{"id":37332,"date":"2022-09-16T22:17:44","date_gmt":"2022-09-16T14:17:44","guid":{"rendered":"https:\/\/swarma.org\/?p=37332"},"modified":"2022-09-16T22:17:44","modified_gmt":"2022-09-16T14:17:44","slug":"2%e4%ba%bf%e4%b8%aaalphafold%e9%a2%84%e6%b5%8b%e7%bb%93%e6%9e%84%e4%b8%ad%e9%9a%90%e8%97%8f%e7%9a%84%e8%9b%8b%e7%99%bd%e8%b4%a8%e8%bf%9b%e5%8c%96%e8%b6%8b%e5%8a%bf-%e9%9b%86%e6%99%ba%e7%a7%91","status":"publish","type":"post","link":"https:\/\/swarma.org\/?p=37332","title":{"rendered":"2\u4ebf\u4e2aAlphaFold\u9884\u6d4b\u7ed3\u6784\u4e2d\u9690\u85cf\u7684\u86cb\u767d\u8d28\u8fdb\u5316\u8d8b\u52bf | \u96c6\u667a\u79d1\u5b66\u5bb6\u6700\u65b0\u6210\u679c"},"content":{"rendered":"<div class='wxsyncmain'>\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;letter-spacing: 0.544px;white-space: normal;color: rgb(63, 63, 63);font-family: PingFangSC-light;font-size: 15px;background-color: rgb(255, 255, 255);visibility: visible;margin-bottom: 0px;\" data-mpa-powered-by=\"yiban.io\">\n<section style=\"outline: 0px;display: inline-block;width: 661px;vertical-align: top;background-color: rgb(246, 246, 246);visibility: visible;\">\n<section style=\"outline: 0px;visibility: visible;\">\n<p style=\"text-align: center;margin-bottom: 0em;\"><img class=\"rich_pages wxw-img\" data-backh=\"434\" data-backw=\"578\" data-galleryid=\"114734399718719488\" data-gallerysupplier=\"4\" data-ratio=\"0.75\" data-s=\"300,640\"  data-type=\"jpeg\" data-w=\"1280\" style=\"width: 100%;height: auto !important;\" src=\"\/wp-content\/uploads\/2022\/09\/wxsync-2022-09-7acbcce865b68d464c33063ed75cc782.jpeg\"  \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;outline: 0px;letter-spacing: 0.544px;visibility: visible;\">\n<section style=\"outline: 0px;width: 661px;visibility: visible;\">\n<section style=\"padding-right: 3px;outline: 0px;float: left;line-height: 1;visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;text-align: left;visibility: visible;\">\n<section style=\"padding-left: 10px;outline: 0px;display: inline-block;width: auto;vertical-align: top;min-width: 10%;height: auto;border-left: 3px solid rgb(33, 166, 210);border-bottom-left-radius: 0px;line-height: 0;visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;transform: translate3d(-13px, 0px, 0px);visibility: visible;\">\n<section style=\"outline: 0px;display: inline-block;width: 25px;height: 10px;vertical-align: top;overflow: hidden;line-height: 0;border-style: solid solid none;border-width: 3px 3px 2px;border-radius: 0px;border-color: rgb(33, 166, 210) rgb(33, 166, 210) rgb(15, 76, 129);visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;transform: translate3d(-1px, 0px, 0px);visibility: visible;\">\n<section style=\"outline: 0px;text-align: justify;color: rgb(33, 166, 210);font-size: 16px;line-height: 1.5;visibility: visible;\">\n<p style=\"outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;visibility: visible;\">\u5bfc\u8bed<\/strong><\/p>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;transform: translate3d(-13px, 0px, 0px) rotateX(180deg);visibility: visible;\">\n<section style=\"outline: 0px;display: inline-block;width: 24px;height: 10px;vertical-align: top;overflow: hidden;line-height: 0;border-style: solid solid none;border-width: 3px 3px 2px;border-radius: 0px;border-color: rgb(33, 166, 210) rgb(33, 166, 210) rgb(15, 76, 129);visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 4px;padding-left: 4px;outline: 0px;clear: right;box-shadow: rgb(0, 0, 0) 0px 0px 0px;visibility: visible;min-height: 4.5em !important;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 5px;margin-bottom: 5px;outline: 0px;visibility: visible;\">\n<section style=\"padding-right: 8px;padding-left: 8px;outline: 0px;font-size: 13px;line-height: 2;letter-spacing: 0.544px;visibility: visible;\">\n<p style=\"outline: 0px;clear: none;line-height: 2em;visibility: visible;\"><span style=\"line-height: 26px;font-weight: 700;min-height: 0px;background-image: none;background-clip: border-box;background-position: 0% 0%;background-repeat: repeat;background-size: auto;border-width: 0px;border-style: none;border-color: rgb(63, 63, 63);bottom: auto;height: auto;left: auto;max-height: none;min-width: 0px;top: auto;z-index: auto;visibility: visible;clear: none;color: rgb(63, 63, 63);font-size: 13px;letter-spacing: 0.544px;text-decoration: none solid rgb(63, 63, 63);\">\u7269\u79cd\u8fdb\u5316\u548c\u5206\u5b50\u8fdb\u5316\u662f\u8fdb\u5316\u751f\u7269\u5b66\u7814\u7a76\u7684\u4e24\u4e2a\u91cd\u8981\u4e3b\u9898\uff0c\u5b83\u4eec\u4e4b\u95f4\u662f\u5426\u5b58\u5728\u7740\u67d0\u79cd\u8054\u7cfb\uff1f\u8fd1\u65e5\uff0c\u65e5\u672c\u7406\u5316\u5b66\u7814\u7a76\u6240\u7814\u7a76\u79d1\u5b66\u5bb6\u3001\u96c6\u667a\u79d1\u5b66\u5bb6\u5510\u4e7e\u5143\u7b49\u4eba\uff0c\u5229\u7528\u4eba\u5de5\u667a\u80fd\u7cfb\u7edfAlphaFold\u9884\u6d4b\u7684\u86cb\u767d\u8d28\u7ed3\u6784\uff0c\u901a\u8fc7\u7edf\u8ba1\u7269\u7406\u5206\u6790\uff0c\u63ed\u793a\u51fa\u968f\u7740\u751f\u7269\u4f53\u590d\u6742\u5ea6\u7684\u63d0\u9ad8\uff0c\u751f\u7269\u4f53\u7684\u57fa\u672c\u7ec4\u6210\u5355\u5143\u2014\u2014\u86cb\u767d\u8d28\u5206\u5b50\u5728\u8fdb\u5316\u4e2d\u6240\u8868\u73b0\u51fa\u7684\u7edf\u8ba1\u8d8b\u52bf\u3002\u76f8\u5173\u6210\u679c\u53d1\u8868\u5728\u5206\u5b50\u751f\u7269\u5b66\u548c\u8fdb\u5316\u751f\u7269\u5b66\u9886\u57df\u7684\u77e5\u540d\u671f\u520a<em>Molecular Biology and Evolution<\/em>\u3002<\/span><\/p>\n<p style=\"outline: 0px;clear: none;line-height: 2em;visibility: visible;\"><br  \/><\/p>\n<p style=\"outline: 0px;clear: none;line-height: 2em;visibility: visible;\"><strong style=\"letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;caret-color: var(--weui-BRAND);\"><span style=\"outline: 0px;letter-spacing: 0.544px;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;color: rgb(63, 63, 63);font-family: PingFangSC-light;font-size: 13px;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;letter-spacing: 0.544px;orphans: 2;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;visibility: visible;\"><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;color: rgb(63, 63, 63);font-family: PingFangSC-light;font-size: 13px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(246, 246, 246);visibility: visible;\"><span style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;visibility: visible;\"><span style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;visibility: visible;\"><span style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;visibility: visible;\"><span style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;visibility: visible;\"><span style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;visibility: visible;\"><span style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;color: rgb(0, 0, 0);text-align: start;visibility: visible;\">\u7814\u7a76\u9886\u57df\uff1a\u751f\u7269\u8fdb\u5316\uff0c\u751f\u7269\u590d\u6742\u5ea6<\/strong><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/strong><\/strong><\/span><\/strong><\/span><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;outline: 0px;visibility: visible;\">\n<section style=\"outline: 0px;width: 661px;visibility: visible;\">\n<section style=\"outline: 0px;clear: both;line-height: 0;visibility: visible;\">\n<section style=\"outline: 0px;line-height: 0;width: 0px;visibility: visible;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align: top;visibility: visible;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;outline: 0px;letter-spacing: 0.544px;white-space: normal;color: rgb(63, 63, 63);font-family: PingFangSC-light;font-size: 15px;background-color: rgb(255, 255, 255);text-align: center;visibility: visible;\">\n<section style=\"outline: 0px;vertical-align: middle;display: inline-block;line-height: 0;visibility: visible;\"><img class=\"rich_pages wxw-img\" data-fileid=\"100098753\" data-ratio=\"0.07314814814814814\"  data-type=\"png\" data-w=\"1080\" style=\"outline: 0px;box-sizing: border-box;vertical-align: middle;visibility: visible !important;width: 677px !important;height: auto !important;\" src=\"\/wp-content\/uploads\/2022\/09\/wxsync-2022-09-e16cd5b776e38a4f6806c73548bdc7d4.png\"  \/><strong style=\"letter-spacing: 0.544px;text-align: right;font-size: 13px;outline: 0px;color: rgb(0, 0, 0);visibility: visible;\"><\/strong><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 0pt;margin-bottom: 0pt;outline: 0px;letter-spacing: 0.544px;white-space: normal;line-height: 1.7;font-family: PingFangSC-light;background-color: rgb(255, 255, 255);text-align: right;visibility: visible;\">\n<p style=\"outline: 0px;visibility: visible;\"><span style=\"font-family: PingFangSC-light;letter-spacing: 0.544px;text-align: right;background-color: rgb(255, 255, 255);outline: 0px;visibility: visible;\"><span style=\"outline: 0px;visibility: visible;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;font-family: PingFangSC-light;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;letter-spacing: 0.544px;orphans: 2;text-align: right;text-indent: 0px;text-transform: none;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-style: initial;text-decoration-color: initial;background-color: rgb(255, 255, 255);outline: 0px;visibility: visible;overflow-wrap: break-word !important;box-sizing: border-box !important;font-size: 13px;\"><span style=\"color:#494949;\">\u5085\u6e25\u6210<\/span><\/span><span style=\"color: rgb(0, 0, 0);font-size: 16px;font-weight: bold;margin: 0px;padding: 0px;max-width: 100%;font-family: PingFangSC-light;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;letter-spacing: 0.544px;orphans: 2;text-align: right;text-indent: 0px;text-transform: none;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-style: initial;text-decoration-color: initial;background-color: rgb(255, 255, 255);outline: 0px;visibility: visible;overflow-wrap: break-word !important;box-sizing: border-box !important;\">&nbsp;<\/span><span style=\"color: rgb(0, 0, 0);font-size: 13px;font-weight: bold;margin: 0px;padding: 0px;max-width: 100%;font-family: PingFangSC-light;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;letter-spacing: 0.544px;orphans: 2;text-align: right;text-indent: 0px;text-transform: none;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-style: initial;text-decoration-color: initial;background-color: rgb(255, 255, 255);outline: 0px;visibility: visible;overflow-wrap: break-word !important;box-sizing: border-box !important;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;color: rgb(0, 0, 0);visibility: visible;\">| \u4f5c\u8005<\/strong><\/span><\/span><\/span><span style=\"letter-spacing: 0.544px;outline-color: initial;outline-style: initial;\"><strong style=\"font-size: 13px;letter-spacing: 0.544px;outline: 0px;color: rgb(0, 0, 0);visibility: visible;\"><\/strong><\/span><\/p>\n<p style=\"color: rgb(73, 73, 73);outline: 0px;visibility: visible;\"><span style=\"font-size: 13px;letter-spacing: 0.544px;\">\u9093\u4e00\u96ea<\/span><strong style=\"font-size: 13px;letter-spacing: 0.544px;outline: 0px;color: rgb(0, 0, 0);visibility: visible;\"><span style=\"color: rgb(73, 73, 73);letter-spacing: 0.544px;outline: 0px;font-size: 16px;visibility: visible;\">&nbsp;<\/span><span style=\"color: rgb(73, 73, 73);letter-spacing: 0.544px;outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;color: rgb(0, 0, 0);visibility: visible;\">| <\/strong><\/span>\u7f16\u8f91<\/strong><\/p>\n<p style=\"color: rgb(73, 73, 73);font-size: 11pt;outline: 0px;visibility: visible;\"><br  \/><\/p>\n<\/section>\n<p style=\"text-align: center;margin-bottom: 0em;\"><span style=\"color: rgb(63, 63, 63);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 15px;letter-spacing: 0.544px;text-align: justify;background-color: rgb(255, 255, 255);\">&nbsp;<\/span><\/p>\n<section style=\"text-align: center;margin-bottom: 0em;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.4375\" data-s=\"300,640\"  data-type=\"png\" data-w=\"912\" style=\"height: auto !important;\" src=\"\/wp-content\/uploads\/2022\/09\/wxsync-2022-09-e30c74ef8927b45e4df16ec8a662d309.png\"  \/><\/section>\n<blockquote data-type=\"2\" data-url=\"\" data-author-name=\"\" data-content-utf8-length=\"147\" data-source-title=\"\" style=\"margin: 1em 0px;padding: 4px 0px 0px 10px;outline: 0px;border-left: 3px solid rgb(219, 219, 219);color: rgb(154, 154, 154);font-size: 15px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;line-height: 1.6;visibility: visible;\">\n<section style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible;\">\n<section style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible;\">\n<section style=\"margin: 0px 8px;padding: 0px;outline: 0px;max-width: 100%;clear: both;min-height: 1em;color: rgba(0, 0, 0, 0.5);text-align: left;visibility: visible;line-height: 1.5em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"color: rgb(136, 136, 136);\">\u8bba\u6587\u9898\u76ee\uff1a<\/span><\/section>\n<section style=\"margin: 0px 8px;padding: 0px;outline: 0px;max-width: 100%;clear: both;min-height: 1em;color: rgba(0, 0, 0, 0.5);text-align: left;visibility: visible;line-height: 1.5em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"color: rgb(136, 136, 136);\">The Statistical Trends of Protein Evolution: A Lesson from AlphaFold Database<\/span><\/section>\n<section style=\"margin: 0px 8px;padding: 0px;max-width: 100%;color: rgb(51, 51, 51);font-family: mp-quote, -apple-system-font, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;font-weight: 400;letter-spacing: normal;orphans: 2;text-indent: 0px;text-transform: none;white-space: normal;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;text-align: left;line-height: 1.5em;overflow-wrap: break-word !important;box-sizing: border-box !important;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;color: rgb(136, 136, 136);font-size: 15px;\">\u8bba\u6587\u94fe\u63a5\uff1a<\/span><\/section>\n<section style=\"margin: 0px 8px;padding: 0px;max-width: 100%;color: rgb(51, 51, 51);font-family: mp-quote, -apple-system-font, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;font-weight: 400;letter-spacing: normal;orphans: 2;text-indent: 0px;text-transform: none;white-space: normal;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;text-align: left;line-height: 1.5em;overflow-wrap: break-word !important;box-sizing: border-box !important;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;color: rgb(136, 136, 136);font-size: 15px;\">https:\/\/academic.oup.com\/mbe\/advance-article\/doi\/10.1093\/molbev\/msac197\/6701686<\/span><\/section>\n<\/section>\n<\/section>\n<\/blockquote>\n<p style=\"margin: 0px 8px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;clear: both;min-height: 1em;line-height: 1.75em;text-align: left;\"><br  \/><\/p>\n<section style=\"margin: 0px 8px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;line-height: 1.75em;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<h3 style=\"margin: 0px 0px 0em;padding: 0px;outline: 0px;font-weight: 400;font-size: 16px;max-width: 100%;color: rgb(51, 51, 51);font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;font-family: mp-quote, -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);visibility: visible;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section powered-by=\"xiumi.us\" style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;letter-spacing: 0.544px;text-align: right;font-size: 13px;visibility: visible;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section powered-by=\"xiumi.us\" style=\"margin: 10px 0px;padding: 0px;outline: 0px;max-width: 100%;letter-spacing: 0.544px;text-align: center;visibility: visible;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;display: inline-block;vertical-align: middle;visibility: visible;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin: 0px 0px -2px;padding: 0px;outline: 0px;max-width: 100%;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;visibility: visible;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible;\"  \/><\/section>\n<section style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible;\"  \/><\/section>\n<section style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;clear: both;line-height: 0;visibility: visible;\">\n<section style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;line-height: 0;width: 0px;visibility: visible;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align: top;visibility: visible;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"margin: 0px;padding: 0px 10px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;border-left: 3px solid rgb(33, 166, 210);border-right: 3px solid rgb(33, 166, 210);border-top-color: rgb(33, 166, 210);border-bottom-color: rgb(33, 166, 210);font-size: 16px;color: rgb(0, 0, 0);line-height: 1.4;visibility: visible;\">\n<p style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;clear: both;min-height: 1em;visibility: visible;\"><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible;\"><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;text-align: left;color: rgb(33, 166, 210);letter-spacing: 0.544px;visibility: visible;\"><span style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;caret-color: rgb(89, 89, 89);visibility: visible;\">1. \u7269\u79cd\u8fdb\u5316\u4e0e\u5206\u5b50\u8fdb\u5316<\/span><\/strong><\/strong><\/p>\n<\/section>\n<section style=\"margin: -2px 0px 0px;padding: 0px;outline: 0px;max-width: 100%;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;visibility: visible;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible;\"  \/><\/section>\n<section style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n<section style=\"margin: 0px 8px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;color: rgb(51, 51, 51);font-family: mp-quote, -apple-system-font, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;font-weight: 400;letter-spacing: normal;orphans: 2;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;line-height: 1.75em;\"><br  \/><\/section>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5c3d\u7ba1\u5e76\u4e0d\u5b58\u5728\u7740\u67d0\u79cd\u56fa\u5b9a\u7684\u201c\u8fdb\u5316\u65b9\u5411\u201d\uff0c\u4f46\u4ece<strong>\u5b8f\u89c2\u5c3a\u5ea6<\/strong>\u6765\u770b\uff0c\u7684\u786e\u53ef\u4ee5\u770b\u5230\u751f\u547d\u7684<strong>\u590d\u6742\u6027<\/strong>\u5728\u6f2b\u957f\u7684\u8fdb\u5316\u8fc7\u7a0b\u4e2d\u4e0d\u65ad\u589e\u52a0\uff0c\u4f8b\u5982\u4ece\u539f\u6838\u751f\u7269\u5230\u771f\u6838\u751f\u7269\uff0c\u4ece\u5355\u7ec6\u80de\u751f\u7269\u5230\u591a\u7ec6\u80de\u751f\u7269\u7b49\u7b49\u3002\u5728<strong>\u5fae\u89c2\u5c3a\u5ea6<\/strong>\u4e0b\uff0c\u4e0e\u751f\u7269\u4f53\u7684\u590d\u6742\u5316\u5e76\u884c\u53d1\u751f\u7740\u53e6\u4e00\u79cd\u8fdb\u5316\u8fc7\u7a0b\uff0c\u90a3\u5c31\u662f\u5206\u5b50\u8fdb\u5316\uff0c\u5373\u4f5c\u4e3a\u751f\u7269\u4f53\u57fa\u672c\u6784\u4ef6\u7684\u86cb\u767d\u8d28\u5206\u5b50\u4e5f\u5728\u4e0d\u65ad\u8fdb\u5316\u3002\u8fdb\u5316\u7684\u8fd9\u79cd\u5b8f\u89c2<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u751f\u7269\u4f53\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u4e0e\u5fae\u89c2<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u86cb\u767d\u8d28\u5206\u5b50\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u89c6\u89d2\u4e4b\u95f4\u662f\u5426\u5b58\u5728\u67d0\u79cd\u8054\u7cfb\uff1f\u76f4\u89c2\u4e0a\u6765\u770b\uff0c\u67d0\u79cd\u7279\u5b9a\u7684\u86cb\u767d\u8d28\u5206\u5b50\u7684\u8fdb\u5316\u4e0d\u4e00\u5b9a\u9075\u5faa\u7269\u79cd\u8fdb\u5316\u7684\u8def\u5f84\uff0c\u7136\u800c\uff0c\u5982\u679c\u628a\u89c6\u89d2\u6269\u5c55\u5230\u5927\u91cf\u86cb\u767d\u8d28\u7684\u96c6\u5408\u3001<strong>\u751a\u81f3\u662f\u4e00\u4e2a\u751f\u7269\u4f53\u5185\u7684\u5168\u90e8\u86cb\u767d\u8d28<\/strong>\uff0c\u6216\u8bb8\u80fd\u4ece\u4e2d\u6316\u6398\u51fa\u67d0\u4e9b\u96c6\u4f53\u7279\u5f81\uff0c\u53cd\u6620\u51fa\u4e0e\u751f\u7269\u4f53\u590d\u6742\u6027\u76f8\u4e00\u81f4\u7684<strong>\u7edf\u8ba1\u8d8b\u52bf<\/strong>\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u4e0a\u8ff0\u8fd9\u79cd\u5b8f\u89c2\u4e0e\u5fae\u89c2\u4e4b\u95f4\u7684\u8054\u7cfb\u4e0e\u7ecf\u5178\u7684\u7edf\u8ba1\u7269\u7406\u95ee\u9898\u7c7b\u4f3c\uff1a\u4ece\u5fae\u89c2\u51fa\u53d1\uff0c\u89c2\u5bdf\u6c14\u4f53\u5206\u5b50\u7684\u8fd0\u52a8\uff0c\u4f1a\u53d1\u73b0\u5176\u8fd0\u52a8\u6742\u4e71\u65e0\u7ae0\uff0c\u770b\u4f3c\u6beb\u65e0\u79e9\u5e8f\uff1b\u82e5\u662f\u5207\u6362\u5230\u5b8f\u89c2\u89c6\u89d2\uff0c\u5c06\u6574\u4e2a\u7cfb\u7edf\u7528\u5c11\u6570\u51e0\u4e2a\u70ed\u529b\u5b66\u91cf<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u5982\u538b\u5f3a\u3001\u6e29\u5ea6\u7b49\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u6765\u63cf\u8ff0\uff0c\u5219\u80fd\u53d1\u73b0\u7cfb\u7edf\u67d0\u79cd\u201c\u96c6\u4f53\u6027\u201d\u7684\u6f14\u5316\u8d8b\u52bf\u3002\u5982\u679c\u80fd\u4ece\u5927\u91cf\u7684\u5fae\u89c2\u4e2a\u4f53\u7684\u6f14\u5316<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u5373\u86cb\u767d\u8d28\u7684\u8fdb\u5316\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u4e2d\u63d0\u53d6\u51fa\u4e0e\u7cfb\u7edf\u5b8f\u89c2\u6f14\u5316\u65b9\u5411<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u5373\u7269\u79cd\u6f14\u5316\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u76f8\u4e00\u81f4\u7684\u8d8b\u52bf\uff0c\u5c31\u80fd\u5bf9\u751f\u547d\u7684\u8d77\u6e90\u548c\u8fdb\u5316\u95ee\u9898\u6709\u5168\u65b0\u7684\u8ba4\u8bc6\u3002\u4e0d\u8fc7\u5728\u5f88\u957f\u7684\u4e00\u6bb5\u65f6\u95f4\u91cc\uff0c\u7531\u4e8e\u5df2\u77e5\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u4ecd\u7136\u975e\u5e38\u6709\u9650\uff0c\u96be\u4ee5\u771f\u6b63\u8ba8\u8bba\u7269\u79cd\u4f53\u5185\u86cb\u767d\u8d28\u6574\u4f53\u8fdb\u5316\u8d8b\u52bf\u3002\u5e78\u8fd0\u7684\u662f\uff0c\u6700\u8fd1\u4eba\u5de5\u667a\u80fd\u7684\u53d1\u5c55\u4e3a\u7814\u7a76\u8005\u4eec\u63d0\u4f9b\u4e86\u5168\u65b0\u7684\u5f3a\u5927\u7684\u5de5\u5177\uff0c\u8ba9\u4e0a\u8ff0\u7814\u7a76\u601d\u8def\u80fd\u591f\u771f\u6b63\u5f97\u4ee5\u5b9e\u73b0\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8fd1\u65e5\uff0c\u65e5\u672c\u7406\u5316\u5b66\u7814\u7a76\u6240<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08RIKEN\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5510\u4e7e\u5143<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08aka \u5085\u6e25\u6210\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u535a\u58eb\u548c\u4efb\u536b\u540c\u535a\u58eb\u3001\u4e0e\u5357\u4eac\u5927\u5b66\u738b\u9a8f\u6559\u6388\u3001\u4e39\u9ea6\u54e5\u672c\u54c8\u6839\u5927\u5b66\u91d1\u5b50\u90a6\u5f66<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08Kunihiko Kaneko\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u6559\u6388\u5408\u4f5c\uff0c\u57fa\u4e8e\u4eba\u5de5\u667a\u80fd\u7cfb\u7edfAlphaFold \u9884\u6d4b\u7684\u86cb\u767d\u8d28\u7ed3\u6784\uff0c\u901a\u8fc7\u7edf\u8ba1\u7269\u7406\u5206\u6790\uff0c\u63ed\u793a\u51fa\u968f\u7740\u751f\u7269\u4f53\u590d\u6742\u5ea6\u7684\u63d0\u9ad8\uff0c\u751f\u7269\u4f53\u7684\u57fa\u672c\u7ec4\u6210\u5355\u5143\u2014\u2014\u86cb\u767d\u8d28\u5206\u5b50\u5728\u8fdb\u5316\u4e2d\u6240\u8868\u73b0\u51fa\u7684\u7edf\u8ba1\u8d8b\u52bf\u3002\u8fd9\u4e00\u7814\u7a76\u662f\u9996\u6b21\u5bf940\u591a\u79cd\u751f\u7269\u4f53\u5185\u86cb\u767d\u8d28\u7ec4\u5185\u7684\u5168\u90e8\u86cb\u767d\u8d28\u7ed3\u6784\u8fdb\u884c\u7edf\u8ba1\u5206\u6790\uff0c\u8be5\u5de5\u4f5c\u53d1\u8868\u5728\u5206\u5b50\u751f\u7269\u5b66\u548c\u8fdb\u5316\u751f\u7269\u5b66\u9886\u57df\u7684\u77e5\u540d\u671f\u520a&nbsp;<em>Molecular Biology and Evolution<\/em><\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff082021 IF: 8.8\uff0c\u4e2d\u79d1\u96621\u533aTop\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><strong><br  \/><\/strong><\/span><\/p>\n<h3 style=\"margin-bottom: 0em;outline: 0px;color: rgb(34, 34, 34);letter-spacing: 0.544px;white-space: normal;font-family: mp-quote, -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;letter-spacing: 0.544px;text-align: right;font-size: 13px;visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;outline: 0px;letter-spacing: 0.544px;text-align: center;visibility: visible;\">\n<section style=\"outline: 0px;display: inline-block;vertical-align: middle;visibility: visible;\">\n<section style=\"margin-bottom: -2px;outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;visibility: visible;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;clear: both;line-height: 0;visibility: visible;\">\n<section style=\"outline: 0px;line-height: 0;width: 0px;visibility: visible;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align: top;visibility: visible;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 10px;padding-left: 10px;outline: 0px;border-left: 3px solid rgb(33, 166, 210);border-right: 3px solid rgb(33, 166, 210);border-top-color: rgb(33, 166, 210);border-bottom-color: rgb(33, 166, 210);font-size: 16px;color: rgb(0, 0, 0);line-height: 1.4;visibility: visible;\">\n<p style=\"outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;text-align: left;color: rgb(33, 166, 210);letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;caret-color: rgb(89, 89, 89);visibility: visible;\">2. AlphaFold\u6570\u636e\u5e93<\/span><\/strong><\/strong><\/p>\n<\/section>\n<section style=\"margin-top: -2px;outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;visibility: visible;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">2021 \u5e74\uff0c<em>Science&nbsp;<\/em>\u548c&nbsp;<em>Nature&nbsp;<\/em>\u6742\u5fd7\u4e0d\u7ea6\u800c\u540c\u5730\u5c06\u201c\u5e74\u5ea6\u5341\u5927\u79d1\u5b66\u7a81\u7834\u201d\u9881\u7ed9\u4e86\u7531 Google DeepMind \u5f00\u53d1\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u7cfb\u7edf AlphaFold 2\u3002AlphaFold\u4f5c\u4e3aDeepMind\u5f00\u53d1\u7684\u4eba\u5de5\u667a\u80fd\u7cfb\u7edf\uff0c\u80fd\u591f\u5229\u7528\u5171\u8fdb\u5316<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08coevolution\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u4fe1\u606f\u63d0\u4f9b\u9ad8\u51c6\u786e\u5ea6\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\uff0c\u5e76\u4e14\u5728\u6b64\u524d\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u7ade\u8d5b\u4e2d\u4e2d\u8d62\u5f97\u4e86\u524d\u6240\u672a\u6709\u7684\u538b\u5012\u6027\u6210\u529f [1, 2]\u3002\u4ece2021\u5e74\u5f00\u59cb\uff0cAlphaFold\u53d1\u5e03\u4e86\u81ea\u5df1\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u6570\u636e\u5e93<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08AlphaFold Protein Structure Database\uff0c\u4ee5\u4e0b\u7b80\u79f0AlphaFold DB\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\uff0c\u5176\u4e2d\u5305\u542b\u4e86\u4ece\u7ec6\u83cc\u3001\u53e4\u7ec6\u83cc\u3001\u5355\u7ec6\u80de\u548c\u591a\u7ec6\u80de\u771f\u6838\u751f\u7269\u5230\u4eba\u7c7b\u7b49\u5728\u5185\u7684\u8bb8\u591a\u7269\u79cd\u7684\u5b8c\u6574\u86cb\u767d\u8d28\u7ec4\uff0c\u8fd9\u4e2a\u6570\u636e\u5e93\u8fd8\u5728\u4e0d\u65ad\u6269\u5927\uff0c\u57282022\u5e747\u6708\u5e95\u7684\u66f4\u65b0\u4e2d\uff0cAlphaFold DB\u5df2\u7ecf\u6269\u5145\u5230\u5305\u542b\u7ea62\u4ebf\u4e2a\u9884\u6d4b\u7684\u86cb\u767d\u8d28\u7ed3\u6784 [3, 4]\u3002AlphaFold DB\u4e0d\u4ec5\u80fd\u5e2e\u52a9\u79d1\u5b66\u5bb6\u4eec\u89e3\u51b3\u533b\u5b66\u548c\u751f\u547d\u79d1\u5b66\u4e2d\u7684\u5173\u952e\u95ee\u9898\uff0c\u800c\u4e14\u5728\u8fdb\u5316\u7814\u7a76\u4e2d\u663e\u793a\u51fa\u4e86\u65b0\u7684\u53ef\u80fd\u6027\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;text-align: center;\"><img class=\"rich_pages wxw-img\" data-ratio=\"0.6240740740740741\"  data-type=\"png\" data-w=\"1080\" style=\"height: auto !important;\" src=\"\/wp-content\/uploads\/2022\/09\/wxsync-2022-09-7692793036cd0c830eea2d12a240e121.png\"  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;margin-bottom: 0px;line-height: 1.5em;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe1. \u7814\u7a76\u601d\u8def\u793a\u610f\u56fe\u3002\u5229\u7528AlphaFold \u86cb\u767d\u8d28\u7ed3\u6784\u6570\u636e\u5e93\uff0c\u5efa\u7acb\u8d77\u7269\u79cd\u8fdb\u5316\u4e0e\u5206\u5b50\u8fdb\u5316\u4e4b\u95f4\u7684\u8054\u7cfb\u3002<\/span><\/section>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u4e0e\u4f20\u7edf\u7684\u5206\u5b50\u8fdb\u5316\u7814\u7a76\u4e0d\u540c\uff0c\u5510\u4e7e\u5143\u535a\u58eb\u53ca\u5176\u5408\u4f5c\u8005\u5229\u7528 AlphaFold DB \u53d1\u5c55\u4e86\u4e00\u5957\u57fa\u4e8e\u7269\u79cd\u5168\u86cb\u767d\u8d28\u7ec4\u86cb\u767d\u7ed3\u6784\u7684\u8fdb\u5316\u5206\u6790\u65b9\u6cd5\uff0c\u5bf9\u4e0d\u540c\u751f\u7269\u4f53\u5185\u7684<strong>\u5168\u90e8<\/strong>\u86cb\u767d\u8d28\u8fdb\u884c\u7edf\u8ba1\u6027\u7684\u7814\u7a76\uff0c\u800c\u4e0d\u662f\u53ea\u5173\u6ce8\u7279\u5b9a\u7684\u86cb\u767d\u8d28\u5bb6\u65cf\u3002\u7814\u7a76\u8005\u4eec\u4ece\u5e8f\u5217\u3001\u7ed3\u6784\u3001\u6c28\u57fa\u9178\u6b8b\u57fa\u7684\u62d3\u6251\u3001\u86cb\u767d\u8d28\u5e73\u8861\u6001\u7684\u52a8\u529b\u5b66\u7b49\u89d2\u5ea6\u51fa\u53d1\uff0c\u63ed\u793a\u4e86\u968f\u7740\u7269\u79cd\u671d\u7740\u66f4\u4e3a\u590d\u6742\u5316\u7684\u65b9\u5411\u8fdb\u5316\u3001\u7269\u79cd\u4f53\u5185\u7684\u86cb\u767d\u8d28\u5448\u73b0\u51fa\u7684\u6574\u4f53\u8fdb\u5316\u8d8b\u52bf\u3002\u4e0b\u9762\uff0c\u672c\u6587\u5c06\u4e3b\u8981\u4ece\u7269\u7406\u5b66\u56fe\u50cf\u7684\u89d2\u5ea6\u51fa\u53d1\uff0c\u7b80\u8981\u4ecb\u7ecd\u8fd9\u4e9b\u8fdb\u5316\u4e2d\u7684\u7edf\u8ba1\u8d8b\u52bf\u3002\u5982\u679c\u4f60\u5bf9\u5173\u4e8e\u751f\u547d\u590d\u6742\u6027\u7684\u5ef6\u4f38\u8ba8\u8bba\u66f4\u611f\u5174\u8da3\uff0c\u53ef\u4ee5\u76f4\u63a5\u8df3\u5230\u672c\u6587\u7684\u7b2c6\u5c0f\u8282\u3002\u5982\u679c\u4f60\u5bf9\u4e8e\u76f8\u5173\u7684\u7814\u7a76\u7ec6\u8282\u4e0e\u5206\u6790\u65b9\u6cd5\u611f\u5174\u8da3\uff0c\u9664\u4e86\u9605\u8bfb\u7b2c3~5\u8282\u7684\u8ba8\u8bba\u4ee5\u5916\uff0c\u4e5f\u53ef\u4ee5\u70b9\u51fb\u6587\u7ae0\u5f00\u5934\u7684\u201c\u8bba\u6587\u94fe\u63a5\u201d\uff0c\u76f4\u63a5\u9605\u8bfb\u8bba\u6587\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><strong><br  \/><\/strong><\/span><\/p>\n<h3 style=\"margin-bottom: 0em;outline: 0px;color: rgb(34, 34, 34);letter-spacing: 0.544px;white-space: normal;font-family: mp-quote, -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;letter-spacing: 0.544px;text-align: right;font-size: 13px;visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;outline: 0px;letter-spacing: 0.544px;text-align: center;visibility: visible;\">\n<section style=\"outline: 0px;display: inline-block;vertical-align: middle;visibility: visible;\">\n<section style=\"margin-bottom: -2px;outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;visibility: visible;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;clear: both;line-height: 0;visibility: visible;\">\n<section style=\"outline: 0px;line-height: 0;width: 0px;visibility: visible;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align: top;visibility: visible;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 10px;padding-left: 10px;outline: 0px;border-left: 3px solid rgb(33, 166, 210);border-right: 3px solid rgb(33, 166, 210);border-top-color: rgb(33, 166, 210);border-bottom-color: rgb(33, 166, 210);font-size: 16px;color: rgb(0, 0, 0);line-height: 1.4;visibility: visible;\">\n<p style=\"outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;text-align: left;color: rgb(33, 166, 210);letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;caret-color: rgb(89, 89, 89);visibility: visible;\">3. \u7ed3\u6784\u67d4\u6027<\/span><\/strong><\/strong><\/p>\n<\/section>\n<section style=\"margin-top: -2px;outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;visibility: visible;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u7814\u7a76\u8005\u4eec\u9996\u5148\u5bf9\u4e0d\u540c\u751f\u7269\u4f53\u5185\u3001\u94fe\u957f\u76f8\u8fd1\u7684\u86cb\u767d\u8d28\u5206\u5b50\u7684\u7ed3\u6784\u8fdb\u884c\u4e86\u5bf9\u6bd4\u5206\u6790\u3002\u5c3d\u7ba1\u9009\u53d6\u7684\u8fd9\u4e9b\u86cb\u767d\u8d28\u94fe\u957f\u63a5\u8fd1\uff0c\u4f46\u5728\u4e0d\u540c\u751f\u7269\u4f53\u5185\uff0c\u8fd9\u4e9b\u86cb\u767d\u8d28\u5206\u5b50\u7684\u56de\u8f6c\u534a\u5f84<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08radius of gyration\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5206\u5e03\u5374\u975e\u5e38\u4e0d\u540c<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u5982\u56fe2A\u6240\u793a\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002\u4f8b\u5982\uff0c\u5728\u5927\u80a0\u6746\u83cc<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08<em>E. coli<\/em>\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u4f53\u5185\u94fe\u957f\u7ea6\u4e3a250\u4e2a\u6c28\u57fa\u9178\u7684\u86cb\u767d\u8d28\uff0c\u5e73\u5747\u7684\u56de\u8f6c\u534a\u5f84\u5927\u7ea6\u4e3a20 \u00c5\uff0c\u800c\u5728\u4eba\u7c7b\u4f53\u5185\u76f8\u8fd1\u94fe\u957f\u7684\u86cb\u767d\u8d28\u7684\u5e73\u5747\u56de\u8f6c\u534a\u5f84\u5374\u63a5\u8fd130 \u00c5\uff0c\u4e24\u4e2a\u590d\u6742\u5ea6\u5dee\u5f02\u5de8\u5927\u7684\u7269\u79cd\u4f53\u5185\u7684\u86cb\u767d\u8d28\u534a\u5f84\u5206\u5e03\u4e5f\u6709\u663e\u8457\u7684\u7edf\u8ba1\u5dee\u5f02\u3002\u7531\u4e8e\u662f\u5728\u5bf9<strong>\u76f8\u8fd1\u94fe\u957f<\/strong>\u7684\u86cb\u767d\u8d28\u8fdb\u884c\u6bd4\u8f83\uff0c\u8fd9\u65f6\uff0c\u66f4\u5927\u7684\u56de\u8f6c\u534a\u5f84\u4e3b\u8981\u662f\u8ddf\u86cb\u767d\u8d28\u7ed3\u6784\u4e2d\u7ed3\u6784\u6da8\u843d\u8f83\u5927\u7684\u67d4\u6027\u7247\u6bb5\u76f8\u5173\uff0c\u56e0\u6b64\uff0c\u8fd9\u4e00\u7ed3\u679c\u8fd8\u8868\u660e\u4eba\u4f53\u5185\u7684\u86cb\u767d\u8d28\u6bd4\u5927\u80a0\u6746\u83cc\u4f53\u5185\u86cb\u767d\u8d28\u6709\u66f4\u9ad8\u7684\u67d4\u6027\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;text-align: center;\"><img class=\"rich_pages wxw-img\" data-ratio=\"0.4103585657370518\"  data-type=\"png\" data-w=\"1004\" style=\"height: auto !important;\" src=\"\/wp-content\/uploads\/2022\/09\/wxsync-2022-09-923693de39a939285ee54cf38a3195b1.png\"  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;margin-bottom: 0px;line-height: 1.5em;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe2. \u968f\u7740\u7269\u79cd\u590d\u6742\u5ea6\u7684\u589e\u52a0\uff0c\u5176\u4f53\u5185\u4e00\u5b9a\u94fe\u957f\u7684\u86cb\u767d\u8d28\u7684\u56de\u8f6c\u534a\u5f84\uff08\u53cd\u6620\u7ed3\u6784\u7684\u67d4\u6027\uff09\u4f1a\u76f8\u5e94\u589e\u52a0\u3002<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><\/span><\/section>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5bf9\u4e0d\u540c\u7269\u79cd\u4f53\u5185\u7684\u94fe\u957f\u76f8\u8fd1\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u8fdb\u884c\u7edf\u8ba1\uff0c\u4f1a\u53d1\u73b0\u4e00\u4e2a\u7c97\u7565\u7684\u76f8\u5173\u5173\u7cfb\uff1a\u968f\u7740\u7269\u79cd\u590d\u6742\u5ea6\u7684\u63d0\u9ad8\uff0c\u8be5\u7269\u79cd\u4f53\u5185\u7684\u86cb\u767d\u8d28\u7684\u56de\u8f6c\u534a\u5f84\u76f8\u5e94\u5730\u4f1a\u51fa\u73b0\u589e\u5927\u7684\u8d8b\u52bf\u3002\u8fd9\u91cc\u6d89\u53ca\u5230\u4e86\u201c\u590d\u6742\u5ea6\u201d\u7684\u6982\u5ff5\uff0c\u5c3d\u7ba1\u590d\u6742\u6027\u7684\u6570\u5b66\u5b9a\u4e49\u4ecd\u6709\u4e89\u8bae\uff0c\u4f46\u5927\u5bb6\u5bf9\u4e8e\u751f\u7269\u4f53\u672c\u8eab\u7684\u590d\u6742\u6027\u4ecd\u7136\u4f1a\u6709\u8bb8\u591a\u76f4\u89c2\u7684\u7406\u89e3<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u4f8b\u5982\u771f\u6838\u751f\u7269\u6bd4\u539f\u6838\u751f\u7269\u66f4\u590d\u6742\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002\u5728\u5b9e\u9645\u64cd\u4f5c\u4e2d\uff0c\u751f\u7269\u5b66\u5bb6\u4eec\u5f80\u5f80\u4f1a\u5bf9\u751f\u7269\u4f53\u7684\u590d\u6742\u6027\u5f15\u5165\u4e0d\u540c\u7684\u8861\u91cf\u6807\u51c6\uff0c\u4f8b\u5982\u751f\u7269\u4f53\u5185\u7684\u5404\u79cd\u7ec6\u80de\u7c7b\u578b\u7684\u603b\u6570\u3001\u57fa\u56e0\u7ec4\u5927\u5c0f\u3001\u86cb\u767d\u8d28\u7ec4\u5927\u5c0f\u7b49\u7b49\u3002\u8fd9\u4e9b\u5b9a\u4e49\u5206\u522b\u4fa7\u91cd\u4e8e\u751f\u7269\u590d\u6742\u5ea6\u7684\u4e0d\u540c\u5c42\u9762\uff0c\u8fd9\u4e9b\u4e0d\u540c\u7684\u5ea6\u91cf\u4e4b\u95f4\u5f80\u5f80\u4e5f\u662f\u76f8\u4e92\u5173\u8054\u7684 [5]\u3002\u5728\u672c\u7814\u7a76\u4e2d\uff0c\u7814\u7a76\u8005\u4eec\u57fa\u4e8e\u86cb\u767d\u8d28\u7ec4\u7684\u6570\u636e\uff0c\u5f15\u5165\u4e86\uff1a\uff081\uff09\u4e00\u4e2a\u751f\u7269\u4f53\u5185\u6240\u6709\u7684\u86cb\u767d\u8d28\u79cd\u7c7b\u6570\uff0c\u4ee5\u53ca\uff082\uff09\u5404\u79cd\u4e0d\u540c\u86cb\u767d\u8d28\u7684\u603b\u94fe\u957f\u4f5c\u4e3a\u751f\u7269\u590d\u6742\u6027\u7684\u5ea6\u91cf\u3002\u5982\u56fe2B\u6240\u793a\uff0c\u8fd9\u4e24\u79cd\u751f\u7269\u590d\u6742\u5ea6\u7684\u5ea6\u91cf\u90fd\u4e0e\u4e00\u5b9a\u94fe\u957f\u7684\u86cb\u767d\u8d28\u7684\u56de\u8f6c\u534a\u5f84\u6210\u6b63\u6bd4\uff0c\u8bc1\u660e\u968f\u7740\u7269\u79cd\u590d\u6742\u5ea6\u7684\u63d0\u9ad8\uff0c\u5176\u4f53\u5185\u7684\u86cb\u767d\u8d28\u8868\u73b0\u51fa\u66f4\u9ad8\u7684\u67d4\u6027\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5728\u8bba\u6587\u4e2d\uff0c\u7814\u7a76\u8005\u4e0d\u4ec5\u8ba8\u8bba\u4e86\u5176\u5b83\u94fe\u957f\u7684\u60c5\u51b5\uff0c\u8fd8\u5bf9AlphaFold\u9884\u6d4b\u7684\u7ed3\u6784\u7cbe\u5ea6\u8fdb\u884c\u4e86\u8fdb\u4e00\u6b65\u7684\u7b5b\u9009\uff0c\u800c\u4e14\u8fd8\u5bf9\u86cb\u767d\u8d28\u7684\u4e8c\u7ea7\u7ed3\u6784<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u5e38\u89c1\u7684\u4e8c\u7ea7\u7ed3\u6784\u5305\u542b\u03b1\u87ba\u65cb\u3001\u03b2\u6298\u53e0\u3001\u65e0\u89c4\u5377\u66f2\u7b49\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8fdb\u884c\u4e86\u5206\u6790\uff0c\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u4e86\u201c\u751f\u7269\u4f53\u590d\u6742\u5ea6\u4e0e\u5176\u4f53\u5185\u86cb\u767d\u8d28\u7684\u5e73\u5747\u67d4\u6027\u6210\u6b63\u76f8\u5173\u5173\u7cfb\u201d\u7684\u7ed3\u8bba\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><strong><br  \/><\/strong><\/span><\/p>\n<h3 style=\"margin-bottom: 0em;outline: 0px;color: rgb(34, 34, 34);letter-spacing: 0.544px;white-space: normal;font-family: mp-quote, -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;letter-spacing: 0.544px;text-align: right;font-size: 13px;visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;outline: 0px;letter-spacing: 0.544px;text-align: center;visibility: visible;\">\n<section style=\"outline: 0px;display: inline-block;vertical-align: middle;visibility: visible;\">\n<section style=\"margin-bottom: -2px;outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;visibility: visible;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;clear: both;line-height: 0;visibility: visible;\">\n<section style=\"outline: 0px;line-height: 0;width: 0px;visibility: visible;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align: top;visibility: visible;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 10px;padding-left: 10px;outline: 0px;border-left: 3px solid rgb(33, 166, 210);border-right: 3px solid rgb(33, 166, 210);border-top-color: rgb(33, 166, 210);border-bottom-color: rgb(33, 166, 210);font-size: 16px;color: rgb(0, 0, 0);line-height: 1.4;visibility: visible;\">\n<p style=\"outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;text-align: left;color: rgb(33, 166, 210);letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;caret-color: rgb(89, 89, 89);visibility: visible;\">4. \u5e8f\u5217\u548c\u62d3\u6251<\/span><\/strong><\/strong><\/p>\n<\/section>\n<section style=\"margin-top: -2px;outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;visibility: visible;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8981\u66f4\u6df1\u5165\u5730\u5206\u6790\u86cb\u767d\u8d28\u7684\u7ed3\u6784\uff0c\u9664\u4e86\u5bf9\u86cb\u767d\u8d28\u7684\u4e8c\u7ea7\u7ed3\u6784\u3001\u4e09\u7ea7\u7ed3\u6784\u8fdb\u884c\u5206\u6790\u4ee5\u5916\uff0c\u4e5f\u53ef\u4ee5\u5c06\u86cb\u767d\u8d28\u89c6\u4e3a\u6c28\u57fa\u9178\u6b8b\u57fa\u5728\u7a7a\u95f4\u4e2d\u76f8\u4e92\u9760\u8fd1\u63a5\u89e6\u800c\u5f62\u6210\u7684\u7f51\u7edc\uff0c\u7528\u7f51\u7edc\u62d3\u6251\u5206\u6790\u7684\u65b9\u6cd5\u6765\u5206\u6790\u86cb\u767d\u8d28\u7684\u6027\u8d28\u3002\u5728\u6b8b\u57fa\u63a5\u89e6\u7f51\u7edc<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08residue contact network\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u4e2d\uff0c\u6bcf\u4e2a\u8282\u70b9\u6240\u4ee3\u8868\u4e00\u4e2a\u6c28\u57fa\u9178\u6b8b\u57fa\uff0c\u6b8b\u57fa\u7a7a\u95f4\u8ddd\u79bb\u5c0f\u4e8e\u4e00\u5b9a\u7684\u622a\u65ad\u957f\u5ea6\u7684\uff0c\u5219\u88ab\u89c6\u4f5c\u5b58\u5728\u8fde\u8fb9\u3002\u5728\u8bba\u6587\u4e2d\uff0c\u7814\u7a76\u8005\u4eec\u5bf9\u4e8e\u8fd9\u4e2a\u7f51\u7edc\u7684\u8bb8\u591a\u62d3\u6251\u6027\u8d28\u8fdb\u884c\u4e86\u5206\u6790\uff0c\u5176\u4e2d\u4e0e\u86cb\u767d\u8d28\u7684\u7269\u7406\u6027\u8d28\u6700\u4e3a\u76f8\u5173\u7684\u5ea6\u91cf\u662f\u7f51\u7edc\u7684<strong>\u540c\u914d\u6027<\/strong><\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08assortativity\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;text-align: center;\"><img class=\"rich_pages wxw-img\" data-ratio=\"0.28941176470588237\"  data-type=\"png\" data-w=\"850\" style=\"height: auto !important;\" src=\"\/wp-content\/uploads\/2022\/09\/wxsync-2022-09-10726fb8b19ce81840e29df185fcf1a3.png\"  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;margin-bottom: 0px;line-height: 1.5em;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe3. \u86cb\u767d\u8d28\u7684\u6c28\u57fa\u9178\u5e8f\u5217\uff08HP\u6a21\u578b\uff09\u51b3\u5b9a\u4e86\u5176\u6298\u53e0\u6001\u7684\u6c28\u57fa\u9178\u6b8b\u57fa\u63a5\u89e6\u7f51\u7edc\u3002\u5de6\u56fe\u4e2d\u7684H\u4e0eP\u5206\u522b\u4ee3\u8868\u758f\u6c34\u548c\u4eb2\u6c34\uff08\u6781\u6027\uff09\u6b8b\u57fa\uff0c\u53f3\u56fe\u8282\u70b9\u4e2d\u5fc3\u7684\u6570\u5b57\u4ee3\u8868\u5176\u5ea6\u6570\uff08\u8fd1\u90bb\u6570\uff09\uff0c\u53f3\u56fe\u4e2d\u6b8b\u57fa\u63a5\u89e6\u7f51\u7edc\u8868\u73b0\u51fa\u8f83\u9ad8\u7684\u540c\u914d\u6027\u3002<\/span><\/section>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5728\u4e00\u4e2a\u590d\u6742\u7f51\u7edc\u4e0a\uff0c\u5982\u679c\u90a3\u4e9b\u5ea6\u6570<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u8fde\u8fb9\u6570\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8f83\u5927\u7684\u8282\u70b9\u503e\u5411\u4e8e\u8ddf\u5ea6\u6570\u540c\u6837\u8f83\u5927\u7684\u8282\u70b9\u76f8\u8fde\u63a5\uff0c\u90a3\u4e48\u8fd9\u6837\u7684\u7f51\u7edc\u5c31\u662f\u540c\u914d\u7684\u3002\u4e3e\u4e2a\u4f8b\u5b50\uff0c\u5047\u5982\u5728\u4e00\u4e2a\u793e\u4ea4\u7f51\u7edc\u4e0a\uff0c\u5404\u79cd\u5927V\u7528\u6237\u62b1\u56e2\u53d6\u6696\uff0c\u76f8\u4e92\u5173\u6ce8\uff0c\u800c\u5404\u79cd\u666e\u901a\u7528\u6237\u53ea\u80fd\u8ddf\u81ea\u5df1\u540c\u6837\u662f\u666e\u901a\u7528\u6237\u7684\u4e09\u4e94\u597d\u53cb\u76f8\u4e92\u5173\u6ce8\uff0c\u8fd9\u6837\u7684\u7f51\u7edc\u5c31\u662f\u540c\u914d\u7684\u3002\u53cd\u4e4b\uff0c\u5982\u679c\u5ea6\u6570\u8f83\u5927\u7684\u8282\u70b9\u503e\u5411\u4e8e\u8ddf\u5ea6\u6570\u8f83\u5c0f\u7684\u8282\u70b9\u8fde\u63a5\uff0c\u4f8b\u5982\u5728\u4e00\u4e2a\u793e\u4ea4\u7f51\u7edc\u4e0a\uff0c\u4e00\u4e2a\u5927V\u53ef\u80fd\u5438\u5f15\u5230\u8bb8\u591a\u4f4e\u5173\u6ce8\u6570\u7684\u666e\u901a\u7528\u6237\u5173\u6ce8\uff0c\u8fd9\u6837\u7684\u7f51\u7edc\u5c31\u4e0d\u662f\u540c\u914d\u7684\u3002\u86cb\u767d\u8d28\u7684\u6b8b\u57fa\u63a5\u89e6\u7f51\u7edc\u662f\u9ad8\u5ea6\u540c\u914d\u7684\uff0c\u8fd9\u662f\u56e0\u4e3a\u6784\u6210\u86cb\u767d\u8d28\u7684\u6c28\u57fa\u9178\u6b8b\u57fa\u53ef\u4ee5\u88ab\u5206\u4e3a\u201c\u4eb2\u6c34\u201d\u548c\u201c\u758f\u6c34\u201d\u4e24\u7c7b\uff0c\u758f\u6c34\u6c28\u57fa\u9178\u6b8b\u57fa\u5f80\u5f80\u88ab\u5305\u57cb\u5728\u86cb\u767d\u8d28\u7684\u5185\u90e8\uff0c\u5f62\u6210\u7d27\u5bc6\u7684\u5806\u79ef\uff0c\u800c\u4eb2\u6c34\u6c28\u57fa\u9178\u6b8b\u57fa\u5219\u66b4\u9732\u5728\u86cb\u767d\u8d28\u7684\u8868\u9762\uff0c\u751a\u81f3\u53ef\u80fd\u5f62\u6210\u9ad8\u5ea6\u67d4\u6027\u7684\u5377\u66f2<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u5982\u56fe3\u53f3\u6240\u793a\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5bf9AlphaFold\u9884\u6d4b\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u8fdb\u884c\u7edf\u8ba1\uff0c\u7814\u7a76\u8005\u4eec\u53d1\u73b0\uff0c\u751f\u7269\u4f53\u590d\u6742\u5ea6\u4e0e\u5176\u4f53\u5185\u86cb\u767d\u8d28\u7684\u6b8b\u57fa\u63a5\u89e6\u7f51\u7edc\u7684\u5e73\u5747\u540c\u914d\u6027\u6210\u6b63\u76f8\u5173\u5173\u7cfb\u3002\u8fd9\u4e00\u7ed3\u679c\u4e0e\u4e0a\u4e00\u8282\u8ba8\u8bba\u7684\u7edf\u8ba1\u8d8b\u52bf\u4e5f\u662f\u81ea\u6d3d\u7684\uff0c\u56e0\u4e3a\u540c\u914d\u6027\u7684\u6b8b\u57fa\u63a5\u89e6\u7f51\u7edc\u8ba9\u4eb2\u6c34\u548c\u758f\u6c34\u6c28\u57fa\u9178\u6b8b\u57fa\u5728\u7a7a\u95f4\u4e0a\u4ea7\u751f\u4e86\u5206\u9694\uff0c\u5bfc\u81f4\u201c\u8d2b\u8005\u8d8a\u8d2b\u201d\uff0c\u86cb\u767d\u8d28\u7ed3\u6784\u4e2d\u51fa\u73b0\u4e86\u66f4\u591a\u9ad8\u5ea6\u67d4\u6027\u7684\u65e0\u5e8f\u7247\u6bb5\uff0c\u86cb\u767d\u8d28\u7684\u56de\u8f6c\u534a\u5f84\u4e5f\u56e0\u6b64\u589e\u52a0\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5728\u89c2\u5bdf\u5230\u86cb\u767d\u8d28\u6b8b\u57fa\u63a5\u89e6\u7f51\u7edc\u7684\u62d3\u6251\u6027\u8d28\u5728\u8fdb\u5316\u4e2d\u51fa\u73b0\u7684\u7edf\u8ba1\u8d8b\u52bf\u4e4b\u540e\uff0c\u7814\u7a76\u8005\u4eec\u53c8\u8fdb\u4e00\u6b65\u5bf9\u86cb\u767d\u8d28\u7684\u5e8f\u5217\u8fdb\u884c\u4e86\u7edf\u8ba1\u3002\u5982\u56fe3\u6240\u793a\uff0c\u86cb\u767d\u8d28\u7684\u4e09\u7ef4\u7ed3\u6784\u7531\u5176\u5e8f\u5217\u6240\u51b3\u5b9a\uff0c\u90a3\u4e48\uff0c\u5230\u5e95\u662f\u5e8f\u5217\u4e0a\u7684\u4ec0\u4e48\u7279\u5f81\u5bfc\u81f4\u4e86\u86cb\u767d\u8d28\u6b8b\u57fa\u63a5\u89e6\u7f51\u7edc\u7684\u540c\u914d\u6027\u5462\uff1f\u7814\u7a76\u8005\u4eec\u53d1\u73b0\uff0c\u4eb2\u6c34\u548c\u758f\u6c34\u6c28\u57fa\u9178\u6b8b\u57fa\u5728\u4e09\u7ef4\u7a7a\u95f4\u4e2d\u7684\u5206\u9694\uff0c\u4e0e\u5176\u5728\u5e8f\u5217\u4e0a\u7684\u5206\u9694\u662f\u76f8\u5173\u7684\u3002\u6362\u8a00\u4e4b\uff0c\u5982\u679c\u4e00\u4e2a\u86cb\u767d\u8d28\u7684\u5e8f\u5217\u51fa\u73b0\u4e86\u5927\u6bb5\u7684\u8fde\u7eed\u4eb2\u6c34\u6216\u8005\u8fde\u7eed\u758f\u6c34\u6c28\u57fa\u9178\uff0c\u8fd9\u6837\u7684\u5e8f\u5217\u5c06\u66f4\u5bb9\u6613\u5f62\u6210\u9ad8\u5ea6\u540c\u914d\u7684\u6b8b\u57fa\u63a5\u89e6\u7f51\u7edc\u3002\u7814\u7a76\u8005\u4eec\u89c2\u5bdf\u5230\uff0c\u968f\u7740\u7269\u79cd\u590d\u6742\u5ea6\u7684\u589e\u52a0\uff0c\u5e8f\u5217\u4e2d\u4eb2\u758f\u6c34\u6c28\u57fa\u9178\u7684\u5206\u9694\u7684\u786e\u6709\u9010\u6b65\u63d0\u5347\u7684\u8d8b\u52bf\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u9700\u8981\u7279\u522b\u5f3a\u8c03\u7684\u662f\uff0c\u4e0a\u8ff0\u7684\u5e8f\u5217\u5206\u6790\u5b8c\u5168\u4e0d\u4f9d\u8d56AlphaFold\u7684\u7ed3\u6784\u9884\u6d4b\uff0c\u800c\u4ece\u5e8f\u5217\u7ed3\u6784\u4e2d\u6240\u63ed\u793a\u7684\u7edf\u8ba1\u8d8b\u52bf\u53c8\u53ef\u4ee5\u5728\u5f88\u5927\u7a0b\u5ea6\u4e0a\u652f\u6301\u7ed3\u6784\u548c\u62d3\u6251\u5206\u6790\u7684\u7ed3\u679c\u3002\u8fd9\u4e9b\u7ed3\u679c\u8868\u660e\uff0c\u8bba\u6587\u6240\u8ba8\u8bba\u7684\u201c\u86cb\u767d\u8d28\u8fdb\u5316\u7684\u7edf\u8ba1\u8d8b\u52bf\u201d\u5e76\u975e\u662f\u7531\u7ed3\u6784\u9884\u6d4b\u65b9\u6cd5\u6240\u5e26\u6765\u7684\u7cfb\u7edf\u504f\u5dee\uff0c\u800c\u662f\u7684\u786e\u53cd\u6620\u4e86\u67d0\u79cd\u81ea\u7136\u8d8b\u52bf\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<h3 style=\"margin-bottom: 0em;outline: 0px;color: rgb(34, 34, 34);letter-spacing: 0.544px;white-space: normal;font-family: mp-quote, -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;letter-spacing: 0.544px;text-align: right;font-size: 13px;visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;outline: 0px;letter-spacing: 0.544px;text-align: center;visibility: visible;\">\n<section style=\"outline: 0px;display: inline-block;vertical-align: middle;visibility: visible;\">\n<section style=\"margin-bottom: -2px;outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;visibility: visible;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;clear: both;line-height: 0;visibility: visible;\">\n<section style=\"outline: 0px;line-height: 0;width: 0px;visibility: visible;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align: top;visibility: visible;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 10px;padding-left: 10px;outline: 0px;border-left: 3px solid rgb(33, 166, 210);border-right: 3px solid rgb(33, 166, 210);border-top-color: rgb(33, 166, 210);border-bottom-color: rgb(33, 166, 210);font-size: 16px;color: rgb(0, 0, 0);line-height: 1.4;visibility: visible;\">\n<p style=\"outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;text-align: left;color: rgb(33, 166, 210);letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;caret-color: rgb(89, 89, 89);visibility: visible;\">5. \u529f\u80fd\u4e13\u4e00\u6027<\/span><\/strong><\/strong><\/p>\n<\/section>\n<section style=\"margin-top: -2px;outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;visibility: visible;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u86cb\u767d\u8d28\u7684\u751f\u7269\u529f\u80fd\u662f\u7531\u5176\u7ed3\u6784\u6240\u51b3\u5b9a\u7684\u3002\u4e0a\u6587\u6240\u8ba8\u8bba\u7684\u5e8f\u5217\u3001\u62d3\u6251\u548c\u7ed3\u6784\u53d8\u5316\u6beb\u65e0\u7591\u95ee\u4f1a\u5f71\u54cd\u86cb\u767d\u8d28\u7684\u751f\u7269\u529f\u80fd\u3002\u90a3\u4e48\uff0c\u86cb\u767d\u8d28\u7684\u751f\u7269\u529f\u80fd\u4f1a\u968f\u7740\u7269\u79cd\u590d\u6742\u5ea6\u7684\u63d0\u5347\uff0c\u4ea7\u751f\u600e\u6837\u7684\u7edf\u8ba1\u8d8b\u52bf\u5462\uff1f<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u4e3a\u4e86\u7814\u7a76\u8fd9\u4e00\u95ee\u9898\uff0c\u7814\u7a76\u8005\u5bf9\u6b8b\u57fa\u63a5\u89e6\u7f51\u7edc\u7684\u62c9\u666e\u62c9\u65af\u77e9\u9635<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08graph Laplcaian\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8fdb\u884c\u4e86\u8c31\u5206\u6790\uff0c\u8fd9\u79cd\u5206\u6790\u65b9\u6cd5\u5176\u5b9e\u5c31\u662f\u57fa\u4e8e\u5f39\u6027\u7f51\u7edc\u6a21\u578b\u7684\u7b80\u6b63\u6a21\u5206\u6790\u3002\u6211\u4eec\u66fe\u7ecf\u5728\u300a<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247521092&amp;idx=1&amp;sn=af3cffd50a2d5d0d9ed9ea0485ecbc05&amp;chksm=e897c9c9dfe040df61b91f9a9d3db64a8c6a6aea44b9be39905a2986c8ddf716ce9146f1537c&amp;scene=21#wechat_redirect\" textvalue=\"\u4e3a\u4ec0\u4e48\u86cb\u767d\u8d28\u517c\u5177\u53ef\u5851\u6027\u4e0e\u7a33\u5b9a\u6027\uff1f\u4ece\u8fdb\u5316\u89c6\u89d2\u63ed\u793a\u751f\u547d\u590d\u6742\u7cfb\u7edf\u7684\u5185\u5728\u5e73\u8861\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener noreferrer\">\u4e3a\u4ec0\u4e48\u86cb\u767d\u8d28\u517c\u5177\u53ef\u5851\u6027\u4e0e\u7a33\u5b9a\u6027\uff1f\u4ece\u8fdb\u5316\u89c6\u89d2\u63ed\u793a\u751f\u547d\u590d\u6742\u7cfb\u7edf\u7684\u5185\u5728\u5e73\u8861<\/a>\u300b\u8fd9\u7bc7\u6587\u7ae0\u4e2d\u4ecb\u7ecd\u8fc7\u76f8\u5173\u7684\u5206\u6790\u65b9\u6cd5\u3002\u7b80\u800c\u8a00\u4e4b\uff0c\u86cb\u767d\u8d28\u7684\u8fd0\u52a8\u53ef\u4ee5\u88ab\u7b80\u5316\u4e3a\u5176\u5728\u5929\u7136\u6001<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u80fd\u91cf\u6700\u4f4e\u7ed3\u6784\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u9644\u8fd1\u7684\u632f\u52a8\uff0c\u800c\u8fd9\u79cd\u632f\u52a8\u53ef\u4ee5\u7531\u4e00\u7cfb\u5217\u7684\u201c\u632f\u52a8\u6a21\u5f0f\u201d\u7684\u53e0\u52a0\u6765\u63cf\u8ff0\u3002\u62c9\u666e\u62c9\u65af\u77e9\u9635\u7684\u7279\u5f81\u503c<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08eigenvalue\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u6b63\u6bd4\u4e8e\u86cb\u767d\u8d28\u5206\u5b50\u632f\u52a8\u6a21\u5f0f\u7684\u9891\u7387\u7684\u5e73\u65b9\uff0c\u800c\u4e0e\u8fd9\u4e9b\u7279\u5f81\u503c\u76f8\u5bf9\u5e94\u7684\u7279\u5f81\u5411\u91cf<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08eigenvector\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5219\u63cf\u8ff0\u4e86\u76f8\u5e94\u632f\u52a8\u6a21\u5f0f\u7684\u57fa\u672c\u5f62\u6001<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u5404\u4e2a\u6c28\u57fa\u9178\u6b8b\u57fa\u4f1a\u671d\u7740\u600e\u6837\u7684\u65b9\u5411\u3001\u4ee5\u600e\u6837\u7684\u76f8\u5bf9\u632f\u5e45\u8fd0\u52a8\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002\u5728\u62c9\u666e\u62c9\u65af\u77e9\u9635\u7684\u7279\u5f81\u503c\u8c31\u4e2d\uff0c\u8d8a\u5c0f\u7684\u7279\u5f81\u503c\u53cd\u6620\u7684\u662f\u6c28\u57fa\u9178\u6b8b\u57fa\u66f4\u4e3a\u4f4e\u9891\u3001\u5927\u632f\u5e45\u7684\u96c6\u4f53\u8fd0\u52a8\uff0c\u800c\u8d8a\u5927\u7684\u7279\u5f81\u503c\u53cd\u6620\u7684\u5219\u662f\u9ad8\u9891\u3001\u5c0f\u632f\u5e45\u7684\u5c40\u57df\u8fd0\u52a8\u3002\u6216\u8005\u53cd\u8fc7\u6765\uff0c\u5982\u679c\u5173\u6ce8\u62c9\u666e\u62c9\u65af\u77e9\u9635\u7279\u5f81\u503c\u7684\u5012\u6570\uff0c\u5373\u62c9\u666e\u62c9\u65af\u77e9\u9635\u9006\u77e9\u9635\u4e2d\u8f83\u5927\u7684\u90a3\u4e9b\u7279\u5f81\u503c\uff0c\u8fd9\u5b9e\u9645\u4e0a\u7b49\u6548\u4e8e\u8fdb\u884c\u4e3b\u6210\u5206\u5206\u6790<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08principal component analysis, PCA\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002\u8fd9\u4e00\u65b9\u6cd5\u5e38\u5e38\u88ab\u7528\u4e8e\u5206\u6790\u86cb\u767d\u8d28\u5e73\u8861\u6001\u8fd0\u52a8\u4e2d\u7684\u201c\u4e3b\u6210\u5206\u201d\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;text-align: center;\"><img class=\"rich_pages wxw-img\" data-ratio=\"1.2970521541950113\"  data-type=\"png\" data-w=\"882\" style=\"height: auto !important;\" src=\"\/wp-content\/uploads\/2022\/09\/wxsync-2022-09-57c76dff8bfaded37de2516ed4a63bd5.png\"  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;margin-bottom: 0px;line-height: 1.5em;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe4. \u968f\u7740\u7269\u79cd\u590d\u6742\u5ea6\u7684\u63d0\u9ad8\uff0c\u751f\u7269\u4f53\u5185\u86cb\u767d\u8d28\u52a8\u529b\u5b66\u4e2d\u76f8\u5e94\u4e3b\u6210\u5206\u7684\u6bd4\u4f8b\u4f1a\u53d1\u751f\u53d8\u5316\uff0c\u86cb\u767d\u8d28\u7ed3\u6784\u53d8\u5316\u7684\u7a7a\u95f4\u4f1a\u51fa\u73b0\u201c\u964d\u7ef4\u201d\u7684\u8d8b\u52bf\u3002<\/span><\/section>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5bf9\u4e0d\u540c\u7269\u79cd\u4f53\u5185\u7684\u86cb\u767d\u8d28\u8fdb\u884c\u632f\u52a8\u8c31\u5206\u6790\uff0c\u7814\u7a76\u8005\u4eec\u53d1\u73b0\uff0c\u968f\u7740\u7269\u79cd\u590d\u6742\u5ea6\u7684\u63d0\u5347\uff0c\u86cb\u767d\u8d28\u5e73\u8861\u6001\u8fd0\u52a8\u4e2d\u7684\u4e3b\u6210\u5206\u6bd4\u4f8b\u4f1a\u53d1\u751f\u76f8\u5e94\u7684\u53d8\u5316\u3002\u4f8b\u5982\u540c\u6837\u94fe\u957f\u7684\u86cb\u767d\u8d28\uff0c\u5728\u5927\u80a0\u6746\u83cc\u4e2d\uff0c\u5b83\u8fd0\u52a8\u7684\u7b2c1\u4e3b\u6210\u5206\u8ddf\u7b2c2\u4e3b\u6210\u5206\u4e4b\u95f4\u7684\u76f8\u5bf9\u5927\u5c0f\u8f83\u4e3a\u63a5\u8fd1\uff0c\u800c\u5728\u4eba\u4f53\u4e2d\uff0c\u5b83\u7684\u7b2c1\u4e3b\u6210\u5206\u548c\u7b2c2\u4e3b\u6210\u5206\u4e4b\u95f4\u4f1a\u6709\u8f83\u5927\u7684\u533a\u522b<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u5982\u56fe4A\u6240\u793a\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002\u8fdb\u4e00\u6b65\u7684\u5206\u6790\u53d1\u73b0\uff0c\u968f\u7740\u7269\u79cd\u7531\u7b80\u5355\u5230\u590d\u6742\uff0c\u5176\u4f53\u5185\u7684\u86cb\u767d\u8d28\u5206\u5b50\u7684\u52a8\u529b\u5b66\u4f1a\u51fa\u73b0\u201c\u964d\u7ef4\u201d\u7684\u8d8b\u52bf\uff0c\u5373\u8fd0\u52a8\u7684\u7b2c1\u4e3b\u6210\u5206\u4f1a\u4e0e\u7b2c2\u4e3b\u6210\u5206\u4e4b\u95f4\u62c9\u5f00\u8d8a\u6765\u8d8a\u5927\u7684\u5dee\u8ddd\uff0c\u7b2c2\u4e3b\u6210\u5206\u4f1a\u8ddf\u7b2c3\u4e3b\u6210\u5206\u4e4b\u95f4\u62c9\u5f00\u8d8a\u6765\u8d8a\u5927\u7684\u5dee\u8ddd<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u56fe4B\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\uff0c\u4ee5\u6b64\u7c7b\u63a8\u3002\u8fd9\u79cd\u52a8\u529b\u5b66\u4e2d\u7684\u201c\u964d\u7ef4\u201d\u8d8b\u52bf\u8ba9\u86cb\u767d\u8d28\u7279\u5b9a\u7684\u529f\u80fd\u8fd0\u52a8\u6a21\u5f0f\u53d8\u5f97\u66f4\u52a0\u7a81\u51fa<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u5982\u56fe4C\u6240\u793a\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002\u5728\u590d\u6742\u5ea6\u66f4\u9ad8\u7684\u751f\u7269\u4f53\u5185\uff0c\u6709\u66f4\u591a\u86cb\u767d\u8d28\u503e\u5411\u4e8e\u6cbf\u7740\u7279\u5b9a\u7684\u4e3b\u6210\u5206\u65b9\u5411\u53d1\u751f\u529f\u80fd\u8fd0\u52a8\uff0c\u8fd9\u79cd\u7279\u5b9a\u7684\u4e3b\u6210\u5206\u65b9\u5411\u5f80\u5f80\u4e0e\u7279\u5b9a\u7684\u529f\u80fd\u6709\u5173\u3002\u7b80\u800c\u8a00\u4e4b\uff0c\u968f\u7740\u7269\u79cd\u4ece\u7b80\u5355\u5230\u590d\u6742\uff0c\u6784\u6210\u751f\u7269\u4f53\u7684\u86cb\u767d\u8d28\u5448\u73b0\u51fa\u4ece\u201c\u901a\u7528\u201d\u5230\u201c\u4e13\u7528\u201d\u7684\u7edf\u8ba1\u8d8b\u52bf\uff0c\u9ad8\u590d\u6742\u5ea6\u7684\u751f\u7269\u4f53\u5185\u66f4\u53ef\u80fd\u51fa\u73b0\u9ad8\u5ea6\u529f\u80fd\u4e13\u4e1a\u5316\u7684\u86cb\u767d\u8d28\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><strong><br  \/><\/strong><\/span><\/p>\n<h3 style=\"margin-bottom: 0em;outline: 0px;color: rgb(34, 34, 34);letter-spacing: 0.544px;white-space: normal;font-family: mp-quote, -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;letter-spacing: 0.544px;text-align: right;font-size: 13px;visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;outline: 0px;letter-spacing: 0.544px;text-align: center;visibility: visible;\">\n<section style=\"outline: 0px;display: inline-block;vertical-align: middle;visibility: visible;\">\n<section style=\"margin-bottom: -2px;outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;visibility: visible;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;clear: both;line-height: 0;visibility: visible;\">\n<section style=\"outline: 0px;line-height: 0;width: 0px;visibility: visible;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align: top;visibility: visible;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 10px;padding-left: 10px;outline: 0px;border-left: 3px solid rgb(33, 166, 210);border-right: 3px solid rgb(33, 166, 210);border-top-color: rgb(33, 166, 210);border-bottom-color: rgb(33, 166, 210);font-size: 16px;color: rgb(0, 0, 0);line-height: 1.4;visibility: visible;\">\n<p style=\"outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;text-align: left;color: rgb(33, 166, 210);letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;caret-color: rgb(89, 89, 89);visibility: visible;\">6. \u5ef6\u4f38\u8ba8\u8bba<\/span><\/strong><\/strong><\/p>\n<\/section>\n<section style=\"margin-top: -2px;outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;visibility: visible;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;text-align: justify;\"><\/span><br  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u86cb\u767d\u8d28\u7684\u201c\u529f\u80fd\u4e13\u4e1a\u5316\u201d\u548c\u751f\u7269\u4f53\u7684\u590d\u6742\u6027\u4e4b\u95f4\u7684\u7edf\u8ba1\u76f8\u5173\u6027\u4e0e\u6b64\u524d\u5927\u91cf\u751f\u7269\u5316\u5b66\u5b9e\u9a8c\u89c2\u5bdf\u7ed3\u679c\u4e00\u81f4\u3002\u8bb8\u591a\u7814\u7a76\u8868\u660e\uff0c\u7956\u5148\u9176\u5f80\u5f80\u5177\u6709\u66f4\u9ad8\u7684\u6df7\u6742\u6027<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08promiscuity\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\uff0c\u5373\u5b83\u4eec\u4e0d\u4ec5\u53ef\u4ee5\u50ac\u5316\u4e3b\u53cd\u5e94\uff0c\u8fd8\u5177\u6709\u50ac\u5316\u526f\u53cd\u5e94\u7684\u80fd\u529b\uff0c\u5229\u7528\u7956\u5148\u5e8f\u5217\u91cd\u5efa\u7684\u65b9\u6cd5\uff0c\u6709\u52a9\u4e8e\u8bbe\u8ba1\u5177\u6709\u9ad8\u70ed\u7a33\u5b9a\u6027\u548c\u9ad8\u6df7\u6742\u6027\u7684\u9176\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;text-align: center;\"><img class=\"rich_pages wxw-img\" data-ratio=\"0.6324417601380501\"  data-type=\"png\" data-w=\"1159\" style=\"height: auto !important;\" src=\"\/wp-content\/uploads\/2022\/09\/wxsync-2022-09-70b80dff8c5036a41aa52ce1c028ae4d.png\"  \/><\/p>\n<section style=\"margin-right: 8px;margin-left: 8px;margin-bottom: 0px;line-height: 1.5em;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe5. \u968f\u7740\u7269\u79cd\u7684\u590d\u6742\u5ea6\u63d0\u9ad8\uff0c\u5176\u4f53\u5185\u7684\u86cb\u767d\u8d28\u5206\u5b50\u6709\u67d0\u79cd\u4ece\u201c\u901a\u7528\u201d\u5411\u201c\u4e13\u4e00\u201d\u65b9\u5411\u8fdb\u5316\u7684\u7edf\u8ba1\u8d8b\u52bf\u3002\u8fd9\u79cd\u73b0\u8c61\u5e76\u4e0d\u662f\u751f\u7269\u4f53\u7cfb\u7684\u67d0\u79cd\u7279\u4f8b\uff0c\u800c\u662f\u590d\u6742\u7cfb\u7edf\u4e2d\u5177\u6709\u666e\u9002\u6027\u7684\u67d0\u79cd\u8bbe\u8ba1\u539f\u5219\u3002<\/span><\/section>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u7956\u5148\u9176\u7684\u70ed\u7a33\u5b9a\u6027\u548c\u9ad8\u6df7\u6742\u6027\u4e0e\u7956\u5148\u7269\u79cd\u7684\u4f4e\u590d\u6742\u6027\u662f\u76f8\u5339\u914d\u7684\u3002\u590d\u6742\u6027\u4f4e\u7684\u751f\u7269\u4f53\u7684\u57fa\u56e0\u7ec4\u76f8\u5bf9\u8f83\u5c0f\uff0c\u5176\u4f53\u5185\u6240\u5305\u542b\u7684\u9176\u7684\u79cd\u7c7b\u4e5f\u8f83\u5c11\u3002\u5c3d\u7ba1\u57fa\u56e0\u7ec4\u89c4\u6a21\u5c0f\uff0c\u4f46\u9ad8\u6df7\u6742\u6027\u7684\u9176\u53ef\u4ee5\u5e2e\u52a9\u8fd9\u4e9b\u751f\u7269\u4f53\u5b9e\u73b0\u5404\u79cd\u751f\u547d\u6d3b\u52a8\u3002\u76f8\u53cd\uff0c\u8f83\u5927\u7684\u57fa\u56e0\u7ec4\u53ef\u4ee5\u7f16\u7801\u66f4\u591a\u7684\u86cb\u767d\u8d28\uff0c\u80fd\u591f\u53d1\u6325\u9ad8\u5ea6\u4e13\u4e1a\u5316\u7684\u529f\u80fd\uff0c\u5e94\u5bf9\u66f4\u590d\u6742\u548c\u591a\u6837\u5316\u7684\u7ec6\u80de\u73af\u5883\u3002\u86cb\u767d\u8d28\u7684\u4e13\u4e1a\u5316\u548c\u591a\u6837\u5316\u4f7f\u5b83\u4eec\u80fd\u591f\u5728\u66f4\u590d\u6742\u548c\u591a\u6837\u5316\u7684\u7ec6\u80de\u73af\u5883\u4e2d\u53d1\u6325\u4f5c\u7528\u3002\u56e0\u6b64\uff0c\u590d\u6742\u7684\u751f\u7269\u4f53\u53ef\u4ee5\u66f4\u6709\u6548\u5730\u53d1\u6325\u5176\u751f\u7269\u529f\u80fd\uff0c\u83b7\u5f97\u9002\u5e94\u590d\u6742\u548c\u591a\u6837\u5316\u7684\u5916\u90e8\u73af\u5883\u7684\u53ef\u5851\u6027\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u751f\u7269\u4f53\u7684\u590d\u6742\u6027\u548c\u7ec4\u6210\u86cb\u767d\u8d28\u7684\u529f\u80fd\u4e13\u4e1a\u5316\u4e4b\u95f4\u7684\u517c\u5bb9\u6027\u4e0d\u662f\u751f\u7269\u4f53\u7cfb\u7684\u67d0\u79cd\u7279\u4f8b\uff0c\u800c\u662f\u590d\u6742\u7cfb\u7edf\u4e2d\u5177\u6709\u666e\u9002\u6027\u7684\u67d0\u79cd\u8bbe\u8ba1\u539f\u5219<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08design principle\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002\u590d\u6742\u7cfb\u7edf\u7684<strong>\u6574\u4f53<\/strong>\u548c<strong>\u90e8\u5206<\/strong>\u4e4b\u95f4\u662f\u76f8\u534f\u8c03\u7684\u3002\u5f53\u4e00\u4e2a\u7cfb\u7edf\u53d8\u5f97\u66f4\u52a0\u590d\u6742\u65f6\uff0c\u5176\u7ec4\u6210\u90e8\u5206\u6216\u5143\u7d20\u5e94\u8be5\u6539\u53d8\u5176\u5c5e\u6027<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u4f8b\u5982\u53d8\u5f97\u66f4\u52a0\u53ef\u5851\u6216\u6a21\u5757\u5316\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002\u4e00\u4e2a\u76f4\u89c2\u7684\u4f8b\u5b50\u5982\u56fe5\u6240\u793a\uff0c\u7528\u4e50\u9ad8\u73a9\u5177\u642d\u5efa\u4e0d\u540c\u590d\u6742\u5ea6\u7684\u5efa\u7b51\uff0c\u5982\u679c\u53ea\u9700\u8981\u642d\u5efa\u4e00\u4e2a\u7b80\u5355\u7684\u201c\u5efa\u7b51\u201d\uff0c\u53ea\u9700\u8981\u7528\u5f88\u5c11\u7684\u51e0\u79cd\u5143\u4ef6\u5c31\u80fd\u5b8c\u6210\uff0c\u6211\u4eec\u751a\u81f3\u53ef\u4ee5\u4ea4\u6362\u67d0\u4e9b\u5143\u4ef6\uff1b\u7136\u800c\u642d\u5efa\u4e00\u4e2a\u590d\u6742\u7684\u7ed3\u6784\u65f6\uff0c\u4e0d\u4ec5\u5143\u4ef6\u7684\u603b\u6570\u5927\u5927\u589e\u52a0\uff0c\u800c\u4e14\u5404\u79cd\u5143\u4ef6\u7684\u901a\u7528\u6027\u4e5f\u5728\u4e0d\u65ad\u964d\u4f4e<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u5373\u5728\u4e00\u4e2a\u4e50\u9ad8\u62fc\u56fe\u4e2d\uff0c\u4e24\u4e2a\u5f62\u72b6\u63a5\u8fd1\u7684\u5143\u4ef6\u5c31\u4e0d\u518d\u80fd\u4ea4\u6362\u4f7f\u7528\u4e86\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002\u5728\u7ecf\u6d4e\u751f\u6d3b\u4e2d\uff0c\u4e5f\u6709\u5f88\u591a\u7c7b\u4f3c\u7684\u73b0\u8c61\u3002\u4e00\u5bb6\u5de5\u5382\uff0c\u5982\u679c\u8d44\u91d1\u4e0d\u8db3\uff0c\u4f46\u4e34\u65f6\u53c8\u9700\u8981\u751f\u4ea7\u67d0\u79cd\u65b0\u4ea7\u54c1\uff0c\u5f80\u5f80\u4f1a\u5bf9\u539f\u6765\u7684\u751f\u4ea7\u7ebf\u8fdb\u884c\u6539\u88c5\u2014\u2014\u8fd9\u4e5f\u662f\u67d0\u79cd\u201c\u975e\u4e13\u4e00\u6027\u201d\u7684\u4f53\u73b0\uff1b\u5982\u679c\u8fd9\u5bb6\u5de5\u5382\u6709\u4e86\u5145\u8db3\u7684\u8d44\u91d1\uff0c\u5b83\u53ef\u4ee5\u6295\u8d44\u8d2d\u5165\u4e00\u6761\u5168\u65b0\u7684\u751f\u4ea7\u7ebf\uff0c\u4e13\u95e8\u751f\u4ea7\u65b0\u4ea7\u54c1\uff0c\u6b64\u65f6\uff0c\u867d\u7136\u6210\u672c\u6709\u6240\u63d0\u9ad8\uff0c\u4f46\u66f4\u4e3a\u4e13\u4e00\u7684\u751f\u4ea7\u7ebf\u751f\u4ea7\u6548\u7387\u5f80\u5f80\u4e5f\u4f1a\u66f4\u9ad8\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5f53\u7136\uff0c\u9700\u8981\u5f3a\u8c03\u7684\u662f\uff0c\u672c\u6587\u6240\u8ba8\u8bba\u7684\u5404\u79cd\u201c\u8d8b\u52bf\u201d\u90fd\u662f<strong>\u7edf\u8ba1\u6027\u7684<\/strong>\uff0c\u5b83\u6240\u53cd\u6620\u7684\u662f\u4e00\u79cd\u6574\u4f53\u8d8b\u52bf\uff0c\u800c\u4e0d\u662f\u67d0\u79cd\u653e\u4e4b\u56db\u6d77\u800c\u7686\u51c6\u7684\u6cd5\u5219<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u4f8b\u5982\uff0c\u4e5f\u53ef\u4ee5\u627e\u5230\u4e00\u4e9b\u9176\uff0c\u5b83\u4eec\u5177\u6709\u66f4\u9ad8\u7684\u67d4\u6027\uff0c\u540c\u65f6\u4e5f\u6709\u8f83\u9ad8\u7684\u6df7\u6742\u6027\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002\u603b\u4e4b\uff0c\u5177\u4f53\u5230\u6bcf\u4e00\u79cd\u86cb\u767d\u8d28\u5206\u5b50\uff0c\u5728\u5b9a\u5411\u8fdb\u5316\u548c\u8bbe\u8ba1\u7684\u8fc7\u7a0b\u4e2d\uff0c\u90fd\u9700\u8981\u5177\u4f53\u95ee\u9898\u5177\u4f53\u5206\u6790\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><strong><br  \/><\/strong><\/span><\/p>\n<h3 style=\"margin-bottom: 0em;outline: 0px;color: rgb(34, 34, 34);letter-spacing: 0.544px;white-space: normal;font-family: mp-quote, -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;letter-spacing: 0.544px;text-align: right;font-size: 13px;visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;outline: 0px;letter-spacing: 0.544px;text-align: center;visibility: visible;\">\n<section style=\"outline: 0px;display: inline-block;vertical-align: middle;visibility: visible;\">\n<section style=\"margin-bottom: -2px;outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;visibility: visible;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;clear: both;line-height: 0;visibility: visible;\">\n<section style=\"outline: 0px;line-height: 0;width: 0px;visibility: visible;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align: top;visibility: visible;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 10px;padding-left: 10px;outline: 0px;border-left: 3px solid rgb(33, 166, 210);border-right: 3px solid rgb(33, 166, 210);border-top-color: rgb(33, 166, 210);border-bottom-color: rgb(33, 166, 210);font-size: 16px;color: rgb(0, 0, 0);line-height: 1.4;visibility: visible;\">\n<p style=\"outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;text-align: left;color: rgb(33, 166, 210);letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;caret-color: rgb(89, 89, 89);visibility: visible;\">7. \u603b\u7ed3\u4e0e\u5c55\u671b<\/span><\/strong><\/strong><\/p>\n<\/section>\n<section style=\"margin-top: -2px;outline: 0px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;visibility: visible;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;visibility: visible;\"><br  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8fd9\u7bc7\u8bba\u6587\u5229\u7528\u5404\u79cd\u7edf\u8ba1\u7269\u7406\u65b9\u6cd5\u5bf9AlphaFoldDB\u8fdb\u884c\u4e86\u5168\u9762\u7684\u5206\u6790\uff0c\u5c55\u793a\u51fa\u86cb\u767d\u8d28\u8fdb\u5316\u4e2d\u7684\u7edf\u8ba1\u8d8b\u52bf\uff0c\u5373\uff1a\u968f\u7740\u751f\u7269\u4f53\u5411\u66f4\u9ad8\u7684\u590d\u6742\u6027\u8fdb\u5316\uff0c\u5176\u4f53\u5185\u7684\u86cb\u767d\u8d28<strong>\u5728\u7edf\u8ba1\u610f\u4e49\u4e0a<\/strong>\u503e\u5411\u4e8e\u5411\u66f4\u9ad8\u7684\u7075\u6d3b\u6027\u3001\u66f4\u9ad8\u7684\u7ed3\u6784\u591a\u6837\u6027\u8fdb\u5316\uff0c\u5206\u5b50\u672c\u8eab\u7684\u529f\u80fd\u4e13\u4e00\u6027\u4e5f\u5728\u4e0d\u65ad\u589e\u5f3a\u3002\u9664\u4e86\u5728\u8fd9\u7bc7\u6587\u7ae0\u4e2d\u6240\u8ba8\u8bba\u7684\u4e00\u4e9b\u5185\u5bb9\u4ee5\u5916\uff0c\u5728\u539f\u8bba\u6587\u4e2d\uff0c\u8fd8\u5bf9\u6b8b\u57fa\u63a5\u89e6\u7f51\u7edc\u7684\u6a21\u5757\u5ea6\u3001\u6b8b\u57fa\u5806\u79ef\u7684\u5206\u5f62\u7ef4\u5ea6\u3001\u8c31\u5206\u5e03\u7684Zipf\u6307\u6570\u7b49\u8fdb\u884c\u4e86\u5206\u6790\u3002\u672a\u6765\uff0c\u57fa\u4e8e\u4eba\u5de5\u667a\u80fd\u9884\u6d4b\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u7684\u86cb\u767d\u8d28\u7ec4\u5206\u6790\uff0c\u4e0e\u5176\u4ed6\u7c7b\u578b\u7684\u751f\u7269\u4fe1\u606f<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u5982\u86cb\u767d\u8d28\u4e0e\u86cb\u767d\u8d28\u7684\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\u3001\u86cb\u767d\u8d28\u7684\u8868\u8fbe\u6c34\u5e73\u3001\u8fdb\u5316\u901f\u5ea6\u7b49\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u76f8\u6574\u5408\uff0c\u5fc5\u5c06\u4e3a\u6211\u4eec\u63d0\u4f9b\u5bf9\u7ec6\u80de\u548c\u751f\u7269\u4f53\u7684\u884c\u4e3a\u548c\u8fdb\u5316\u63d0\u4f9b\u5168\u65b0\u7684\u89c1\u89e3\u3002<\/span><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(33, 166, 210);\"><strong>\u5ef6\u4f38\u9605\u8bfb<\/strong><\/span><\/p>\n<ul class=\"list-paddingleft-1\" style=\"list-style-type: disc;margin-left: 8px;margin-right: 8px;\">\n<li style=\"font-size: 15px;\">\n<p style=\"line-height: 1.75em;margin-left: 8px;margin-right: 8px;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247577069&amp;idx=1&amp;sn=a5cdd175134407980a250955bef59b30&amp;chksm=e896f760dfe17e760f551d154b64e71afeb503aa3251566ccfa1bf4237918446af461910f290&amp;scene=21#wechat_redirect\" textvalue=\"\u86cb\u767d\u8d28\u7684\u52a8\u529b\u5b66\u548c\u8fdb\u5316\u4e4b\u95f4\u7684\u5bf9\u5e94\u5173\u7cfb\uff1a\u4e24\u4e2a\u4e0d\u540c\u65f6\u95f4\u5c3a\u5ea6\u4e0b\u7684\u76f8\u540c\u6545\u4e8b\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener noreferrer\">\u86cb\u767d\u8d28\u7684\u52a8\u529b\u5b66\u548c\u8fdb\u5316\u4e4b\u95f4\u7684\u5bf9\u5e94\u5173\u7cfb\uff1a\u4e24\u4e2a\u4e0d\u540c\u65f6\u95f4\u5c3a\u5ea6\u4e0b\u7684\u76f8\u540c\u6545\u4e8b<\/a>&nbsp;<\/span><\/p>\n<\/li>\n<li style=\"font-size: 15px;\">\n<p style=\"line-height: 1.75em;margin-left: 8px;margin-right: 8px;margin-bottom: 8px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247521092&amp;idx=1&amp;sn=af3cffd50a2d5d0d9ed9ea0485ecbc05&amp;chksm=e897c9c9dfe040df61b91f9a9d3db64a8c6a6aea44b9be39905a2986c8ddf716ce9146f1537c&amp;scene=21#wechat_redirect\" textvalue=\"\u4e3a\u4ec0\u4e48\u86cb\u767d\u8d28\u517c\u5177\u53ef\u5851\u6027\u4e0e\u7a33\u5b9a\u6027\uff1f\u4ece\u8fdb\u5316\u89c6\u89d2\u63ed\u793a\u751f\u547d\u590d\u6742\u7cfb\u7edf\u7684\u5185\u5728\u5e73\u8861\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" style=\"font-size: 15px;\" data-linktype=\"2\" rel=\"noopener noreferrer\"><span style=\"font-size: 15px;\">\u4e3a\u4ec0\u4e48\u86cb\u767d\u8d28\u517c\u5177\u53ef\u5851\u6027\u4e0e\u7a33\u5b9a\u6027\uff1f\u4ece\u8fdb\u5316\u89c6\u89d2\u63ed\u793a\u751f\u547d\u590d\u6742\u7cfb\u7edf\u7684\u5185\u5728\u5e73\u8861<\/span><\/a><\/p>\n<\/li>\n<li style=\"font-size: 15px;\">\n<p style=\"line-height: 1.75em;margin-left: 8px;margin-right: 8px;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247635239&amp;idx=3&amp;sn=4c8d7392e476dbb52ed29b670ccdde34&amp;chksm=e8998baadfee02bc3defdba258eb431af5aedbca88f27478fb4a3d73cd4ace4035debd118ce8&amp;scene=21#wechat_redirect\" textvalue=\"\u535a\u58eb\u62db\u751f | \u9999\u6e2f\u6d78\u4f1a\u5927\u5b66\u7269\u7406\u7cfb\u7406\u8bba\u4e0e\u8ba1\u7b97\u7814\u7a76\u56e2\u961f\uff1a\u7edf\u8ba1\u7269\u7406\uff0c\u673a\u5668\u5b66\u4e60\uff0c\u8ba1\u7b97\u751f\u7269\u5b66\uff0c\u8111\u79d1\u5b66\u65b9\u5411\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener noreferrer\">\u535a\u58eb\u62db\u751f | \u9999\u6e2f\u6d78\u4f1a\u5927\u5b66\u7269\u7406\u7cfb\u7406\u8bba\u4e0e\u8ba1\u7b97\u7814\u7a76\u56e2\u961f\uff1a\u7edf\u8ba1\u7269\u7406\uff0c\u673a\u5668\u5b66\u4e60\uff0c\u8ba1\u7b97\u751f\u7269\u5b66\uff0c\u8111\u79d1\u5b66\u65b9\u5411<\/a>&nbsp;<\/span><\/p>\n<\/li>\n<\/ul>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><br  \/><\/p>\n<p style=\"margin-right: 8px;margin-left: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(33, 166, 210);\"><strong>\u53c2\u8003\u6587\u732e<\/strong><\/span><\/p>\n<section style=\"text-align: left;margin-left: 8px;margin-right: 8px;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">1. Senior AW, Evans R, Jumper J, Kirkpatrick J, Sifre L, Green T, Qin C, \u017d\u00eddek A, Nelson AWR, Bridgland A, et al. 2020. Improved protein structure prediction using potentials from deep learning.&nbsp;<em>Nature<\/em>&nbsp;577:706\u2013710.<\/span><\/section>\n<section style=\"text-align: left;margin-left: 8px;margin-right: 8px;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">2. Jumper J, Evans R, Pritzel A, Green T, Figurnov M, Ronneberger O, Tunyasuvunakool K, Bates R, \u017d\u00eddek A, Potapenko A, et al. 2021. Highly accurate protein structure prediction with AlphaFold.&nbsp;<em>Nature<\/em>&nbsp;596:583\u2013589.<\/span><\/section>\n<section style=\"text-align: left;margin-left: 8px;margin-right: 8px;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">3. Varadi M, Anyango S, Deshpande M, Nair S, Natassia C, Yordanova G, Yuan D, Stroe O, Wood G, Laydon A, et al. 2022. AlphaFold Protein Structure Database: Massively expanding the structural coverage of protein-sequence space with high-accuracy models.&nbsp;<em>Nucleic Acids Res<\/em>&nbsp;50:D439\u2013D444.<\/span><\/section>\n<section style=\"text-align: left;margin-left: 8px;margin-right: 8px;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">4. AlphaFold reveals the structure of the protein universe:&nbsp;https:\/\/www.deepmind.com\/blog\/alphafold-reveals-the-structure-of-the-protein-universe<\/span><\/section>\n<section style=\"text-align: left;margin-left: 8px;margin-right: 8px;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">5. Niklas KJ, Cobb ED, Dunker AK. 2014. The number of cell types, information content, and the evolution of complex multicellularity.&nbsp;<em>Acta Societatis Botanicorum Poloniae<\/em>&nbsp;83:337\u2013347.<\/span><\/section>\n<section style=\"margin: 0px 8px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;color: rgb(34, 34, 34);font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;font-weight: 400;letter-spacing: 0.544px;orphans: 2;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;background-color: rgb(255, 255, 255);line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin: 0px 8px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;line-height: 1.75em;\"><br  \/><\/section>\n<section powered-by=\"xiumi.us\" style=\"margin: 10px 0px 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);text-align: center;justify-content: center;\">\n<section style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;display: inline-block;width: auto;vertical-align: top;min-width: 10%;height: auto;box-shadow: rgb(0, 0, 0) 0px 0px 0px;border-bottom: 9px solid rgb(169, 215, 227);border-bottom-right-radius: 0px;\">\n<section powered-by=\"xiumi.us\" style=\"margin: 0px 0px -15px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin: 0px;padding: 0px 10px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;color: rgb(12, 130, 169);font-size: 16px;line-height: 2;letter-spacing: 3px;\">\n<p style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;clear: both;min-height: 1em;\"><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u590d\u6742\u79d1\u5b66\u6700\u65b0\u8bba\u6587<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);\">\n<p style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;color: rgb(63, 63, 63);font-family: PingFangSC-light;font-size: 15px;letter-spacing: 0.544px;\"  \/><\/p>\n<\/section>\n<section style=\"margin: 0px 8px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;clear: both;min-height: 1em;letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);line-height: 2em;\"><span style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;font-size: 15px;\">\u96c6\u667a\u6591\u56fe\u9876\u520a\u8bba\u6587\u901f\u9012\u680f\u76ee\u4e0a\u7ebf\u4ee5\u6765\uff0c\u6301\u7eed\u6536\u5f55\u6765\u81ea<span style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;font-style: italic;\">Nature\u3001Science<\/span>\u7b49\u9876\u520a\u7684\u6700\u65b0\u8bba\u6587\uff0c\u8ffd\u8e2a\u590d\u6742\u7cfb\u7edf\u3001\u7f51\u7edc\u79d1\u5b66\u3001\u8ba1\u7b97\u793e\u4f1a\u79d1\u5b66\u7b49\u9886\u57df\u7684\u524d\u6cbf\u8fdb\u5c55\u3002\u73b0\u5728\u6b63\u5f0f\u63a8\u51fa\u8ba2\u9605\u529f\u80fd\uff0c\u6bcf\u5468\u901a\u8fc7\u5fae\u4fe1\u670d\u52a1\u53f7\u300c\u96c6\u667a\u6591\u56fe\u300d\u63a8\u9001\u8bba\u6587\u4fe1\u606f\u3002\u626b\u63cf\u4e0b\u65b9\u4e8c\u7ef4\u7801\u5373\u53ef\u4e00\u952e\u8ba2\u9605\uff1a<\/span><br style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<p style=\"margin: 0px 8px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;clear: both;min-height: 1em;letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"margin: 0px 8px 0em;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;clear: both;min-height: 1em;font-family: -apple-system, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;background-color: rgb(255, 255, 255);text-align: center;\"><img class=\"rich_pages wxw-img\" data-backh=\"174\" data-backw=\"562\" data-fileid=\"100098022\" data-ratio=\"0.3088962108731466\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1214\" style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;vertical-align: bottom;width: 661px;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;height: auto !important;\" src=\"\/wp-content\/uploads\/2022\/09\/wxsync-2022-09-6d537ca5d0c35d3062bffcc6a7a23dcd.png\"  \/><\/p>\n<section style=\"margin: 0px 8px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;white-space: normal;\"><br style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;color: rgb(136, 136, 136);font-family: PingFangSC-light;font-size: 14px;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;font-weight: 400;letter-spacing: 1px;orphans: 2;text-align: justify;text-indent: 0px;text-transform: none;white-space: normal;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;background-color: rgb(255, 255, 255);text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;\"  \/><\/section>\n<section powered-by=\"xiumi.us\" style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);\">\n<p style=\"margin: 0px 8px 5px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;clear: both;min-height: 1em;\"><br  \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;background-color: rgb(255, 255, 255);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">\n<p style=\"margin: 0px 8px 5px;padding: 0px;clear: both;min-height: 1em;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;letter-spacing: 0.544px;color: rgb(0, 0, 0);font-size: 16px;text-align: center;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;text-align: left;color: rgb(33, 166, 210);font-family: PingFangSC-light;letter-spacing: 0.544px;\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;font-size: 15px;letter-spacing: 0.544px;\">\u63a8\u8350\u9605\u8bfb<\/span><\/strong><\/strong><\/p>\n<ul class=\"list-paddingleft-1\" style=\"margin: 0px 8px;padding: 0px 0px 0px 1.2em;box-sizing: border-box !important;width: 577.422px;max-width: 100%;overflow-wrap: break-word !important;outline: 0px;\">\n<li style=\"margin: 0px;padding: 0px;clear: both;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;font-weight: bold;\">\n<section style=\"margin: 0px 8px 10px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247521092&amp;idx=1&amp;sn=af3cffd50a2d5d0d9ed9ea0485ecbc05&amp;chksm=e897c9c9dfe040df61b91f9a9d3db64a8c6a6aea44b9be39905a2986c8ddf716ce9146f1537c&amp;scene=21#wechat_redirect\" textvalue=\"\u4e3a\u4ec0\u4e48\u86cb\u767d\u8d28\u517c\u5177\u53ef\u5851\u6027\u4e0e\u7a33\u5b9a\u6027\uff1f\u4ece\u8fdb\u5316\u89c6\u89d2\u63ed\u793a\u751f\u547d\u590d\u6742\u7cfb\u7edf\u7684\u5185\u5728\u5e73\u8861\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" style=\"text-decoration: underline;\" rel=\"noopener noreferrer\">\u4e3a\u4ec0\u4e48\u86cb\u767d\u8d28\u517c\u5177\u53ef\u5851\u6027\u4e0e\u7a33\u5b9a\u6027\uff1f\u4ece\u8fdb\u5316\u89c6\u89d2\u63ed\u793a\u751f\u547d\u590d\u6742\u7cfb\u7edf\u7684\u5185\u5728\u5e73\u8861<\/a><\/section>\n<\/li>\n<li style=\"margin: 0px;padding: 0px;clear: both;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;font-weight: bold;\">\n<section style=\"margin: 0px 8px 10px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247595120&amp;idx=4&amp;sn=3fa3b226272b45f5485bf774a384d746&amp;chksm=e8962efddfe1a7eb54c27b308f421a23e7b8789730cb87792032e24f3dd972079fa9bb0e80d9&amp;scene=21#wechat_redirect\" textvalue=\"\u7814\u7a76\u901f\u9012\uff1a\u6df1\u5ea6\u5b66\u4e60\u5f15\u5165\u9002\u5e94\u6027\uff0c\u63d0\u5347\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u80fd\u529b\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" style=\"text-decoration: underline;\" data-linktype=\"2\" rel=\"noopener noreferrer\">\u7814\u7a76\u901f\u9012\uff1a\u6df1\u5ea6\u5b66\u4e60\u5f15\u5165\u9002\u5e94\u6027\uff0c\u63d0\u5347\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u80fd\u529b<\/a><br  \/><\/section>\n<\/li>\n<li style=\"margin: 0px;padding: 0px;clear: both;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;font-weight: bold;\">\n<section style=\"margin: 0px 8px 10px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247577069&amp;idx=1&amp;sn=a5cdd175134407980a250955bef59b30&amp;chksm=e896f760dfe17e760f551d154b64e71afeb503aa3251566ccfa1bf4237918446af461910f290&amp;scene=21#wechat_redirect\" textvalue=\"\u86cb\u767d\u8d28\u7684\u52a8\u529b\u5b66\u548c\u8fdb\u5316\u4e4b\u95f4\u7684\u5bf9\u5e94\u5173\u7cfb\uff1a\u4e24\u4e2a\u4e0d\u540c\u65f6\u95f4\u5c3a\u5ea6\u4e0b\u7684\u76f8\u540c\u6545\u4e8b\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" style=\"text-decoration: underline;\" data-linktype=\"2\" rel=\"noopener noreferrer\">\u86cb\u767d\u8d28\u7684\u52a8\u529b\u5b66\u548c\u8fdb\u5316\u4e4b\u95f4\u7684\u5bf9\u5e94\u5173\u7cfb\uff1a\u4e24\u4e2a\u4e0d\u540c\u65f6\u95f4\u5c3a\u5ea6\u4e0b\u7684\u76f8\u540c\u6545\u4e8b<\/a><br  \/><\/section>\n<\/li>\n<li style=\"margin: 0px;padding: 0px;clear: both;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;font-weight: bold;\">\n<section style=\"margin: 0px 8px 10px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247576923&amp;idx=2&amp;sn=57f0d320812c01ff6f5ea97c09fc9623&amp;chksm=e896f7d6dfe17ec038e8d238dae313119fca8c62aabd4730896bc99398db981dd5d9d3e0b927&amp;scene=21#wechat_redirect\" textvalue=\"\u300a\u5f20\u6c5f\u00b7\u590d\u6742\u79d1\u5b66\u524d\u6cbf27\u8bb2\u300b\u5b8c\u6574\u4e0a\u7ebf\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" style=\"margin: 0px;padding: 0px;color: rgb(87, 107, 149);text-decoration: underline;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;\" rel=\"noopener noreferrer\">\u300a\u5f20\u6c5f\u00b7\u590d\u6742\u79d1\u5b66\u524d\u6cbf27\u8bb2\u300b\u5b8c\u6574\u4e0a\u7ebf\uff01<\/a><\/section>\n<\/li>\n<li style=\"margin: 0px;padding: 0px;clear: both;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;font-weight: bold;\">\n<section style=\"margin: 0px 8px 10px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247617062&amp;idx=1&amp;sn=e963acb6885ea3b26d32e91c12eae076&amp;chksm=e89650abdfe1d9bddf82c71e612a15bc4393d0a61cde39d325b01b3099247145c98b492c37b8&amp;scene=21#wechat_redirect\" textvalue=\"\u6210\u4e3a\u96c6\u667aVIP\uff0c\u89e3\u9501\u200d\u5168\u7ad9\u8bfe\u7a0b\uff0f\u8bfb\u4e66\u4f1a\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" style=\"margin: 0px;padding: 0px;color: rgb(87, 107, 149);text-decoration: none;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;\" rel=\"noopener noreferrer\"><span style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;letter-spacing: 0.544px;text-decoration: underline;\">\u6210\u4e3a\u96c6\u667aVIP\uff0c\u89e3\u9501\u5168\u7ad9\u8bfe\u7a0b\uff0f\u8bfb\u4e66\u4f1a<\/span><\/a><\/section>\n<\/li>\n<li style=\"margin: 0px;padding: 0px;clear: both;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;\">\n<section style=\"margin: 0px 8px 10px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247615893&amp;idx=2&amp;sn=96bad22819460c3b17f165fef8817c89&amp;chksm=e8965f18dfe1d60e531b3a749cfdfade06962791e3f1b100872d24e032b6b3130a6ead599060&amp;scene=21#wechat_redirect\" textvalue=\"\u52a0\u5165\u96c6\u667a\uff0c\u200d\u4e00\u8d77\u590d\u6742\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" style=\"margin: 0px;padding: 0px;color: rgb(87, 107, 149);text-decoration: underline;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;\" rel=\"noopener noreferrer\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;\">\u52a0\u5165\u96c6\u667a\uff0c\u4e00\u8d77\u590d\u6742\uff01<\/strong><strong style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;\"><\/strong><strong style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;\"><\/strong><strong style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;\"><\/strong><\/a><br style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;\"  \/><\/section>\n<\/li>\n<\/ul>\n<p style=\"margin: 0px 8px 5px;padding: 0px;clear: both;min-height: 1em;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;outline: 0px;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;\"  \/><\/p>\n<\/section>\n<section style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;\">\n<section style=\"margin: 0px;padding: 0px;max-width: 100%;overflow-wrap: break-word !important;box-sizing: border-box !important;\"><br  \/><\/section>\n<\/section>\n<section style=\"outline: currentcolor none 0px;letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;background-color: rgb(255, 255, 255);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;margin-bottom: 0px;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;font-size: 15px;text-align: left;color: rgb(255, 255, 255);font-family: PingFangSC-light;\"><span style=\"outline: 0px;background-color: rgb(12, 130, 169);\">\u70b9\u51fb\u201c\u9605\u8bfb\u539f\u6587\u201d\uff0c\u8df3\u8f6c\u8bba\u6587\u539f\u6587<strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;letter-spacing: 0.544px;orphans: 2;text-indent: 0px;text-transform: none;white-space: normal;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;font-size: 15px;text-align: left;color: rgb(255, 255, 255);font-family: PingFangSC-light;\"><span style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;background-color: rgb(12, 130, 169);\"><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;letter-spacing: 0.544px;orphans: 2;text-indent: 0px;text-transform: none;white-space: normal;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;font-size: 15px;text-align: left;color: rgb(255, 255, 255);font-family: PingFangSC-light;\"><span style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;background-color: rgb(12, 130, 169);\"><\/span><\/strong><\/span><\/strong><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;letter-spacing: 0.544px;orphans: 2;text-indent: 0px;text-transform: none;white-space: normal;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;font-size: 15px;text-align: left;color: rgb(255, 255, 255);font-family: PingFangSC-light;\"><\/strong><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;letter-spacing: 0.544px;orphans: 2;text-indent: 0px;text-transform: none;white-space: normal;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;font-size: 15px;text-align: left;color: rgb(255, 255, 255);font-family: PingFangSC-light;\"><\/strong><strong style=\"margin: 0px;padding: 0px;outline: 0px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;letter-spacing: 0.544px;orphans: 2;text-indent: 0px;text-transform: none;white-space: normal;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;font-size: 15px;text-align: left;color: rgb(255, 255, 255);font-family: PingFangSC-light;\"><\/strong><strong style=\"outline: 0px;letter-spacing: 0.544px;\"><\/strong><\/span><\/strong><\/section>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5bfc\u8bed \u7269\u79cd\u8fdb\u5316\u548c\u5206\u5b50\u8fdb\u5316\u662f\u8fdb\u5316\u751f\u7269\u5b66\u7814\u7a76\u7684\u4e24\u4e2a\u91cd\u8981\u4e3b\u9898\uff0c\u5b83\u4eec\u4e4b\u95f4\u662f\u5426\u5b58\u5728\u7740\u67d0\u79cd\u8054\u7cfb\uff1f\u8fd1\u65e5\uff0c\u65e5\u672c\u7406\u5316\u5b66\u7814\u7a76\u6240\u7814\u7a76\u79d1\u5b66\u5bb6\u3001\u96c6\u667a\u79d1\u5b66\u5bb6\u5510\u4e7e\u5143\u7b49\u4eba\uff0c\u5229\u7528\u4eba\u5de5\u667a\u80fd\u7cfb\u7edfAlphaFold\u9884\u6d4b\u7684\u86cb\u767d\u8d28\u7ed3\u6784\uff0c\u901a\u8fc7\u7edf\u8ba1\u7269\u7406\u5206\u6790\uff0c\u63ed\u793a\u51fa\u968f\u7740\u751f\u7269\u4f53\u590d\u6742\u5ea6\u7684\u63d0\u9ad8\uff0c\u751f\u7269\u4f53\u7684\u57fa\u672c\u7ec4\u6210\u5355\u5143\u2014\u2014\u86cb\u767d\u8d28\u5206\u5b50\u5728\u8fdb\u5316\u4e2d\u6240\u8868\u73b0\u51fa\u7684\u7edf\u8ba1\u8d8b\u52bf&#8230;<\/p>\n","protected":false},"author":1,"featured_media":37320,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"special":[],"_links":{"self":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/37332"}],"collection":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=37332"}],"version-history":[{"count":0,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/37332\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/media\/37320"}],"wp:attachment":[{"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=37332"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=37332"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=37332"},{"taxonomy":"special","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fspecial&post=37332"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}