{"id":32881,"date":"2022-03-04T13:09:53","date_gmt":"2022-03-04T05:09:53","guid":{"rendered":"https:\/\/swarma.org\/?p=32881"},"modified":"2022-03-04T13:09:53","modified_gmt":"2022-03-04T05:09:53","slug":"nat-commun-%e9%80%9f%e9%80%92%ef%bc%9a%e8%99%9a%e6%8b%9f%e9%a2%85%e5%86%85%e8%84%91%e7%94%b5%e4%b8%8e%e7%a5%9e%e7%bb%8f%e5%8a%a8%e5%8a%9b%e5%ad%a6%e6%a8%a1%e5%9e%8b","status":"publish","type":"post","link":"https:\/\/swarma.org\/?p=32881","title":{"rendered":"Nat. Commun. \u901f\u9012\uff1a\u865a\u62df\u9885\u5185\u8111\u7535\u4e0e\u795e\u7ecf\u52a8\u529b\u5b66\u6a21\u578b"},"content":{"rendered":"
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Virtual intracranial EEG signals reconstructed from MEG with potential for epilepsy surgery<\/span><\/h1>\n
\u8bba\u6587\u5730\u5740\uff1ahttps:\/\/www.nature.com\/articles\/s41467-022-28640-x<\/span><\/section>\n<\/section>\n<\/section>\n<\/blockquote>\n

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\u52a8\u529b\u5b66\u7f51\u7edc\u6a21\u578b\u662f\u63a2\u7d22\u590d\u6742\u795e\u7ecf\u7cfb\u7edf\u6f5c\u5728\u673a\u5236\u7684\u6709\u529b\u5de5\u5177[1,6-18]\u3002\u7136\u800c\uff0c\u5f53\u524d\u7684\u7814\u7a76\u4e3b\u8981\u4f9d\u8d56\u8bb0\u5f55\u76ae\u5c42\u6d3b\u52a8\u7684\u4fb5\u5165\u6027\u9885\u5185\u7535\u751f\u7406\u6280\u672f, \u5305\u62ec\u690d\u5165\u52a8\u7269\u6216\u766b\u75eb\u75c5\u4eba\u7684\u9885\u5185\u8111\u7535\u56fe<\/span>\uff08Intracranial Electroencephalography, iEEG\uff09<\/span>\u3002\u7531\u4e8e\u9885\u5185\u8111\u7535\u56fe\u6700\u5927\u4ec5\u80fd\u8986\u76d610%\u7684\u5927\u8111\u533a\u57df[19]\u4e14\u98ce\u9669\u6781\u9ad8<\/span>\uff08\u5305\u62ec\u9885\u5185\u611f\u67d3\u4e0e\u51fa\u8840\uff09<\/span>[20-21]\uff0c\u5df2\u6709\u7684\u7814\u7a76\u53ea\u80fd\u8003\u8651\u90e8\u5206\u8111\u533a\u7684\u751f\u7406\u3001\u75c5\u7406\u6d3b\u52a8\uff0c\u5728\u7a7a\u95f4\u4e0a\u6709\u6781\u5927\u5c40\u9650\u6027[19]\u3002\u6b64\u5916\uff0c\u83b7\u53d6\u4fb5\u5165\u6027\u6570\u636e\u7684\u6210\u672c\u9ad8<\/span>\uff08\u5355\u6839\u7535\u6781\u6210\u672c\u63a5\u8fd11\u4e07\u4eba\u6c11\u5e01\uff09<\/span>\uff0c\u5e76\u4e14\u53ea\u80fd\u4ece\u60a3\u75c5\u7684\u4eba\u8111\u83b7\u53d6\u3002<\/span><\/p>\n

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Cook & Plummer\u56e2\u961f<\/span>\uff08\u66f9\u6dfc\u535a\u58eb\u4e3a\u7b2c\u4e00\u4f5c\u8005\uff09<\/span>\u7814\u53d1\u4e86\u865a\u62df\u9885\u5185\u8111\u7535\u56fe\u6280\u672f<\/span>\uff08Virtual intracranial Electroencephalography, ViEEG\uff09<\/span>\uff0c\u5728\u766b\u75eb\u75c5\u4eba\u672f\u524d\u6838\u78c1\u5171\u632f\u8111\u7ed3\u6784\u5f71\u50cf\u4e0a\u5b9a\u4e49\u4e00\u7cfb\u5217\u865a\u62df\u7535\u6781<\/span>\uff08virtual electrodes\uff09<\/span>\u3002\u7136\u540e\u4f7f\u7528\u57fa\u4e8ebeamformers\u7684\u6e90\u4fe1\u53f7\u91cd\u5efa\u6280\u672f\u4e0e\u766b\u75eb\u53d1\u4f5c\u671f\u8111\u78c1\u56fe\u4fe1\u53f7<\/span>\uff08Ictal MEG signals \u56fe1\uff09<\/span>\uff0c\u5728\u865a\u62df\u7535\u6781\u4f4d\u7f6e\u91cd\u5efa\u766b\u75eb\u53d1\u4f5c\u6e90\u4fe1\u53f7<\/span>\uff08Ictal ViEEG signals \u56fe1\uff09<\/span>\u3002\u901a\u8fc7\u8be5\u6280\u672f\u91cd\u5efa\u7684\u8111\u78c1\u56fe\u6e90\u4fe1\u53f7\u4e0e\u540c\u4e00\u4e2a\u75c5\u4eba\u8bb0\u5f55\u7684\u9885\u5185\u7535\u751f\u7406\u53d1\u4f5c\u4fe1\u53f7\u5728\u7a7a\u95f4\u548c\u4fe1\u53f7\u6ce2\u5f62\u4e0a\u6709\u9ad8\u76f8\u4f3c\u5ea6<\/span>\uff08\u5982\u56fe2\u6240\u793a\uff09<\/span>\u3002\u7814\u7a76\u65b9\u6cd5\u4e0e\u6d41\u7a0b\u5982\u56fe1\u6240\u793a\u3002<\/span><\/p>\n


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\u56fe1. \u865a\u62df\u9885\u5185\u8111\u7535\u56fe\u6280\u672f\u4e0e\u795e\u7ecf\u52a8\u529b\u5b66\u6a21\u578b\u793a\u610f\u56fe<\/span><\/section>\n


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\u56fe2. ViEEG seizure\u4e0eiEEG seizure\u7684\u7a7a\u95f4\u4f4d\u7f6e\u4e0e\u6ce2\u5f62\u6bd4\u8f83\u793a\u610f\u56fe<\/span><\/p>\n


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2. Breakspear, M. & Stam, C. J. Dynamics of a neural system with a multiscale architecture. Philos. Trans. R. Soc. Lond. B Biol. Sci. 360, 1051\u20131074 (2005).<\/span><\/p>\n

3. Stam, C. J. Modern network science of neurological disorders. Nat. Rev. Neurosci. 15, 683\u2013695 (2014).<\/span><\/p>\n

4. Fornito, A., Zalesky, A. & Breakspear, M. The connectomics of brain disorders. Nat. Rev. Neurosci. 16, 159\u2013172 (2015).<\/span><\/p>\n

5. Tong, F. & Pratte, M. S. Decoding patterns of human brain activity. Annu. Rev. Psychol. 63, 483\u2013509 (2012).<\/span><\/p>\n

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8. Wendling, F., Bellanger, J. J., Bartolomei, F. & Chauvel, P. Relevance of nonlinear lumped-parameter models in the analysis of depth-EEG epileptic signals. Biol. Cybern. 83, 367\u2013378 (2000).<\/span><\/p>\n

9. David, O. & Friston, K. J. A neural mass model for MEG\/EEG: coupling and neuronal dynamics. Neuroimage 20, 1743\u20131755 (2003).<\/span><\/p>\n

10. Robinson, P. A., Rennie, C. J. & Rowe, D. L. Dynamics of large-scale brain activity in normal arousal states and epileptic seizures. Phys. Rev. E 65, 041924 (2002).<\/span><\/p>\n

11. Freyer, F. et al. Biophysical mechanisms of multistability in resting-state cortical rhythms. J. Neurosci. 31, 6353\u20136361 (2011).<\/span><\/p>\n

12. Wendling, F., Bartolomei, F., Bellanger, J. J. & Chauvel, P. Epileptic fast activity can be explained by a model of impaired GABAergic dendritic inhibition. Eur. J. Neurosci. 15, 1499\u20131508 (2002).<\/span><\/p>\n

13. Breakspear, M. et al. A unifying explanation of primary generalized seizures through nonlinear brain modeling and bifurcation analysis. Cereb. Cortex 16, 1296\u20131313 (2006).<\/span><\/p>\n

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16. Proix, T., Bartolomei, F., Guye, M. & Jirsa, V. K. Individual brain structure and modelling predict seizure propagation. Brain 140, 641\u2013654 (2017).<\/span><\/p>\n

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20. Nagahama, Y. et al. Intracranial EEG for seizure focus localization: evolving techniques, outcomes, complications, and utility of combining surface and depth electrodes. J. Neurosurg. 130, 1180\u20131192 (2019).<\/span><\/p>\n

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22. Lopes da Silva, F. EEG and MEG: relevance to neuroscience. Neuron 80, 1112\u20131128 (2013).<\/span><\/p>\n

23. Schoffelen, J. M. & Gross, J. Source connectivity analysis with MEG and EEG. Hum. Brain Mapp. 30, 1857\u20131865 (2009).<\/span><\/p>\n

24. Hari, R. et al. IFCN-endorsed practical guidelines for clinical magnetoencephalography (MEG). Clin. Neurophysiol. 129, 1720\u20131747 (2018).<\/span><\/p>\n

25. Hamalainen, M. S. Magnetoencephalography: a tool for functional brain imaging. Brain Topogr. 5,95\u2013102 (1992).<\/span><\/p>\n

26. Plummer, C., Harvey, A. S. & Cook, M. EEG source localization in focal epilepsy: where are we now? Epilepsia 49, 201\u2013218 (2008).<\/span><\/p>\n

27. He, K. et al. A high-performance compact magnetic shield for optically pumped magnetometer-based magnetoencephalography. Rev. Sci. Instrum. 90, 064102 (2019).<\/span><\/p>\n

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29. Baillet, S. et al. Evaluation of inverse methods and head models for EEG source localization using a human skull phantom. Phys. Med. Biol. 46,77\u201396 (2001) .<\/span><\/p>\n

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32. Kwan, P. & Brodie, M. J. Early identi\ufb01cation of refractory epilepsy. N. Engl. J. Med. 342, 314\u2013319 (2000).<\/span><\/p>\n

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34. Vakharia, V. N. et al. Getting the best outcomes from epilepsy surgery. Ann. Neurol. 83, 676\u2013690 (2018).<\/span><\/p>\n

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36. Duncan, J. S., Winston, G. P., Koepp, M. J. & Ourselin, S. Brain imaging in the assessment for epilepsy surgery. Lancet Neurol. 15, 420\u2013433 (2016)<\/span><\/p>\n

37. Lopes, M. A. et al. An optimal strategy for epilepsy surgery: disruption of the rich-club? PLoS Comput. Biol. 13, e1005637 (2017).<\/span><\/p>\n


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\u8be6\u60c5\u8bf7\u89c1\uff1a<\/span>
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\u63a8\u8350\u9605\u8bfb<\/span><\/strong><\/strong><\/p>\n