d1\u660e\u4eba\uff0c\u5979\u7684\u7814\u7a76\u8ba1\u5212\u5df2\u83b7\u5f97\u591a\u9879\u6b8a\u8363\uff0c\u5176\u4e2d\u5305\u62ec\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\uff08NIH\uff09\u4e3b\u4efb\u7684\u5148\u950b\u5956\uff0c\u4e16\u754c\u6280\u672f\u7f51\u7edc\uff08WTN\uff09\u751f\u7269\u6280\u672f\u5956\u548cTR35\u5956\u3002<\/span><\/p>\n<\/li>\n<\/ul>\n<p><span style=\"font-size: 15px\"><strong><em><span style=\"font-size: 15px\"><img class=\"\" style=\"width: 540px;height: 455px\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma8-1546606831.jpeg\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/span><\/em><\/strong><\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><em><span style=\"font-size: 15px\">Christopher A. Voigt (C.A.V)<\/span><\/em><\/strong><\/span><\/p>\n<ul class=\"list-paddingleft-2\" style=\"margin-left: 8px;margin-right: 8px\">\n<li>\n<p style=\"line-height: 1.75em\"><span style=\"font-size: 15px\">\u81ea2010\u5e74\u8d77\u4e00\u76f4\u62c5\u4efb\u7f8e\u56fd\u9a6c\u8428\u8bf8\u585e\u5dde\u5251\u6865\u5e02\u9ebb\u7701\u7406\u5de5\u5b66\u9662\uff08MIT\uff09\u751f\u7269\u5de5\u7a0b\u7cfb\u7684\u6559\u6388\uff0c\u5728\u90a3\u91cc\u4ed6\u662f\u5408\u6210\u751f\u7269\u5b66\u4e2d\u5fc3\u7684\u5171\u540c\u8d1f\u8d23\u4eba\u5e76\u6210\u7acb\u4e86MIT-Broad Foundry\u3002\u4ed6\u62c5\u4efb\u7f8e\u56fd\u5316\u5b66\u5b66\u4f1a\u671f\u520aACS Synthetic Biology\u7684\u4e3b\u7f16\u3002 \u5728\u9ebb\u7701\u7406\u5de5\u4e4b\u524d\uff0c\u4ed6\u5728\u7f8e\u56fd\u65e7\u91d1\u5c71\u52a0\u5229\u798f\u5c3c\u4e9a\u5927\u5b66\u836f\u7269\u5316\u5b66\u7cfb\u4efb\u6559\u3002<\/span><\/p>\n<\/li>\n<\/ul>\n<p><span style=\"font-size: 15px\"><strong><em><span style=\"font-size: 15px\"><img class=\"\" style=\"width: 540px;height: 359px\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma0-1546606831.jpeg\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/span><\/em><\/strong><\/span><\/p>\n<p><span style=\"font-size: 15px\"><strong><em><span style=\"font-size: 15px\">Ron Weiss (R.W.)<\/span><\/em><\/strong><\/span><\/p>\n<ul class=\"list-paddingleft-2\" style=\"margin-left: 8px;margin-right: 8px\">\n<li>\n<p style=\"line-height: 1.75em\"><span style=\"font-size: 15px\">\u7f8e\u56fd\u9ebb\u7701\u7406\u5de5\u5b66\u9662\uff08MIT\uff09\u751f\u7269\u5de5\u7a0b\u7cfb\u548c\u7535\u6c14\u5de5\u7a0b\u4e0e\u8ba1\u7b97\u673a\u79d1\u5b66\u7cfb\u7684\u6559\u6388\u3002\u4ed6\u521b\u7acb\u5e76\u62c5\u4efb\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u5408\u6210\u751f\u7269\u5b66\u4e2d\u5fc3\u4e3b\u4efb\u3002 \u4ed6\u4e8e2001\u5e74\u83b7\u5f97\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u535a\u58eb\u5b66\u4f4d\uff0c\u5e76\u4e8e2001\u5e74\u81f32009\u5e74\u5728\u7f8e\u56fd\u65b0\u6cfd\u897f\u5dde\u666e\u6797\u65af\u987f\u5927\u5b66\u4efb\u6559\u3002\u4ed6\u7684\u7814\u7a76\u5e2e\u52a9\u5f00\u62d3\u4e86\u5408\u6210\u751f\u7269\u5b66\u9886\u57df\uff0c\u901a\u8fc7\u8ba1\u7b97\u8bbe\u8ba1\uff0c\u6784\u5efa\u5e76\u5b9e\u9a8c\u6d4b\u8bd5\u4e86\u80fd\u591f\u8fdb\u884c\u6570\u5b57\u903b\u8f91\uff0c\u6a21\u62df\u63a7\u5236\u548c\u7ec6\u80de\u95f4\u901a\u4fe1\u7b49\u51e0\u4e2a\u57fa\u7840\u5408\u6210\u57fa\u56e0\u7535\u8def\u3002\u6700\u8fd1\uff0cWeiss\u5b9e\u9a8c\u5ba4\u8fd8\u4e13\u6ce8\u4e8e\u54fa\u4e73\u52a8\u7269\u5408\u6210\u751f\u7269\u5b66\uff0c\u91cd\u70b9\u662f\u6cbb\u7597\u5e94\u7528\u9886\u57df\uff0c\u5305\u62ec\u7ec4\u7ec7\u5de5\u7a0b\uff0c\u7cd6\u5c3f\u75c5\u548c\u764c\u75c7\u6cbb\u7597\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em\"><span style=\"font-size: 15px\"><\/span><\/p>\n<\/li>\n<\/ul>\n<p style=\"line-height: 1.75em\"><span style=\"font-size: 15px\"><\/span><\/p>\n<p style=\"line-height: 1.75em\"><span style=\"font-size: 15px\"><\/span><\/p>\n<\/p>\n<blockquote>\n<p style=\"margin-right: 8px;margin-left: 8px\"><span>\u6765\u6e90\uff1a\u518d\u521b |Regenesis<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px\"><span>\u7f16\u8bd1\uff1a\u5b5f\u51e1\u5eb7 \u7f57\u8bad\u8bad  \u5b5f\u51e1\u5eb7  \u5b59\u667a \u5f20\u76ca\u8c6a<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px\"><span>\u7f16\u8f91\uff1a\u738b\u6021\u853a<\/span><\/p>\n<\/blockquote>\n<p style=\"margin-right: 8px;margin-left: 8px\"><span><\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px\"><span><\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px\"><span><\/span><\/p>\n<section>\n<section>\n<section><strong><\/p>\n<p><span><strong>\u63a8\u8350\u9605\u8bfb<\/strong><\/span><\/p>\n<p><\/strong><\/section>\n<\/section>\n<\/section>\n<p><strong style=\"font-size: 14px;letter-spacing: 0.544px;text-decoration: underline\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><strong style=\"letter-spacing: 0.544px;line-height: 29.75px\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><strong style=\"letter-spacing: 0.544px;text-align: center;text-decoration: underline;font-size: 14px\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><strong style=\"letter-spacing: 0.544px;line-height: 29.75px\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247494777&amp;idx=1&amp;sn=f8371c9f275fb287736993ab2bb084c7&amp;chksm=e897b6f4dfe03fe2934ab2e862bef13bdaac7e2893d872a8979a7011e8c0b0f0198d48cd6e5e&amp;scene=21#wechat_redirect\" target=\"_blank\">Cell \u957f\u6587\u7efc\u8ff0\uff1a\u673a\u5668\u5b66\u4e60\u5982\u4f55\u52a9\u529b\u7f51\u7edc\u751f\u7269\u5b66<\/a><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/p>\n<p><strong style=\"font-size: 14px;letter-spacing: 0.544px;text-decoration: underline\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><strong style=\"letter-spacing: 0.544px;line-height: 29.75px\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><strong style=\"letter-spacing: 0.544px;text-align: center;text-decoration: underline;font-size: 14px\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><strong style=\"letter-spacing: 0.544px;line-height: 29.75px\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><strong style=\"letter-spacing: 0.544px;text-align: center;text-decoration: underline;font-size: 14px\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><strong style=\"letter-spacing: 0.544px;line-height: 29.75px\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247493535&amp;idx=1&amp;sn=c754d7e0df53ff7ee4f528a0f695325c&amp;chksm=e897bd12dfe03404d46a6f800fe086f426882da7cf40210cf9106088b96bab54aed05cc683f6&amp;scene=21#wechat_redirect\" target=\"_blank\">\u8d4b\u4e88\u4eba\u9020\u7ec6\u80de\u751f\u547d\uff0c\u5168\u4eba\u5de5\u7ec6\u80de\u5b9e\u73b0\u4e34\u8fd1<\/a><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/p>\n<p><strong style=\"font-size: 14px;letter-spacing: 0.544px;text-decoration: underline\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><strong style=\"letter-spacing: 0.544px;line-height: 29.75px\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247488049&amp;idx=1&amp;sn=b4acc1f0622104899f220fde1a06ccd3&amp;chksm=e89448bcdfe3c1aa26f88caf3692fba7f0d26f66da1a188b83ef95e0948f5701d6ccc1f841b3&amp;scene=21#wechat_redirect\" target=\"_blank\">\u4ece\u7ec6\u80de\u5230\u690d\u7269\u4eff\u751f\u673a\u5668\u4eba\u7684\u5386\u53f2\u6f14\u53d8<\/a><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/p>\n<p><strong style=\"font-size: 14px;letter-spacing: 0.544px;text-decoration: underline\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><strong style=\"letter-spacing: 0.544px;line-height: 29.75px\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><strong style=\"letter-spacing: 0.544px;text-align: center;text-decoration: underline;font-size: 14px\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><strong style=\"letter-spacing: 0.544px;line-height: 29.75px\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247494232&amp;idx=1&amp;sn=75cb83b613d5c1f4e05c25d70d2066bf&amp;chksm=e897b0d5dfe039c3f8548ad7aba485fc94f230a33f232ca8022e2f537f920ea3f2ae9c86b292&amp;scene=21#wechat_redirect\" target=\"_blank\">\u751f\u547d\u7b97\u6cd5\u590d\u6742\u5ea6\uff1a\u8fdb\u5316\u603b\u80fd\u627e\u5230\u4e00\u6761\u7b80\u5355\u8def\u5f84<\/a><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/p>\n<p><strong style=\"font-size: 14px;letter-spacing: 0.544px;text-decoration: underline\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><strong style=\"letter-spacing: 0.544px;line-height: 29.75px\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247492586&amp;idx=1&amp;sn=db15b8d87dbaf5abc15993b6ad78bcea&amp;chksm=e897b967dfe030718b17e0088378a7e6007886cca4510855db86829d26bc6d5001170c8e93df&amp;scene=21#wechat_redirect\" target=\"_blank\">\u57fa\u56e0\u4e4b\u95f4\u7684\u91cd\u590d\u535a\u5f08\u5982\u4f55\u5f71\u54cd\u751f\u7269\u8fdb\u5316\uff1f<\/a><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/p>\n<p><strong style=\"font-size: 14px;letter-spacing: 0.544px;text-decoration: underline\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><strong style=\"letter-spacing: 0.544px;line-height: 29.75px\"><strong style=\"font-size: 17px;letter-spacing: 0.544px\"><span style=\"font-size: 14px\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247493835&amp;idx=1&amp;sn=79d5757eb3a6bdfb0988b4c3cd7a6a51&amp;chksm=e897b246dfe03b50215401742794c67eb09fc8affb2ae4abd6fa981400fab59f821c76889f9b&amp;scene=21#wechat_redirect\" target=\"_blank\">\u5bbf\u4e3b\u4e0e\u5fae\u751f\u7269\u4e00\u8d77\u6784\u6210\u201c\u8d85\u7ea7\u751f\u7269\u4f53\u201d\u5982\u4f55\u6f14\u5316\uff1f<\/a><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/p>\n<p><strong><strong><strong><span><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247487778&amp;idx=1&amp;sn=c2e77ec93213c4c63f57a777ff10e368&amp;chksm=e8944bafdfe3c2b9d66544dafe7403159473e8c94fd3bc513f5300c353bcec49c0c0b69797af&amp;scene=21#wechat_redirect\" target=\"_blank\">\u52a0\u5165\u96c6\u667a\uff0c\u4e00\u8d77\u590d\u6742\uff01<\/a><\/span><\/strong><\/strong><\/strong><\/p>\n<section class=\"\">\n<p style=\"text-align: center\">\n<section class=\"mpa-template\">\n<section class=\"\">\n<section class=\"\">\n<p style=\"min-height: 1em\">\n<hr \/>\n<div class=\"post-image\"><img class=\"__bg_gif\" width=\"100%\" style=\"letter-spacing: 0.5px;width: 64px !important\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma6-1546606832.gif\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/div>\n<p style=\"min-height: 1em\">\n<section>\n<section style=\"margin-right: 0.5em;margin-left: 0.5em;line-height: 25.6px;text-align: center\">\n<section style=\"margin-right: 0.5em;margin-left: 0.5em;line-height: 25.6px\">\n<section>\n<section style=\"margin-right: 0.5em;margin-left: 0.5em;font-size: 15px\">\n<section>\n<p><strong><span>\u96c6\u667a\u4ff1\u4e50\u90e8QQ\u7fa4\uff5c877391004<\/span><\/strong><\/p>\n<p><strong><span>\u5546\u52a1\u5408\u4f5c\u53ca\u6295\u7a3f\u8f6c\u8f7d\uff5cswarma@swarma.org<\/span><\/strong><\/p>\n<section style=\"margin-right: 0.5em;margin-left: 0.5em\">\n<h1 style=\"margin-top: 10px;margin-bottom: 10px;line-height: 1.75em\"><strong><strong><span><span>\u25c6<\/span><span>\u25c6<\/span><span>\u25c6<\/span><\/span><\/strong><\/strong><\/h1>\n<\/section>\n<p><span><strong><span style=\"font-size: 14px\">\u641c\u7d22\u516c\u4f17\u53f7\uff1a\u96c6\u667a\u4ff1\u4e50\u90e8<\/span><\/strong><\/span><\/p>\n<\/p>\n<p><span><strong><span style=\"font-size: 14px\">\u52a0\u5165\u201c\u6ca1\u6709\u56f4\u5899\u7684\u7814\u7a76\u6240\u201d<\/span><\/strong><\/span><\/p>\n<section>\n<div class=\"post-image\"><img class=\"\" style=\"width: 156px !important\" src=\"http:\/\/swarma.org\/wp-content\/uploads\/2019\/01\/swarma5-1546606832.jpg\" alt=\"\u96c6\u667a\" title=\"\u96c6\u667a\" \/><\/div>\n<\/section>\n<p style=\"min-height: 1em\"><span style=\"font-size: 14px\">\u8ba9\u82f9\u679c\u7838\u5f97\u66f4\u731b\u70c8\u4e9b\u5427\uff01<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<blockquote class=\"keep-source\">\n<p>\u539f\u6587\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff08\u96c6\u667a\u4ff1\u4e50\u90e8\uff09\uff1a<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?timestamp=1546606825&amp;src=3&amp;ver=1&amp;signature=BOrz5SKCLoPtrZYc2VnOOKLxR9LuQG3EHFEGti46LmJZxxDkLet2rtHYXufOTFamRzQtXfGDTOsF509UOZG2nyz5RRxCJQGP-xZpFVkoYakt5XrEQmItAg7FhxNSkidzW94F0PIVQ6jrSdtDLr8l42cSblCdhWuQe7cIm35p8hg=\">\u96c6\u667a<\/a><\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5bfc\u8bed \u4f5c\u4e3a\u4e00\u4e2a\u8de8\u5b66\u79d1\u7684\u65b0\u5174\u9886\u57df\uff0c\u5408\u6210\u751f\u7269\u5b66\uff08synthetic biology\uff09\u8bd5\u56fe\u4ece\u5de5\u7a0b\u89d2\u5ea6\u7406\u89e3\u548c\u6784\u5efa\u751f\u547d\u7684\u590d\u6742\u6027\uff0c\u4e5f\u5728\u4e3a\u751f\u7269\u533b\u7597\u3001\u751f\u7269\u6280\u672f\u548c\u57fa\u7840\u5206\u5b50\u7814\u7a76\u6301\u7eed\u6ce8\u5165\u52a8\u529b\u3002 Nature \u6742\u5fd7\u66fe\u57282014\u5e74\u5bf9\u5408\u6210\u751f\u7269\u5b66\u9886\u57df5\u4f4d\u9876\u5c16\u79d1\u5b66\u5bb6\u8fdb\u884c\u8fc7\u4e00\u6b21\u8bbf\u8c08\uff0c\u4ed6\u4eec\u5c31\u5408\u6210\u751f\u7269\u5b66\u7684\u672a\u6765\uff0c\u5408\u6210\u751f\u7269\u5b66\u5728\u57fa\u7840\u548c\u5e94\u7528\u79d1\u5b66&#8230;<\/p>\n","protected":false},"author":1,"featured_media":14185,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[17],"tags":[],"special":[],"_links":{"self":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/14181"}],"collection":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=14181"}],"version-history":[{"count":0,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/14181\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/media\/14185"}],"wp:attachment":[{"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=14181"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=14181"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=14181"},{"taxonomy":"special","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fspecial&post=14181"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}