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\u53e6\u4e00\u79cd\u65b9\u6cd5\u662f\uff0c\u521b\u9020\u4e00\u4e2a\u7c7b\u4f3c\u4e8e\u4eba\u4eec\u8ba4\u4e3a\u5728\u8fdb\u5316\u8fc7\u7a0b\u4e2d\u5b58\u5728\u7684\uff0c\u79f0\u4e3a\u539f\u59cb\u6c64\u7684\u72b6\u6001\u7684\u539f\u59cb\u7ec6\u80de\u3002\u5404\u79cdRNA\u805a\u5408\u7269\u53ef\u4ee5\u88ab\u5305\u5c01\u5728\u56ca\u6ce1\u4e2d\uff0c\u5728\u5982\u6b64\u5c0f\u7684\u8fb9\u754c\u6761\u4ef6\u4e0b\uff0c\u5c06\u8fdb\u884c\u5316\u5b66\u53cd\u5e94\u6d4b\u8bd5\u3002<\/span><\/p>\n


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\u539f\u59cb\u7ec6\u80de\u7684\u7814\u7a76\u5f15\u8d77\u4e86\u4e89\u8bae\u548c\u53cd\u5bf9\u610f\u89c1\uff0c\u5305\u62ec\u5bf9\u201d\u4eba\u5de5\u751f\u547d\u201d\u6a21\u7cca\u5b9a\u4e49\u7684\u6279\u8bc4\u3002\u5c3d\u7ba1\u5bf9\u539f\u7ec6\u80de\u6700\u666e\u904d\u7684\u62c5\u5fe7\u662f\u5b83\u4eec\u901a\u8fc7\u4e0d\u53d7\u63a7\u5236\u7684\u590d\u5236\u5bf9\u4eba\u7c7b\u5065\u5eb7\u548c\u73af\u5883\u7684\u6f5c\u5728\u5a01\u80c1\uff0c\u4f46\u521b\u9020\u4e00\u4e2a\u57fa\u672c\u7684\u751f\u547d\u5355\u4f4d\u6700\u7d27\u8feb\u7684\u95ee\u9898\u662f\u4f26\u7406\u3002<\/span><\/p>\n


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\u56fd\u9645\u7814\u7a76<\/span><\/strong><\/span><\/h3>\n

2010\u5e74\u4ee3\u4e2d\u671f\uff0c\u7814\u7a76\u754c\u5f00\u59cb\u8ba4\u8bc6\u5230\u6709\u5fc5\u8981\u7edf\u4e00\u4eba\u5de5\u5408\u6210\u7ec6\u80de\u7684\u7814\u7a76\u9886\u57df\uff0c\u627f\u8ba4\u4ece\u975e\u751f\u7269\u6210\u5206\u6784\u5efa\u4e00\u4e2a\u5b8c\u6574\u751f\u7269\u4f53\u7684\u4efb\u52a1\u8d85\u51fa\u4e86\u4e00\u4e2a\u56fd\u5bb6\u7684\u8d44\u6e90\u8303\u56f4\u3002<\/span><\/p>\n


2017\u5e74\uff0c\u56fd\u9645\u4e0a\u5927\u89c4\u6a21\u7684\u4eba\u5de5\u5408\u6210\u6d3b\u7ec6\u80de\u5efa\u8bbe\u7814\u7a76\u5408\u4f5c\u6b63\u5f0f\u542f\u52a8\uff0c\u968f\u540e\u82e5\u5e72\u56fd\u5bb6\u4e5f\u5f00\u5c55\u4e86\u56fd\u5bb6\u95f4\u7684\u5408\u6210\u7ec6\u80de\u5408\u4f5c\u7814\u7a76\u3002\u8fd9\u4e9b\u5168\u56fd\u6027\u7ec4\u7ec7\u5305\u62ec FabriCell\u3001 MaxSynBio\u548c BaSyC\u3002\u6b27\u6d32\u5408\u6210\u7ec6\u80de\u7684\u52aa\u529b\u57282019\u5e74\u88ab\u7edf\u4e00\u4e3a SynCellEU \u5021\u8bae\u3002<\/span><\/p>\n


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\u6765\u81ea\u514b\u83b1\u683c\u00b7\u51e1\u7279\u7814\u7a76\u6240 J. Craig Venter Institute\u7684\u6210\u5458\u4f7f\u7528\u4e86\u4e00\u79cd\u81ea\u4e0a\u800c\u4e0b\u7684\u8ba1\u7b97\u65b9\u6cd5\uff0c\u5c06\u6d3b\u751f\u7269\u4f53\u4e2d\u7684\u57fa\u56e0\u6572\u9664\u81f3\u6700\u5c0f\u7684\u4e00\u7ec4\u57fa\u56e0\u30022010\u5e74\uff0c\u7814\u7a76\u5c0f\u7ec4\u5229\u7528\u4eba\u5de5\u5408\u6210\u4e2d\u88ab\u8ba4\u4e3a\u662f\u751f\u547d\u6700\u4f4e\u8981\u6c42\u7684 DNA\uff0c\u6210\u529f\u5730\u521b\u9020\u4e86\u4e00\u4e2a\u4e00\u682a\u80fd\u590d\u5236\u7684\u4e1d\u72b6\u652f\u539f\u4f53(\u652f\u539f\u4f53\u5b9e\u9a8c\u5ba4) \uff0c\u8fd9\u79cd DNA \u88ab\u63d2\u5165\u5230\u4e00\u4e2a\u57fa\u56e0\u7ec4\u7a7a\u767d\u7684\u7ec6\u83cc\u4e2d\u3002\u4eba\u4eec\u5e0c\u671b\uff0c\u81ea\u4e0a\u800c\u4e0b\u7684\u751f\u7269\u5408\u6210\u8fc7\u7a0b\u5c06\u80fd\u591f\u63d2\u5165\u65b0\u7684\u57fa\u56e0\uff0c\u8fd9\u4e9b\u57fa\u56e0\u5c06\u53d1\u6325\u6709\u5229\u7684\u4f5c\u7528\uff0c\u4f8b\u5982\u4ea7\u751f\u6c22\u6c14\u4f5c\u4e3a\u71c3\u6599\u6216\u5728\u5927\u6c14\u4e2d\u6355\u83b7\u8fc7\u91cf\u7684\u4e8c\u6c27\u5316\u78b3\u3002\u65e0\u6570\u7684\u8c03\u8282\u3001\u65b0\u9648\u4ee3\u8c22\u548c\u4fe1\u53f7\u7f51\u7edc\u6ca1\u6709\u88ab\u5b8c\u5168\u5730\u8868\u73b0\uff0c\u8fd9\u4e9b\u81ea\u4e0a\u800c\u4e0b\u7684\u65b9\u6cd5\u5bf9\u4e8e\u7406\u89e3\u57fa\u672c\u7684\u5206\u5b50\u8c03\u63a7\u6709\u5c40\u9650\u6027\uff0c\u56e0\u4e3a\u5bbf\u4e3b\u751f\u7269\u6709\u4e00\u4e2a\u590d\u6742\u7684\u548c\u4e0d\u5b8c\u5168\u786e\u5b9a\u7684\u5206\u5b50\u7ec4\u6210\u30022019\u5e74\uff0c\u652f\u539f\u4f53 Syn3.0\u7ec6\u80de\u4e2d\u6240\u6709\u901a\u8def\u7684\u5b8c\u6574\u8ba1\u7b97\u6a21\u578b\u88ab\u53d1\u8868\uff0c\u8fd9\u662f\u7b2c\u4e00\u4e2a\u5b8c\u6574\u7684\u5fae\u751f\u7269\u6d3b\u4f53\u7845\u6a21\u578b\u3002<\/span><\/p>\n


\u5927\u516c\u53f8\u5df2\u7ecf\u5728\u751f\u7269\u9886\u57df\u6295\u5165\u4e86\u5927\u91cf\u8d44\u91d1\uff0c\u6bd4\u5982\u4e0e\u5408\u6210\u57fa\u56e0\u516c\u53f8\u5408\u4f5c\u7684\u57c3\u514b\u68ee\u7f8e\u5b5a\u516c\u53f8 ExxonMobil\u3001\u514b\u96f7\u683c\u00b7\u6587\u7279 Craig Venter\u7684\u5f00\u53d1\u85fb\u7c7b\u71c3\u6599\u7684\u751f\u7269\u5408\u6210\u516c\u53f8\u3002<\/span><\/p>\n


\u622a\u81f32016\u5e74\uff0c\u751f\u6b96\u652f\u539f\u4f53 Mycoplasma genitalium\u662f\u552f\u4e00\u4e00\u79cd\u53ef\u4ee5\u4f5c\u4e3a\u6700\u5c0f\u7ec6\u80de\u5de5\u7a0b\u8d77\u70b9\u7684\u6709\u673a\u4f53\uff0c\u56e0\u4e3a\u5b83\u62e5\u6709\u5df2\u77e5\u6700\u5c0f\u7684\u53ef\u4ee5\u5728\u5b9e\u9a8c\u5ba4\u6761\u4ef6\u4e0b\u57f9\u80b2\u7684\u57fa\u56e0\u7ec4; \u91ce\u751f\u578b\u54c1\u79cd\u6709482\u4e2a\u57fa\u56e0\uff0c\u53bb\u9664\u6b63\u597d100\u4e2a\u88ab\u8ba4\u4e3a\u975e\u5fc5\u9700\u7684\u57fa\u56e0\uff0c\u5c31\u80fd\u57f9\u80b2\u51fa\u751f\u957f\u901f\u5ea6\u63d0\u9ad8\u7684\u53ef\u5b58\u6d3b\u83cc\u682a\u3002\u51cf\u5c11\u57fa\u56e0\u7ec4\u7684\u5927\u80a0\u6746\u83cc\u662f\u66f4\u6709\u7528\u7684\uff0c\u800c\u4e14\u5df2\u7ecf\u5f00\u53d1\u51fa\u53bb\u9664\u4e8615% \u7684\u57fa\u56e0\u7ec4\u7684\u53ef\u751f\u5b58\u83cc\u682a\u3002<\/span><\/p>\n


\u901a\u8fc7\u5c06\u4e00\u4e2a\u5b8c\u5168\u5408\u6210\u7684\u57fa\u56e0\u7ec4\u5f15\u5165\u5230\u57fa\u56e0\u7ec4\u4e0a\u7a7a\u51fa\u7684\u5bbf\u4e3b\u7ec6\u80de\u4e2d\uff0c\u5373\u521b\u9020\u51fa\u4e86\u4e00\u79cd\u4eba\u5de5\u7ec6\u80de\u3002\u5c3d\u7ba1\u7531\u4e8e\u5bbf\u4e3b\u7ec6\u80de\u7684\u7ec6\u80de\u8d28\u6210\u5206\u548c\u7ec6\u80de\u819c\u88ab\u4fdd\u7559\u4e0b\u6765\u800c\u4e0d\u5b8c\u5168\u662f\u4eba\u5de5\u5408\u6210\u7684\uff0c\u4f46\u8be5\u5de5\u7a0b\u7ec6\u80de\u5904\u4e8e\u5408\u6210\u57fa\u56e0\u7ec4\u7684\u63a7\u5236\u4e4b\u4e0b\uff0c\u80fd\u591f<\/span>\u81ea\u590d\u5236<\/span>\u3002<\/span><\/p>\n


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\u6807\u51c6\u4eba\u5de5\u7ec6\u80de(\u4e0a)\u548c\u836f\u7269\u4f20\u9012\u4eba\u5de5\u7ec6\u80de(\u4e0b)\u3002<\/span><\/p>\n


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20\u4e16\u7eaa60\u5e74\u4ee3\uff0cThomas Chang\u7814\u5236\u51fa\u4e86\u5fae\u80f6\u56ca\uff0c\u7531\u4e8e\u5b83\u4eec\u662f\u7531\u4eba\u9020\u6750\u6599\u5236\u6210\u7684\u7ec6\u80de\u5927\u5c0f\u7684\u9694\u5ba4\uff0c\u540e\u6765\u4ed6\u79f0\u4e4b\u4e3a\u201c\u4eba\u5de5\u7ec6\u80de\u201d\u3002\u8fd9\u4e9b\u7ec6\u80de\u7531\u5c3c\u9f99\u3001\u706b\u68c9\u80f6\u6216\u4ea4\u8054\u86cb\u767d\u8d28\u7684\u8d85\u8584\u819c\u7ec4\u6210\uff0c\u5176\u534a\u900f\u6027\u4f7f\u5f97\u5c0f\u5206\u5b50\u53ef\u4ee5\u6269\u6563\u8fdb\u51fa\u7ec6\u80de\u3002\u8fd9\u4e9b\u7ec6\u80de\u662f\u5fae\u7c73\u5927\u5c0f\uff0c\u542b\u6709\u7ec6\u80de\uff0c\u9176\uff0c\u8840\u7ea2\u86cb\u767d\uff0c\u78c1\u6027\u6750\u6599\uff0c\u5438\u9644\u5242\u548c\u86cb\u767d\u8d28\u3002<\/span>
<\/p>\n


\u540e\u6765\u4eba\u5de5\u7ec6\u80de\u7684\u5c3a\u5bf8\u4ece\u767e\u5fae\u7c73\u5230\u7eb3\u7c73\u4e0d\u7b49\uff0c\u53ef\u4ee5\u643a\u5e26\u5fae\u751f\u7269\u3001\u75ab\u82d7\u3001\u57fa\u56e0\u3001\u836f\u7269\u3001\u6fc0\u7d20\u548c\u591a\u80bd\u3002\u4eba\u5de5\u7ec6\u80de\u7684\u7b2c\u4e00\u6b21\u4e34\u5e8a\u5e94\u7528\u662f\u4ee5\u836f\u7528\u6d3b\u6027\u70ad\u4e3a\u5305\u56ca\u8fdb\u884c\u8840\u6db2\u704c\u6d41\u3002<\/span><\/p>\n


\u572820\u4e16\u7eaa70\u5e74\u4ee3\uff0c\u7814\u7a76\u4eba\u5458\u80fd\u591f\u5c06\u9176\u3001\u86cb\u767d\u8d28\u548c\u6fc0\u7d20\u5f15\u5165\u5230\u53ef\u751f\u7269\u964d\u89e3\u7684\u5fae\u80f6\u56ca\u4e2d\uff0c\u540e\u6765\u8fd9\u79cd\u5fae\u80f6\u56ca\u5728\u8bf8\u5982\u83b1\u5e0c\uff0d\u5c3c\u4ea8\u6c0f\u75c7\u5019\u7fa4 Lesch\u2013Nyhan syndrome\u4e4b\u7c7b\u7684\u75be\u75c5\u4e2d\u5f97\u5230\u4e34\u5e8a\u5e94\u7528\u3002\u5c3d\u7ba1Thomas Chang\u6700\u521d\u7684\u7814\u7a76\u96c6\u4e2d\u5728\u4eba\u5de5\u7ea2\u7ec6\u80de\u4e0a\uff0c\u4f46\u76f4\u523020\u4e16\u7eaa90\u5e74\u4ee3\u4e2d\u671f\uff0c\u624d\u51fa\u73b0\u4e86\u53ef\u751f\u7269\u964d\u89e3\u7684\u4eba\u5de5\u7ea2\u7ec6\u80de\u30021994\u5e74\uff0c\u751f\u7269\u7ec6\u80de\u5c01\u88c5\u7684\u4eba\u5de5\u7ec6\u80de\u9996\u6b21\u5728\u4e34\u5e8a\u4e0a\u7528\u4e8e\u6cbb\u7597\u7cd6\u5c3f\u75c5\u60a3\u8005\uff0c\u6b64\u540e\uff0c\u5176\u4ed6\u7c7b\u578b\u7684\u7ec6\u80de\uff0c\u5982\u809d\u7ec6\u80de\u3001\u6210\u4f53\u5e72\u7ec6\u80de\u548c\u57fa\u56e0\u5de5\u7a0b\u7ec6\u80de\u5df2\u88ab\u5c01\u88c5\uff0c\u5e76\u6b63\u5728\u7814\u7a76\u7528\u4e8e\u7ec4\u7ec7\u518d\u751f\u3002<\/span><\/p>\n


<\/p>\n

\u6750\u6599<\/span><\/strong><\/strong><\/h3>\n


<\/span><\/strong><\/strong><\/p>\n

<\/p>\n

\u5178\u578b\u7684\u4eba\u5de5\u7ec6\u80de\u819c\u3002<\/span><\/p>\n


<\/span><\/p>\n

\u7528\u4e8e\u4eba\u5de5\u7ec6\u80de\u7684\u819c\u53ef\u4ee5\u7531\u7b80\u5355\u7684\u805a\u5408\u7269\u3001\u4ea4\u8054\u86cb\u767d\u8d28\u3001\u8102\u8d28\u819c\u6216\u805a\u5408\u7269-\u8102\u8d28\u590d\u5408\u7269\u5236\u6210\u3002\u6b64\u5916\uff0c\u819c\u53ef\u4ee5\u88ab\u8bbe\u8ba1\u6210\u8868\u9762\u86cb\u767d\u5982\u767d\u86cb\u767d\u3001\u6297\u539f\u3001 Na\/K-ATP \u9176\u8f7d\u4f53\u6216\u5b54\u9699\u5982\u79bb\u5b50\u901a\u9053\u3002\u5e38\u7528\u7684\u6c34\u51dd\u80f6\u805a\u5408\u7269\u5982\u6d77\u85fb\u9178\u94a0\u3001\u7ea4\u7ef4\u7d20\u548c\u70ed\u5851\u6027\u805a\u5408\u7269\u5982\u7532\u57fa\u4e19\u70ef\u9178\u7f9f\u4e59\u916f-\u7532\u57fa\u4e19\u70ef\u9178\u7532\u916f(HEMA-MMA)\u3001\u805a\u4e19\u70ef\u8148-\u805a\u6c2f\u4e59\u70ef(PAN-PVC) \uff0c\u4ee5\u53ca\u4e0a\u8ff0\u5404\u79cd\u805a\u5408\u7269\u7684\u53d8\u5f02\u3002\u6240\u7528\u7684\u6750\u6599\u51b3\u5b9a\u4e86\u7ec6\u80de\u819c\u7684\u6e17\u900f\u6027\uff0c\u5bf9\u4e8e\u805a\u5408\u7269\u6765\u8bf4\uff0c\u8fd9\u53d6\u51b3\u4e8e\u622a\u7559\u5206\u5b50\u91cf(MWCO)\u3002MWCO \u662f\u53ef\u4ee5\u81ea\u7531\u901a\u8fc7\u5b54\u9699\u7684\u5206\u5b50\u7684\u6700\u5927\u5206\u5b50\u91cf\uff0c\u5bf9\u4e8e\u786e\u5b9a\u8425\u517b\u7269\u8d28\u3001\u5e9f\u7269\u548c\u5176\u4ed6\u4e34\u754c\u5206\u5b50\u7684\u5145\u5206\u6269\u6563\u5f88\u91cd\u8981\u3002\u4eb2\u6c34\u6027\u805a\u5408\u7269\u5177\u6709\u751f\u7269\u76f8\u5bb9\u6027\u7684\u6f5c\u529b\uff0c\u53ef\u4ee5\u5236\u6210\u591a\u79cd\u5f62\u5f0f\uff0c\u5305\u62ec\u805a\u5408\u7269\u80f6\u675f\u3001\u6eb6\u80f6-\u51dd\u80f6\u6df7\u5408\u7269\u3001\u7269\u7406\u5171\u6df7\u7269\u4ee5\u53ca\u4ea4\u8054\u7c92\u5b50\u548c\u7eb3\u7c73\u7c92\u5b50\u3002\u7279\u522b\u4ee4\u4eba\u611f\u5174\u8da3\u7684\u662f\u5bf9pH\u503c\u6216\u6e29\u5ea6\u53d8\u5316\u6709\u53cd\u5e94\u7684\u523a\u6fc0\u6027\u805a\u5408\u7269\uff0c\u7528\u4e8e\u9776\u5411\u4f20\u9012\u3002\u7531\u4e8e pH \u503c\u548c\u6e29\u5ea6\u7684\u4e0d\u540c\uff0c\u8fd9\u4e9b\u805a\u5408\u7269\u53ef\u4ee5\u901a\u8fc7\u5b8f\u89c2\u6ce8\u5c04\u548c\u51dd\u56fa\u6216\u539f\u4f4d\u51dd\u80f6\u4ee5\u6db2\u4f53\u5f62\u5f0f\u7ed9\u836f\u3002\u7eb3\u7c73\u9897\u7c92\u548c\u8102\u8d28\u4f53\u5236\u5242\u4e5f\u5e38\u7528\u4e8e\u6750\u6599\u7684\u5305\u5c01\u548c\u9012\u9001\u3002\u8102\u8d28\u4f53\u7684\u4e00\u4e2a\u4e3b\u8981\u4f18\u70b9\u662f\u5b83\u4eec\u80fd\u591f\u4e0e\u7ec6\u80de\u819c\u548c\u7ec6\u80de\u5668\u819c\u878d\u5408\u3002<\/span><\/p>\n


<\/p>\n

\u5236\u5907<\/span><\/strong><\/strong><\/h3>\n

\u4eba\u5de5\u7ec6\u80de\u7684\u5236\u5907\u548c\u5305\u5c01\u5df2\u7ecf\u53d1\u5c55\u51fa\u8bb8\u591a\u4e0d\u540c\u7684\u65b9\u6cd5\u3002\u901a\u5e38\uff0c\u5982\u7eb3\u7c73\u7c92\u5b50\u3001\u805a\u5408\u7269\u6216\u8102\u8d28\u4f53\u7b49\u5c0f\u6ce1\u88ab\u5408\u6210\u3002\u4e73\u5316\u6db2\u901a\u5e38\u662f\u901a\u8fc7\u9ad8\u538b\u8bbe\u5907\uff0c\u5982\u9ad8\u538b\u5300\u6d46\u5668\u6216\u5fae\u5c04\u6d41\u673a\u6765\u5236\u9020\u7684\u3002\u4e0b\u9762\u5c06\u4ecb\u7ecd\u785d\u5316\u7ea4\u7ef4\u7d20\u7684\u4e24\u79cd\u5fae\u80f6\u56ca\u5316\u65b9\u6cd5.<\/span><\/p>\n


<\/span><\/p>\n

\u9ad8\u538b\u5747\u8d28\u5316 High-pressure homogenization<\/span><\/strong><\/span><\/h4>\n

\u5728\u9ad8\u538b\u5300\u6d46\u5668\u4e2d\uff0c\u6cb9\/\u6db2\u60ac\u6d6e\u6db2\u4e2d\u7684\u4e24\u79cd\u6db2\u4f53\u5728\u5f88\u9ad8\u7684\u538b\u529b\u4e0b\u901a\u8fc7\u4e00\u4e2a\u5c0f\u5b54\u3002\u8fd9\u4e00\u8fc7\u7a0b\u5212\u5206\u4e86\u4ea7\u54c1\uff0c\u5e76\u5141\u8bb8\u4ea7\u751f\u6781\u7ec6\u7684\u9897\u7c92\uff0c\u5c0f\u52301nm\u3002<\/span><\/p>\n


<\/p>\n

\u5fae\u5c04\u6d41\u5904\u7406 Microfluidization<\/span><\/strong><\/span><\/h4>\n

\u5fae\u5c04\u6d41\u6280\u672f\u4f7f\u7528\u4e13\u5229\u7684\u5fae\u5c04\u6d41\u673a\u83b7\u5f97\u66f4\u591a\u7684\u5747\u8d28\u60ac\u6d6e\u6db2\uff0c\u53ef\u4ee5\u4ea7\u751f\u6bd4\u5300\u6d46\u5668\u66f4\u5c0f\u7684\u9897\u7c92\u3002\u5300\u6d46\u5668\u9996\u5148\u88ab\u7528\u6765\u5236\u9020\u7c97\u9897\u7c92\u60ac\u6d6e\u6db2\uff0c\u7136\u540e\u5728\u9ad8\u538b\u4e0b\u88ab\u6cf5\u5165\u5fae\u5c04\u6d41\u673a\u3002\u7136\u540e\u5c06\u6d41\u4f53\u5206\u6210\u4e24\u80a1\u6d41\u4f53\uff0c\u8fd9\u4e24\u80a1\u6d41\u4f53\u5c06\u5728\u76f8\u4e92\u4f5c\u7528\u5ba4\u4e2d\u4ee5\u975e\u5e38\u9ad8\u7684\u901f\u5ea6\u53cd\u5e94\uff0c\u76f4\u5230\u5f97\u5230\u6240\u9700\u7684\u7c92\u5b50\u5c3a\u5bf8\u3002\u8fd9\u79cd\u6280\u672f\u5141\u8bb8\u5927\u89c4\u6a21\u751f\u4ea7\u78f7\u8102\u8102\u8d28\u4f53\u548c\u540e\u7eed\u6750\u6599\u7eb3\u7c73\u5305\u57cb\u3002<\/span><\/p>\n


<\/p>\n

\u70b9\u6ef4\u6cd5 Drop method<\/span><\/strong><\/span><\/h4>\n

\u5728\u8fd9\u79cd\u65b9\u6cd5\u4e2d\uff0c\u7ec6\u80de\u6eb6\u6db2\u6ef4\u5165\u785d\u9178\u7ea4\u7ef4\u7d20\u7684\u706b\u68c9\u80f6\u6eb6\u6db2\u4e2d\u3002\u5f53\u6db2\u6ef4\u901a\u8fc7\u706b\u68c9\u80f6\u65f6\uff0c\u7531\u4e8e\u706b\u68c9\u80f6\u7684\u754c\u9762\u805a\u5408\u7279\u6027\uff0c\u5b83\u88ab\u6d82\u4e0a\u4e86\u4e00\u5c42\u819c\u3002\u7ec6\u80de\u968f\u540e\u6c89\u79ef\u5728\u77f3\u8721\u4e2d\uff0c\u7ec6\u80de\u819c\u51dd\u56fa\uff0c\u6700\u540e\u60ac\u6d6e\u5728\u76d0\u6eb6\u6db2\u4e2d\u3002\u70b9\u6ef4\u6cd5\u7528\u4e8e\u5236\u9020\u5927\u578b\u4eba\u5de5\u7ec6\u80de\uff0c\u5305\u88f9\u751f\u7269\u7ec6\u80de\u3001\u5e72\u7ec6\u80de\u548c\u57fa\u56e0\u5de5\u7a0b\u5e72\u7ec6\u80de\u3002<\/span><\/p>\n


<\/p>\n

\u4e73\u5316\u6cd5 Emulsion method<\/span><\/strong><\/span><\/h4>\n

\u4e73\u5316\u6cd5\u7684\u4e0d\u540c\u4e4b\u5904\u5728\u4e8e\uff0c\u8981\u88ab\u5305\u88f9\u7684\u6750\u6599\u901a\u5e38\u8f83\u5c0f\uff0c\u88ab\u653e\u7f6e\u5728\u53cd\u5e94\u5ba4\u7684\u5e95\u90e8\uff0c\u5728\u53cd\u5e94\u5ba4\u7684\u9876\u90e8\u52a0\u5165\u706b\u68c9\u80f6\u5e76\u79bb\u5fc3\uff0c\u6216\u4ee5\u5176\u4ed6\u65b9\u5f0f\u6405\u62cc\u4ee5\u4fbf\u5f62\u6210\u4e73\u5316\u6db2\u3002\u7136\u540e\u5c06\u80f6\u56ca\u6750\u6599\u5206\u6563\u5e76\u60ac\u6d6e\u5728\u76d0\u6eb6\u6db2\u4e2d\u3002<\/span><\/p>\n


<\/p>\n

\u6750\u6599<\/span><\/strong><\/strong><\/h3>\n

\u836f\u7269\u7684\u91ca\u653e\u548c\u8fd0\u9001<\/span><\/strong><\/span><\/h4>\n

\u7528\u4e8e\u836f\u7269\u8fd0\u9001\u7684\u4eba\u5de5\u7ec6\u80de\u4e0e\u5176\u4ed6\u4eba\u5de5\u7ec6\u80de\u4e0d\u540c\uff0c\u662f\u7531\u4e8e\u5176\u5185\u5bb9\u7269\u8981\u6269\u6563\u51fa\u7ec6\u80de\u819c\uff0c\u6216\u8005\u88ab\u5bbf\u4e3b\u9776\u7ec6\u80de\u541e\u566c\u548c\u6d88\u5316\u3002\u901a\u5e38\u4f7f\u7528\u7684\u662f\u4e9a\u5fae\u7c73\uff0c\u8102\u8d28\u819c\u4eba\u5de5\u7ec6\u80de\uff0c\u53ef\u79f0\u4e3a\u7eb3\u7c73\u80f6\u56ca\uff0c\u7eb3\u7c73\u7c92\u5b50\uff0c\u805a\u5408\u4f53\uff0c\u6216\u5176\u4ed6\u53d8\u4f53\u3002<\/span><\/p>\n


<\/p>\n

\u9176\u7597\u6cd5 Enzyme therapy<\/span><\/strong><\/span><\/h4>\n

\u76ee\u524d\u6b63\u5728\u79ef\u6781\u7814\u7a76\u9176\u7597\u6cd5\uff0c\u7528\u4e8e\u6cbb\u7597\u6709\u67d0\u79cd\u9176\u8fc7\u5ea6\u8868\u8fbe\u3001\u8868\u8fbe\u4e0d\u8db3\u3001\u6709\u7f3a\u9677\u6216\u6839\u672c\u4e0d\u5b58\u5728\u7b49\u8868\u73b0\u7684\u9057\u4f20\u4ee3\u8c22\u6027\u75be\u75c5\u3002\u5728\u6709\u7f3a\u9677\u7684\u9176\u7684\u8868\u8fbe\u4e0d\u8db3\u6216\u8868\u8fbe\u4e0d\u8db3\u7684\u60c5\u51b5\u4e0b\uff0c\u6d3b\u6027\u5f62\u5f0f\u7684\u8be5\u79cd\u9176\u5c06\u88ab\u5f15\u5165\u4eba\u4f53\u4ee5\u5f25\u8865\u7f3a\u9677\u3002\u53e6\u4e00\u65b9\u9762\uff0c\u9176\u7684\u8fc7\u5ea6\u8868\u8fbe\u53ef\u4ee5\u901a\u8fc7\u5f15\u5165\u7ade\u4e89\u6027\u7684\u975e\u529f\u80fd\u6027\u9176\u6765\u62b5\u6d88\uff0c\u4e5f\u5c31\u662f\u8bf4\uff0c\u4e00\u79cd\u5c06\u5e95\u7269\u4ee3\u8c22\u4e3a\u975e\u6d3b\u6027\u4ea7\u7269\u7684\u9176\u3002\u5f53\u7f6e\u4e8e\u4eba\u5de5\u7ec6\u80de\u4e2d\u65f6\uff0c\u9176\u53ef\u4ee5\u6bd4\u6e38\u79bb\u9176\u66f4\u957f\u65f6\u95f4\u5730\u53d1\u6325\u4f5c\u7528\uff0c\u5e76\u4e14\u53ef\u4ee5\u901a\u8fc7\u805a\u5408\u7269\u63a5\u5408\u8fdb\u4e00\u6b65\u4f18\u5316\u3002<\/span><\/p>\n


\u4eba\u5de5\u7ec6\u80de\u5305\u88f9\u6cd5\u7814\u7a76\u7684\u7b2c\u4e00\u79cd\u9176\u662f\u6cbb\u7597\u5c0f\u9f20\u6dcb\u5df4\u8089\u7624\u7684\u5929\u51ac\u9170\u80fa\u9176\u3002\u8fd9\u79cd\u6cbb\u7597\u5ef6\u7f13\u4e86\u80bf\u7624\u7684\u53d1\u751f\u548c\u751f\u957f\u3002\u8fd9\u4e9b\u521d\u6b65\u7684\u53d1\u73b0\u5bfc\u81f4\u4e86\u5728\u916a\u6c28\u9178\u4f9d\u8d56\u6027\u9ed1\u8272\u7d20\u7624\u4e2d\u4f7f\u7528\u4eba\u5de5\u7ec6\u80de\u8fdb\u884c\u9176\u4f20\u9012\u7684\u8fdb\u4e00\u6b65\u7814\u7a76\u3002\u8fd9\u4e9b\u80bf\u7624\u7684\u751f\u957f\u6bd4\u6b63\u5e38\u7ec6\u80de\u66f4\u4f9d\u8d56\u4e8e\u916a\u6c28\u9178\uff0c\u7814\u7a76\u8868\u660e\uff0c\u964d\u4f4e\u5c0f\u9f20\u5168\u8eab\u916a\u6c28\u9178\u6c34\u5e73\u53ef\u4ee5\u6291\u5236\u9ed1\u8272\u7d20\u7624\u7684\u751f\u957f\u3002\u5229\u7528\u4eba\u5de5\u7ec6\u80de\u8f93\u9001\u916a\u6c28\u9178\u9176\u548c\u6d88\u5316\u916a\u6c28\u9178\u7684\u9176\uff0c\u53ef\u4ee5\u63d0\u9ad8\u9176\u7684\u7a33\u5b9a\u6027\uff0c\u5e76\u4e14\u80fd\u6709\u6548\u5730\u53bb\u9664\u916a\u6c28\u9178\uff0c\u800c\u4e0d\u4f1a\u4ea7\u751f\u4e0e\u996e\u98df\u4e2d\u916a\u6c28\u9178\u6076\u5316\u6709\u5173\u7684\u4e25\u91cd\u526f\u4f5c\u7528\u3002<\/span><\/p>\n


\u5728\u67d0\u4e9b\u764c\u75c7\u4e2d\uff0c\u4eba\u5de5\u7ec6\u80de\u9176\u7597\u6cd5\u5bf9\u4e8e\u6fc0\u6d3b\u8bf8\u5982\u5f02\u73af\u78f7\u9170\u80fa\u4e4b\u7c7b\u7684\u524d\u836f\u4e5f\u5f88\u6709\u610f\u4e49\u3002\u5c06\u7ec6\u80de\u8272\u7d20 p450\u9176\u5305\u88f9\u5728\u4eba\u5de5\u7ec6\u80de\u4e2d\uff0c\u5c06\u5176\u8f6c\u5316\u4e3a\u6d3b\u6027\u836f\u7269\uff0c\u53ef\u4ee5\u7279\u5236\u5730\u5728\u80f0\u817a\u764c\u4e2d\u79ef\u7d2f\uff0c\u6216\u5c06\u4eba\u5de5\u7ec6\u80de\u79fb\u690d\u5230\u80bf\u7624\u90e8\u4f4d\u9644\u8fd1\u3002\u5728\u8fd9\u91cc\uff0c\u88ab\u6fc0\u6d3b\u7684\u5f02\u73af\u78f7\u9170\u80fa\u7684\u5c40\u90e8\u6d53\u5ea6\u5c06\u8fdc\u8fdc\u9ad8\u4e8e\u8eab\u4f53\u5176\u4ed6\u90e8\u4f4d\uff0c\u4ece\u800c\u9632\u6b62\u5168\u8eab\u4e2d\u6bd2\u3002\u8fd9\u79cd\u6cbb\u7597\u5728\u52a8\u7269\u8eab\u4e0a\u53d6\u5f97\u4e86\u6210\u529f\uff0c\u5728 I\/II \u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u665a\u671f\u80f0\u817a\u764c\u60a3\u8005\u7684\u751f\u5b58\u7387\u4e2d\u4f4d\u6570\u589e\u52a0\u4e86\u4e00\u500d\uff0c\u4e00\u5e74\u751f\u5b58\u7387\u589e\u52a0\u4e86\u4e24\u500d\u3002<\/span><\/p>\n


<\/p>\n

\u57fa\u56e0\u7597\u6cd5 Gene therapy<\/span><\/strong><\/span><\/h4>\n

\u5728\u57fa\u56e0\u75be\u75c5\u7684\u6cbb\u7597\u4e2d\uff0c\u57fa\u56e0\u7597\u6cd5\u65e8\u5728\u63d2\u5165\u3001\u6539\u53d8\u6216\u79fb\u9664\u53d7\u5f71\u54cd\u4e2a\u4f53\u7ec6\u80de\u5185\u7684\u57fa\u56e0\u3002\u8be5\u6280\u672f\u4e25\u91cd\u4f9d\u8d56\u4e8e\u75c5\u6bd2\u8f7d\u4f53\uff0c\u8fd9\u5f15\u8d77\u4e86\u5bf9\u63d2\u5165\u7a81\u53d8\u548c\u7cfb\u7edf\u514d\u75ab\u53cd\u5e94\u7684\u5173\u6ce8\uff0c\u5b83\u4eec\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u5bfc\u81f4\u4e86\u4eba\u7c7b\u6b7b\u4ea1\u548c\u767d\u8840\u75c5\u7684\u53d1\u5c55\u3002\u5229\u7528\u88f8DNA\u6216\u8d28\u7c92DNA\u4f5c\u4e3a\u8f7d\u4f53\u8f7d\u4f53\u672c\u8eab\u7684\u4f20\u9012\u7cfb\u7edf\uff0c\u907f\u514d\u4e86\u8f7d\u4f53\u7684\u9700\u8981\uff0c\u540c\u65f6\u4e5f\u9047\u5230\u4e86\u7cfb\u7edf\u4f20\u9012\u6548\u7387\u4f4e\u3001\u7ec4\u7ec7\u9776\u5411\u6027\u5dee\u7b49\u95ee\u9898\u3002<\/span><\/p>\n


\u4eba\u5de5\u7ec6\u80de\u88ab\u8ba4\u4e3a\u662f\u4e00\u79cd\u975e\u75c5\u6bd2\u8f7d\u4f53\uff0c\u5c06\u8f6c\u57fa\u56e0\u975e\u81ea\u4f53\u7ec6\u80de\u5305\u88f9\u8d77\u6765\u5e76\u690d\u5165\u4f53\u5185\u4ee5\u8868\u8fbe\u91cd\u7ec4\u86cb\u767d\u3002\u901a\u8fc7\u4f20\u9012\u542b\u6709\u5c0f\u9f20\u751f\u957f\u6fc0\u7d20\u7684\u4eba\u5de5\u7ec6\u80de\uff0c\u633d\u6551\u4e86\u7a81\u53d8\u5c0f\u9f20\u7684\u751f\u957f\u8fdf\u7f13\uff0c\u8fd9\u79cd\u514d\u75ab\u5206\u79bb\u5df2\u7ecf\u88ab\u8bc1\u660e\u662f\u6709\u6548\u7684\u3002\u4e00\u4e9b\u6cbb\u7597\u80f0\u817a\u764c\u3001\u810a\u9ad3\u4fa7\u7d22\u786c\u5316\u75c7\u548c\u75bc\u75db\u63a7\u5236\u7684\u65b9\u6848\u5df2\u7ecf\u8fdb\u5165\u4eba\u4f53\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u3002<\/span><\/p>\n


<\/p>\n

\u8840\u6db2\u704c\u6d41 Hemoperfusion<\/span><\/strong><\/span><\/h4>\n

\u4e34\u5e8a\u4e0a\u7b2c\u4e00\u6b21\u4f7f\u7528\u4eba\u5de5\u7ec6\u80de\u7684\u65b9\u6cd5\u662f\u7528\u6d3b\u6027\u70ad\u5305\u88f9\u8840\u6db2\u704c\u6d41\u3002\u836f\u7528\u6d3b\u6027\u70ad\u5177\u6709\u5438\u9644\u8bb8\u591a\u5927\u5206\u5b50\u7684\u80fd\u529b\uff0c\u957f\u671f\u4ee5\u6765\u56e0\u5176\u5728\u610f\u5916\u4e2d\u6bd2\u6216\u8fc7\u91cf\u670d\u7528\u4e2d\u80fd\u591f\u53bb\u9664\u8840\u6db2\u4e2d\u7684\u6709\u6bd2\u7269\u8d28\u800c\u95fb\u540d\u3002\u7136\u800c\uff0c\u901a\u8fc7\u76f4\u63a5\u4f7f\u7528\u6728\u70ad\u8fdb\u884c\u704c\u6ce8\u662f\u6709\u6bd2\u7684\uff0c\u56e0\u4e3a\u5b83\u4f1a\u5bfc\u81f4\u8840\u6813\u548c\u8840\u7ec6\u80de\u635f\u4f24\uff0c\u968f\u540e\u88ab\u8840\u5c0f\u677f\u6e05\u9664\u3002\u4eba\u5de5\u7ec6\u80de\u5141\u8bb8\u6bd2\u7d20\u6269\u6563\u5230\u7ec6\u80de\u4e2d\uff0c\u540c\u65f6\u5c06\u5371\u9669\u7269\u8d28\u4fdd\u5b58\u5728\u8d85\u8584\u7684\u819c\u5185\u3002<\/span><\/p>\n


\u4e0e\u8840\u6db2\u900f\u6790\u76f8\u6bd4\uff0c\u4eba\u5de5\u7ec6\u80de\u8840\u6db2\u704c\u6d41\u88ab\u8ba4\u4e3a\u662f\u4e00\u79cd\u6210\u672c\u66f4\u4f4e\u3001\u6548\u7387\u66f4\u9ad8\u7684\u89e3\u6bd2\u65b9\u6cd5\u3002\u5728\u8840\u6db2\u704c\u6d41\u4e2d\uff0c\u6210\u5343\u4e0a\u4e07\u7684\u5438\u9644\u6027\u4eba\u5de5\u7ec6\u80de\u901a\u8fc7\u5728\u75c5\u4eba\u8840\u6db2\u704c\u6d41\u7684\u4e24\u7aef\u4f7f\u7528\u4e24\u4e2a\u7b5b\u5b50\u88ab\u4fdd\u5b58\u5728\u4e00\u4e2a\u5c0f\u5bb9\u5668\u5185\u3002\u968f\u7740\u8840\u6db2\u5faa\u73af\uff0c\u6bd2\u7d20\u6216\u836f\u7269\u6269\u6563\u8fdb\u5165\u7ec6\u80de\uff0c\u5e76\u88ab\u5438\u6536\u6750\u6599\u6240\u4fdd\u7559\u3002\u4eba\u5de5\u7ec6\u80de\u7684\u7ec6\u80de\u819c\u6bd4\u900f\u6790\u7528\u7ec6\u80de\u7684\u7ec6\u80de\u819c\u8981\u8584\u5f97\u591a\uff0c\u7ec6\u80de\u819c\u7684\u5c0f\u4f53\u79ef\u610f\u5473\u7740\u7ec6\u80de\u819c\u7684\u8868\u9762\u79ef\u5f88\u5927\u3002\u8fd9\u610f\u5473\u7740\u4e00\u90e8\u5206\u7ec6\u80de\u7406\u8bba\u4e0a\u7684\u8d28\u91cf\u4f20\u9012\u6bd4\u6574\u4e2a\u4eba\u5de5\u80be\u810f\u673a\u5668\u7684\u8d28\u91cf\u4f20\u9012\u9ad8\u767e\u500d\u3002\u8be5\u88c5\u7f6e\u5df2\u88ab\u786e\u7acb\u4e3a\u6cbb\u7597\u610f\u5916\u6216\u81ea\u6740\u6027\u4e2d\u6bd2\u60a3\u8005\u7684\u5e38\u89c4\u4e34\u5e8a\u65b9\u6cd5\uff0c\u4f46\u4e5f\u88ab\u5f15\u5165\u6cbb\u7597\u809d\u529f\u80fd\u8870\u7aed\u548c\u80be\u529f\u80fd\u8870\u7aed\uff0c\u4ee5\u5b9e\u73b0\u8fd9\u4e9b\u5668\u5b98\u7684\u90e8\u5206\u529f\u80fd\u3002\u4eba\u5de5\u7ec6\u80de\u8840\u6db2\u704c\u6d41\u4e5f\u88ab\u63d0\u8bae\u7528\u4e8e\u514d\u75ab\u5438\u9644\uff0c\u901a\u8fc7\u5728\u4eba\u5de5\u7ec6\u80de\u8868\u9762\u7c98\u9644\u514d\u75ab\u5438\u9644\u6750\u6599\uff0c\u5982\u767d\u86cb\u767d\uff0c\u53ef\u5c06\u6297\u4f53\u4ece\u4f53\u5185\u9664\u53bb\u3002\u8fd9\u4e00\u539f\u7406\u5df2\u88ab\u5e94\u7528\u4e8e\u4ece\u9aa8\u9ad3\u79fb\u690d\u60a3\u8005\u8840\u6d46\u4e2d\u53bb\u9664\u8840\u578b\u6297\u4f53\uff0c\u4ee5\u53ca\u901a\u8fc7\u5355\u514b\u9686\u6297\u4f53\u53bb\u9664\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u6cbb\u7597\u9ad8\u80c6\u56fa\u9187\u8840\u75c7\u3002\u8840\u6db2\u704c\u6d41\u5728\u8840\u6db2\u900f\u6790\u5236\u9020\u4e1a\u8584\u5f31\u7684\u56fd\u5bb6\u5c24\u5176\u6709\u7528\uff0c\u56e0\u4e3a\u90a3\u91cc\u7684\u8840\u6db2\u900f\u6790\u8bbe\u5907\u5f80\u5f80\u66f4\u4fbf\u5b9c\uff0c\u800c\u4e14\u7528\u4e8e\u80be\u8870\u7aed\u60a3\u8005\u3002<\/span><\/p>\n


<\/p>\n

\u5fae\u56ca\u7ec6\u80de<\/span><\/strong><\/span><\/h4>\n


<\/span><\/strong><\/p>\n

<\/p>\n

\u4eba\u5de5\u819c\u5185\u5fae\u56ca\u7ec6\u80de\u7684\u539f\u7406\u56fe\u8868\u793a\u3002<\/span><\/p>\n


\u6700\u5e38\u7528\u7684\u5236\u5907\u4eba\u5de5\u7ec6\u80de\u7684\u65b9\u6cd5\u662f\u7ec6\u80de\u5305\u88f9\u3002\u5fae\u56ca\u7ec6\u80de\u901a\u5e38\u7531\u6db2\u4f53\u7ec6\u80de\u60ac\u6d6e\u6db2\u4e2d\u4ea7\u751f\u63a7\u5236\u5c3a\u5bf8\u7684\u6db2\u6ef4\u83b7\u53d6\uff0c\u7136\u540e\u5feb\u901f\u51dd\u56fa\u6216\u51dd\u80f6\u5316\u4ee5\u63d0\u4f9b\u989d\u5916\u7684\u7a33\u5b9a\u6027\u3002\u7a33\u5b9a\u5316\u53ef\u4ee5\u901a\u8fc7\u6e29\u5ea6\u7684\u53d8\u5316\u6216\u6750\u6599\u7684\u4ea4\u8054\u6765\u5b9e\u73b0\u3002\u7ec6\u80de\u7684\u5fae\u73af\u5883\u5728\u5305\u88f9\u540e\u53d1\u751f\u53d8\u5316\uff0c\u4e14\u901a\u5e38\u4ece\u5355\u5206\u5b50\u5c42\u5230\u60ac\u6d6e\u5728\u805a\u5408\u7269\u819c\u5185\u7684\u805a\u5408\u7269\u652f\u67b6\u4e0a\u3002\u8fd9\u79cd\u6280\u672f\u7684\u7f3a\u70b9\u662f\u5fae\u56ca\u7ec6\u80de\u4f1a\u964d\u4f4e\u5176\u751f\u5b58\u80fd\u529b\u4ee5\u53ca\u589e\u6b96\u548c\u5206\u5316\u80fd\u529b\u3002\u6b64\u5916\uff0c\u5728\u5fae\u56ca\u4e2d\u5f85\u4e00\u6bb5\u65f6\u95f4\u540e\uff0c\u7ec6\u80de\u4f1a\u5f62\u6210\u56e2\u7c07\uff0c\u6291\u5236\u6c27\u6c14\u548c\u4ee3\u8c22\u5e9f\u7269\u7684\u4ea4\u6362\uff0c\u5bfc\u81f4\u7ec6\u80de\u51cb\u4ea1\u548c\u574f\u6b7b\uff0c\u4ece\u800c\u9650\u5236\u7ec6\u80de\u7684\u529f\u6548\uff0c\u6fc0\u6d3b\u5bbf\u4e3b\u7684\u514d\u75ab\u7cfb\u7edf\u3002\u4eba\u5de5\u7ec6\u80de\u5df2\u7ecf\u6210\u529f\u5730\u79fb\u690d\u4e86\u4e00\u4e9b\u7ec6\u80de\uff0c\u5305\u62ec\u6cbb\u7597\u7cd6\u5c3f\u75c5\u7684\u80f0\u5c9b\u3001\u7532\u72b6\u65c1\u817a\u7ec6\u80de\u548c\u80be\u4e0a\u817a\u76ae\u8d28\u7ec6\u80de\u3002<\/span><\/p>\n


<\/p>\n

\u5fae\u56ca\u809d\u7ec6\u80de Encapsulated hepatocytes<\/span><\/strong><\/span><\/h4>\n

\u5668\u5b98\u6350\u732e\u8005\u7684\u77ed\u7f3a\u4f7f\u4eba\u5de5\u7ec6\u80de\u6210\u4e3a\u6cbb\u7597\u809d\u8870\u7aed\u66ff\u4ee3\u7597\u6cd5\u7684\u5173\u952e\u3002\u4eba\u5de5\u7ec6\u80de\u7528\u4e8e\u809d\u7ec6\u80de\u79fb\u690d\u5df2\u88ab\u8bc1\u5b9e\u5728\u52a8\u7269\u809d\u75c5\u6a21\u578b\u548c\u751f\u7269\u4eba\u5de5\u809d\u88c5\u7f6e\u4e2d\u63d0\u4f9b\u809d\u529f\u80fd\u7684\u53ef\u884c\u6027\u548c\u6709\u6548\u6027\u3002\u5b9e\u9a8c\u4e2d\uff0c\u809d\u7ec6\u80de\u9644\u7740\u5728\u5fae\u8f7d\u4f53\u8868\u9762\uff0c\u7136\u540e\u8fdb\u5316\u6210\u5305\u88f9\u5728\u7531\u805a\u8d56\u6c28\u9178\u5916\u76ae\u8986\u76d6\u7684\u6d77\u85fb\u9178\u94a0\u5fae\u6ef4\u4e2d\u7684\u4e09\u7ef4\u57fa\u8d28\u4e2d\u7684\u809d\u7ec6\u80de\u3002\u8fd9\u79cd\u7ed9\u836f\u65b9\u6cd5\u7684\u4e00\u4e2a\u5173\u952e\u4f18\u52bf\u662f\u5728\u6cbb\u7597\u671f\u95f4\u907f\u514d\u4e86\u514d\u75ab\u6291\u5236\u6cbb\u7597\u3002\u5fae\u56ca\u809d\u7ec6\u80de\u5df2\u88ab\u63d0\u8bae\u7528\u4e8e\u751f\u7269\u4eba\u5de5\u809d\u3002\u8be5\u88c5\u7f6e\u7531\u4e00\u4e2a\u5d4c\u6709\u5206\u79bb\u809d\u7ec6\u80de\u7684\u5706\u67f1\u5f62\u8154\u5ba4\u7ec4\u6210\uff0c\u75c5\u4eba\u7684\u8840\u6d46\u901a\u8fc7\u8fd9\u4e2a\u8154\u5ba4\u5728\u4e00\u79cd\u8840\u6db2\u704c\u6d41\u4e2d\u5faa\u73af\u3002\u7531\u4e8e\u5fae\u56ca\u5177\u6709\u5f88\u9ad8\u7684\u6bd4\u8868\u9762\u79ef\u548c\u4f53\u79ef\u6bd4\uff0c\u5b83\u4eec\u4e3a\u57fa\u8d28\u6269\u6563\u63d0\u4f9b\u4e86\u8f83\u5927\u7684\u8868\u9762\u79ef\uff0c\u5e76\u4e14\u53ef\u4ee5\u5bb9\u7eb3\u5927\u91cf\u7684\u809d\u7ec6\u80de\u3002\u5bf9\u8bf1\u5bfc\u6027\u809d\u8870\u7aed\u5c0f\u9f20\u7684\u6cbb\u7597\u663e\u793a\u5b58\u6d3b\u7387\u663e\u8457\u63d0\u9ad8\u3002\u4eba\u5de5\u809d\u7cfb\u7edf\u4ecd\u5904\u4e8e\u65e9\u671f\u53d1\u5c55\u9636\u6bb5\uff0c\u4f46\u5bf9\u4e8e\u7b49\u5f85\u5668\u5b98\u79fb\u690d\u6216\u8005\u75c5\u4eba\u81ea\u8eab\u7684\u809d\u810f\u91cd\u65b0\u5145\u5206\u6062\u590d\u6b63\u5e38\u529f\u80fd\u7684\u75c5\u4eba\u6765\u8bf4\uff0c\u663e\u793a\u51fa\u4e86\u6f5c\u529b\u3002\u8fc4\u4eca\u4e3a\u6b62\uff0c\u5e94\u7528\u4eba\u5de5\u809d\u7cfb\u7edf\u548c\u809d\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u7ec8\u672b\u671f\u809d\u75c5\u7684\u4e34\u5e8a\u8bd5\u9a8c\u8868\u660e\uff0c\u5065\u5eb7\u6307\u6807\u6709\u6240\u6539\u5584\uff0c\u4f46\u8fd8\u6ca1\u6709\u63d0\u9ad8\u5b58\u6d3b\u7387\u3002\u79fb\u690d\u540e\u4eba\u5de5\u809d\u7ec6\u80de\u7684\u77ed\u5bff\u547d\u548c\u805a\u96c6\u662f\u76ee\u524d\u809d\u79fb\u690d\u9762\u4e34\u7684\u4e3b\u8981\u969c\u788d\u3002\u4e0e\u5e72\u7ec6\u80de\u4e00\u540c\u5305\u88f9\u7684\u809d\u7ec6\u80de\u5728\u57f9\u517b\u548c\u690d\u5165\u540e\u663e\u793a\u51fa\u66f4\u9ad8\u7684\u5b58\u6d3b\u7387\uff0c\u5355\u72ec\u690d\u5165\u4eba\u5de5\u5e72\u7ec6\u80de\u4e5f\u53ef\u4ee5\u4fc3\u6210\u809d\u7684\u518d\u751f\u3002\u56e0\u6b64\uff0c\u5728\u518d\u751f\u533b\u5b66\u4e2d\u5229\u7528\u5e72\u7ec6\u80de\u5c01\u88c5\u7684\u7814\u7a76\u5f15\u8d77\u4e86\u4eba\u4eec\u7684\u5174\u8da3\u3002<\/span><\/p>\n


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\u5fae\u56ca\u7ec6\u83cc\u7ec6\u80de Encapsulated bacterial cells<\/span><\/strong><\/span><\/h4>\n

\u53e3\u670d\u6d3b\u83cc\u7fa4\uff0c\u76ee\u524d\u6b63\u7528\u4e8e\u6cbb\u7597\u8c03\u8282\u80a0\u9053\u83cc\u7fa4\uff0c\u9884\u9632\u8179\u6cfb\u75be\u75c5\uff0c\u6cbb\u7597\u5e7d\u95e8\u87ba\u6746\u83cc\u611f\u67d3\uff0c\u7279\u5e94\u6027\u708e\u75c7\uff0c\u4e73\u7cd6\u4e0d\u8010\u53d7\u548c\u514d\u75ab\u8c03\u8282\u7b49\u75c7\u75c5\u3002\u867d\u7136\u5176\u4f5c\u7528\u673a\u5236\u5c1a\u672a\u5f97\u5230\u5145\u5206\u7406\u89e3\uff0c\u4f46\u88ab\u8ba4\u4e3a\u5176\u5177\u6709\u4e24\u4e2a\u4e3b\u8981\u4f5c\u7528\u3002\u9996\u5148\u662f\u8425\u517b\u6548\u5e94\uff0c\u5373\u7ec6\u83cc\u4e0e\u4ea7\u6bd2\u7ec6\u83cc\u7ade\u4e89\u3002\u7b2c\u4e8c\u662f\u536b\u751f\u6548\u5e94\uff0c\u5373\u523a\u6fc0\u62b5\u6297\u5b9a\u6b96\u548c\u514d\u75ab\u53cd\u5e94\u3002\u7531\u4e8e\u7ec6\u83cc\u57f9\u517b\u7269\u5f80\u5f80\u662f\u514d\u75ab\u7cfb\u7edf\u7684\u76ee\u6807\uff0c\u901a\u5e38\u4f1a\u5728\u53e3\u670d\u65f6\u88ab\u7834\u574f\uff0c\u53e3\u670d\u7ed9\u836f\u7684\u65b9\u5f0f\u4fbf\u6210\u4e86\u56f0\u96be\u3002\u4eba\u5de5\u7ec6\u80de\u901a\u8fc7\u5411\u4f53\u5185\u63d0\u4f9b\u62df\u6001\uff0c\u4ee5\u53ca\u5176\u53ef\u9009\u62e9\u7684\u6216\u957f\u671f\u7684\u91ca\u653e\uff0c\u6765\u63d0\u9ad8\u8fdb\u5165\u80c3\u80a0\u9053\u7cfb\u7edf\u7684\u7ec6\u83cc\u7684\u751f\u5b58\u80fd\u529b\uff0c\u4ece\u800c\u5e2e\u52a9\u89e3\u51b3\u8fd9\u4e9b\u95ee\u9898\u3002\u6b64\u5916\uff0c\u8fd8\u53ef\u4ee5\u8bbe\u8ba1\u6d3b\u7ec6\u83cc\u5305\u56ca\uff0c\u4f7f\u5c0f\u5206\u5b50(\u5305\u62ec\u591a\u80bd)\u6269\u6563\u5230\u4f53\u5185\uff0c\u4ee5\u7528\u4e8e\u6cbb\u7597\u3002\u918b\u9178\u7ea4\u7ef4\u7d20\u548c\u6d77\u85fb\u9178\u76d0\u7684\u53d8\u4f53\u7b49\u5df2\u88ab\u8bc1\u660e\uff0c\u53ef\u4ee5\u6210\u529f\u7528\u4e8e\u7ec6\u83cc\u4f20\u9012\u7684\u819c\u3002\u5fae\u56ca\u7ec6\u83cc\u7ec6\u80de\u7684\u5176\u4ed6\u7528\u9014\u8fd8\u5305\u62ec\u4fdd\u62a4\u7ec6\u83cc\u7ec6\u80de\u514d\u53d7\u7ed3\u6838\u5206\u679d\u6746\u83cc\u7684\u653b\u51fb\uff0c\u4ee5\u53ca\u4fc3\u8fdb\u514d\u75ab\u7cfb\u7edf\u4ea7\u751fIg\u5206\u6ccc\u7ec6\u80de\u3002\u8be5\u6280\u672f\u53d7\u5230\u7cfb\u7edf\u6027\u611f\u67d3\u3001\u4e0d\u826f\u4ee3\u8c22\u6d3b\u52a8\u548c\u57fa\u56e0\u8f6c\u79fb\u98ce\u9669\u7684\u9650\u5236\u3002\u7136\u800c\uff0c\u66f4\u5927\u7684\u6311\u6218\u4ecd\u7136\u662f\u5982\u4f55\u5c06\u8db3\u591f\u591a\u7684\u6709\u751f\u547d\u7684\u7ec6\u83cc\u8fd0\u9001\u5230\u76ee\u6807\u90e8\u4f4d\u3002<\/span><\/p>\n


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\u4eba\u5de5\u8840\u7ec6\u80de\u4f5c\u4e3a\u6c27\u8f7d\u4f53 Artificial blood cells as oxygen carriers<\/span><\/strong><\/span><\/h4>\n

\u4eba\u5de5\u8840\u7ec6\u80de\u4f5c\u4e3a\u6c27\u8f7d\u4f53\u88ab\u7528\u4f5c\u4e00\u79cd\u7ea2\u7ec6\u80de\u66ff\u4ee3\u54c1\uff0c\u5c3d\u7ba1\u5b83\u4eec\u7f3a\u4e4f\u7ea2\u7ec6\u80de\u7684\u5176\u4ed6\u6210\u5206\u3002\u5b83\u4eec\u7531\u4e00\u79cd\u5408\u6210\u7684\u805a\u5408\u4f53\u6216\u56f4\u7ed5\u7740\u7eaf\u5316\u7684\u52a8\u7269\u3001\u4eba\u6216\u91cd\u7ec4\u7684\u8840\u7ea2\u86cb\u767d\u7684\u4eba\u5de5\u819c\u7ec4\u6210\u3002\u603b\u7684\u6765\u8bf4\uff0c\u8840\u7ea2\u86cb\u767d\u7684\u8f93\u9001\u4ecd\u7136\u662f\u4e00\u4e2a\u6311\u6218\uff0c\u56e0\u4e3a\u5b83\u5728\u6ca1\u6709\u4efb\u4f55\u4fee\u9970\u7684\u60c5\u51b5\u4e0b\u8f93\u9001\u65f6\u662f\u5267\u6bd2\u7684\u3002\u5728\u4e00\u4e9b\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u4eba\u4eec\u89c2\u5bdf\u5230\u8840\u7ba1\u5347\u538b\u6548\u5e94\u3002<\/span><\/p>\n


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\u4eba\u5de5\u7ea2\u7ec6\u80de Artificial red blood cells<\/span><\/strong><\/span><\/h4>\n

\u57281980\u5e74\u4ee3\u7684\u827e\u6ecb\u75c5\u6050\u614c\u4e4b\u540e\uff0c\u4eba\u4eec\u5bf9\u4f7f\u7528\u4eba\u5de5\u7ea2\u7ec6\u80de\u5236\u9020\u8840\u6db2\u4ea7\u751f\u4e86\u7814\u7a76\u5174\u8da3\u3002\u9664\u4e86\u907f\u5f00\u75be\u75c5\u4f20\u64ad\u7684\u53ef\u80fd\u6027\u4e4b\u5916\uff0c\u4eba\u5de5\u7ea2\u7ec6\u80de\u4e5f\u662f\u4eba\u4eec\u6240\u9700\u8981\u7684\uff0c\u56e0\u4e3a\u5b83\u4eec\u53ef\u4ee5\u6d88\u9664\u4e0e\u540c\u79cd\u5f02\u4f53\u8f93\u8840\u76f8\u5173\u7684\u7f3a\u70b9\uff0c\u5982\u8840\u578b\u9274\u5b9a\u3001\u514d\u75ab\u53cd\u5e94\u53ca\u5176\u77ed\u6682\u768442\u5929\u50a8\u5b58\u671f\u3002\u8840\u7ea2\u86cb\u767d\u66ff\u4ee3\u7269\u53ef\u4ee5\u5b58\u653e\u5728\u5ba4\u6e29\u4e0b\uff0c\u800c\u4e0d\u662f\u5728\u51b7\u85cf\u6761\u4ef6\u4e0b\u5b58\u653e\u4e00\u5e74\u4ee5\u4e0a\u3002\u4eba\u4eec\u5df2\u7ecf\u5c1d\u8bd5\u5f00\u53d1\u51fa\u4e00\u79cd\u5b8c\u6574\u5de5\u4f5c\u7684\u7ea2\u7ec6\u80de\uff0c\u5b83\u4e0d\u4ec5\u5305\u542b\u78b3\u9178\uff0c\u800c\u4e14\u5305\u542b\u6c27\u8f7d\u4f53\u548c\u4e0e\u7ec6\u80de\u76f8\u5173\u7684\u9176\u3002\u7b2c\u4e00\u6b21\u5c1d\u8bd5\u662f\u57281957\u5e74\uff0c\u7528\u8d85\u8584\u805a\u5408\u7269\u819c\u4ee3\u66ff\u7ea2\u7ec6\u80de\u819c\uff0c\u7136\u540e\u901a\u8fc7\u8102\u8d28\u819c\u548c\u6700\u8fd1\u7684\u53ef\u751f\u7269\u964d\u89e3\u805a\u5408\u7269\u819c\u8fdb\u884c\u5305\u5c01\u3002\u5305\u62ec\u8102\u7c7b\u548c\u76f8\u5173\u86cb\u767d\u5728\u5185\u7684\u751f\u7269\u7ea2\u7ec6\u80de\u819c\u8fd8\u53ef\u4ee5\u901a\u8fc7\u7ed5\u8fc7\u5de8\u566c\u7ec6\u80de\u6444\u53d6\u548c\u7cfb\u7edf\u6e05\u9664\u6765\u5305\u88f9\u7eb3\u7c73\u9897\u7c92\u548c\u589e\u52a0\u4f53\u5185\u6ede\u7559\u65f6\u95f4\u3002<\/span><\/p>\n


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\u4eba\u5de5\u767d\u7ec6\u80de\u805a\u5408\u4f53 Artificial leuko-polymersomes<\/span><\/strong><\/span><\/h4>\n

\u4eba\u5de5\u767d\u7ec6\u80de\u805a\u5408\u4f53\u662f\u4e00\u79cd\u5177\u6709\u767d\u7ec6\u80de\u7c98\u9644\u7279\u6027\u7684\u9ad8\u5206\u5b50\u56ca\u6ce1\u3002\u9ad8\u5206\u5b50\u56ca\u6ce1\u662f\u7531\u53cc\u5c42\u8584\u7247\u7ec4\u6210\u7684\u56ca\u6ce1\uff0c\u53ef\u4ee5\u5305\u88f9\u8bb8\u591a\u6d3b\u6027\u5206\u5b50\uff0c\u5982\u836f\u7269\u6216\u9176\u3002\u901a\u8fc7\u5c06\u767d\u7ec6\u80de\u7684\u7c98\u9644\u7279\u6027\u6dfb\u52a0\u5230\u7ec6\u80de\u819c\u4e0a\uff0c\u767d\u7ec6\u80de\u53ef\u4ee5\u51cf\u6162\u901f\u5ea6\uff0c\u6216\u8005\u5728\u5feb\u901f\u6d41\u52a8\u7684\u5faa\u73af\u7cfb\u7edf\u5185\u6cbf\u7740\u4e0a\u76ae\u7ec6\u80de\u58c1\u6eda\u52a8\u3002<\/span><\/p>\n


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\u975e\u5e38\u89c4\u7c7b\u578b\u7684\u4eba\u5de5\u7ec6\u80de<\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/p>\n<\/section>\n

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\u7535\u5b50\u4eba\u5de5\u7ec6\u80de Electronic artificial cell<\/span><\/strong><\/span><\/h3>\n

\u7535\u5b50\u4eba\u5de5\u7ec6\u80de\u7684\u6982\u5ff5\u57282004\u5e74\u81f32015\u5e74\u7531\u7ea6\u7ff0 \u00b7 \u9ea6\u5361\u65af\u57fa\u5c14\u534f\u8c03\u7684\u4e00\u7cfb\u5217\u6b27\u76df\u9879\u76ee\u4e2d\u5f97\u5230\u6269\u5c55\u3002<\/span><\/p>\n


2004\u5e74\u81f32008\u5e74\uff0c\u6b27\u6d32\u8054\u76df\u59d4\u5458\u4f1a\u8d5e\u52a9\u5236\u5b9a\u4e86\u53ef\u7f16\u7a0b\u4eba\u5de5\u7ec6\u80de\u8fdb\u5316\u65b9\u6848\uff0c\u5176\u76ee\u6807\u662f\u4e3a\u6700\u7ec8\u878d\u5165\u4fe1\u606f\u7cfb\u7edf\u5960\u5b9a\u57fa\u7840\uff0c\u521b\u5efa\u201d\u7531\u7b80\u5355\u7684\u6709\u673a\u548c\u65e0\u673a\u7269\u8d28\u6784\u6210\u7684\u5fae\u89c2\u81ea\u7ec4\u7ec7\u3001\u81ea\u6211\u590d\u5236\u548c\u53ef\u8fdb\u5316\u7684\u81ea\u4e3b\u5b9e\u4f53\uff0c\u8fd9\u4e9b\u7269\u8d28\u53ef\u901a\u8fc7\u9057\u4f20\u7a0b\u5e8f\u8fdb\u884c\u7f16\u7a0b\uff0c\u4ee5\u5c65\u884c\u7279\u5b9a\u529f\u80fd\u201d\u3002PACE \u9879\u76ee\u5f00\u53d1\u4e86\u7b2c\u4e00\u53f0\u6b27\u7c73\u8304\u673a\u5668\uff0c\u8fd9\u662f\u4e00\u79cd\u4eba\u5de5\u7ec6\u80de\u7684\u5fae\u6d41\u4f53\u751f\u547d\u652f\u6301\u7cfb\u7edf\uff0c\u53ef\u4ee5\u8865\u5145\u5316\u5b66\u7f3a\u5931\u7684\u529f\u80fd(\u6700\u521d\u7531Norman Packard\u3001Steen Rasmussen\u3001Mark Beadau\u548cJohn McCaskill\u57fa\u5c14\u63d0\u51fa)\u3002\u6700\u7ec8\u76ee\u6807\u662f\u5728\u590d\u6742\u7684\u5fae\u578b\u53ef\u7f16\u7a0b\u73af\u5883\u4e2d\u5b9e\u73b0\u53ef\u8fdb\u5316\u7684\u6df7\u5408\u7ec6\u80de\u3002\u6b27\u7c73\u8304\u673a\u5668\u7684\u529f\u80fd\u53ef\u4ee5\u9010\u6b65\u88ab\u79fb\u9664\uff0c\u8fd9\u5bf9\u4eba\u5de5\u7ec6\u80de\u5316\u5b66\u63d0\u51fa\u4e86\u4e00\u7cfb\u5217\u53ef\u89e3\u51b3\u7684\u8fdb\u5316\u6311\u6218\u3002\u8be5\u9879\u76ee\u5b9e\u73b0\u4e86\u4eba\u5de5\u7ec6\u80de\u4e09\u4e2a\u6838\u5fc3\u529f\u80fd(\u9057\u4f20\u5b50\u7cfb\u7edf\u3001\u5305\u5bb9\u7cfb\u7edf\u548c\u65b0\u9648\u4ee3\u8c22\u7cfb\u7edf)\u6210\u5bf9\u7684\u5316\u5b66\u6574\u5408\uff0c\u5e76\u4e3a\u5305\u5bb9\u548c\u57fa\u56e0\u6269\u589e\u7684\u6574\u5408\u521b\u9020\u4e86\u65b0\u7684\u7a7a\u95f4\u5206\u8fa8\u53ef\u7f16\u7a0b\u5fae\u6d41\u4f53\u73af\u5883\u3002\u8fd9\u4e2a\u9879\u76ee\u5bfc\u81f4\u4e86\u6b27\u6d32\u751f\u7269\u6280\u672f\u4e2d\u5fc3\u7684\u5efa\u7acb\u3002<\/span><\/p>\n


\u5728\u8fd9\u9879\u7814\u7a76\u4e4b\u540e\uff0c2007\u5e74\uff0cJohn McCaskill\u57fa\u5c14\u63d0\u8bae\u96c6\u4e2d\u7814\u7a76\u4e00\u79cd\u7535\u5b50\u8865\u5145\u578b\u4eba\u5de5\u7535\u6c60\uff0c\u79f0\u4e3a\u7535\u5b50\u5316\u5b66\u7535\u6c60\u3002\u5173\u952e\u7684\u60f3\u6cd5\u662f\u5728\u4e00\u4e2a\u4e8c\u7ef4\u8584\u819c\u4e2d\uff0c\u4f7f\u7528\u4e00\u4e2a\u5927\u89c4\u6a21\u5e76\u884c\u5904\u7406\u673a\u9635\u5217\u7684\u7535\u6781\u4e0e\u5c40\u90e8\u4e13\u7528\u7535\u5b50\u7535\u8def\u8026\u5408\uff0c\u4ee5\u8865\u5145\u65b0\u51fa\u73b0\u7684\u5316\u5b66\u7ec6\u80de\u529f\u80fd\u3002\u5b9a\u4e49\u7535\u6781\u5207\u6362\u548c\u4f20\u611f\u7535\u8def\u7684\u5c40\u90e8\u7535\u5b50\u4fe1\u606f\u53ef\u4ee5\u4f5c\u4e3a\u7535\u5b50\u57fa\u56e0\u7ec4\uff0c\u8865\u5145\u65b0\u534f\u8bae\u4e2d\u7684\u5206\u5b50\u5e8f\u5217\u4fe1\u606f\u3002\u4e0e\u6b27\u6d32\u8054\u76df\u59d4\u5458\u4f1a\u7684\u4e00\u9879\u7814\u7a76\u63d0\u6848\u53d6\u5f97\u4e86\u6210\u529f\uff0c\u4e0e\u8ba1\u7b97\u673a\u8bbe\u5907\u884c\u52a8\u4f19\u4f34\u5173\u7cfb\u8054\u76df\u90e8\u5206\u91cd\u53e0\u7684\u4e00\u4e2a\u56fd\u9645\u79d1\u5b66\u5bb6\u5c0f\u7ec4\u5f00\u59cb\u4e862008-2012\u5e74\u7535\u5b50\u5316\u5b66\u7ec6\u80de\u9879\u76ee\u7684\u5de5\u4f5c\u3002\u9664\u5176\u4ed6\u5916\uff0c\u8be5\u9879\u76ee\u8868\u660e\uff0c\u7535\u5b50\u63a7\u5236\u7684\u7279\u5b9a\u5e8f\u5217\u7684\u5c40\u90e8\u8f6c\u79fb\u53ef\u4ee5\u7528\u4f5c\u672a\u6765\u4eba\u5de5\u7ec6\u80de\u9057\u4f20\u589e\u6b96\u7684\u4eba\u5de5\u7a7a\u95f4\u63a7\u5236\u7cfb\u7edf\uff0c\u5e76\u4e14\u65b0\u9648\u4ee3\u8c22\u7684\u6838\u5fc3\u8fc7\u7a0b\u53ef\u4ee5\u901a\u8fc7\u9002\u5f53\u7684\u6d82\u5c42\u7535\u6781\u9635\u5217\u4f20\u9012\u3002<\/span><\/p>\n


\u8fd9\u79cd\u65b9\u6cd5\u7684\u4e3b\u8981\u5c40\u9650\u6027\uff0c\u9664\u4e86\u6700\u521d\u5728\u638c\u63e1\u5fae\u89c2\u7535\u5316\u5b66\u548c\u7535\u52a8\u529b\u5b66\u65b9\u9762\u7684\u56f0\u96be\u4e4b\u5916\uff0c\u662f\u628a\u7535\u5b50\u7cfb\u7edf\u4f5c\u4e3a\u4e00\u79cd\u521a\u6027\u7684\u3001\u975e\u81ea\u4e3b\u7684\u5b8f\u89c2\u786c\u4ef6\u8fde\u63a5\u5728\u4e00\u8d77\u30022011\u5e74\uff0c\u9ea6\u5361\u65af\u57fa\u5c14\u63d0\u8bae\u98a0\u5012\u7535\u5b50\u5b66\u548c\u5316\u5b66\u7684\u51e0\u4f55\u5b66: \u4e0d\u628a\u5316\u5b66\u7269\u8d28\u653e\u5728\u6d3b\u8dc3\u7684\u7535\u5b50\u4ecb\u8d28\u4e2d\uff0c\u800c\u662f\u628a\u5fae\u89c2\u7684\u81ea\u4e3b\u7535\u5b50\u5b66\u653e\u5728\u5316\u5b66\u4ecb\u8d28\u4e2d\u3002\u4ed6\u7ec4\u7ec7\u4e86\u4e00\u4e2a\u9879\u76ee\uff0c\u4ee5\u89e3\u51b3\u7b2c\u4e09\u4ee3100\u5fae\u7c73\u89c4\u6a21\u7684\u7535\u5b50\u4eba\u5de5\u7ec6\u80de\u95ee\u9898\uff0c\u8fd9\u79cd\u7ec6\u80de\u53ef\u4ee5\u7531\u4e24\u4e2a\u534a\u7ec6\u80de\u201d\u5b9e\u9a8c\u5ba4\u201d\u81ea\u6211\u7ec4\u88c5\uff0c\u4ee5\u5c01\u95ed\u5185\u90e8\u5316\u5b66\u7a7a\u95f4\uff0c\u5e76\u501f\u52a9\u6d78\u5165\u5176\u4e2d\u7684\u6709\u6e90\u7535\u5b50\u8bbe\u5907\u53d1\u6325\u529f\u80fd\u3002\u8fd9\u4e9b\u7ec6\u80de\u53ef\u4ee5\u590d\u5236\u5b83\u4eec\u7684\u7535\u5b50\u548c\u5316\u5b66\u6210\u5206\uff0c\u5e76\u4e14\u80fd\u591f\u5728\u5b83\u4eec\u7279\u6b8a\u7684\u9884\u5408\u6210\u5fae\u89c2\u6784\u4ef6\u6240\u63d0\u4f9b\u7684\u7ea6\u675f\u6761\u4ef6\u4e0b\u8fdb\u5316\u30022012\u5e749\u6708\uff0c\u8fd9\u4e2a\u9879\u76ee\u5f00\u59cb\u4e86\u5de5\u4f5c\u3002<\/span><\/p>\n


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\u6770\u74e6\u52aa Jeewanu<\/span><\/strong><\/span><\/h3>\n

\u6770\u74e6\u52aa\u539f\u59cb\u7ec6\u80de\u662f\u5177\u6709\u7ec6\u80de\u6837\u7ed3\u6784\u7684\u5408\u6210\u5316\u5b66\u7c92\u5b50\uff0c\u4f3c\u4e4e\u5177\u6709\u4e00\u5b9a\u7684\u529f\u80fd\u6d3b\u6027\u30021963\u5e74\u9996\u6b21\u5728\u9633\u5149\u4e0b\u7531\u7b80\u5355\u77ff\u7269\u8d28\u548c\u57fa\u672c\u6709\u673a\u7269\u5408\u6210\uff0c\u636e\u62a5\u9053\u5b83\u4ecd\u7136\u5177\u6709\u4e00\u4e9b\u65b0\u9648\u4ee3\u8c22\u80fd\u529b\uff0c\u5305\u62ec\u534a\u900f\u819c\u3001\u6c28\u57fa\u9178\u3001\u78f7\u8102\u3001\u78b3\u6c34\u5316\u5408\u7269\u548c\u7c7b RNA\u5206\u5b50\u3002\u7136\u800c\uff0c\u6770\u74e6\u52aa\u7684\u6027\u8d28\u548c\u5c5e\u6027\u4ecd\u6709\u5f85\u6f84\u6e05\u3002<\/span><\/p>\n


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\u4eba\u7c7b\u7ec8\u6781\u6311\u6218\uff1a\u8d4b\u4e88\u4eba\u9020\u7ec6\u80de\u751f\u547d\uff0c\u5168\u4eba\u5de5\u7ec6\u80de\u5b9e\u73b0\u4e34\u8fd1<\/span><\/strong><\/a>
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\u4e8c\u5341\u591a\u5e74\u6765\uff0c\u5236\u9020\u6709\u751f\u547d\u7279\u5f81\u7684\u201c\u4eba\u9020\u7ec6\u80de\u201d\u662f\u79d1\u5b66\u5bb6\u6267\u7740\u7684\u8ffd\u6c42\uff0c\u800c\u73b0\u5728\u6709\u751f\u7269\u5b66\u5bb6\u9884\u6d4b\uff1a\u7b2c\u4e00\u4e2a\u5168\u4eba\u5de5\u5408\u6210\u7684\u7ec6\u80de\u53ef\u80fd\u4f1a\u5728\u5341\u5e74\u5185\u51fa\u73b0\u3002\u5982\u679c\u8fd9\u4e2a\u7ec6\u80de\u8fd8\u80fd\u6210\u957f\u3001\u5206\u88c2\uff0c\u65e0\u7591\u90a3\u5c06\u662f\u4eba\u7c7b\u5de8\u5927\u7684\u8fdb\u6b65\u3002<\/span><\/p>\n


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Cell\u91cd\u78c5\uff1a\u5341\u5e74\u78e8\u4e00\u5251\uff0c\u79d1\u5b66\u5bb6\u6210\u529f\u5408\u6210\u51fa\u53ef\u6b63\u5e38\u751f\u957f\u5206\u88c2\u7684 \u201c\u4eba\u9020\u7ec6\u80de\u201d<\/span><\/strong><\/a>
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\u4eba\u5de5\u7ec6\u80de\u7684\u5408\u6210\u5bf9\u4e8e\u79d1\u5b66\u5bb6\u7406\u89e3\u751f\u547d\u4e0e\u57fa\u56e0\u7684\u5965\u79d8\u5177\u6709\u91cd\u8981\u610f\u4e49\u300220 \u591a\u5e74\u4ee5\u6765\uff0c\u4eba\u4eec\u4e00\u76f4\u5728\u5c1d\u8bd5\u5728\u5b9e\u9a8c\u5ba4\u4e2d\uff0c\u901a\u8fc7\u5c06\u4e00\u4e9b\u751f\u7269\u5206\u5b50\u62fc\u51d1\u8d77\u6765\u4ece\u800c\u521b\u9020\u51fa\u53ef\u4ee5\u81ea\u4e3b\u63a7\u5236\u3001\u4ee3\u8c22\u3001\u7ef4\u6301\u751f\u547d\u7684\u4eba\u9020\u7ec6\u80de\u3002\u800c\u73b0\u5728\uff0c\u8fd9\u4e00\u52aa\u529b\u7ec8\u4e8e\u53d6\u5f97\u4e86\u91cd\u8981\u7a81\u7834\u3002\u8fd1\u65e5\uff0c\u6765\u81ea\u7f8e\u56fd J. Craig Venter \u7814\u7a76\u6240\uff08JCVI\uff09\uff0c\u7f8e\u56fd\u56fd\u5bb6\u6807\u51c6\u4e0e\u6280\u672f\u7814\u7a76\u9662\uff08NIST\uff09\u4ee5\u53ca\u9ebb\u7701\u7406\u5de5\u5b66\u9662\uff08MIT\uff09\u7684\u7814\u7a76\u4eba\u5458\u5408\u4f5c\uff0c\u6210\u529f\u521b\u9020\u51fa\u4e86\u4e00\u4e2a\u975e\u5e38\u7b80\u5355\u7684\u4eba\u5de5\u5408\u6210\u7ec6\u80de\uff0c\u8be5\u7ec6\u80de\u53ef\u4ee5\u6b63\u5e38\u751f\u957f\u548c\u5206\u88c2\u3002<\/span><\/p>\n


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\u4eba\u5de5\u751f\u547d\u5165\u95e8\u8def\u5f84<\/span><\/strong><\/span><\/h4>\n

https:\/\/pattern.swarma.org\/article\/11<\/span><\/p>\n

\u96c6\u667a\u6591\u56fe\u4f5c\u8005JC\u6574\u7406\u4e86Lana Sinapayen\u4e3a\u4eba\u5de5\u667a\u80fd\u7814\u7a76\u8005\u4eec\u63d0\u4f9b\u7684\u4e00\u4efd\u4eba\u5de5\u751f\u547d\u5165\u95e8\u6307\u5357\u3002Lana Sinapayen\u662f\u7d22\u5c3c\u8ba1\u7b97\u673a\u79d1\u5b66\u5b9e\u9a8c\u5ba4\u548c\u4e1c\u4eac\u5730\u7403\u751f\u547d\u79d1\u5b66\u7814\u7a76\u6240\u7684\u4e00\u540d\u4eba\u5de5\u751f\u547d\u7814\u7a76\u8005\uff0c\u540c\u65f6\u4e5f\u662f\u56fd\u9645\u4eba\u5de5\u751f\u547d\u5b66\u4f1a\u7406\u4e8b\u4f1a\u6210\u5458\u3002<\/span><\/p>\n


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\u4f5c\u4e3a\u96c6\u667a\u767e\u79d1\u9879\u76ee\u56e2\u961f\u7684\u6210\u5458\uff0c\u672c\u6587\u5185\u5bb9\u7531<\/span><\/span><\/strong>\u5c0f\u7af9\u51c9<\/span><\/strong>\u7ffb\u8bd1<\/span>\uff0c<\/span>\u8584\u8377<\/span><\/strong>\u7f16\u8f91\u3002\u6211\u4eec\u4e5f\u4e3a\u6bcf\u4f4d\u4f5c\u8005\u548c\u5fd7\u613f\u8005\u51c6\u5907\u4e86\u4e13\u5c5e\u7b80\u4ecb\u548c\u4e2a\u4eba\u96c6\u667a\u767e\u79d1\u4e3b\u9875\uff0c\u66f4\u591a\u4fe1\u606f\u53ef\u4ee5\u8bbf\u95ee\u5176\u96c6\u667a\u767e\u79d1\u4e2a\u4eba\u4e3b\u9875\u3002<\/span><\/p>\n


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