{"id":27278,"date":"2021-06-28T20:40:58","date_gmt":"2021-06-28T12:40:58","guid":{"rendered":"https:\/\/swarma.org\/?p=27278"},"modified":"2021-06-28T20:40:58","modified_gmt":"2021-06-28T12:40:58","slug":"sc-gcn%ef%bc%9a%e4%bd%bf%e7%94%a8%e5%9b%be%e5%8d%b7%e7%a7%af%e7%bd%91%e7%bb%9c%e8%bf%9b%e8%a1%8c%e5%8d%95%e7%bb%86%e8%83%9e%e7%bb%84%e5%ad%a6%e6%95%b0%e6%8d%ae%e7%9a%84%e7%9f%a5%e8%af%86%e8%bf%81","status":"publish","type":"post","link":"https:\/\/swarma.org\/?p=27278","title":{"rendered":"sc-GCN\uff1a\u4f7f\u7528\u56fe\u5377\u79ef\u7f51\u7edc\u8fdb\u884c\u5355\u7ec6\u80de\u7ec4\u5b66\u6570\u636e\u7684\u77e5\u8bc6\u8fc1\u79fb"},"content":{"rendered":"<div class='wxsyncmain'>\n<section powered-by=\"xiumi.us\" style=\"letter-spacing: 0.544px;white-space: normal;color: rgb(63, 63, 63);font-family: PingFangSC-light;font-size: 15px;background-color: rgb(255, 255, 255);\" data-mpa-powered-by=\"yiban.io\">\n<section style=\"display: inline-block;width: 661px;vertical-align: top;background-color: rgb(246, 246, 246);\">\n<section>\n<p style=\"text-align: center;\"><img loading=\"lazy\" data-backh=\"268\" data-backw=\"578\" data-ratio=\"0.46444444444444444\"  data-type=\"png\" data-w=\"900\" height=\"279px\" style=\"height: auto;white-space: normal;width: 100%;\" width=\"601\" src=\"\/wp-content\/uploads\/2021\/06\/wxsync-2021-06-0824c31ef35b163b0bd59dc8dc4d0ee9.png\"  \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;letter-spacing: 0.544px;\">\n<section style=\"width: 661px;\">\n<section style=\"padding-right: 3px;float: left;line-height: 1;\">\n<section powered-by=\"xiumi.us\" style=\"text-align: left;\">\n<section style=\"padding-left: 10px;display: inline-block;width: auto;vertical-align: top;min-width: 10%;height: auto;border-left: 3px solid rgb(33, 166, 210);border-bottom-left-radius: 0px;line-height: 0;\">\n<section powered-by=\"xiumi.us\" style=\"transform: translate3d(-13px, 0px, 0px);\">\n<section style=\"display: inline-block;width: 25px;height: 10px;vertical-align: top;overflow: hidden;line-height: 0;border-style: solid solid none;border-width: 3px 3px 2px;border-radius: 0px;border-color: rgb(33, 166, 210) rgb(33, 166, 210) rgb(15, 76, 129);\"><br  \/><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"transform: translate3d(-1px, 0px, 0px);\">\n<section style=\"text-align: justify;color: rgb(33, 166, 210);font-size: 16px;line-height: 1.5;\">\n<p><strong>\u5bfc\u8bed<\/strong><\/p>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"transform: translate3d(-13px, 0px, 0px) rotateX(180deg);\">\n<section style=\"display: inline-block;width: 24px;height: 10px;vertical-align: top;overflow: hidden;line-height: 0;border-style: solid solid none;border-width: 3px 3px 2px;border-radius: 0px;border-color: rgb(33, 166, 210) rgb(33, 166, 210) rgb(15, 76, 129);\"><br  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 4px;padding-left: 4px;clear: right;box-shadow: rgb(0, 0, 0) 0px 0px 0px;min-height: 4.5em !important;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 5px;margin-bottom: 5px;\">\n<section style=\"padding-right: 8px;padding-left: 8px;font-size: 13px;line-height: 2;letter-spacing: 0.544px;\">\n<p style=\"clear: none;\"><strong style=\"letter-spacing: 0.544px;\"><\/strong><strong><span style=\"letter-spacing: 0.544px;\">\u5355\u7ec6\u80de\u7ec4\u5b66\u6570\u636e\uff0c\u4f8b\u5982\u8f6c\u5f55\u7ec4\uff08scRNA-seq\uff09\uff0c\u8868\u89c2\u7ec4\uff08scATAC-seq\uff09\u8bb0\u5f55\u4e86\u7ec6\u80de\u95f4\u7684\u5206\u5b50\u6c34\u5e73\u7684\u5dee\u5f02\u6027\u548c\u76f8\u4e92\u4f5c\u7528\uff0c\u4f7f\u751f\u7269\u5b66\u5bb6\u5f97\u4ee5\u6df1\u5165\u4e86\u89e3\u590d\u6742\u751f\u7269\u751f\u6001\u7cfb\u7edf\u7684\u5355\u4e2a\u7ec6\u80de\u7ec4\u6210\u90e8\u5206\u3002\u968f\u7740\u76f8\u5173\u6570\u636e\u7684\u79ef\u7d2f\uff0c\u5229\u7528\u5df2\u6709\u6807\u8bb0\u6570\u636e\u95f4\u7684\u5173\u7cfb\uff0c\u53bb\u5bf9\u65b0\u6570\u636e\u96c6\u8fdb\u884c\u9884\u6d4b\u6210\u4e3a\u53ef\u80fd\u3002\u4e00\u7bc76\u670822\u65e5\u53d1\u8868\u4e8e<em> Nature Communications<\/em> \u7684\u8bba\u6587\uff0c\u6307\u51fa\u56fe\u5377\u79ef\u795e\u7ecf\u7f51\u7edc\u80fd\u591f\u5728\u8be5\u4efb\u52a1\u4e0a\u53d6\u5f97\u6700\u597d\u7684\u8868\u73b0\u3002<\/span><\/strong><\/p>\n<p style=\"clear: none;\"><strong><span style=\"letter-spacing: 0.544px;\"><br  \/><\/span><\/strong><\/p>\n<p style=\"clear: none;\"><strong><span style=\"letter-spacing: 0.544px;\"><strong style=\"color: rgb(63, 63, 63);font-family: PingFangSC-light;font-size: 13px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(246, 246, 246);\"><span style=\"letter-spacing: 0.544px;\"><strong style=\"letter-spacing: 0.544px;\"><strong style=\"color: rgb(0, 0, 0);font-family: &quot;Helvetica Neue&quot;;letter-spacing: 0.544px;text-align: start;\">\u7814\u7a76\u9886\u57df\uff1a\u751f\u7269\u590d\u6742\u6027\uff0c\u591a\u7ec4\u5b66\uff0c\u56fe\u795e\u7ecf\u7f51\u7edc<\/strong><\/strong><\/span><\/strong><\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;\">\n<section style=\"width: 661px;\">\n<section style=\"clear: both;line-height: 0;\">\n<section style=\"line-height: 0;width: 0px;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;letter-spacing: 0.544px;white-space: normal;color: rgb(63, 63, 63);font-family: PingFangSC-light;font-size: 15px;background-color: rgb(255, 255, 255);text-align: center;\">\n<section style=\"vertical-align: middle;display: inline-block;line-height: 0;\"><img data-ratio=\"0.07314814814814814\"  data-type=\"png\" data-w=\"1080\" style=\"box-sizing: border-box;vertical-align: middle;visibility: visible !important;width: 677px !important;\" src=\"\/wp-content\/uploads\/2021\/06\/wxsync-2021-06-e16cd5b776e38a4f6806c73548bdc7d4.png\"  \/><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 0pt;margin-bottom: 0pt;letter-spacing: 0.544px;white-space: normal;color: rgb(73, 73, 73);line-height: 1.7;font-size: 11pt;font-family: PingFangSC-light;background-color: rgb(255, 255, 255);text-align: right;\">\n<p><span style=\"color: rgb(63, 63, 63);font-size: 13px;letter-spacing: 0.544px;\">\u90ed\u745e\u4e1c<\/span><span style=\"font-size: 13px;letter-spacing: 0.544px;\"><strong style=\"color: rgb(0, 0, 0);\">&nbsp;| \u4f5c\u8005<\/strong><\/span><strong style=\"font-size: 13px;letter-spacing: 0.544px;color: rgb(0, 0, 0);\"><\/strong><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 0pt;margin-bottom: 0pt;letter-spacing: 0.544px;white-space: normal;color: rgb(73, 73, 73);line-height: 1.7;font-size: 11pt;font-family: PingFangSC-light;background-color: rgb(255, 255, 255);text-align: right;\">\n<p><span style=\"color: rgb(63, 63, 63);font-size: 13px;letter-spacing: 0.544px;\"><span style=\"font-family: PingFangSC-light;letter-spacing: 0.544px;text-align: right;background-color: rgb(255, 255, 255);\">\u8d75\u96e8\u4ead<\/span><span style=\"color: rgb(73, 73, 73);font-family: PingFangSC-light;letter-spacing: 0.544px;text-align: right;background-color: rgb(255, 255, 255);\"><strong style=\"color: rgb(0, 0, 0);\">&nbsp;| \u5ba1\u6821<\/strong><\/span><\/span><\/p>\n<p><span style=\"color: rgb(63, 63, 63);font-size: 13px;letter-spacing: 0.544px;\">\u9093\u4e00\u96ea<\/span><span style=\"font-size: 13px;letter-spacing: 0.544px;\"><strong style=\"color: rgb(0, 0, 0);\">&nbsp;| \u7f16\u8f91<\/strong><\/span><\/p>\n<\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;\"><br  \/><\/p>\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><br  \/><\/section>\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages\" data-galleryid=\"\" data-ratio=\"0.48525469168900803\" data-s=\"300,640\"  data-type=\"png\" data-w=\"746\" style=\"\" src=\"\/wp-content\/uploads\/2021\/06\/wxsync-2021-06-fcfd5777276b88226b072335f7d873da.png\"  \/><\/section>\n<blockquote data-type=\"2\" data-url=\"\" data-author-name=\"\" data-content-utf8-length=\"132\" data-source-title=\"\" style=\"letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);\">\n<section style=\"\">\n<section style=\"\">\n<p style=\"color: rgb(63, 63, 63);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;margin-right: 8px;margin-left: 8px;letter-spacing: 0.544px;caret-color: rgb(51, 51, 51);\"><span style=\"font-family: -apple-system, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;text-align: left;letter-spacing: 0.544px;color: rgb(136, 136, 136);\">\u8bba\u6587\u9898\u76ee\uff1a<\/span><br  \/><\/p>\n<p style=\"color: rgba(0, 0, 0, 0.5);font-family: -apple-system, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;margin-right: 8px;margin-left: 8px;line-height: 1.75em;text-align: left;\"><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(136, 136, 136);font-size: 15px;letter-spacing: 0.544px;text-align: left;background-color: rgb(255, 255, 255);\">scGCN is a graph convolutional networks algorithm for knowledge transfer in single cell omics<\/span><\/p>\n<p style=\"color: rgba(0, 0, 0, 0.5);font-family: -apple-system, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;margin-right: 8px;margin-left: 8px;line-height: 1.75em;text-align: left;\"><span style=\"color: rgb(136, 136, 136);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;\">\u8bba\u6587\u5730\u5740\uff1a<\/span><\/p>\n<\/section>\n<\/section>\n<p style=\"margin-right: 8px;margin-left: 8px;white-space: normal;line-height: 1.75em;text-align: left;\"><span style=\"color: rgb(136, 136, 136);letter-spacing: 0.544px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">https:\/\/www.nature.com\/articles\/s41467-021-24172-y<\/span><\/p>\n<\/blockquote>\n<section style=\"line-height: 1.75em;\"><br  \/><\/section>\n<h3 style=\"font-family: -apple-system, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);\">\n<section powered-by=\"xiumi.us\" style=\"letter-spacing: 0.544px;font-family: PingFangSC-light;text-align: right;font-size: 13px;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;letter-spacing: 0.544px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;text-align: center;\">\n<section style=\"display: inline-block;vertical-align: middle;\">\n<section style=\"margin-bottom: -2px;\">\n<section style=\"float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br  \/><\/section>\n<section style=\"float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br  \/><\/section>\n<section style=\"clear: both;line-height: 0;\">\n<section style=\"line-height: 0;width: 0px;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 10px;padding-left: 10px;border-left: 3px solid rgb(33, 166, 210);border-right: 3px solid rgb(33, 166, 210);border-top-color: rgb(33, 166, 210);border-bottom-color: rgb(33, 166, 210);font-size: 16px;color: rgb(0, 0, 0);line-height: 1.4;\">\n<p><strong style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><strong style=\"text-align: left;color: rgb(33, 166, 210);font-family: PingFangSC-light;letter-spacing: 0.544px;\">1. \u5355\u7ec6\u80de\u6570\u636e\u7684\u77e5\u8bc6\u8fc1\u79fb\u4e3a\u4f55\u56f0\u96be<\/strong><\/strong><\/p>\n<\/section>\n<section style=\"margin-top: -2px;\">\n<section style=\"float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br  \/><\/section>\n<section style=\"float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n<p style=\"margin-right: 8px;margin-left: 8px;font-family: -apple-system, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;\"><br  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u6d4b\u5e8f\u5f97\u5230\u7684\u65e0\u6807\u6ce8\u6570\u636e\uff0c\u53ef\u4ee5\u901a\u8fc7\u548c\u5df2\u6709\u7684\u5e26\u6807\u6ce8\u7684\u6570\u636e\u8fdb\u884c\u76f8\u4f3c\u6027\u6bd4\u5bf9\uff0c\u7ed9\u51fa\u6807\u7b7e\uff1b\u6807\u7b7e\u53ef\u4ee5\u662f\u7ec6\u80de\u7c7b\u578b\u3001\u7ec6\u80de\u53d1\u80b2\u4e2d\u7684\u72b6\u6001\u3001\u7ec6\u80de\u529f\u80fd\u6216\u7ec6\u80de\u95f4\u7684\u901a\u4fe1\u6a21\u5f0f\u3002<strong>\u9274\u4e8e\u5355\u7ec6\u80de\u6570\u636e\u7684\u7206\u70b8\u6027\u589e\u957f\uff0c\u8feb\u5207\u9700\u8981\u5229\u7528\u73b0\u6709\u7684\u5177\u6709\u826f\u597d\u6807\u6ce8\u7684\u6570\u636e\u96c6\u4f5c\u4e3a\u53c2\u8003\uff0c\u4ee5\u786e\u4fdd\u6570\u636e\u7684\u6ce8\u91ca\u662f\u53ef\u9760\u5e76\u4e00\u81f4\u7684\u3002<\/strong><\/span><\/section>\n<p><br  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u901a\u8fc7\u5355\u7ec6\u80de\u6570\u636e\u7684\u77e5\u8bc6\u8fc1\u79fb\uff0c\u53ef\u627e\u51fa\u5e26\u6807\u7b7e\u7684\u53c2\u8003\u5355\u7ec6\u80de\u6570\u636e\u4e2d\u4e0d\u540c\u6807\u7b7e\u95f4\u7684\u62d3\u6251\u5173\u7cfb\uff0c\u5e76\u5c06\u6807\u7b7e\u8f6c\u79fb\u5230\u65b0\u751f\u6210\u7684\u6570\u636e\u96c6\u4e2d\uff0c\u4ece\u800c\u4e3a\u65b0\u6570\u636e\u5206\u914d\u7ec6\u80de\u7ea7\u6807\u6ce8\u3002<\/span><\/section>\n<p><br  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u7136\u800c\uff0c\u73b0\u6709\u7684\u6570\u636e\u96c6\u548c\u65b0\u751f\u6210\u7684\u6570\u636e\u96c6\u5f80\u5f80\u662f\u53d6\u6750\u4e8e\u4e0d\u540c\u7684\u7ec4\u7ec7\u548c\u7269\u79cd\u3001\u5728\u4e0d\u540c\u7684\u5b9e\u9a8c\u6761\u4ef6\u4e0b\u3001\u6765\u81ea\u4e0d\u540c\u7684\u5e73\u53f0\u3001\u5305\u542b\u4e0d\u540c\u7684\u7ec4\u5b66\u7c7b\u578b\u3002<strong>\u8fd9\u4f7f\u5f97\u5355\u7ec6\u80de\u9886\u57df\u7684\u77e5\u8bc6\u8fc1\u79fb\u65b9\u6cd5\uff0c\u5fc5\u987b\u80fd\u591f\u5728\u9002\u5e94\u4e0d\u540c\u5b9e\u9a8c\u73af\u5883\u5e26\u6765\u7684\u5dee\u5f02\uff0c\u6355\u6349\u5230\u4e0d\u540c\u751f\u7269\u7ec4\u7ec7\u95f4\u7684\u5185\u5728\u5dee\u5f02\u3002<\/strong><\/span><\/section>\n<p><br  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5e38\u7528\u7684\u5355\u7ec6\u80de\u77e5\u8bc6\u8fc1\u79fb\uff0c\u4f7f\u7528\u7684\u6a21\u578b\u662fSeurat V3\uff0c\u5b83\u4ee5\u67d0\u4e00\u4e2a\u6570\u636e\u4e3a\u951a\u8fdb\u884c\u7684\uff1b\u800c\u53e6\u4e00\u65b9\u6cd5Conos\uff0c\u5219\u662f\u901a\u8fc7\u5c06\u5df2\u77e5\u7684\u65b0\u7684\u6837\u672c\u7684\u6210\u5bf9\u6bd4\u5bf9\uff0c\u751f\u6210\u4e00\u4e2a\u8054\u5408\u56fe\u8868\u793a\uff0c\u5c06\u6807\u7b7e\u4ece\u5df2\u77e5\u6837\u672c\u4f20\u64ad\u5230\u65b0\u6837\u672c\u4e0a\uff0c\u800cCHETAH \u4e3a\u672a\u6807\u6ce8\u6570\u636e\uff0c\u81ea\u4e0a\u800c\u4e0b\u7684\u6784\u5efa\u4e86\u4e00\u4e2a\u5206\u7c7b\u6811\uff0c\u6240\u6709\u8fd9\u4e9b\u65b9\u6cd5\uff0c\u90fd\u53ea\u4ece\u5355\u4e2a\u7ec6\u80de\u4e2d\u63d0\u53d6\u5171\u4eab\u7684\u4fe1\u606f\uff0c\u800c\u5ffd\u7565\u4e86\u7ec6\u80de\u4e4b\u95f4\u7684\u9ad8\u9636\u5173\u7cfb\uff0c\u4ece\u800c\u5bfc\u81f4\u5176\u5206\u7c7b\u6548\u679c\u8f83\u5dee\u3002<\/span><\/section>\n<p><br  \/><\/p>\n<p><br  \/><\/p>\n<h3 style=\"font-family: -apple-system, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);\">\n<section powered-by=\"xiumi.us\" style=\"letter-spacing: 0.544px;font-family: PingFangSC-light;text-align: right;font-size: 13px;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;letter-spacing: 0.544px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;text-align: center;\">\n<section style=\"display: inline-block;vertical-align: middle;\">\n<section style=\"margin-bottom: -2px;\">\n<section style=\"float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br  \/><\/section>\n<section style=\"float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br  \/><\/section>\n<section style=\"clear: both;line-height: 0;\">\n<section style=\"line-height: 0;width: 0px;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 10px;padding-left: 10px;border-left: 3px solid rgb(33, 166, 210);border-right: 3px solid rgb(33, 166, 210);border-top-color: rgb(33, 166, 210);border-bottom-color: rgb(33, 166, 210);font-size: 16px;color: rgb(0, 0, 0);line-height: 1.4;\">\n<p><strong style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><strong style=\"text-align: left;color: rgb(33, 166, 210);font-family: PingFangSC-light;letter-spacing: 0.544px;\">2. scGCN\u662f\u5982\u4f55\u4f7f\u7528\u56fe\u5377\u79ef\u7f51\u7edc\u5f97<\/strong><\/strong><\/p>\n<\/section>\n<section style=\"margin-top: -2px;\">\n<section style=\"float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br  \/><\/section>\n<section style=\"float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n<p style=\"margin-right: 8px;margin-left: 8px;font-family: -apple-system, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;\"><br  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5355\u7ec6\u80de\u7ec4\u5b66\u7684\u6570\u636e\u96c6\uff0c\u90fd\u53ef\u4ee5\u770b\u6210\u662f\u4e00\u4e2a\u4e8c\u7ef4\u77e9\u9635\uff0c\u6a2a\u8f74\u662f\u57fa\u56e0\uff0c\u7eb5\u8f74\u662f\u6807\u7b7e\u3002\u5728\u6570\u636e\u9884\u5904\u7406\u7684\u6b65\u9aa4\u4e2d\uff0c\u7814\u7a76\u4eba\u5458\u5148\u627e\u51fa\u6570\u636e\u4e2d\u5dee\u5f02\u6700\u663e\u8457\u7684\u57fa\u56e0\uff0c\u5bf9\u5df2\u6807\u7b7e\u6570\u636e\u96c6\u548c\u65b0\u6570\u636e\u96c6\u5206\u522b\u6b63\u5219\u5316\u540e\u8fdb\u884c\u6570\u636e\u964d\u7ef4\u3002\u4e4b\u540e\u4f7f\u7528\u5178\u578b\u5173\u8054\u5206\u6790<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08Canonical Correlation Analysis\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\uff0c\u6765\u8ba1\u7b97\u6570\u636e\u96c6\u95f4\u7684\u70b9\u4e0e\u70b9\u4e4b\u95f4\u7684\u76f8\u5173\u6027\uff1b\u4e4b\u540e\u518d\u901a\u8fc7\u5bf9\u76f8\u5173\u77e9\u9635\u8ba1\u7b97\u4e92\u8fd1\u90bb<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08mutual nearest neighbor\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\uff0c\u5b9a\u4e49\u6570\u636e\u96c6\u5185\u90e8\u548c\u8de8\u6570\u636e\u96c6\u7684\u8ddd\u79bb\u3002\u901a\u8fc7\u4e0a\u8ff0\u8fc7\u7a0b\u5f62\u6210\u7684\u56fe\uff0c\u5c31\u662fscGCN\u7684\u6570\u636e\u8f93\u5165<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u4e0b\u56fe\u5de6\u534a\u8fb9\u6240\u793a\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002<\/span><\/section>\n<p><br  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">&nbsp; &nbsp; &nbsp; &nbsp;<\/span><img loading=\"lazy\" data-backh=\"263\" data-backw=\"562\" data-ratio=\"0.46715328467153283\"  data-type=\"png\" data-w=\"685\" height=\"281px\" style=\"height: auto;width: 100%;\" width=\"601\" src=\"\/wp-content\/uploads\/2021\/06\/wxsync-2021-06-924908b514861523b4cb415b08f1a26a.png\"  \/><\/section>\n<p style=\"margin-right: 8px;margin-left: 8px;text-align: center;line-height: 1.5em;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe1. scGCN\u7684\u67b6\u6784\uff0c\u56fe\u4e2d\u539f\u70b9\u4ee3\u8868\u5df2\u6807\u8bb0\u7684\u6570\u636e\uff0c\u4e09\u89d2\u5f62\u7684\u70b9\u4ee3\u8868\u672a\u6807\u8bb0\u7684\u6570\u636e<\/span><\/p>\n<p><br  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u901a\u8fc7\u9884\u5904\u7406\uff0c\u5c06\u7a00\u758f\u7684\u539f\u59cb\u6570\u636e\u96c6\u8f6c\u53d8\u4e3a\u5305\u542b\u8de8\u6570\u636e\u76f8\u5173\u4fe1\u606f\u7684\u6620\u5c04\u56fe\uff0c\u8fd9\u4f7f\u5f97\u5728\u53c2\u8003\u6570\u636e\u96c6\u548c\u672a\u77e5\u6570\u636e\u96c6\u4e4b\u95f4\u5171\u4eab\u4fe1\u606f\uff0c\u8bc6\u522b\u6807\u7b7e\u95f4\u76f8\u4e92\u5173\u7cfb\uff0c\u5e76\u8fc1\u79fb\u5230\u672a\u77e5\u6570\u636e\u96c6\u4e0a\u6210\u4e3a\u53ef\u80fd\u3002\u4e4b\u540e\u901a\u8fc7\u56fe\u5377\u79ef\u795e\u7ecf\u7f51\u7edc\uff0c\u5c06\u5176\u6620\u5c04\u5230\u9690\u7a7a\u95f4\u540e\uff0c\u53ef\u4ee5\u4f7f\u7528\u534a\u76d1\u7763\u5b66\u4e60\u7684\u65b9\u6cd5\uff0c\u53bb\u9884\u6d4b\u672a\u77e5\u6570\u636e\u96c6\u4e0a\u7684\u6807\u7b7e\u3002<\/span><\/section>\n<p><br  \/><\/p>\n<p><br  \/><\/p>\n<h3 style=\"font-family: -apple-system, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);\">\n<section powered-by=\"xiumi.us\" style=\"letter-spacing: 0.544px;font-family: PingFangSC-light;text-align: right;font-size: 13px;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;letter-spacing: 0.544px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;text-align: center;\">\n<section style=\"display: inline-block;vertical-align: middle;\">\n<section style=\"margin-bottom: -2px;\">\n<section style=\"float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br  \/><\/section>\n<section style=\"float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br  \/><\/section>\n<section style=\"clear: both;line-height: 0;\">\n<section style=\"line-height: 0;width: 0px;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 10px;padding-left: 10px;border-left: 3px solid rgb(33, 166, 210);border-right: 3px solid rgb(33, 166, 210);border-top-color: rgb(33, 166, 210);border-bottom-color: rgb(33, 166, 210);font-size: 16px;color: rgb(0, 0, 0);line-height: 1.4;\">\n<p><strong style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><strong style=\"text-align: left;color: rgb(33, 166, 210);font-family: PingFangSC-light;letter-spacing: 0.544px;\">3. scGCN\u7684\u6548\u679c\u660e\u663e\u4f18\u4e8e\u5df2\u6709\u65b9\u6cd5<\/strong><\/strong><\/p>\n<\/section>\n<section style=\"margin-top: -2px;\">\n<section style=\"float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br  \/><\/section>\n<section style=\"float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n<p style=\"margin-right: 8px;margin-left: 8px;font-family: -apple-system, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;\"><br  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u7531\u4e8escGCN \u540c\u65f6\u5229\u7528\u7279\u5f81\u3001\u56fe\u5f62\u7ed3\u6784\u548c\u53c2\u8003\u6807\u7b7e\u6765\u514b\u670d\u6570\u636e\u96c6\u4e4b\u95f4\u7684\u6279\u5904\u7406\u6548\u5e94\u3001\u5e73\u53f0\u5dee\u5f02\u548c\u8de8\u7269\u79cd\u5dee\u5f02\uff0c\u4ee5\u534a\u76d1\u7763\u800c\u4e0d\u662f\u65e0\u76d1\u7763\u7684\u65b9\u5f0f\u5c06\u6807\u7b7e\u4ece\u6807\u8bb0\u6837\u672c\u8f6c\u79fb\u5230\u672a\u6807\u8bb0\u6837\u672c\uff0c\u540c\u65f6\u8003\u8651\u6807\u7b7e\u95f4\u7684\u975e\u7ebf\u6027\u5173\u7cfb\uff0c\u8fd9\u4f7f\u5f97\u672c\u65b9\u6cd5\u66f4\u52a0\u9c81\u68d2\u548c\u9ad8\u6548\u3002<\/span><\/section>\n<p><br  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u9996\u5148\u662f\u5728\u5341\u4e2a\u6807\u51c6\u6570\u636e\u96c6\u4e0a\u6d4b\u8bd5\u4e0d\u540c\u65b9\u6cd5\u7684\u9884\u6d4b\u51c6\u786e\u6027\uff0c\u53ef\u4ee5\u770b\u5230\u76f8\u6bd4\u5df2\u6709\u7684\u65b9\u6cd5\uff0cscGAN\u7684\u51c6\u786e\u6027\u90fd\u4f18\u4e8e\u6216\u7b49\u4e8e\u4e4b\u524d\u7684\u65b9\u6cd5\u3002<\/span><\/section>\n<p style=\"margin-right: 8px;margin-left: 8px;text-align: center;line-height: 1.5em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">&nbsp; &nbsp; &nbsp; &nbsp;<\/span><img loading=\"lazy\" data-backh=\"325\" data-backw=\"562\" data-ratio=\"0.5791666666666667\"  data-type=\"png\" data-w=\"960\" height=\"auto\" style=\"width: 100%;height: auto;\" width=\"960\" src=\"\/wp-content\/uploads\/2021\/06\/wxsync-2021-06-b746928a0bbd48602861c258bc7735e1.png\"  \/><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(136, 136, 136);font-size: 13px;\">\u56fe2. scGCN\u548c\u5df2\u6709\u7684\u65b9\u6cd5\u5728\u9884\u6d4b\u672a\u77e5\u6570\u636e\u6807\u7b7e\u65f6\u7684\u6548\u679c\u5bf9\u6bd4\uff0c\u865a\u7ebf\u4ee3\u8868\u4e24\u8005\u51c6\u786e\u7387\u76f8\u7b49\uff0c\u5de6\u4e0a\u65b9\u610f\u5473\u7740scGCN\u6548\u679c\u66f4\u597d\u3002<\/span><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">&nbsp; &nbsp; &nbsp; &nbsp;<\/span><\/section>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5f53\u53c2\u8003\u6570\u636e\u96c6\u548c\u672a\u77e5\u6570\u636e\u96c6\u6765\u81ea\u4e0d\u540c\u7684\u6d4b\u5e8f\u5e73\u53f0\u65f6\uff0c\u5bf9\u6bd4\u7ed3\u679c\u5982\u4e0b\uff1a<\/span><\/section>\n<p><br  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\"><img loading=\"lazy\" data-backh=\"253\" data-backw=\"562\" data-ratio=\"0.45075757575757575\"  data-type=\"png\" data-w=\"1056\" height=\"auto\" style=\"white-space: normal;width: 100%;height: auto;\" width=\"1056\" src=\"\/wp-content\/uploads\/2021\/06\/wxsync-2021-06-c182927daebecd53a9a68db5a69dd1c1.png\"  \/><\/span><\/section>\n<p style=\"margin-right: 8px;margin-left: 8px;text-align: center;line-height: 1.5em;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe3. \u4e0d\u540c\u6d4b\u5e8f\u5e73\u53f0\u7684\u5bf9\u6bd4\uff0c\u53ef\u89c1scGCN\u7684\u6548\u679c\u8fdc\u597d\u4e8e\u73b0\u6709\u65b9\u6cd5<\/span><\/p>\n<p><br  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u4e0d\u540c\u7269\u79cd\u95f4\u7684\u5355\u7ec6\u80de\u6570\u636e\uff0c\u4e5f\u53ef\u4ee5\u8fdb\u884c\u6807\u7b7e\u8fc1\u79fb\uff0c\u4f8b\u5982\u4f7f\u7528\u5c0f\u9f20\u7684\u80f0\u817a\u5355\u7ec6\u80de\u6570\u636e\uff0c\u9884\u6d4b\u4eba\u7c7b\u7684\u80f0\u817a\u6570\u636e\u7684\u6570\u636e\u7c7b\u578b\uff0c\u5176\u9884\u6d4b\u51c6\u786e\u5ea6\u5982\u4e0b\u56fe\u6240\u793a\uff1a<\/span><\/section>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">&nbsp; &nbsp; &nbsp; &nbsp;<\/span><img loading=\"lazy\" data-backh=\"123\" data-backw=\"562\" data-ratio=\"0.21912114014251782\"  data-type=\"png\" data-w=\"1684\" height=\"auto\" style=\"width: 100%;height: auto;\" width=\"1280\" src=\"\/wp-content\/uploads\/2021\/06\/wxsync-2021-06-2ec99c1d506efbbf0f79feb82ec536dd.png\"  \/><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><\/span><\/section>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe4. \u8de8\u7269\u79cd\u6807\u7b7e\u9884\u6d4b\u7684\u51c6\u786e\u6027\u5bf9\u6bd4<\/span><\/section>\n<p><br  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">scGCN\u8fd8\u53ef\u7528\u4e8e\u5355\u7ec6\u80de\u591a\u7ec4\u5b66\u6570\u636e\u7684\u6574\u5408\uff0c\u4f8b\u5982\u5229\u7528\u8f6c\u5f55\u7ec4\u6570\u636e\u7684\u6807\u7b7e\uff0c\u9884\u6d4b\u65e0\u6807\u6ce8\u7684\u8868\u89c2\u7ec4\u6570\u636e\u5bf9\u5e94\u7684\u6807\u7b7e\uff0c\u8fd9\u662f\u56e0\u4e3a\u867d\u7136\u4e0d\u540c\u7ec4\u5b66\u63cf\u8ff0\u7684\u662f\u7ec6\u80de\u7684\u4e0d\u540c\u751f\u5316\u8fc7\u7a0b\uff0c\u4f46\u4e0d\u540c\u6807\u7b7e\u7684\u7ec6\u80de\u95f4\uff0c\u53d1\u6325\u529f\u80fd\u7684\u57fa\u56e0\u4f1a\u5448\u73b0\u76f8\u4f3c\u7684\u6a21\u5f0f\uff0c\u4ece\u800c\u5728\u9ad8\u7ef4\u6620\u5c04\u540e\u5177\u6709\u76f8\u4f3c\u6027\u3002\u901a\u8fc7\u6570\u636e\u6574\u5408\u540e\uff0c\u8fdb\u884c\u805a\u7c7b\u5206\u6790\uff0c\u4f7f\u7528\u4e24\u79cd\u805a\u7c7b\u8bc4\u4ef7\u65b9\u6cd5\u6279\u6b21\u6548\u5e94\u71b5\u53casilhouette index\uff0c\u53ef\u4ee5\u53d1\u73b0\u4f7f\u7528\u4e0d\u540c\u65b9\u6cd5\u6574\u5408\u540e\u7684\u6570\u636e\u96c6\uff0cscGCN\u6548\u679c\u66f4\u597d\uff0cUMAP\u805a\u7c7b\u540e\uff0c\u4e0d\u540c\u6807\u8bb0\u7684\u6570\u636e\u96c6\u4e5f\u5206\u7684\u66f4\u5f00\u3002<\/span><\/section>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">&nbsp; &nbsp; &nbsp; &nbsp;<\/span><img loading=\"lazy\" data-backh=\"274\" data-backw=\"562\" data-ratio=\"0.486905916585839\"  data-type=\"png\" data-w=\"1031\" height=\"auto\" style=\"width: 100%;height: auto;\" width=\"1031\" src=\"\/wp-content\/uploads\/2021\/06\/wxsync-2021-06-5c69a1fb960500dfc34a1d0d76c9d5e9.png\"  \/><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><\/span><\/section>\n<p style=\"margin-right: 8px;margin-left: 8px;text-align: center;line-height: 1.5em;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe5. \u4e0d\u540c\u7c7b\u578b\u7684\u5355\u7ec6\u80de\u591a\u7ec4\u5b66\u6570\u636e\uff0c\u4f7f\u7528\u4e0d\u540c\u65b9\u6cd5\u8fdb\u884c\u6570\u636e\u6574\u5408\u540e\u7684\u805a\u7c7b\u8bc4\u4ef7\u5bf9\u6bd4<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;text-align: center;line-height: 1.5em;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\"><br  \/><\/span><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><img loading=\"lazy\" data-ratio=\"0.9696969696969697\"  data-type=\"png\" data-w=\"495\" height=\"480\" style=\"height: 480px;text-align: center;white-space: normal;width: 495px;\" width=\"488\" src=\"\/wp-content\/uploads\/2021\/06\/wxsync-2021-06-4f43637e04a9eee5b1a901867286b6b5.png\"  \/><\/span><\/section>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">\u56fe6. \u5355\u7ec6\u80de\u591a\u7ec4\u5b66\u6570\u636e\u6574\u5408\u540e\u7684\u805a\u7c7b\u6548\u679c\u5bf9\u6bd4<\/span><\/section>\n<p><br  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u4ee5\u4e0a\u5b9e\u9a8c\u8bc1\u660e\uff0cscGCN \u5141\u8bb8\u5728\u4e0d\u540c\u7ec4\u7ec7\u3001\u7269\u79cd\u3001\u6d4b\u5e8f\u5e73\u53f0\u4e4b\u95f4\u8fdb\u884c\u6807\u7b7e\u8fc1\u79fb\uff0c\u5e76\u6574\u5408\u591a\u4e2a\u7ec4\u5b66\u7684\u6570\u636e\u96c6\u3002\u5373\u4f7f\u5728\u53c2\u8003\u6570\u636e\u96c6\u7684\u7ec6\u80de\u6570\u5f88\u5c11\u7684\u60c5\u51b5\u4e0b\uff0cscGAN\u4e5f\u80fd\u591f\u7cbe\u786e\u5730\u8fdb\u884c\u6807\u7b7e\u8fc1\u79fb\u3002scGCN \u5728\u8ba1\u7b97\u65f6\u95f4\u548c\u5185\u5b58\u4f7f\u7528\u91cf\u65b9\u9762\u4e0e\u4e3b\u6d41\u65b9\u6cd5 Seurat v3\u76f8\u5f53\uff0c\u53ef\u7528\u4e8e\u5927\u578b\u5355\u7ec6\u80de\u6570\u636e\u96c6\u3002<\/span><\/section>\n<p><br  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u867d\u7136scGCN\u5728\u53ef\u89e3\u91ca\u6027\u4e0a\u6709\u6240\u6b20\u7f3a\uff0c\u4e0d\u80fd\u627e\u51fa\u533a\u5206\u4e0d\u540c\u6807\u7b7e\u7684\u5173\u952e\u57fa\u56e0\uff0c\u5176\u5206\u7c7b\u6548\u679c\u4e5f\u53ef\u8fdb\u4e00\u6b65\u63d0\u5347\u3002\u4f46\u8be5\u65b9\u6cd5\u7684\u6210\u529f\u8bc1\u660e\u4e86\u56fe\u5377\u79ef\u795e\u7ecf\u7f51\u7edc\u8fd9\u4e00\u5feb\u901f\u53d1\u5c55\u7684\u65b9\u6cd5\uff0c\u53ef\u5e94\u7528\u4e8e\u5355\u7ec6\u80de\u7ec4\u5b66\u5206\u6790\u3002<\/span><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: normal;margin-bottom: 10px;\"><span style=\"font-size: 13px;color: rgb(136, 136, 136);\"><br  \/><\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: normal;margin-bottom: 10px;\"><span style=\"font-size: 13px;color: rgb(136, 136, 136);\"><br  \/><\/span><\/p>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);text-align: center;justify-content: center;\">\n<section style=\"display: inline-block;width: auto;vertical-align: top;min-width: 10%;height: auto;box-shadow: rgb(0, 0, 0) 0px 0px 0px;border-bottom: 9px solid rgb(169, 215, 227);border-bottom-right-radius: 0px;\">\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: -15px;\">\n<section style=\"padding-right: 10px;padding-left: 10px;color: rgb(12, 130, 169);font-size: 16px;line-height: 2;letter-spacing: 3px;\">\n<p><strong>\u590d\u6742\u79d1\u5b66\u6700\u65b0\u8bba\u6587<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);\">\n<p><br style=\"color: rgb(63, 63, 63);font-family: PingFangSC-light;font-size: 15px;letter-spacing: 0.544px;\"  \/><\/p>\n<\/section>\n<p style=\"margin-right: 8px;margin-left: 8px;letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u96c6\u667a\u6591\u56fe\u9876\u520a\u8bba\u6587\u901f\u9012\u680f\u76ee\u4e0a\u7ebf\u4ee5\u6765\uff0c\u6301\u7eed\u6536\u5f55\u6765\u81ea<span style=\"font-style: italic;\">Nature\u3001Science<\/span>\u7b49\u9876\u520a\u7684\u6700\u65b0\u8bba\u6587\uff0c\u8ffd\u8e2a\u590d\u6742\u7cfb\u7edf\u3001\u7f51\u7edc\u79d1\u5b66\u3001\u8ba1\u7b97\u793e\u4f1a\u79d1\u5b66\u7b49\u9886\u57df\u7684\u524d\u6cbf\u8fdb\u5c55\u3002\u73b0\u5728\u6b63\u5f0f\u63a8\u51fa\u8ba2\u9605\u529f\u80fd\uff0c\u6bcf\u5468\u901a\u8fc7\u5fae\u4fe1\u670d\u52a1\u53f7\u300c\u96c6\u667a\u6591\u56fe\u300d\u63a8\u9001\u8bba\u6587\u4fe1\u606f\u3002\u626b\u63cf\u4e0b\u65b9\u4e8c\u7ef4\u7801\u5373\u53ef\u4e00\u952e\u8ba2\u9605\uff1a<\/span><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;font-family: -apple-system, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;background-color: rgb(255, 255, 255);text-align: center;\"><img class=\"rich_pages\" data-ratio=\"0.3088962108731466\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1214\" style=\"box-sizing: border-box !important;visibility: visible !important;width: 677px !important;\" src=\"\/wp-content\/uploads\/2021\/06\/wxsync-2021-06-fdadfa689e4fd2c0d00404fdcd994125.png\"  \/><\/p>\n<section powered-by=\"xiumi.us\" style=\"letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);\">\n<p style=\"margin-right: 8px;margin-bottom: 5px;margin-left: 8px;\"><br style=\"letter-spacing: 0.544px;\"  \/><\/p>\n<\/section>\n<p style=\"margin-right: 8px;margin-bottom: 5px;margin-left: 8px;font-family: -apple-system, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;background-color: rgb(255, 255, 255);\"><br  \/><\/p>\n<section powered-by=\"xiumi.us\" style=\"letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;background-color: rgb(255, 255, 255);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">\n<p style=\"margin-right: 8px;margin-bottom: 5px;margin-left: 8px;\"><strong style=\"letter-spacing: 0.544px;color: rgb(0, 0, 0);font-size: 16px;text-align: center;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><strong style=\"text-align: left;color: rgb(33, 166, 210);font-family: PingFangSC-light;letter-spacing: 0.544px;\"><span style=\"font-size: 15px;letter-spacing: 0.544px;\">\u63a8\u8350\u9605\u8bfb<\/span><\/strong><\/strong><\/p>\n<ul class=\"list-paddingleft-2\" style=\"list-style-type: disc;\">\n<li style=\"font-weight: bold;\">\n<section style=\"margin-right: 8px;margin-left: 8px;margin-bottom: 10px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247488516&amp;idx=1&amp;sn=4b9632eacde5b34d0a1a08fa0aeda82d&amp;chksm=e8944e89dfe3c79f9b7f59799de567feb3f391ae877894c3bbdb8683af73ad72b1fcd4354431&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" style=\"text-decoration: underline;\" data-linktype=\"2\" rel=\"noopener noreferrer\">\u6df1\u5ea6\u5b66\u4e60\u65b0\u661f | \u56fe\u5377\u79ef\u795e\u7ecf\u7f51\u7edc\uff08GCN\uff09\u6709\u591a\u5f3a\u5927\uff1f<\/a><\/section>\n<\/li>\n<li style=\"font-weight: bold;\">\n<section style=\"margin-right: 8px;margin-left: 8px;margin-bottom: 10px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247500502&amp;idx=3&amp;sn=1594d1cfd152e95512485050353e77e7&amp;chksm=e897985bdfe0114d4559439b2d268bfa25d7baaff231af81a76bd266f026b653f3739f57c086&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" style=\"text-decoration: underline;\" data-linktype=\"2\" rel=\"noopener noreferrer\">\u56fe\u534a\u76d1\u7763\u5206\u7c7b\u7684\u76f8\u53d8\u548c\u4f18\u5316\u7b97\u6cd5\uff1a\u4ece\u4fe1\u5ff5\u4f20\u64ad\u5230\u5377\u79ef\u795e\u7ecf\u7f51\u7edc | \u7f51\u7edc\u79d1\u5b66\u8bba\u6587\u901f\u901223\u7bc7<\/a><br  \/><\/section>\n<\/li>\n<li>\n<section style=\"margin-right: 8px;margin-left: 8px;margin-bottom: 10px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247561270&amp;idx=1&amp;sn=e4d4454ba314931b5121332a0501280d&amp;chksm=e896aabbdfe123ad0014213b46a472704c4fd2f6c3a90f77b038353d12d41fc400474acbf193&amp;scene=21#wechat_redirect\" data-itemshowtype=\"0\" tab=\"innerlink\" style=\"text-decoration: underline;\" data-linktype=\"2\" rel=\"noopener noreferrer\"><strong><span style=\"font-size: 14px;\">\u52a0\u5165\u96c6\u667a\uff0c\u4e00\u8d77\u590d\u6742\uff01<\/span><\/strong><\/a><br  \/><\/section>\n<\/li>\n<\/ul>\n<p style=\"margin-right: 8px;margin-bottom: 5px;margin-left: 8px;\"><br  \/><\/p>\n<\/section>\n<p style=\"letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;background-color: rgb(255, 255, 255);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><br  \/><\/p>\n<p style=\"letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;background-color: rgb(255, 255, 255);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><strong style=\"letter-spacing: 0.544px;font-size: 15px;text-align: left;color: rgb(255, 255, 255);font-family: PingFangSC-light;\"><span style=\"background-color: rgb(12, 130, 169);\">\u70b9\u51fb\u201c\u9605\u8bfb\u539f\u6587\u201d\uff0c<strong style=\"letter-spacing: 0.544px;\">\u8ffd\u8e2a\u590d\u6742\u79d1\u5b66\u9876\u520a\u8bba\u6587<\/strong><\/span><\/strong><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5bfc\u8bed \u5355\u7ec6\u80de\u7ec4\u5b66\u6570\u636e\uff0c\u4f8b\u5982\u8f6c\u5f55\u7ec4\uff08scRNA-seq\uff09\uff0c\u8868\u89c2\u7ec4\uff08scATAC-seq\uff09\u8bb0\u5f55\u4e86\u7ec6\u80de\u95f4\u7684\u5206\u5b50\u6c34\u5e73\u7684\u5dee\u5f02\u6027\u548c\u76f8\u4e92\u4f5c\u7528\uff0c\u4f7f\u751f\u7269\u5b66\u5bb6\u5f97\u4ee5\u6df1\u5165\u4e86\u89e3\u590d\u6742\u751f\u7269\u751f\u6001\u7cfb\u7edf\u7684\u5355\u4e2a\u7ec6\u80de\u7ec4\u6210\u90e8\u5206\u3002\u968f\u7740\u76f8\u5173\u6570\u636e\u7684\u79ef\u7d2f\uff0c\u5229\u7528\u5df2\u6709\u6807\u8bb0\u6570\u636e\u95f4\u7684\u5173\u7cfb\uff0c\u53bb\u5bf9\u65b0\u6570\u636e\u96c6\u8fdb\u884c\u9884\u6d4b\u6210\u4e3a\u53ef\u80fd\u3002\u4e00\u7bc76\u670822\u65e5\u53d1\u8868\u4e8e Nature C&#8230;<\/p>\n","protected":false},"author":1,"featured_media":27269,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"special":[],"_links":{"self":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/27278"}],"collection":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=27278"}],"version-history":[{"count":0,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/27278\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/media\/27269"}],"wp:attachment":[{"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=27278"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=27278"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=27278"},{"taxonomy":"special","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fspecial&post=27278"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}