{"id":26337,"date":"2021-05-16T22:31:57","date_gmt":"2021-05-16T14:31:57","guid":{"rendered":"https:\/\/swarma.org\/?p=26337"},"modified":"2021-05-19T11:17:14","modified_gmt":"2021-05-19T03:17:14","slug":"%e5%a4%9a%e5%ad%a6%e7%a7%91%e7%a0%94%e7%a9%b6%e7%9a%84%e4%b8%89%e7%a7%8d%e5%bd%a2%e6%80%81","status":"publish","type":"post","link":"https:\/\/swarma.org\/?p=26337","title":{"rendered":"\u591a\u5b66\u79d1\u7814\u7a76\u7684\u4e09\u79cd\u5f62\u6001"},"content":{"rendered":"
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\u968f\u7740\u5316\u5b66\u7684\u53d1\u5c55\uff0c\u5c24\u5176\u662f19\u4e16\u7eaa\u521d\u671f\u5316\u5b66\u7684\u4e00\u4e2a\u5206\u652f\u5b66\u79d1\u2014\u2014\u6709\u673a\u5316\u5b66\u5728\u6b27\u6d32\u7684\u5f62\u6210\uff0c\u7814\u7a76\u8005\u5f00\u59cb\u628a\u5316\u5b66\u4e0e\u751f\u7269\u5b66\u6574\u5408\u5728\u4e00\u8d77\uff0c\u5982\u5f53\u65f6\u7684\u5fb7\u56fd\u5df2\u7ecf\u51fa\u73b0\u4e86\u300a\u751f\u7406\u5316\u5b66\u6742\u5fd7\u300b<\/span>\uff08Zeitschrift fur Physiologische Chemie\uff09<\/span>\u8fd9\u6837\u660e\u663e\u5177\u6709\u4ea4\u53c9\u5b66\u79d1\u8272\u5f69\u7684\u79d1\u5b66\u671f\u520a\u30021905\u5e74\u7684\u7f8e\u56fd\u4e5f\u8bde\u751f\u4e86\u4e00\u672c\u76f8\u4f3c\u7684\u671f\u520a\u2014\u2014\u300a\u751f\u7269\u5316\u5b66\u6742\u5fd7\u300b<\/span>\uff08Journal of Biological Chemistry\uff09<\/span>\uff1b\u5728\u8be5\u6742\u5fd7\u7684\u7b2c\u4e00\u5c4a\u7f16\u59d4\u4f1a\u6210\u5458\u4e2d\uff0c\u4e00\u4f4d\u6765\u81ea\u4f2f\u514b\u5229\u5927\u5b66\u7684\u79d1\u5b66\u5bb6\u5a04\u4f2f<\/span>\uff08Loeb J\uff09<\/span>\u5728\u7ed9\u4e3b\u7f16\u7684\u4fe1\u4e2d\u8868\u8fbe\u4e86\u4ed6\u5bf9\u5b66\u79d1\u4ea4\u53c9\u7684\u4fe1\u5ff5\uff1a\u201c\u751f\u7269\u5b66\u7684\u672a\u6765\u5efa\u7acb\u5728\u4ece\u5316\u5b66\u7684\u89d2\u5ea6\u6765\u7814\u7a76\u751f\u7269\u5b66\u95ee\u9898\u201d[1]\u3002<\/span><\/p>\n

\u8fd9\u79cd\u4ea4\u53c9\u5b66\u79d1\u9996\u5148\u4f53\u73b0\u5728\u5bf9\u751f\u547d\u672c\u8d28\u7684\u7814\u7a76\u4e4b\u4e0a\u3002\u65e9\u671f\u7684\u7814\u7a76\u8005\u8ba4\u4e3a\uff0c\u751f\u7269\u4f53\u7684\u6784\u6210\u6750\u6599\u4e0e\u975e\u751f\u7269\u4f53\u7684\u6709\u7740\u6839\u672c\u7684\u533a\u522b\uff0c\u524d\u8005\u79f0\u4e3a\u6709\u673a\u7269\uff0c\u540e\u8005\u79f0\u4e3a\u65e0\u673a\u7269\uff0c\u4e14\u524d\u8005\u53ea\u80fd\u6765\u81ea\u751f\u7269\u4f53\u800c\u4e0d\u80fd\u4eba\u4e3a\u5730\u7528\u540e\u8005\u5408\u6210\u30021828\u5e74\uff0c\u5fb7\u56fd\u5316\u5b66\u5bb6\u7ef4\u52d2<\/span>\uff08Wohler F\uff09<\/span>\u9996\u6b21\u5728\u5b9e\u9a8c\u5ba4\u7528\u6c30\u9178\u548c\u6c28\u6c34\u4e24\u79cd\u65e0\u673a\u5206\u5b50\u5408\u6210\u4e86\u4e00\u79cd\u6709\u673a\u5206\u5b50\u201c\u5c3f\u7d20\u201d\uff0c\u4ece\u800c\u8bc1\u660e\u4e86\u6784\u6210\u751f\u547d\u7684\u7269\u8d28\u548c\u975e\u751f\u547d\u7684\u4e4b\u95f4\u5e76\u6ca1\u6709\u4e00\u4e2a\u4e0d\u53ef\u903e\u8d8a\u7684\u754c\u9650\u3002\u7814\u7a76\u8005\u7531\u6b64\u5f00\u59cb\u4e86\u751f\u7269\u4f53\u7684\u6838\u9178\u3001\u86cb\u767d\u8d28\u3001\u7cd6\u548c\u8102\u7c7b\u7b49\u5404\u79cd\u751f\u7269\u5206\u5b50\u4e4b\u7814\u7a76\uff1b\u968f\u540e\u8bde\u751f\u4e86\u4e00\u95e8\u5316\u5b66\u4e0e\u751f\u7269\u5b66\u9ad8\u5ea6\u6574\u5408\u7684\u4ea4\u53c9\u5b66\u79d1\u2014\u2014\u751f\u7269\u5316\u5b66<\/span>\uff08Biochemistry\uff09<\/span>\uff1b\u5b83\u88ab\u300a\u5927\u82f1\u767e\u79d1\u5168\u4e66\u300b\u5b9a\u4e49\u4e3a\uff1a\u6d89\u53ca\u53d1\u751f\u5728\u690d\u7269\u3001\u52a8\u7269\u548c\u5fae\u751f\u7269\u7684\u5316\u5b66\u7269\u8d28\u548c\u8fc7\u7a0b\u7684\u79d1\u5b66\u7814\u7a76\u9886\u57df\u3002\u4e5f\u5c31\u662f\u8bf4\uff0c\u5728\u7814\u7a76\u8005\u7684\u773c\u91cc\uff0c\u751f\u547d\u53ea\u4e0d\u8fc7\u662f\u5316\u5b66\u7814\u7a76\u4e2d\u4e00\u79cd\u7279\u5b9a\u7684\u5bf9\u8c61\uff0c\u5b83\u7684\u5b58\u5728\u53ca\u5176\u529f\u80fd\u90fd\u5efa\u7acb\u5728\u5176\u6784\u6210\u6750\u6599\u4ee5\u53ca\u6784\u6210\u65b9\u5f0f\u4e4b\u4e0a\u3002<\/span><\/p>\n

\u751f\u547d\u79d1\u5b66\u9886\u57df\u4e2d\u6700\u91cd\u8981\u7684\u4ea4\u53c9\u5b66\u79d1\u662f\u8bde\u751f\u4e8e20\u4e16\u7eaa\u4e2d\u53f6\u7684\u5206\u5b50\u751f\u7269\u5b66\u300220\u4e16\u7eaa40\u5e74\u4ee3\uff0c\u5965\u5730\u5229\u7269\u7406\u5b66\u5bb6\u859b\u5b9a\u8c14<\/span>\uff08Schr\u00f6dinger E\uff09<\/span>\u53d1\u8868\u4e86\u300a\u751f\u547d\u662f\u4ec0\u4e48\u300b\u4e00\u4e66\uff1b\u4ed6\u5728\u4e66\u4e2d\u660e\u786e\u63d0\u51fa\uff0c\u751f\u547d\u548c\u975e\u751f\u547d\u4e00\u6837\uff0c\u201c\u5728\u5b83\u5185\u90e8\u53d1\u751f\u7684\u4e8b\u4ef6\u5fc5\u987b\u9075\u5faa\u4e25\u683c\u7684\u7269\u7406\u5b66\u5b9a\u5f8b\u201d[2]\uff1b\u56e0\u6b64\uff0c\u7814\u7a76\u8005\u53ef\u4ee5\u901a\u8fc7\u7269\u7406\u548c\u5316\u5b66\u7684\u6280\u672f\u548c\u65b9\u6cd5\u6765\u7814\u7a76\u751f\u7269\u4f53\u7684\u5c5e\u6027\u6216\u7279\u5f81\u3002\u6700\u6709\u4ee3\u8868\u6027\u7684\u662f\u7f8e\u56fd\u5316\u5b66\u5bb6\u9c8d\u6797<\/span>\uff08Pauling L\uff09<\/span>\u5bf9\u86cb\u767d\u8d28\u7a7a\u95f4\u7ed3\u6784\u7684\u7814\u7a76\uff1b\u4ed6\u5e94\u7528\u91cf\u5b50\u5316\u5b66\u548cX\u5c04\u7ebf\u6676\u4f53\u5b66\u6280\u672f\u5206\u6790\u4e86\u86cb\u767d\u8d28\u4e0a\u8fde\u63a5\u6c28\u57fa\u9178\u6b8b\u57fa\u7684\u80bd\u952e<\/span>\uff08C\uff0dN\u952e\uff09<\/span>\uff0c\u8ba4\u4e3a\u80bd\u952e\u5177\u6709\u90e8\u5206\u53cc\u952e\u7684\u6027\u8d28\u800c\u4e0d\u80fd\u81ea\u7531\u65cb\u8f6c\uff0c\u5bfc\u81f4\u8fde\u63a5\u80bd\u952e\u4e24\u7aef6\u4e2a\u539f\u5b50\u7684\u7a7a\u95f4\u4f4d\u7f6e\u5904\u5728\u4e00\u4e2a\u76f8\u5bf9\u63a5\u8fd1\u7684\u5e73\u9762\u4e0a\uff0c\u79f0\u4e3a\u201c\u80bd\u952e\u5e73\u9762\u201d\uff1b\u4ed6\u5728\u6b64\u57fa\u7840\u4e0a\u8fdb\u4e00\u6b65\u63d0\u51fa\uff0c\u86cb\u767d\u8d28\u5185\u7684\u5404\u4e2a\u80bd\u952e\u5e73\u9762\u4e4b\u95f4\u53ef\u4ee5\u901a\u8fc7\u8fde\u63a5\u5b83\u4eec\u7684\u03b1-\u78b3\u539f\u5b50\u8fdb\u884c\u65cb\u8f6c\uff0c\u4ece\u800c\u53ef\u4ee5\u5f62\u6210\u03b1\u87ba\u65cb\u7b49\u4e8c\u7ea7\u7ed3\u6784\u3002\u6b64\u5916\uff0c\u8457\u540d\u7684DNA\u53cc\u87ba\u65cb\u7ed3\u6784\u4e5f\u540c\u6837\u662f\u5728\u7269\u7406\u5b66\u5bb6\u3001\u5316\u5b66\u5bb6\u548c\u751f\u7269\u5b66\u5bb6\u7684\u901a\u529b\u5408\u4f5c\u4e0b\u5f97\u4ee5\u9610\u660e\uff1b\u800c\u9057\u4f20\u5bc6\u7801\u7684\u4e3b\u8981\u63d0\u51fa\u4eba\u5219\u662f\u8457\u540d\u7684\u7269\u7406\u5b66\u5bb6\u4f3d\u83ab\u592b<\/span>\uff08Gamow G\uff09<\/span>\u3002\u7531\u6b64\u53ef\u89c1\uff0c\u5206\u5b50\u751f\u7269\u5b66\u662f\u9ad8\u5ea6\u6574\u5408\u4e86\u7269\u7406\u5b66\u3001\u5316\u5b66\u548c\u751f\u7269\u5b66\u7684\u4e00\u95e8\u4ea4\u53c9\u5b66\u79d1<\/span>\uff08\u56feA\uff09<\/span>\u3002<\/span><\/p>\n

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\n<\/section>\n

\u5c3d\u7ba1\u591a\u5b66\u79d1\u7814\u7a76\u63a8\u52a8\u4e86\u751f\u7269\u5316\u5b66\u548c\u5206\u5b50\u751f\u7269\u5b66\u7b49\u4ea4\u53c9\u5b66\u79d1\u7684\u8bde\u751f\uff0c\u8fdb\u800c\u4f7f\u5f97\u751f\u547d\u79d1\u5b66\u572820\u4e16\u7eaa\u4e0b\u534a\u53f6\u53d6\u5f97\u4e86\u5de8\u5927\u7684\u53d1\u5c55\uff0c\u4f46\u7814\u7a76\u8005\u8fd8\u5e0c\u671b\u8981\u8fdb\u4e00\u6b65\u63d0\u5347\u591a\u5b66\u79d1\u7814\u7a76\u7684\u80fd\u529b\uff0c\u4ee5\u6ee1\u8db3\u7ef4\u62a4\u4eba\u7c7b\u5065\u5eb7\u548c\u9632\u6b62\u73af\u5883\u6c61\u67d3\u7b49\u91cd\u5927\u793e\u4f1a\u9700\u6c42\u30022001\u5e74\u672b\uff0c\u7f8e\u56fd\u7684\u56fd\u5bb6\u79d1\u5b66\u57fa\u91d1\u4f1a<\/span>\uff08NSF\uff09<\/span>\u7b49\u653f\u5e9c\u90e8\u95e8\u56f4\u7ed5\u7740\u201c\u4f1a\u805a\u56db\u5927\u6280\u672f\uff0c\u63d0\u5347\u4eba\u7c7b\u80fd\u529b\u201d\u7684\u4e3b\u9898\uff0c\u4e3e\u884c\u4e86\u4e00\u6b21\u79d1\u5b66\u5bb6\u4e0e\u653f\u5e9c\u5b98\u5458\u7b49\u5404\u754c\u4eba\u7269\u53c2\u4e0e\u7684\u7814\u8ba8\u4f1a\uff1b\u5728\u4f1a\u8bae\u4e0a\u9996\u6b21\u63d0\u51fa\u4e86\u201c\u4f1a\u805a\u6280\u672f\u201d<\/span>\uff08Converging Technologies\uff09<\/span>\u7684\u6982\u5ff5\uff0c\u5e76\u7279\u522b\u5f3a\u8c03\u4e86\u6765\u81ea\u56db\u4e2a\u79d1\u5b66\u6280\u672f\u9886\u57df\u534f\u540c\u4f5c\u7528\u7684\u201c\u4f1a\u805a\u6280\u672f\u201d\u2014\u2014\u7eb3\u7c73\u6280\u672f\u3001\u751f\u7269\u6280\u672f\u3001\u4fe1\u606f\u6280\u672f\u548c\u8ba4\u77e5\u79d1\u5b66<\/span>\uff08\u5176\u7b80\u5316\u82f1\u6587\u7684\u8054\u5f0f\u4e3aNano-Bio-Info-Cogno\uff0c\u7f29\u5199\u4e3aNBIC\uff09<\/span>\u3002NSF\u57fa\u4e8e\u8fd9\u6b21\u4f1a\u8bae\u7f16\u5199\u4e86\u4e00\u4efd\u62a5\u544a\uff1a\u300a\u63d0\u5347\u4eba\u7c7b\u80fd\u529b\u7684\u4f1a\u805a\u6280\u672f\u300b\u3002<\/span><\/p>\n

\u4f1a\u805a\u79d1\u5b66\u7814\u7a76\u7684\u76ee\u6807\u4e0e20\u4e16\u7eaa\u751f\u7269\u5b66\u9886\u57df\u7684\u4ea4\u53c9\u5b66\u79d1\u7814\u7a76\u7684\u76ee\u6807\u6709\u660e\u663e\u7684\u533a\u522b\uff0c\u540e\u8005\u662f\u8981\u63ed\u793a\u751f\u547d\u7684\u6d3b\u52a8\u89c4\u5f8b\uff0c\u5c5e\u4e8e\u57fa\u7840\u7814\u7a76\u9886\u57df\uff1b\u800c\u524d\u8005\u5219\u662f\u8981\u63d0\u9ad8\u793e\u4f1a\u7684\u521b\u65b0\u80fd\u529b\u6216\u6ee1\u8db3\u793e\u4f1a\u91cd\u5927\u9700\u6c42\uff0c\u5c5e\u4e8e\u5e94\u7528\u7814\u7a76\u9886\u57df\u3002\u4f8b\u5982\uff0c\u7f8e\u56fd\u9ebb\u7701\u7406\u5de5\u5b66\u9662<\/span>\uff08MIT\uff09<\/span>\u57282016\u5e74\u53d1\u5e03\u4e86\u4e00\u4efd\u62a5\u544a\uff0c\u9898\u76ee\u5c31\u662f\u201c\u4f1a\u805a\uff1a\u5065\u5eb7\u7814\u7a76\u9886\u57df\u7684\u672a\u6765\u201d<\/span>\uff08<\/span>Convergence: The future of health.\uff09<\/span>\u3002\u5728\u7f8e\u56fd\u79d1\u5b66\u5bb6\u590f\u666e<\/span>\uff08Sharp PA\uff09<\/span>\u7b49\u4eba\u770b\u6765\uff0c\u5206\u5b50\u751f\u7269\u5b66\u548c\u57fa\u56e0\u7ec4\u5b66\u662f\u8fc7\u53bb\u751f\u7269\u533b\u5b66\u9886\u57df\u7684\u4e24\u6b21\u9769\u547d\uff0c\u800c\u4f1a\u805a\u7814\u7a76\u5219\u4ee3\u8868\u7b2c\u4e09\u6b21\u751f\u7269\u533b\u5b66\u9769\u547d\uff0c\u201c\u5de5\u7a0b\u5e08\u548c\u7269\u8d28\u79d1\u5b66\u7814\u7a76\u8005\u5c06\u4e0e\u751f\u7269\u5b66\u5bb6\u548c\u533b\u751f\u4e00\u9053\u53bb\u89e3\u7b54\u4f17\u591a\u65b0\u7684\u533b\u5b66\u6311\u6218\u201d[4]\u3002\u4ed6\u4eec\u8fd8\u7279\u522b\u901a\u8fc7\u201c\u7ec4\u7ec7\u5de5\u7a0b\u201d<\/span>\uff08Tissue-engineering\uff09<\/span>\u4e3a\u4f8b\u8ba8\u8bba\u4e86\u4f1a\u805a\u7814\u7a76\u4e0e\u4ea4\u53c9\u5b66\u79d1\u7814\u7a76\u7684\u4e0d\u540c\uff1a\u201c\u8fd9\u4e0d\u540c\u4e8e\u5178\u578b\u7684\u4ea4\u53c9\u5b66\u79d1\u5f62\u6001<\/span>\uff08interdisciplinary situation\uff09<\/span>\u2014\u2014\u628a\u4e00\u79cd\u786e\u5b9a\u7684\u7ec6\u80de\u7c7b\u578b\u7ed9\u5de5\u7a0b\u5e08\u6216\u8005\u8ba9\u5de5\u7a0b\u5e08\u80fd\u591f\u786e\u5b9a\u5728\u67d0\u79cd\u751f\u7269\u7cfb\u7edf\u4e2d\u4ec0\u4e48\u6837\u7684\u6750\u6599\u662f\u6709\u7528\u7684\uff1b\u76f8\u53cd\uff0c\u8fd9\u79cd\uff08\u7ec4\u7ec7\u5de5\u7a0b\uff09\u4ece\u4e00\u5f00\u59cb\u5c31\u8981\u8fdb\u884c\u591a\u5b66\u79d1\u5408\u4f5c<\/span>\uff08<\/span>multidisciplinary collaboration\uff09<\/span>\uff0c\u6240\u6709\u7684\u53c2\u4e0e\u8005\u90fd\u8981\u6709\u5171\u540c\u7684\u53c2\u8003\u70b9\u548c\u8bed\u8a00\u3002\u8fd9\u4e00\u9886\u57df\u5982\u679c\u6ca1\u6709\u4f1a\u805a\u65b9\u6cd5<\/span>\uff08convergence approach\uff09<\/span>\u662f\u4e0d\u4f1a\u5b58\u5728\u7684\u201d[4]\u3002<\/span><\/p>\n

\u4f1a\u805a\u7814\u7a76\u7684\u4e00\u4e2a\u91cd\u8981\u7279\u70b9\u662f\u5bf9\u5de5\u7a0b\u5b66\u7684\u5f3a\u8c03\uff1b\u8fd9\u4e0e\u4f1a\u805a\u7814\u7a76\u504f\u91cd\u5e94\u7528\u7684\u76ee\u6807\u662f\u9ad8\u5ea6\u4e00\u81f4\u7684\uff1b\u4f8b\u5982\uff0c\u7f8e\u56fd\u79d1\u5b66\u9662\u7814\u7a76\u7406\u4e8b\u4f1a2014\u5e74\u53d1\u8868\u7684\u6218\u7565\u62a5\u544a\u7684\u9898\u76ee\u5c31\u662f\u201c\u4f1a\u805a\u89c2\uff1a\u63a8\u52a8\u8de8\u5b66\u79d1\u878d\u5408\u2014\u2014\u751f\u547d\u79d1\u5b66\u4e0e\u7269\u8d28\u79d1\u5b66\u548c\u5de5\u7a0b\u5b66\u7b49\u5b66\u79d1\u7684\u8de8\u754c\u201d\u3002\u5de5\u7a0b\u5b66\u7684\u4ecb\u5165\u4e0d\u4ec5\u63a8\u52a8\u7814\u7a76\u5de5\u4f5c\u8fdb\u5165\u5e94\u7528\u9886\u57df\uff0c\u800c\u4e14\u80fd\u591f\u4ea7\u751f\u5177\u6709\u5de5\u7a0b\u7279\u8272\u7684\u6210\u679c\uff0c\u5982\u7f8e\u56fd\u79d1\u5b66\u5bb6\u590f\u666e\u7b49\u4eba\u5728\u8bc4\u8bba\u6587\u7ae0\u201c\u5b9e\u73b0\u4f1a\u805a\u5728\u536b\u751f\u4fdd\u5065\u4e2d\u7684\u4ef7\u503c\uff1a\u6574\u5408\u7269\u8d28\u79d1\u5b66\u3001\u5de5\u7a0b\u5b66\u548c\u751f\u7269\u533b\u5b66\u201d\u4e2d\u6307\u51fa\uff1a\u5de5\u7a0b\u5b66\u5728\u751f\u7269\u76f8\u5bb9\u6027\u6750\u6599\u548c\u7eb3\u7c73\u6280\u672f\u9886\u57df\u53d1\u5c55\u4e86\u5168\u65b0\u7684\u7b56\u7565\uff0c\u8fd9\u79cd\u7b56\u7565\u5728\u4fc3\u8fdb\u536b\u751f\u4fdd\u5065\u65b9\u9762\u5177\u6709\u524d\u6240\u672a\u6709\u7684\u6f5c\u529b[5]\u3002<\/span><\/p>\n

\u4f1a\u805a\u7814\u7a76\u7684\u53e6\u5916\u4e00\u4e2a\u91cd\u8981\u7279\u70b9\u662f\u5bf9\u6280\u672f\u7684\u5f3a\u8c03\uff0c\u4e00\u65b9\u9762\u662f\u9ad8\u5ea6\u91cd\u89c6\u6280\u672f\u5728\u5e94\u7528\u5c42\u9762\u7684\u4ef7\u503c\uff0c\u5982\u201cNBIC\u201d\u4f1a\u805a\u6280\u672f\u7684\u63d0\u51fa\uff0c\u4f53\u73b0\u51fa\u56f4\u7ed5\u7740\u4f1a\u805a\u7814\u7a76\u76ee\u6807\u7684\u79d1\u5b66\u4e0e\u6280\u672f\u5916\u5728\u7684\u4e00\u4f53\u5316\uff1b\u53e6\u4e00\u65b9\u9762\u8fd8\u5f3a\u8c03\u4e86\u4e0d\u540c\u5b66\u79d1\u7684\u6280\u672f\u5728\u63a8\u8fdb\u4ea4\u53c9\u7814\u7a76\u672c\u8eab\u7684\u4ef7\u503c\u2014\u2014\u5305\u62ec\u5b9e\u9a8c\u4eea\u5668\u548c\u6750\u6599\u3001\u5206\u6790\u65b9\u6cd5\u548c\u6280\u672f\u7b49\uff0c\u5373\u6ce8\u91cd\u7814\u7a76\u8fc7\u7a0b\u4e2d\u79d1\u5b66\u4e0e\u6280\u672f\u5185\u5728\u7684\u4e00\u4f53\u5316\uff0c\u4ece\u5b9e\u9a8c\u5bf9\u8c61\u5230\u5b9e\u9a8c\u64cd\u4f5c\u518d\u5230\u5b9e\u9a8c\u7ed3\u679c\u3002\u7531\u6b64\u53ef\u4ee5\u770b\u5230\uff0c\u65b0\u5174\u7684\u4ea4\u53c9\u5b66\u79d1\u5982\u201c\u5316\u5b66\u751f\u7269\u5b66\u201d<\/span>(Chemical Biology)<\/span>\u548c\u201c\u7269\u7406\u751f\u7269\u5b66\u201d<\/span>\uff08Physical Biology\uff09<\/span>\u7b49\u4e0e\u4f20\u7edf\u7684\u4ea4\u53c9\u5b66\u79d1\u5982\u201c\u751f\u7269\u5316\u5b66\u201d<\/span>\uff08Biochemistry\uff09<\/span>\u548c\u201c\u751f\u7269\u7269\u7406\u5b66\u201d<\/span>\uff08Biophysics\uff09<\/span>\u6709\u7740\u5de8\u5927\u7684\u5dee\u522b\uff1b\u524d\u8005\u5f3a\u8c03\u7814\u7a76\u8005\u5e94\u7528\u5316\u5b66\u548c\u7269\u7406\u7684\u6709\u5173\u6280\u672f\u6765\u5f00\u5c55\u751f\u7269\u5b66\u7814\u7a76\uff0c\u5982\u5316\u5b66\u751f\u7269\u5b66\u7684\u4e00\u4f4d\u521b\u59cb\u4eba\u66fe\u8fd9\u6837\u8bf4\u8fc7\uff1a\u6211\u4eec\u7684\u76ee\u6807\u662f\u4e3a\u6bcf\u4e00\u4e2a\u57fa\u56e0\u627e\u5230\u76f8\u5e94\u7684\u5c0f\u5206\u5b50\u5316\u5408\u7269\uff0c\u7528\u5b83\u4eec\u6765\u5206\u6790\u7ec6\u80de\u548c\u6709\u673a\u4f53\u7684\u529f\u80fd\uff1b\u300a\u81ea\u7136\u00b7\u5316\u5b66\u751f\u7269\u5b66\u300b\u521b\u520a\u65f6\u53d1\u8868\u7684\u793e\u8bba\u662f\u8fd9\u6837\u8bf4\u7684\uff1a\u201c\u5316\u5b66\u751f\u7269\u5b66\u4f5c\u4e3a\u4e00\u4e2a\u65b0\u9886\u57df\uff0c\u662f\u690d\u6839\u4e8e\u5316\u5b66\u5bb6\u548c\u751f\u7269\u5b66\u5bb6\u7d27\u5bc6\u5408\u4f5c\u5e26\u6765\u7684\u6280\u672f\u8fdb\u6b65\u4e4b\u4e0a\u201d[6]\u3002<\/span><\/p>\n

\u4f1a\u805a\u79d1\u5b66\u7814\u7a76\u7684\u8fd9\u4e9b\u7279\u70b9\u63d0\u793a\u6211\u4eec\uff0c\u8fd9\u663e\u7136\u662f\u4e0d\u540c\u4e8e\u4ea4\u53c9\u5b66\u79d1\u7814\u7a76\u5f62\u6001\u7684\u53e6\u4e00\u79cd\u591a\u5b66\u79d1\u7814\u7a76\u5f62\u6001\u3002\u524d\u8005\u5f80\u5f80\u901a\u8fc7\u4e0d\u540c\u5b66\u79d1\u4e4b\u95f4\u7684\u9ad8\u5ea6\u6574\u5408\u800c\u5f62\u6210\u5168\u65b0\u7684\u4ea4\u53c9\u5b66\u79d1\uff0c\u5982\u751f\u7269\u5316\u5b66\u6216\u5206\u5b50\u751f\u7269\u5b66\uff1b\u800c\u540e\u8005\u5219\u8868\u73b0\u4e3a\u4e0d\u540c\u5b66\u79d1\u4e4b\u95f4\u7684\u76f8\u4e92\u534f\u4f5c\uff0c\u5982\u5316\u5b66\u751f\u7269\u5b66\u6216\u7269\u7406\u751f\u7269\u5b66\u3002\u4f1a\u805a\u79d1\u5b66\u7814\u7a76\u5f3a\u8c03\u7684\u4e0d\u662f\u5b66\u79d1\u95f4\u7684\u201c\u4ea4\u53c9\u201d\uff0c\u800c\u662f\u4e0d\u540c\u5b66\u79d1\u7684\u201c\u4f1a\u805a\u201d<\/span>\uff08\u6bd4\u8f83\u56feA\u548cB\uff09<\/span>\u3002\u6362\u53e5\u8bdd\u8bf4\uff0c\u5404\u95e8\u5b66\u79d1\u4ee3\u8868\u4e86\u4e0d\u540c\u7684\u4e13\u4e1a\u5316\u5206\u5de5\uff0c\u800c\u4f1a\u805a\u7814\u7a76\u5219\u662f\u628a\u8fd9\u4e9b\u4e13\u4e1a\u4e2d\u76f8\u5173\u7684\u6280\u672f\u548c\u7406\u8bba\u8fdb\u884c\u96c6\u6210\uff0c\u4ee5\u4fbf\u9488\u5bf9\u7ef4\u62a4\u5065\u5eb7\u6216\u5f00\u53d1\u65b0\u80fd\u6e90\u7b49\u56fd\u5bb6\/\u793e\u4f1a\u7684\u91cd\u5927\u9700\u6c42\u53bb\u5efa\u7acb\u6216\u53d1\u5c55\u65b0\u7684\u6280\u672f\u65b9\u6cd5\u3002\u6b63\u5982\u7f8e\u56fd\u79d1\u5b66\u9662\u5173\u4e8e\u4f1a\u805a\u7814\u7a76\u7684\u6218\u7565\u62a5\u544a\u6240\u6307\u51fa\u7684\u90a3\u6837\uff1a\u201c\u4f1a\u805a\u89c2\u4f53\u73b0\u4e86\u4e00\u79cd\u4ea4\u53c9\u5b66\u79d1\u7814\u7a76\u7684\u6269\u5c55\u5f62\u5f0f\uff0c\u4e13\u4e1a\u77e5\u8bc6\u6784\u6210\u4e86\u7814\u7a76\u6d3b\u52a8\u7684\u2018\u5b8f\u89c2\u2019\u6a21\u5757\uff0c\u800c\u5404\u4e2a\u2018\u5b8f\u89c2\u2019\u6a21\u5757\u53c8\u7ec4\u5408\u5f62\u6210\u4e00\u4e2a\u66f4\u5927\u7684\u6574\u4f53\u201d[7]\u3002<\/span><\/p>\n

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21\u4e16\u7eaa\u4e4b\u521d\u4eba\u7c7b\u57fa\u56e0\u7ec4\u8ba1\u5212\u7684\u5b9e\u65bd\u63a8\u52a8\u751f\u547d\u79d1\u5b66\u8fdb\u5165\u4e86\u5927\u6570\u636e\u65f6\u4ee3\u3002\u4eba\u7684\u57fa\u56e0\u7ec4\u62e5\u670930\u4ebf\u4e2a\u7684\u78b1\u57fa\u5bf9\uff0c\u5373\u76f8\u5f53\u4e8e3Gb\u7684\u6570\u636e\uff1b\u76ee\u524d\u56fd\u9645\u4e0a\u50a8\u5b58\u7684\u4e2a\u4f53\u57fa\u56e0\u7ec4\u5e8f\u5217\u7684\u6570\u636e\u91cf\u5df2\u8d85\u8fc7\u767e\u4e07\u4eba\u7ea7\uff1b\u6570\u636e\u79d1\u5b66\u5bb6\u4f30\u8ba1\u52302030\u5e74\u65f6\uff0c\u6bcf\u5e74\u4e16\u754c\u8303\u56f4\u5185\u4ea7\u751f\u7684\u57fa\u56e0\u7ec4\u6570\u636e\u5c06\u4e3a25 PB<\/span>\uff081 PB =<\/span>1015<\/sup><\/span>Byte\uff09<\/span>[8]\u3002\u5927\u6570\u636e\u5728\u533b\u7597\u5065\u5eb7\u9886\u57df\u5219\u6709\u66f4\u660e\u663e\u7684\u589e\u957f\uff0c\u5982\u7f8e\u56fd\u56fd\u7acb\u80bf\u7624\u7814\u7a76\u6240\u7684\u57fa\u56e0\u7ec4\u6570\u636e\u5e73\u53f0\u57282016\u5e74\u6210\u7acb\u4e4b\u540e\u7684\u7b2c\u4e00\u5e74\u5185\uff0c\u5c31\u6536\u5230\u4e86\u7814\u7a76\u8005\u63d0\u4ea4\u76844.5 PB\u7684\u6570\u636e[8]\u3002\u636e\u7edf\u8ba1\uff0c\u4e16\u754c\u8303\u56f4\u5185\u4ea7\u751f\u7684\u533b\u7597\u5065\u5eb7\u6570\u636e\u57282013\u5e74\u5927\u7ea6\u4e3a153 EB<\/span>\uff081 EB =<\/span>1018<\/sup><\/span> Byte\uff09<\/span>\uff0c\u800c\u57282020\u5e74\u4f30\u8ba1\u5c06\u589e\u957f\u52302314 EB[8]\u3002\u5982\u679c\u8bf4\u6709\u4ec0\u4e48\u662f21\u4e16\u7eaa\u7684\u751f\u547d\u79d1\u5b66\u4e43\u81f3\u6574\u4e2a\u79d1\u5b66\u6bd420\u4e16\u7eaa\u8fdb\u6b65\u7684\u6807\u5fd7\uff0c\u90a3\u5c31\u662f\u6570\u636e\u7684\u83b7\u53d6\u548c\u6570\u636e\u7684\u5229\u7528\u3002<\/span><\/p>\n

<\/span><\/p>\n

\u751f\u7269\u533b\u5b66\u5927\u6570\u636e\u4e0d\u4ec5\u4e3a\u4eba\u7c7b\u8ba4\u8bc6\u548c\u6539\u9020\u4e16\u754c\u63d0\u4f9b\u4e86\u5de8\u5927\u7684\u8d44\u6e90\uff0c\u800c\u4e14\u6539\u53d8\u4e86\u751f\u547d\u79d1\u5b66\u548c\u533b\u5b66\u7684\u591a\u5b66\u79d1\u7814\u7a76\u8303\u5f0f\uff0c\u5176\u5178\u578b\u4ee3\u8868\u6b63\u662f\u4eba\u7c7b\u57fa\u56e0\u7ec4\u8ba1\u5212\u3002\u8be5\u9879\u8ba1\u5212\u4e5f\u5c5e\u4e8e\u591a\u5b66\u79d1\u4ea4\u53c9\u7814\u7a76\uff0c\u5176\u5b9e\u65bd\u8fc7\u7a0b\u9700\u8981\u4f9d\u9760\u65b0\u578b\u6d4b\u5e8f\u4eea\u5668\u548c\u8bd5\u5242\u7684\u7814\u53d1\uff0c\u4ee5\u53ca\u6d77\u91cf\u6570\u636e\u7684\u5904\u7406\u4e0e\u5206\u6790\u7b49\uff0c\u6d89\u53ca\u5230\u7269\u7406\u5b66\u3001\u5316\u5b66\u3001\u751f\u7269\u5b66\u3001\u4fe1\u606f\u79d1\u5b66\u548c\u6570\u5b66\u7b49\u591a\u4e2a\u5b66\u79d1\u3002\u4f46\u4e0e\u5047\u8bbe\u9a71\u52a8\u7684\u5b66\u79d1\u4ea4\u53c9\u7814\u7a76\u4e0d\u4e00\u6837\u7684\u662f\uff0c\u8be5\u9879\u8ba1\u5212\u5c5e\u4e8e\u201c\u53d1\u73b0\u7684\u79d1\u5b66\u201d<\/span>\uff08Discovery science\uff09<\/span>\uff0c\u662f\u8981\u83b7\u5f97\u6709\u5173\u4eba\u4f53\u7ec6\u80de\u57fa\u56e0\u7ec4\u7684\u5168\u90e8\u6838\u82f7\u9178\u5e8f\u5217\u7684\u6570\u636e\u3002\u4e5f\u5c31\u662f\u8bf4\uff0c\u8fd9\u9879\u7814\u7a76\u8868\u73b0\u51fa\u4e86\u4e00\u79cd\u65b0\u7684\u7814\u7a76\u8303\u5f0f\u2014\u2014\u6570\u636e\u9a71\u52a8\u7684\u7814\u7a76\u8303\u5f0f\uff0c\u5f00\u5c55\u7814\u7a76\u7684\u51fa\u53d1\u70b9\u4e0d\u662f\u79d1\u5b66\u5047\u8bbe\uff0c\u800c\u662f\u9ad8\u901a\u91cf\u7684\u6570\u636e\u91c7\u96c6\u80fd\u529b\uff1b\u800c\u7814\u7a76\u7684\u76ee\u6807\u4e5f\u4e0d\u662f\u53bb\u89e3\u51b3\u67d0\u4e2a\u5177\u4f53\u7684\u79d1\u5b66\u95ee\u9898\uff0c\u800c\u662f\u8981\u53bb\u83b7\u53d6\u6d77\u91cf\u7684\u6570\u636e\u3002<\/span><\/p>\n

\u6570\u636e\u9a71\u52a8\u7684\u7814\u7a76\u8303\u5f0f\u6709\u4e00\u4e2a\u91cd\u8981\u7684\u7279\u5f81\uff1a\u201c\u8fed\u4ee3\u201d<\/span>\uff08iterate\uff09<\/span>\uff0c\u5373\u6bcf\u4e00\u6b21\u7814\u7a76\u5de5\u4f5c\u53ef\u4ee5\u662f\u4e00\u79cd\u4e0d\u5b8c\u5907\u7684\u9636\u6bb5\u6027\u5de5\u4f5c\uff0c\u7136\u540e\u5728\u524d\u671f\u7814\u7a76\u7ed3\u679c\u7684\u57fa\u7840\u4e0a\u53cd\u590d\u5730\u8fdb\u884c\u5b8c\u5584\uff0c\u901a\u8fc7\u591a\u6b21\u7814\u7a76\u9010\u6e10\u903c\u8fd1\u9884\u5b9a\u7684\u603b\u4f53\u76ee\u6807\u3002\u4eba\u7c7b\u57fa\u56e0\u7ec4\u8ba1\u5212\u660e\u663e\u5177\u6709\u8fd9\u79cd\u201c\u8fed\u4ee3\u201d\u7279\u5f81\uff0c\u5c3d\u7ba1\u5176\u7ec8\u6781\u76ee\u6807\u662f\u63ed\u793a\u4eba\u7c7b\u57fa\u56e0\u7ec4\u7684\u6240\u6709\u6838\u9178\u5e8f\u5217\uff0c\u4f46\u57282001\u5e742\u6708\u53d1\u8868\u7684\u4eba\u7c7b\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u6210\u679c\u53ea\u4e0d\u8fc7\u662f\u4e00\u4e2a\u8986\u76d6\u4e86\u57fa\u56e0\u7ec490%\u6838\u9178\u5e8f\u5217\u7684\u201c\u8349\u56fe\u201d\uff1b2004\u5e7410\u6708\u5728\u300a\u81ea\u7136\u300b\u5468\u520a\u4e0a\u53d1\u8868\u4e86\u4eba\u7c7b\u57fa\u56e0\u7ec4\u5168\u56fe\u7684\u8bba\u6587\uff0c\u4e5f\u53ea\u7ed9\u51fa\u4e86\u5e38\u67d3\u8272\u8d28\u533a\u57df\u5185\u5927\u7ea699%\u6838\u9178\u5e8f\u5217\u7684\u6d4b\u5b9a\u7ed3\u679c\u3002\u4e8b\u5b9e\u4e0a\uff0c\u4eba\u7c7b\u57fa\u56e0\u7ec4\u7684\u6838\u9178\u5e8f\u5217\u4e2d\u81f3\u4eca\u4ecd\u7136\u5b58\u5728\u8bb8\u591a\u9ad8\u5ea6\u91cd\u590d\u5e8f\u5217\u533a\u57df<\/span>\uff08\u5982\u4e2d\u5fc3\u7c92\uff09<\/span>\u6ca1\u6709\u88ab\u6d4b\u5b9a\uff1b2020\u5e749\u6708\uff0c\u7814\u7a76\u8005\u7ec8\u4e8e\u5728\u300a\u81ea\u7136\u300b\u5468\u520a\u4e0a\u53d1\u8868\u4e86\u4eba\u7c7b\u7b2c\u4e00\u6761\u5b8c\u6574\u7684\u3001\u6ca1\u6709\u6d4b\u5e8f\u201c\u7f3a\u53e3\u201d\u7684\u67d3\u8272\u4f53\u7684\u6838\u9178\u5e8f\u5217\uff0c\u4f46\u4ecd\u7136\u8fd8\u670922\u6761\u4eba\u7c7b\u67d3\u8272\u4f53\u4e0a\u7684\u5e8f\u5217\u201c\u7f3a\u53e3\u201d\u5f85\u7814\u7a76\u8005\u53bb\u8865\u6d4b\u3002\u4e0d\u4e45\u524d\uff0c\u4e00\u4e2a\u6bd4\u201c\u4eba\u7c7b\u57fa\u56e0\u7ec4\u8ba1\u5212\u201d\u66f4\u4e3a\u5b8f\u5927\u7684\u201c\u4eba\u7c7b\u7ec6\u80de\u56fe\u8c31\u201d<\/span>\uff08Human Cell Atlas\uff0cHCA\uff09<\/span>\u7814\u7a76\u8ba1\u5212\u6b63\u5f0f\u542f\u52a8\uff0c\u5176\u57fa\u672c\u76ee\u6807\u662f\uff0c\u901a\u8fc7\u5404\u79cd\u5355\u7ec6\u80de\u5206\u6790\u6280\u672f\u6765\u9274\u5b9a\u4eba\u4f53\u62e5\u6709\u768440\u523060\u4e07\u4ebf\u4e2a\u4f53\u7ec6\u80de\u4e2d\u7684\u6240\u6709\u7ec6\u80de\u7c7b\u578b\uff1b\u5176\u91c7\u7528\u7684\u4e3b\u8981\u7814\u7a76\u7b56\u7565\u4e5f\u660e\u663e\u5177\u6709\u201c\u8fed\u4ee3\u201d\u7279\u5f81[9]\u3002<\/span><\/p>\n

\u6570\u636e\u9a71\u52a8\u7684\u7814\u7a76\u8303\u5f0f\u7684\u53e6\u4e00\u4e2a\u91cd\u8981\u7279\u5f81\u662f\u7814\u7a76\u7684\u201c\u5f00\u653e\u6027\u201d\uff0c\u5373\u4e0d\u53d7\u5df2\u6709\u7406\u8bba\u6846\u67b6\u7684\u9650\u5236\u300220\u4e16\u7eaa\u751f\u547d\u79d1\u5b66\u7684\u4e3b\u6d41\u662f\u5047\u8bbe\u9a71\u52a8\u7684\u7814\u7a76\u8303\u5f0f\uff0c\u4ee5\u89e3\u51b3\u5177\u4f53\u7684\u79d1\u5b66\u95ee\u9898\u4e3a\u4e3b\u8981\u76ee\u6807\uff1b\u5176\u7814\u7a76\u5de5\u4f5c\u7684\u5f00\u5c55\u662f\u4f9d\u8d56\u4e8e\u65e2\u6709\u7684\u7406\u8bba\u6846\u67b6\uff0c\u4ece\u800c\u4f7f\u5f97\u7814\u7a76\u8005\u5728\u4e8b\u5b9e\u7684\u9009\u62e9\u548c\u7406\u89e3\u65b9\u9762\u5bb9\u6613\u53d7\u9650\u4e8e\u6307\u5bfc\u7814\u7a76\u7684\u7406\u8bba\u6846\u67b6\u3002\u800c\u6570\u636e\u9a71\u52a8\u7684\u7814\u7a76\u8303\u5f0f\u5219\u4e0d\u4ec5\u80fd\u591f\u8ba9\u7814\u7a76\u8005\u907f\u514d\u7406\u8bba\u6846\u67b6\u5e26\u6765\u7684\u4e3b\u89c2\u504f\u89c1\uff0c\u800c\u4e14\u53ef\u4ee5\u5e2e\u52a9\u5176\u53d1\u73b0\u5728\u5047\u8bbe\u6216\u8005\u73b0\u6709\u7406\u8bba\u8303\u56f4\u4e4b\u5916\u7684\u5168\u65b0\u77e5\u8bc6\u3002\u6b63\u5982\u7f8e\u56fd\u751f\u7269\u5b66\u5bb6\u6208\u5362\u4f2f<\/span>\uff08Golub T\uff09<\/span>\u5728\u4e00\u7bc7\u9898\u4e3a\u201c\u6570\u636e\u4f18\u5148\u201d\u7684\u6587\u7ae0\u4e2d\u6240\u6307\u51fa\u7684\uff1a\u201c\u5982\u679c\u6ca1\u6709\u83b7\u5f97\u5168\u9762\u7684\u80bf\u7624\u57fa\u56e0\u7ec4\u6570\u636e\uff0c\u5c06\u96be\u4ee5\u533a\u5206\u4fe1\u53f7\u548c\u566a\u97f3\u3002\u5c3d\u7ba1\u5047\u8bbe\u9a71\u52a8\u7684\u5b9e\u9a8c\u79d1\u5b66\u4f9d\u7136\u5904\u4e8e\u7814\u7a76\u9886\u57df\u7684\u4e2d\u5fc3\u4f4d\u7f6e\uff0c\u4f46\u4e0d\u5e26\u504f\u597d\u7684\u80bf\u7624\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u5c06\u63d0\u4f9b\u524d\u6240\u672a\u6709\u7684\u673a\u4f1a\u53bb\u50ac\u751f\u65b0\u7684\u60f3\u6cd5\u201d[10]\u3002<\/span><\/p>\n

\u6570\u636e\u9a71\u52a8\u7684\u7814\u7a76\u8303\u5f0f\u7684\u201c\u5f00\u653e\u6027\u201d\u7279\u5f81\uff0c\u4f7f\u5f97\u7814\u7a76\u5de5\u4f5c\u4ece\u8ffd\u6c42\u4e8b\u7269\u4e4b\u95f4\u7684\u56e0\u679c\u5173\u7cfb\u8f6c\u53d8\u4e3a\u5bfb\u627e\u4e8b\u7269\u4e4b\u95f4\u7684\u76f8\u5173\u6027\u3002\u8fd9\u5c31\u5bfc\u81f4\u4e86\u8fc7\u53bb\u770b\u4e0a\u53bb\u5f7c\u6b64\u6ca1\u6709\u5173\u7cfb\u7684\u5b66\u79d1\u4ea7\u751f\u4e86\u5168\u65b0\u7684\u8054\u7cfb\uff0c\u5982\u8c37\u6b4c\u7684\u5de5\u7a0b\u5e08\u5f00\u53d1\u4e86\u4e00\u79cd\u7b97\u6cd5\uff0c\u53ef\u4ee5\u6839\u636e\u6bcf\u5929\u6c47\u603b\u7684\u8c37\u6b4c\u641c\u7d22\u6570\u636e\u8fd1\u4e4e\u5b9e\u65f6\u5730\u5bf9\u6d41\u611f\u75ab\u60c5\u8fdb\u884c\u9884\u6d4b\uff1b\u5176\u9884\u62a5\u6d41\u611f\u7206\u53d1\u7684\u5730\u57df\u6027\u548c\u65f6\u6548\u6027\u6bd4\u7f8e\u56fd\u75be\u63a7\u4e2d\u5fc3\u62a5\u7684\u8fd8\u8981\u597d[11]\u3002\u5373\u4f7f\u662f\u590d\u6742\u7684\u4eba\u7c7b\u884c\u4e3a\uff0c\u4e5f\u53ef\u4ee5\u901a\u8fc7\u5927\u6570\u636e\u7684\u5206\u6790\u548c\u8ba1\u7b97\u6765\u8fdb\u884c\u7814\u7a76\uff1b\u4e3a\u6b6410\u5e74\u524d\u5df2\u7ecf\u51fa\u73b0\u4e86\u4e00\u95e8\u76f8\u5e94\u7684\u4ea4\u53c9\u5b66\u79d1\u2014\u2014\u201c\u8ba1\u7b97\u793e\u4f1a\u79d1\u5b66\u201d<\/span>\uff08Computational social science\uff09<\/span>[12]\u3002\u8fd9\u79cd\u57fa\u4e8e\u5927\u6570\u636e\u7684\u8de8\u5b66\u79d1\u7814\u7a76\u5f62\u6210\u4e86\u591a\u5b66\u79d1\u4ea4\u53c9\u7814\u7a76\u7684\u7b2c\u4e09\u79cd\u5f62\u6001\uff0c\u5229\u7528\u6570\u636e\u79d1\u5b66\u6765\u6253\u901a\u6216\u8005\u8de8\u8d8a\u5404\u95e8\u5b66\u79d1\u7684\u8fb9\u754c<\/span>\uff08\u56feC\uff09<\/span>\u3002\u56fd\u9645\u8457\u540d\u7684\u751f\u547d\u79d1\u5b66\u671f\u520a\u300aCell\u300b\u57282020\u5e74\u521b\u7acb\u4e86\u4e00\u4e2a\u4ee5\u6570\u636e\u79d1\u5b66\u4e3a\u7ebd\u5e26\u7684\u591a\u5b66\u79d1\u7814\u7a76\u7684\u5b50\u520a\u300aPatterns\u300b\uff0c\u5176\u4e3b\u7f16\u5728\u53d1\u520a\u8bcd\u91cc\u8fd9\u6837\u5199\u5230\uff1a\u201cPatterns\u5c06\u901a\u8fc7\u6570\u636e\u79d1\u5b66\u6280\u672f\u7684\u5171\u4eab\u6765\u6253\u7834\u5404\u95e8\u5b66\u79d1\u7684\u8fb9\u754c\uff0c\u8fd9\u4e9b\u6570\u636e\u79d1\u5b66\u6280\u672f\u53ef\u4ee5\u7528\u6765\u89e3\u51b3\u8de8\u9886\u57df\u7684\u95ee\u9898\u201d [13]\u3002<\/span><\/p>\n


\n<\/span><\/p>\n

\u66f4\u91cd\u8981\u7684\u662f\uff0c\u6570\u636e\u9a71\u52a8\u7684\u7814\u7a76\u8303\u5f0f\u4f5c\u4e3a\u4e00\u79cd\u8d85\u8d8a\u7406\u8bba\u6846\u67b6\u7684\u201c\u5f00\u653e\u5f0f\u79d1\u5b66\u201d\uff0c\u5176\u7814\u7a76\u4ea7\u751f\u7684\u8d44\u6e90\u548c\u6570\u636e\u53ef\u4ee5\u88ab\u5e7f\u6cdb\u5730\u7528\u4e8e\u7814\u7a76\u5404\u79cd\u5404\u6837\u7684\u79d1\u5b66\u95ee\u9898\uff1b\u5982\u6536\u96c6\u4e8650\u4e07\u82f1\u56fd\u4eba\u7684\u751f\u7269\u6837\u672c\u548c\u5065\u5eb7\u533b\u5b66\u6570\u636e\u7684\u201c\u82f1\u56fd\u751f\u7269\u8d44\u6e90\u5e93\u201d<\/span>\uff08UK Biobank\uff09<\/span>\uff0c\u81ea2012\u5e74\u5efa\u6210\u81f3\u4eca\uff0c\u5df2\u7ecf\u7528\u4e8e\u652f\u6301\u8fc7\u4e16\u754c\u5404\u56fd\u6570\u4e07\u540d\u7814\u7a76\u4eba\u5458\u7684\u7814\u7a76\u5de5\u4f5c\uff0c\u4ec52018\u5e74\u5ea6\u5229\u7528\u8be5\u5e93\u5f00\u5c55\u7814\u7a76\u7684\u79d1\u5b66\u5bb6\u5c31\u67094\u5343\u591a\u4eba\uff0c\u53d1\u8868\u4e86\u6d89\u53ca\u5230\u5065\u5eb7\u533b\u5b66\u5404\u4e2a\u65b9\u9762\u8fd1300\u7bc7\u7814\u7a76\u8bba\u6587\u3002\u6362\u53e5\u8bdd\u8bf4\uff0c\u8fd9\u79cd\u201c\u5f00\u653e\u6027\u201c\u4f7f\u5f97\u6570\u636e\u9a71\u52a8\u7684\u7814\u7a76\u8303\u5f0f\u4e4b\u7ec4\u7ec7\u6a21\u5f0f\u660e\u663e\u4e0d\u540c\u4e8e\u5047\u8bbe\u9a71\u52a8\u7684\u7814\u7a76\u8303\u5f0f\uff0c\u524d\u8005\u5f3a\u8c03\u4f17\u591a\u7814\u7a76\u8005\u4e4b\u95f4\u7684\u5408\u4f5c\u3001\u4ea4\u6d41\u548c\u5171\u4eab\uff1b\u800c\u540e\u8005\u5219\u66f4\u6ce8\u91cd\u4ee5\u9879\u76ee\u8d1f\u8d23\u4eba<\/span>\uff08Principle Investigator, PI\uff09<\/span>\u4e3a\u4e3b\u5bfc\u7684\u201c\u4e2a\u4eba\u82f1\u96c4\u4e3b\u4e49\u201d\u5f0f\u7684\u7814\u7a76\uff1b\u6b63\u5982\u6700\u8fd1\u7684\u4e00\u7bc7\u8bc4\u8bba\u6587\u7ae0\u6240\u6307\u51fa\u7684\uff1a\u4f20\u7edf\u7684\u5353\u8d8a\u89c2\u662f\u5d07\u62dc\u5929\u624d\u800c\u4e0e\u793e\u4f1a\u73af\u5883\u65e0\u5173\uff1b\u8fd9\u79cd\u5bf9\u5353\u8d8a\u7684\u72ed\u9698\u770b\u6cd5\u5bfc\u81f4\u4e86\u8d44\u6e90\u96c6\u4e2d\u5230\u5df2\u5f97\u5230\u8ba4\u53ef\u7684\u79d1\u5b66\u5bb6\u624b\u4e2d\uff0c\u8fdb\u800c\u9650\u5236\u4e86\u79d1\u5b66\u7684\u8fdb\u6b65\u548c\u65b0\u601d\u60f3\u7684\u4ea7\u751f\uff0c\u4ee5\u53ca\u591a\u5b66\u79d1\u7814\u7a76\u9886\u57df\u7684\u53d1\u5c55[14]\u30022020\u5e7412\u6708\uff0c\u7f8e\u56fd\u79d1\u5b66\u9662\u53d1\u8868\u4e86\u4e00\u4efd\u6218\u7565\u62a5\u544a\u300a\u65e0\u6b62\u5883\u7684\u524d\u6cbf\u2014\u2014\u79d1\u5b66\u7684\u672a\u676575\u5e74\u300b\uff0c\u5728\u5176\u7ed3\u8bba\u4e2d\u7279\u522b\u6307\u51fa\uff1a\u79d1\u5b66\u6fc0\u52b1\u5236\u5ea6\u5e94\u8be5\u662f\u4e00\u79cd\u201c\u5171\u8d62\u6e38\u620f\u201d<\/span>\uff08positive-sum game\uff09<\/span>\u800c\u975e\u201c\u96f6\u5408\u6e38\u620f\u201d<\/span>\uff08zero-sum game\uff09<\/span>[15]\u3002\u663e\u7136\uff0c\u6570\u636e\u9a71\u52a8\u7684\u7814\u7a76\u8303\u5f0f\u6b63\u5728\u5bfc\u81f4\u79d1\u5b66\u7814\u7a76\u7684\u751f\u6001\u73af\u5883\u53d1\u751f\u9769\u547d\u6027\u7684\u6539\u53d8\u3002<\/span><\/p>\n

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[1] Edsall JT. The Journal of Biological Chemistry after seventy-five years. Journal Biological Chemistry, 1980, 255(19):8939\u20148951.<\/span><\/p>\n

[2] \u57c3\u5c14\u6e29\u00b7\u859b\u5b9a\u8c14.\u751f\u547d\u662f\u4ec0\u4e48.\u7f57\u6765\u9e25\uff0c\u7f57\u8fbd\u590d\uff0c\u8bd1.\u6e56\u5357\u79d1\u5b66\u6280\u672f\u51fa\u7248\u793e\uff0c\u957f\u6c99\uff1a2003:8.<\/span><\/p>\n

[3]Weinberg R. Point: Hypotheses first. Nature, 2010, 464(7289):678.<\/span><\/p>\n

[4] Sharp PA, Langer R. Promoting convergence in biomedical science. Science, 2011, 333(6042):527.<\/span><\/p>\n

[5] Sharp P,Jacks T, Hockfield S. Capitalizing on convergence for health care\uff1aIntegrate physical sciences, engineering,and biomedicine. Science, 2016, 352(6209):1522\u20141523.<\/span><\/p>\n

[6] Editorials. A community of chemists and biologists. Nature Chemical Biology, 2005, 1(1):3.<\/span><\/p>\n

[7] \u7f8e\u56fd\u79d1\u5b66\u9662\u7814\u7a76\u7406\u4e8b\u4f1a. \u4f1a\u805a\u89c2\uff1a\u63a8\u52a8\u8de8\u5b66\u79d1\u878d\u5408\u2014\u2014\u751f\u547d\u79d1\u5b66\u4e0e\u7269\u8d28\u79d1\u5b66\u548c\u5de5\u7a0b\u5b66\u7b49\u5b66\u79d1\u7684\u8de8\u754c. \u738b\u5c0f\u7406\uff0c\u718a\u71d5\uff0c\u4e8e\u5efa\u8363\uff0c\u8bd1. \u79d1\u5b66\u51fa\u7248\u793e\uff0c\u5317\u4eac\uff1b2015:13.<\/span><\/p>\n

[8] Banks MA. Sizing up big data. Nature Medicine, 2020, 26(1):5\u20146.<\/span><\/p>\n

[9] Regev A, Teichmann SA, Lander ES, et al. The Human Cell Atlas. eLife 2017; 6:e27041.<\/span><\/p>\n

[10] Golub T. Counterpoint: data first. Nature, 2010, 464(7289):679.<\/span><\/p>\n

[11] Ginsberg J, Mohebbi MH, Patel RS, et al. Detecting influenza epidemics using search engine query data. Nature, 2009, 457(7232):1012\u20141014.<\/span><\/p>\n

[12] Lazer DMJ. Pentland A, Watts DJ, et al. Computational social science: Obstacles and opportunities. Science, 2020, 369(6507):1060\u20141062.<\/span><\/p>\n

[13] Editorial. The First Piece of the Pattern. Patterns, 2020, 1, 100020.<\/span><\/p>\n

[14] Urbina-Blanco CA, Jilani SZ, Speight IR, et al. A diverse view of science to catalyse change. Nature Chemistry, 2020, 12(9):773\u2014776.<\/span><\/p>\n

[15] National Academies of Sciences, Engineering, and Medicine 2020. The Endless Frontier: The Next 75 Years in Science. Washington, DC: The National Academies Press. https:\/\/doi.org\/10.17226\/25990.<\/span><\/p>\n

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