{"id":19584,"date":"2020-05-09T17:18:32","date_gmt":"2020-05-09T09:18:32","guid":{"rendered":"https:\/\/swarma.org\/?p=19584"},"modified":"2020-05-09T17:18:32","modified_gmt":"2020-05-09T09:18:32","slug":"nature%ef%bc%9a%e6%9e%84%e5%bb%ba%e6%96%b0%e5%86%a0%e8%82%ba%e7%82%8e%e8%9b%8b%e7%99%bd%e8%b4%a8%e7%9b%b8%e4%ba%92%e4%bd%9c%e7%94%a8%e7%bd%91%e7%bb%9c%ef%bc%8c%e6%bd%9c%e5%9c%a8%e7%89%b9%e6%95%88","status":"publish","type":"post","link":"https:\/\/swarma.org\/?p=19584","title":{"rendered":"Nature\uff1a\u6784\u5efa\u65b0\u51a0\u80ba\u708e\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\uff0c\u6f5c\u5728\u7279\u6548\u836f\u7f29\u5c0f\u81f369\u79cd"},"content":{"rendered":"
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\u75c5\u6bd2\u5982\u4f55\u52ab\u6301\u7ec6\u80de\u7cfb\u7edf\u662f\u4e00\u4e2a\u91cd\u8981\u7684\u7ec6\u80de\u751f\u7269\u5b66\u95ee\u9898\u3002\u8fd1\u671f\u7684Nature\u671f\u520a\u53d1\u8868\u4e86\u4e00\u7bc7\u7531125\u4f4d\u5b66\u8005\u5408\u4f5c\u7684\u8bba\u6587\uff0c\u63a2\u7a76\u4e86\u65b0\u51a0\u75c5\u6bd2\u5728\u611f\u67d3\u8fc7\u7a0b\u4e2d\u5982\u4f55\u4e0e\u4eba\u4f53\u7ec6\u80de\u4e2d\u7684\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u3002\u7814\u7a76\u8005\u6210\u529f\u7ed8\u5236\u51fa\u4e86\u75c5\u6bd2\u86cb\u767d\u4e0e\u4eba\u4f53\u86cb\u767d\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\u3002\u5e76\u6839\u636e\u8be5\u7f51\u7edc\uff0c\u8bba\u6587\u7ed9\u51fa\u4e86\u6cbb\u7597\u65b0\u51a0\u7684\u5019\u9009\u836f\u7269\u5217\u8868\uff0c\u5176\u4e2d\u4e00\u4e9b\u6b63\u5728\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
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\u8bba\u6587\u9898\u76ee\uff1a<\/span><\/section>\n
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing<\/span><\/section>\n
\u8bba\u6587\u5730\u5740\uff1a<\/span><\/section>\n
https:\/\/www.nature.com\/articles\/s41586-020-2286-9#Sec36<\/span><\/section>\n<\/section>\n<\/section>\n<\/blockquote>\n


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\u836f\u7269\u672c\u8d28\u4e0a\u662f\u67d0\u79cd\u5316\u5b66\u7269\u8d28\uff0c\u901a\u5e38\u4f5c\u7528\u4e8e\u4eba\u4f53\u5185\u7684\u86cb\u767d\u8d28\uff08\u836f\u7269\u9776\u70b9\uff09\u4ea7\u751f\u6cbb\u7597\u6548\u679c\u3002<\/span><\/p>\n


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\u5728\u4eba\u4f53\u5185\u5343\u5343\u4e07\u4e07\u7684\u86cb\u767d\u8d28\u4e2d\uff0c\u54ea\u4e9b\u662f\u9700\u8981\u836f\u7269\u5e72\u9884\u7684\u5462\uff1f\u8fd9\u5c31\u9700\u8981\u627e\u51fa\u4e0e\u75be\u75c5\u76f8\u5173\u7684\u86cb\u767d\u8d28\uff0c\u8fdb\u800c\u201c\u5bf9\u75c7\u4e0b\u836f\u201d\u3002<\/strong><\/span><\/p>\n


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\u4e3a\u4e86\u627e\u5230\u4e0e\u65b0\u51a0\u80ba\u708e\u76f8\u5173\u7684\u4eba\u4f53\u86cb\u767d\u8d28\uff0c\u7f8e\u56fd\u52a0\u5dde\u5927\u5b66\u65e7\u91d1\u5c71\u5206\u6821\u9886\u8854\u7684\u5168\u7403\u79d1\u7814\u56e2\u961f\u5171125\u4f4d\u5b66\u8005\u901a\u529b\u5408\u4f5c\uff0c\u53d1\u8868\u4e86\u8fd9\u7bc7\u300a\u65b0\u51a0\u75c5\u6bd2\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\u63ed\u793a\u836f\u7269\u518d\u5229\u7528\u7684\u9776\u70b9\u300b\uff0c\u5176\u4e3b\u8981\u7814\u7a76\u5305\u62ec\uff1a<\/span><\/p>\n

    1. \u7ed8\u5236\u4e86\u75c5\u6bd2\u86cb\u767d\u4e0e\u4eba\u4f53\u86cb\u767d\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc<\/span><\/p>\n

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    3. \u7b5b\u9009\u4e86\u5e72\u9884\u86cb\u767d\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\u7684\u73b0\u6709\u836f\u7269<\/span><\/p>\n

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\u672c\u7814\u7a76\u53d1\u8868\u5728Nature\u6742\u5fd7\u4e4b\u524d\uff0c\u5df2\u7ecf\u4e8e3\u6708\u4efd\u516c\u5e03\u4e86\u9884\u5370\u672c\uff0c\u6240\u4ee5\u5176\u7814\u7a76\u7ed3\u679c\u5df2\u88ab\u4e00\u4e9b\u540e\u7eed\u7814\u7a76\u4f5c\u4e3a\u57fa\u7840\u6765\u4f7f\u7528\u3002\u4f8b\u5982 Albert-L\u00e1szl\u00f3 Barab\u00e1si \u56e2\u961f4\u6708\u53d1\u8868\u7684\u4e00\u7bc7\u9884\u5370\u672c\u8bba\u6587\uff0c\u5c31\u5229\u7528\u8fd9\u7bc7Nature\u7814\u7a76\u63d0\u4f9b\u7684\u6570\u636e\uff0c\u5c06\u65b0\u51a0\u80ba\u708e\u7279\u6548\u836f\u7684\u641c\u7d22\u8303\u56f4\u7f29\u5c0f\u5230\u4e8681\u79cd\u3002<\/span><\/p>\n


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Barab\u00e1si\u7ec4\u6700\u65b0\uff1a\u7f51\u7edc\u79d1\u5b66\u5927\u5e45\u7f29\u5c0f\u65b0\u51a0\u7279\u6548\u836f\u641c\u7d22\u8303\u56f4\u81f381\u79cd<\/a><\/span><\/p>\n

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\u8bba\u6587\u9996\u6b21\u7cfb\u7edf\u5730\u5206\u6790\u4e86\u65b0\u51a0\u75c5\u6bd2\u86cb\u767d\u4e0e\u4eba\u4f53\u86cb\u767d\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u5173\u7cfb\u3002\u8fd9\u4e9b\u76f8\u4e92\u4f5c\u7528\u662f\u5982\u4f55\u627e\u5230\u7684\u5462\uff1f<\/strong><\/span><\/section>\n

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\u9996\u5148\uff0c\u4ece\u75c5\u6bd2\u51fa\u53d1\uff0c\u514b\u9686\u65b0\u51a0\u75c5\u6bd2\u57fa\u56e0<\/strong>\uff0c\u5e76\u5c06\u57fa\u56e0\u5bfc\u5165\u5230\u4eba\u4f53\u7ec6\u80de\u4e2d\u3002\u75c5\u6bd2\u57fa\u56e0\u5728\u4eba\u4f53\u7ec6\u80de\u4e2d\u8868\u8fbe\u5f62\u621027\u79cd\u75c5\u6bd2\u86cb\u767d<\/strong>\u3002<\/span><\/section>\n

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\u7136\u540e\uff0c\u4ee5\u8fd92\u79cd\u4e2a\u75c5\u6bd2\u86cb\u767d<\/strong>\u4f5c\u4e3a\u201c\u8bf1\u9975\u201d\uff0c\u627e\u5230\u548c\u5b83\u4eec\u7d27\u5bc6\u7ed3\u5408\u7684\u4eba\u4f53\u86cb\u767d<\/strong>\uff08\u7ed3\u5408\u4e0d\u7d27\u5bc6\u7684\u86cb\u767d\u4f1a\u5728\u7eaf\u5316\u8fc7\u7a0b\u4e2d\u81ea\u52a8\u8131\u79bb\uff09\u3002\u5b9e\u9a8c\u53d1\u73b0\u4e86332\u4e2a<\/strong>\u9ad8\u7f6e\u4fe1\u5ea6\u7684\u75c5\u6bd2\u86cb\u767d-\u4eba\u4f53\u86cb\u767d\u76f8\u4e92\u4f5c\u7528\uff0c\u5e76\u636e\u6b64\u7ed8\u5236\u51fa\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528 (Protein-protein interaction, PPI) \u7f51\u7edc<\/strong>\u3002<\/span><\/section>\n

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\u4e0b\u56fe\u603b\u7ed3\u4e86\u4e0a\u8ff0\u5b9e\u9a8c\u7684\u6d41\u7a0b<\/span>       <\/span><\/section>\n

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1. \u57fa\u56e0\u672c\u4f53\u5bcc\u96c6\u5206\u6790\uff08Gene ontology enrichment analysis\uff09\uff1a332\u4e2a\u65b0\u51a0\u76f8\u5173\u4eba\u4f53\u86cb\u767d\u6d89\u53ca\u591a\u79cd\u7ec6\u80de\u8fc7\u7a0b\uff0c\u5305\u62ec\u86cb\u767d\u8d28\u8f6c\u5f55\u3001\u7ffb\u8bd1\u3001\u6cdb\u7d20\u5316\u8c03\u8282\u3001\u5165\u6838\u8f6c\u8fd0\u548c\u7ebf\u7c92\u4f53\u529f\u80fd\u3002<\/strong><\/span><\/p>\n

2. \u7ec4\u7ec7\u7ec6\u80de\u4e2d\u8868\u8fbe\u91cf\u5206\u6790\uff1a\u572829\u79cd\u4eba\u4f53\u7ec4\u7ec7\u4e2d\uff0c\u65b0\u51a0\u76f8\u5173\u4eba\u4f53\u86cb\u767d\u5728\u80ba\u90e8\u7ec4\u7ec7\u8868\u8fbe\u91cf\u6700\u9ad8<\/strong>\u3002\u8fd9\u652f\u6301\u4e86\u65b0\u51a0\u75c5\u6bd2\u4f18\u5148\u5165\u4fb5\u80ba\u90e8\u7ec4\u7ec7\u7684\u5047\u8bbe\u3002<\/span><\/p>\n

3. \u5bf9\u4e8e\u75c5\u6bd2\u611f\u67d3\u7684\u54cd\u5e94\uff1a\u5728\u611f\u67d3\u8fc7\u7a0b\u4e2d\uff0c\u75c5\u6bd2\u86cb\u767d-\u4eba\u4f53\u86cb\u767d\u76f8\u4e92\u4f5c\u7528\u5bf9\u7684\u4e30\u5ea6\u76f8\u5173\u6027\u9ad8<\/strong>\u3002\u8fd9\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u4e86\u76f8\u4e92\u4f5c\u7528\u7684\u53ef\u4fe1\u5ea6\u3002<\/span><\/p>\n

4. \u5bf9\u6bd4\u5176\u4ed6\u75c5\u539f\u4f53\u7f51\u7edc\uff1a\u5728\u6240\u6bd4\u8f83\u768410\u79cd\u75c5\u539f\u4f53\u4e2d\uff0c\u897f\u5c3c\u7f57\u6cb3\u75c5\u6bd2 (WNV) \u548c\u7ed3\u6838\u5206\u679d\u6746\u83cc (Mtb) <\/strong>\u6240\u5f62\u6210\u7684\u75c5\u6bd2-\u4eba\u4f53\u86cb\u767d\u7f51\u7edc\u548c\u65b0\u51a0\u75c5\u6bd2\u7684\u7f51\u7edc\u6700\u76f8\u4f3c\u3002<\/span><\/p>\n


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\u836f\u7269\u901a\u8fc7\u4f5c\u7528\u4e8e\u4eba\u4f53\u5185\u7684\u86cb\u767d\u8d28\uff08\u836f\u7269\u9776\u70b9\uff09\u6765\u4ea7\u751f\u6cbb\u7597\u6548\u679c\u3002\u5728\u73b0\u6709\u836f\u7269\u4e2d\uff0c\u6709\u54ea\u4e9b\u53ef\u4ee5\u5e72\u9884\u65b0\u51a0\u76f8\u5173\u7684\u4eba\u4f53\u86cb\u767d\u8d28\u5462\uff1f<\/strong><\/span><\/section>\n

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\u6587\u7ae0\u641c\u5bfb\u4e86\u5316\u5b66\u6570\u636e\u5e93\u3001\u836f\u7406\u5b66\u6307\u5357\u7b49\u6750\u6599\u4e2d\u7684\u4e0a\u4e07\u79cd\u5df2\u77e5\u5316\u5408\u7269\uff0c\u67e5\u770b\u8fd9\u4e9b\u5316\u5408\u7269\u7684\u9776\u70b9\u662f\u5426\u843d\u5728\u65b0\u51a0\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\u4e0a\u3002<\/strong><\/span><\/section>\n

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\u7814\u7a76\u53d1\u73b0\u4e8669\u4e2a\u7b26\u5408\u4e0a\u8ff0\u6761\u4ef6\u7684\u5df2\u77e5\u5316\u5408\u7269\uff0c<\/strong>\u5176\u4e2d\u5305\u62ec29\u4e2a\u83b7\u7f8e\u56fdFDA\uff08\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff09\u6279\u51c6\u7684\u836f\u7269\uff0c12\u4e2a\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u7684\u836f\u7269\uff0c\u4ee5\u53ca28\u4e2a\u4e34\u5e8a\u524d\u5316\u5408\u7269\u3002           <\/span><\/section>\n
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\u56fe4\uff1a\u75c5\u6bd2\u86cb\u767d-\u4eba\u4f53\u86cb\u767d\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\u3002\u7ea2\u8272\u4e3a\u75c5\u6bd2\u86cb\u767d\uff0c\u7070\u8272\u4e3a\u4eba\u4f53\u86cb\u767d\uff0c\u6a59\u8272\u4e3a\u836f\u7269\u9776\u70b9<\/span><\/strong><\/span><\/section>\n


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\u7b5b\u9009\u51fa\u7684\u5316\u5408\u7269\u662f\u5426\u6709\u6548\u5462\uff1f<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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\u7814\u7a76\u56e2\u961f\u76ee\u524d\u5df2\u5bf9\u5217\u8868\u4e2d\u768447\u4e2a\u5316\u5408\u7269\u8fdb\u884c\u4e86\u751f\u7269\u6d4b\u8bd5\uff08\u4f53\u5916\uff09\uff0c\u5e76\u6b63\u5728\u6d4b\u8bd5\u5176\u4f59\u5316\u5408\u7269\u3002\u5728\u6d4b\u8bd5\u4e2d\uff0c\u9996\u5148\u5c06\u836f\u7269\u6dfb\u52a0\u5230\u7ec6\u80de\uff0c\u7136\u540e\u7528\u75c5\u6bd2\u611f\u67d3\u7ec6\u80de\uff0c\u89c2\u5bdf\u836f\u7269\u7684\u6297\u75c5\u6bd2\u6d3b\u6027\u3002\u5230\u76ee\u524d\u4e3a\u6b62\uff0c\u5df2\u670910\u79cd\u836f\u7269\u663e\u793a\u51fa\u6297\u75c5\u6bd2\u4f5c\u7528\u3002<\/strong>\u8fd9\u4e9b\u836f\u7269\u5206\u4e3a\u4e24\u7c7b\uff1a<\/span><\/section>\n

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1. \u86cb\u767d\u8d28\u7ffb\u8bd1\u6291\u5236\u5242<\/strong>\uff1azotatifin\u548cTernatin-4\uff0c\u4e34\u5e8a\u7528\u4e8e\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u3002\u8fd9\u4e24\u79cd\u836f\u7269\u7684\u5236\u9020\u5546\u90fd\u5ba3\u5e03\u5c06\u5f00\u59cb\u65b0\u51a0\u75c5\u6bd2\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/span><\/p>\n

2. Sigma\u53d7\u4f53\u8c03\u8282\u5242<\/strong>\uff1a\u6297\u7ec4\u80fa\u836f (cloperastine\u548cclemastine)\u3001\u6297\u7cbe\u795e\u75c5\u836f (haloperidol\u548cmelperone)\u3001\u6297\u759f\u836f (hydroxychloroquine)\u3001\u6fc0\u7d20 (progesterone)\u3001\u6297\u7126\u8651\u836f (siramesine)\uff0c\u4ee5\u53ca1\u79cd\u4e34\u5e8a\u524d\u5316\u5408\u7269\u3002<\/span><\/p>\n


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\u8bba\u6587\u4ee5\u751f\u7269\u5b66\u4e3a\u5bfc\u5411\u6784\u5efa\u4e86\u65b0\u51a0\u75c5\u6bd2\u86cb\u767d-\u4eba\u7c7b\u86cb\u767d\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\u3002\u8fdb\u800c\u901a\u8fc7\u7f51\u7edc\u4e2d\u7684\u9776\u70b9\u7b5b\u9009\u5019\u9009\u836f\u7269\u3002\u6574\u7bc7\u6587\u7ae0\u5efa\u7acb\u5728\u5927\u91cf\u751f\u7269\u5b9e\u9a8c\u7ed3\u679c\u4e0a\uff0c\u8bf4\u670d\u529b\u5f3a\u3002<\/span><\/p>\n


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\u53ef\u4ee5\u9884\u89c1\uff0c\u540e\u7eed\u4f1a\u6709\u5927\u91cf\u7f51\u7edc\u533b\u5b66\u3001\u7cfb\u7edf\u751f\u7269\u5b66\u3001\u8ba1\u7b97\u751f\u7269\u5b66\u7b49\u9886\u57df\u7684\u7814\u7a76\u57fa\u4e8e\u6b64\u7bc7\u8bba\u6587\u3002\u201c332\u4e2a\u75c5\u6bd2\u86cb\u767d-\u4eba\u4f53\u86cb\u767d\u76f8\u4e92\u4f5c\u7528\u201d\uff0c\u201c69\u4e2a\u5019\u9009\u836f\u7269\u201d\uff0c\u6216\u8bb8\u4f1a\u6210\u4e3a\u5b66\u8005\u5e38\u5907\u7684\u6570\u636e\u96c6\u3002<\/span><\/p>\n


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\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/strong><\/span><\/p>\n

\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\u7ecf\u5178\u6587\u732e\uff1a<\/span><\/p>\n

Rual J F, Venkatesan K, Hao T, et al. Towards a proteome-scale map of the human protein\u2013protein interaction network[J]. Nature, 2005, 437(7062): 1173-1178.<\/span><\/p>\n

Stelzl U, Worm U, Lalowski M, et al. A human protein-protein interaction network: a resource for annotating the proteome[J]. Cell, 2005, 122(6): 957-968.<\/span><\/p>\n

\u5176\u4ed6\u62a5\u9053\uff1a<\/span><\/p>\n

https:\/\/www.genengnews.com\/insights\/sars-cov-2-protein-interaction-map-reveals-drug-targets\/<\/span><\/p>\n

https:\/\/prelights.biologists.com\/highlights\/a-sars-cov-2-human-protein-protein-interaction-map-reveals-drug-targets-and-potential-drug-repurposing\/<\/span><\/p>\n

PPI\u7f51\u7edc\u53ef\u89c6\u5316\uff1a<\/span><\/p>\n

https:\/\/ppi.zoiclabs.io\/#\/<\/span><\/p>\n


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\u4ee5\u4e0a\u662f\u5bf9\u8fd9\u7bc7Nature\u7814\u7a76\u8981\u70b9\u7684\u4ecb\u7ecd\u3002\u66f4\u591a\u6570\u636e\u5206\u6790\u5de5\u4f5c\u3001\u7814\u7a76\u65b9\u6cd5\u4ecb\u7ecd\uff0c\u8bf7\u53c2\u89c1\u8bba\u6587\u539f\u6587\u3002<\/span><\/section>\n

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\u5982\u679c\u4f60\u5177\u5907\u76f8\u5173\u4e13\u4e1a\u80cc\u666f\uff0c\u613f\u610f\u5e2e\u52a9\u5927\u5bb6\u6df1\u5ea6\u89e3\u8bfb\u8fd9\u7bc7\u8bba\u6587\uff0c\u8bf7\u626b\u7801\u62a5\u540d\u300c\u6211\u8981\u8bb2\u300d<\/span><\/strong>\uff0c\u6211\u4eec\u5c06\u534f\u52a9\u4f60\u5c55\u5f00\u4e00\u6b211\u5c0f\u65f6\u7684\u7ebf\u4e0a\u89e3\u8bfb\u6d3b\u52a8\uff0c\u5e76\u5728\u96c6\u667a\u5e73\u53f0\u516c\u5f00\u76f4\u64ad\u3002<\/span><\/section>\n

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<\/span><\/strong><\/span><\/strong>\u5982\u679c\u4f60\u5bf9\u8fd9\u9879\u7814\u7a76\u611f\u5174\u8da3\uff0c\u5e0c\u671b\u53c2\u4e0e\u7ebf\u4e0a\u89e3\u8bfb\u6d3b\u52a8\uff0c\u4e0e\u66f4\u591a\u4eba\u4ea4\u6d41\u8bba\u6587\uff0c\u8bf7\u626b\u7801\u62a5\u540d\u300c\u6211\u8981\u542c\u300d<\/span><\/strong>\uff0c\u4e3a\u8fd9\u7bc7\u8bba\u6587\u79ef\u6512\u4eba\u6c14\u3002<\/span><\/span><\/section>\n

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\u626b\u7801\u767b\u5f55\u96c6\u667a\u6591\u56fe\u62a5\u540d\u300c\u6211\u8981\u542c\u300d\u6216\u300c\u6211\u8981\u8bb2\u300d\u3002\u96c6\u667a\u6591\u56fe\u662f\u7531\u96c6\u667a\u4ff1\u4e50\u90e8\u53d1\u8d77\u3001\u4ee5\u590d\u6742\u6027\u79d1\u5b66\u4e3a\u4e3b\u9898\u7684\u81ea\u7ec4\u7ec7\u5b66\u4e60\u793e\u533a\uff0c\u627f\u8f7d\u4e86\u96c6\u667a\u4ff1\u4e50\u90e8\u7684\u8bba\u6587\u89e3\u8bfb\u6d3b\u52a8\u3002<\/strong><\/p>\n

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Nature\u6700\u65b0\uff1a\u4eba\u53e3\u6d41\u52a8\u53ef\u9884\u6d4b\u75ab\u60c5\u4f20\u64ad\uff0c\u5e76\u63ed\u793a\u6211\u56fd\u786e\u8bca\u6570\u636e\u771f\u5b9e\u53ef\u9760<\/strong><\/span><\/a>
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\u5251\u6865\u5927\u5b66\u6700\u65b0\u7814\u7a76\uff1a\u57fa\u56e0\u7f51\u7edc\u5206\u6790\u63ed\u793a\u5317\u7f8e\u3001\u4e2d\u56fd\u3001\u6b27\u6d32\u7684\u65b0\u51a0\u75c5\u6bd2\u5dee\u5f02<\/strong><\/span><\/a>
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Nature\u547c\u5401\uff1a\u5e94\u5bf921\u4e16\u7eaa\u7684\u5927\u89c4\u6a21\u6d41\u884c\u75c5\uff0c\u5404\u4e2a\u5b66\u79d1\u5fc5\u987b\u8054\u5408\u8d77\u6765<\/strong><\/span><\/a>
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\u5546\u52a1\u5408\u4f5c\u53ca\u6295\u7a3f\u8f6c\u8f7d\uff5cswarma@swarma.org
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\u25c6 <\/span>\u25c6 <\/span>\u25c6<\/span><\/span><\/strong><\/strong><\/h1>\n<\/section>\n

\u641c\u7d22\u516c\u4f17\u53f7\uff1a\u96c6\u667a\u4ff1\u4e50\u90e8<\/span><\/strong><\/span><\/p>\n


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\u52a0\u5165\u201c\u6ca1\u6709\u56f4\u5899\u7684\u7814\u7a76\u6240\u201d<\/span><\/strong><\/span><\/p>\n

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\u8ba9\u82f9\u679c\u7838\u5f97\u66f4\u731b\u70c8\u4e9b\u5427\uff01<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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\ud83d\udc47\u70b9\u51fb\u201c\u9605\u8bfb\u539f\u6587\u201d\uff0c\u4e86\u89e3\u66f4\u591a\u8bba\u6587\u4fe1\u606f<\/span><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

\u5bfc\u8bed \u75c5\u6bd2\u5982\u4f55\u52ab\u6301\u7ec6\u80de\u7cfb\u7edf\u662f\u4e00\u4e2a\u91cd\u8981\u7684\u7ec6\u80de\u751f\u7269\u5b66\u95ee\u9898\u3002\u8fd1\u671f\u7684Nature\u671f\u520a\u53d1\u8868\u4e86\u4e00\u7bc7\u7531125\u4f4d\u5b66\u8005\u5408\u4f5c\u7684\u8bba\u6587\uff0c\u63a2\u7a76\u4e86\u65b0\u51a0\u75c5\u6bd2\u5728\u611f\u67d3\u8fc7\u7a0b\u4e2d\u5982\u4f55\u4e0e\u4eba\u4f53\u7ec6\u80de\u4e2d\u7684\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u3002\u7814\u7a76\u8005\u6210\u529f\u7ed8\u5236\u51fa\u4e86\u75c5\u6bd2\u86cb\u767d\u4e0e\u4eba\u4f53\u86cb\u767d\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\u3002\u5e76\u6839\u636e\u8be5\u7f51\u7edc\uff0c\u8bba\u6587\u7ed9\u51fa\u4e86\u6cbb\u7597\u65b0\u51a0\u7684\u5019\u9009\u836f\u7269\u5217\u8868\uff0c\u5176\u4e2d\u4e00\u4e9b\u6b63\u5728\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\u3002 &…<\/p>\n","protected":false},"author":1,"featured_media":19576,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"special":[],"_links":{"self":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/19584"}],"collection":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=19584"}],"version-history":[{"count":0,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/19584\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/media\/19576"}],"wp:attachment":[{"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=19584"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=19584"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=19584"},{"taxonomy":"special","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fspecial&post=19584"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}