{"id":43604,"date":"2023-07-08T13:25:14","date_gmt":"2023-07-08T05:25:14","guid":{"rendered":"https:\/\/swarma.org\/?p=43604"},"modified":"2023-07-08T13:25:14","modified_gmt":"2023-07-08T05:25:14","slug":"%e6%b7%b1%e5%ba%a6%e5%ad%a6%e4%b9%a0%e4%b8%8e%e5%88%86%e5%ad%90%e5%ad%a6%e4%b9%a0%e7%bb%93%e5%90%88%ef%bc%9a%e4%bb%8e%e6%8b%93%e6%89%91%e3%80%81%e5%87%a0%e4%bd%95%e5%92%8c%e6%96%87%e6%9c%ac%e8%a7%92","status":"publish","type":"post","link":"https:\/\/swarma.org\/?p=43604","title":{"rendered":"\u6df1\u5ea6\u5b66\u4e60\u4e0e\u5206\u5b50\u5b66\u4e60\u7ed3\u5408\uff1a\u4ece\u62d3\u6251\u3001\u51e0\u4f55\u548c\u6587\u672c\u89d2\u5ea6\u8fdb\u884c\u89e3\u6790"},"content":{"rendered":"<div class='wxsyncmain'>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 0px;outline: 0px;letter-spacing: 0.544px;white-space: normal;color: rgb(63, 63, 63);font-family: PingFangSC-light;font-size: 15px;background-color: rgb(255, 255, 255);visibility: visible;\" data-mpa-powered-by=\"yiban.io\">\n<section style=\"outline: 0px;display: inline-block;width: 661px;vertical-align: top;background-color: rgb(246, 246, 246);visibility: visible;\">\n<section style=\"outline: 0px;visibility: visible;\">\n<p style=\"text-align: center;\"><img class=\"rich_pages wxw-img js_insertlocalimg\" data-backh=\"374\" data-backw=\"578\" data-ratio=\"0.6472222222222223\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"width: 100%;height: auto !important;\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-d91633f1a70448bc2282d0e555d0b163.png\"  \/><\/p>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;outline: 0px;letter-spacing: 0.544px;visibility: visible;\">\n<section style=\"outline: 0px;width: 661px;visibility: visible;\">\n<section style=\"padding-right: 3px;outline: 0px;float: left;line-height: 1;visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;text-align: left;visibility: visible;\">\n<section style=\"padding-left: 10px;outline: 0px;display: inline-block;width: auto;vertical-align: top;min-width: 10%;height: auto;border-left: 3px solid rgb(33, 166, 210);border-bottom-left-radius: 0px;line-height: 0;visibility: visible;\">\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;transform: translate3d(-13px, 0px, 0px);visibility: visible;\">\n<section style=\"outline: 0px;display: inline-block;width: 25px;height: 10px;vertical-align: top;overflow: hidden;line-height: 0;border-style: solid solid none;border-width: 3px 3px 2px;border-radius: 0px;border-color: rgb(33, 166, 210) rgb(33, 166, 210) rgb(15, 76, 129);visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;transform: translate3d(-1px, 0px, 0px);visibility: visible;\">\n<section style=\"outline: 0px;text-align: justify;color: rgb(33, 166, 210);font-size: 16px;line-height: 1.5;visibility: visible;\">\n<p style=\"outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;visibility: visible;\">\u5bfc\u8bed<\/strong><\/p>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;transform: translate3d(-13px, 0px, 0px) rotateX(180deg);visibility: visible;\">\n<section style=\"outline: 0px;display: inline-block;width: 24px;height: 10px;vertical-align: top;overflow: hidden;line-height: 0;border-style: solid solid none;border-width: 3px 3px 2px;border-radius: 0px;border-color: rgb(33, 166, 210) rgb(33, 166, 210) rgb(15, 76, 129);visibility: visible;\"><br style=\"outline: 0px;visibility: visible;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 4px;padding-left: 4px;outline: 0px;clear: right;box-shadow: rgb(0, 0, 0) 0px 0px 0px;visibility: visible;min-height: 4.5em !important;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 5px;margin-bottom: 5px;outline: 0px;visibility: visible;\">\n<section style=\"padding-right: 8px;padding-left: 8px;outline: 0px;font-size: 13px;line-height: 2;letter-spacing: 0.544px;visibility: visible;\">\n<p style=\"outline: 0px;clear: none;line-height: 2em;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.578px;text-indent: 0em;font-size: 15px;visibility: visible;\"><span style=\"outline: 0px;font-size: 13px;letter-spacing: 0.544px;text-decoration-style: solid;text-decoration-color: rgb(63, 63, 63);visibility: visible;\">\u5728\u8ba1\u7b97\u751f\u7269\u3001\u5316\u5b66\u3001\u6750\u6599\u9886\u57df\uff0c\u4f34\u968f\u7740\u6df1\u5ea6\u5b66\u4e60\u7684\u5e7f\u6cdb\u4f7f\u7528\uff0c\u5206\u5b50\u8868\u5f81&nbsp; (representation) \u5df2\u7ecf\u6210\u4e3a\u6700\u57fa\u7840\u7684\u7814\u7a76\u95ee\u9898\u3002\u6765\u81ea\u52a0\u62ff\u5927 MILA 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style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;caret-color: var(--weui-BRAND);visibility: visible;\"><span style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"outline: 0px;color: rgb(0, 0, 0);text-align: start;visibility: visible;\">\u5173\u952e\u8bcd\uff1a\u6df1\u5ea6\u5b66\u4e60\uff0c\u5206\u5b50\u8868\u5f81\u5b66\u4e60\uff0c\u56fe\u795e\u7ecf\u7f51\u7edc\uff0c\u591a\u6a21\u6001\uff0c\u5206\u5b50\u7f16\u8f91\uff0c\u836f\u7269\u53d1\u73b0<\/strong><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/strong><\/strong><\/span><\/strong><\/span><\/strong><\/strong><\/strong><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;outline: 0px;visibility: visible;\">\n<section style=\"outline: 0px;width: 661px;visibility: visible;\">\n<section style=\"outline: 0px;clear: both;line-height: 0;visibility: visible;\">\n<section style=\"outline: 0px;line-height: 0;width: 0px;visibility: visible;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align: top;visibility: visible;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;outline: 0px;letter-spacing: 0.544px;white-space: normal;color: rgb(63, 63, 63);font-family: PingFangSC-light;font-size: 15px;background-color: rgb(255, 255, 255);text-align: center;visibility: visible;\">\n<section style=\"outline: 0px;vertical-align: middle;display: inline-block;line-height: 0;visibility: visible;\"><img class=\"rich_pages wxw-img\" data-fileid=\"100098753\" data-ratio=\"0.07314814814814814\"  data-type=\"png\" data-w=\"1080\" style=\"outline: 0px;vertical-align: middle;visibility: visible !important;width: 677px !important;height: auto !important;\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-6f9f672988af7db277f019eec3e6e952.png\"  \/><strong style=\"outline: 0px;font-size: 13px;letter-spacing: 0.544px;text-align: right;color: rgb(0, 0, 0);visibility: visible;\"><\/strong><\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 0pt;margin-bottom: 0pt;outline: 0px;letter-spacing: 0.544px;white-space: normal;line-height: 1.7;font-family: PingFangSC-light;background-color: rgb(255, 255, 255);text-align: right;visibility: visible;\">\n<p style=\"outline: 0px;visibility: visible;\"><span style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;visibility: visible;color: rgb(73, 73, 73);font-size: 13px;letter-spacing: 0.544px;text-decoration-style: solid;text-decoration-color: rgb(73, 73, 73);\">\u5218\u5723\u8d85<\/span><span style=\"outline: 0px;color: rgb(0, 0, 0);font-size: 16px;font-weight: bold;letter-spacing: 0.544px;visibility: visible;\">&nbsp;<\/span><span style=\"outline: 0px;color: rgb(0, 0, 0);font-size: 13px;font-weight: bold;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"outline: 0px;visibility: visible;\">| \u4f5c\u8005<\/strong><\/span><\/span><\/p>\n<p style=\"outline: 0px;visibility: visible;\"><br  \/><\/p>\n<p style=\"outline: 0px;visibility: visible;\"><strong style=\"outline: 0px;color: rgb(0, 0, 0);font-size: 13px;letter-spacing: 0.544px;visibility: visible;\"><span style=\"outline: 0px;letter-spacing: 0.544px;visibility: visible;\"><strong style=\"outline: 0px;visibility: visible;\"><br  \/><\/strong><\/span><\/strong><\/p>\n<\/section>\n<section mpa-from-tpl=\"t\" style=\"margin-bottom: 0px;outline: 0px;color: rgb(34, 34, 34);letter-spacing: 0.544px;white-space: normal;font-family: -apple-system, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);visibility: visible;\">\n<section powered-by=\"xiumi.us\" mpa-from-tpl=\"t\" style=\"outline: 0px;visibility: visible;\">\n<section mpa-from-tpl=\"t\" style=\"outline: 0px;visibility: visible;\">\n<section mpa-from-tpl=\"t\" style=\"margin-right: 8px;margin-left: 8px;outline: 0px;letter-spacing: 0.544px;line-height: 1.75em;visibility: visible;\">\n<section style=\"margin-right: 8px;margin-left: 8px;outline: 0px;line-height: 1.75em;visibility: visible;\">\n<section style=\"outline: 0px;visibility: visible;\">\n<section data-id=\"85410\" data-tools=\"135\u7f16\u8f91\u5668\" style=\"outline: 0px;letter-spacing: 0.54px;visibility: visible;\">\n<section style=\"margin: 10px auto;outline: 0px;visibility: visible;\">\n<section style=\"margin-right: 3px;margin-left: 3px;padding: 20px;outline: 0px;box-shadow: rgb(227, 223, 223) 0px 0px 4px;background-color: rgb(254, 254, 254);visibility: visible;\">\n<section style=\"margin-right: 8px;margin-left: 8px;outline: 0px;text-align: left;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.54px;color: rgb(61, 170, 214);font-size: 16px;visibility: visible;\">\u76ee\u5f55<\/strong><\/section>\n<section style=\"margin-right: 8px;margin-left: 8px;outline: 0px;text-align: left;visibility: visible;\"><br style=\"outline: 0px;\"  \/><\/section>\n<section data-style=\"color: inherit; box-sizing: border-box;line-height: 1.75em; text-align: justify;\" style=\"outline: 0px;border-color: rgb(131, 13, 0);color: inherit;visibility: visible;\">\n<p style=\"margin-right: 8px;margin-bottom: 8px;margin-left: 8px;outline: 0px;line-height: 1.5em;visibility: visible;\"><strong style=\"outline: 0px;text-indent: 0em;letter-spacing: 0.54px;font-family: -apple-system, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><span style=\"outline: 0px;font-size: 15px;letter-spacing: 0.54px;text-decoration-style: solid;text-decoration-color: rgb(34, 34, 34);\">1&nbsp;\u7b80\u4ecb<\/span><\/strong><\/p>\n<h2 data-into-catalog-status=\"\" style=\"margin-right: 8px;margin-left: 8px;outline: 0px;font-family: system-ui, -apple-system, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;text-size-adjust: auto;line-height: 1.75em;text-align: left;\"><strong style=\"outline: 0px;\"><span style=\"outline: 0px;font-size: 15px;color: rgb(63, 63, 63);\">2 \u51e0\u4f55\u76f8\u5173\u7684<\/span><\/strong><strong style=\"font-family: system-ui, -apple-system, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;outline: 0px;\"><span style=\"outline: 0px;font-size: 15px;color: rgb(63, 63, 63);\">\u591a\u6a21\u6001\u4efb\u52a1<\/span><\/strong><span style=\"outline: 0px;font-size: 15px;color: rgb(63, 63, 63);\">\uff08Single-modal and Multi-modal Pretraining on Geometry\uff09<\/span><\/h2>\n<h2 data-into-catalog-status=\"\" style=\"margin-right: 8px;margin-left: 8px;outline: 0px;font-family: system-ui, -apple-system, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;text-size-adjust: auto;line-height: 1.75em;text-align: left;\"><strong style=\"outline: 0px;\"><span style=\"outline: 0px;font-size: 15px;color: rgb(63, 63, 63);\">3 \u6587\u672c\u63cf\u8ff0\u76f8\u5173\u7684\u591a\u6a21\u6001\u4efb\u52a1<\/span><\/strong><span style=\"outline: 0px;font-size: 15px;color: rgb(63, 63, 63);\">\uff08textual description modality enables more comprehensive tasks\uff09<\/span><\/h2>\n<h2 data-into-catalog-status=\"\" style=\"margin-right: 8px;margin-left: 8px;outline: 0px;font-family: system-ui, -apple-system, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;text-size-adjust: auto;line-height: 1.75em;\"><span style=\"outline: 0px;color: rgb(63, 63, 63);\"><strong style=\"outline: 0px;\"><span style=\"outline: 0px;font-size: 15px;\">4 \u603b\u7ed3<\/span><\/strong><\/span><strong style=\"font-size: 15px;color: inherit;letter-spacing: 0.54px;font-family: -apple-system, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;outline: 0px;\"><\/strong><\/h2>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;white-space: normal;text-align: center;line-height: 1.75em;\"><br style=\"outline: 0px;\"  \/><\/p>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;\"><span style=\"outline: 0px;font-size: 15px;color: rgb(63, 63, 63);\">&nbsp;<\/span><\/section>\n<h3 style=\"outline: 0px;letter-spacing: 0.544px;white-space: normal;color: rgb(34, 34, 34);font-family: -apple-system, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);\">\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;letter-spacing: 0.544px;font-family: PingFangSC-light;text-align: right;font-size: 13px;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;outline: 0px;letter-spacing: 0.544px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;text-align: center;\">\n<section style=\"outline: 0px;display: inline-block;vertical-align: middle;\">\n<section style=\"margin-bottom: -2px;outline: 0px;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<section style=\"outline: 0px;clear: both;line-height: 0;\">\n<section style=\"outline: 0px;line-height: 0;width: 0px;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 10px;padding-left: 10px;outline: 0px;border-left: 3px solid rgb(33, 166, 210);border-right: 3px solid rgb(33, 166, 210);border-top-color: rgb(33, 166, 210);border-bottom-color: rgb(33, 166, 210);font-size: 16px;color: rgb(0, 0, 0);line-height: 1.4;\">\n<p style=\"outline: 0px;\"><strong style=\"color: rgb(61, 170, 214);letter-spacing: 0.578px;\"><span style=\"font-size: 15px;\">1 \u7b80\u4ecb<\/span><\/strong><\/p>\n<\/section>\n<section style=\"margin-top: -2px;outline: 0px;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;color: rgb(34, 34, 34);background-color: rgb(255, 255, 255);line-height: 1.75em;\"><span style=\"outline: 0px;color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">&nbsp;<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5728\u8ba1\u7b97\u751f\u7269\u3001\u5316\u5b66\u3001\u6750\u6599\u9886\u57df\uff0c\u4f34\u968f\u7740\u6df1\u5ea6\u5b66\u4e60<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\"> (DL) <\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u7684\u5e7f\u6cdb\u4f7f\u7528\uff0c\u5206\u5b50\u7684\u8868\u5f81&nbsp; <\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">(representation) <\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5df2\u7ecf\u6210\u4e3a\u6700\u57fa\u7840\u7684\u7814\u7a76\u95ee\u9898\u3002\u4e00\u4e2a\u9c81\u68d2\u7684\u5206\u5b50\u8868\u5f81\uff0c\u80fd\u591f\u652f\u6491\u4e30\u5bcc\u7684\u4efb\u52a1\u3002\u6211\u4eec\u56e2\u961f\u4ece\u5c0f\u5206\u5b50\u8868\u5f81\u5f00\u59cb\u7814\u7a76\uff0c\u662f\u56e0\u4e3a\u5b83\u5305\u542b\u4e86\u975e\u5e38\u4e30\u5bcc\u7684\u591a\u6a21\u6001\u4fe1\u606f\uff0c\u5982\u4e0b\u56fe\u5c55\u793a\u7684\u516d\u4e2a\u6a21\u6001\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<p style=\"text-align: center;margin-bottom: 0px;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5425925925925926\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-5a889611b58869d03740f93803c94cc4.png\"  \/><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe1: \u5173\u4e8e\u5206\u5b50\u516d\u79cd\u6a21\u6001\u4e8b\u4f8b\u8bf4\u660e\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8fd9\u516d\u79cd\u6a21\u6001\u53c8\u53ef\u4ee5\u5206\u4e3a\u4e24\u5927\u7c7b\uff1a3D geometry\u30012D topology\u30011D String\u548c1D Fingerprint\u90fd\u662f\u5173\u4e8e\u5c0f\u5206\u5b50\u7684\u201c\u5185\u90e8\u201d\u5316\u5b66\u7ed3\u6784\u8868\u793a\uff1b\u800cbio KG\u548ctextual description\u5219\u66f4\u591a\u7684\u662f\u5173\u4e8e\u5206\u5b50\u7684\u201c\u5916\u90e8\u201d\u529f\u80fd\u63cf\u8ff0\u3002\u8fd9\u4e24\u5927\u7c7b\u7684\u6a21\u6001<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\"> (\u5373\u5185\u90e8\u548c\u5916\u90e8\u6a21\u6001)<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"> \u662f\u53ef\u4ee5\u76f8\u4e92\u8865\u5145\u4fe1\u606f\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u6b64\u5916\u8fd8\u9700\u8981\u5f3a\u8c03\u7684\u662f\uff0c\u5bf9\u4e8e\u5c0f\u5206\u5b50\u7684\u5185\u90e8\u6a21\u6001\uff0c2D topology\u548c1D String\u30011D Fingerprint\u5728\u4fe1\u606f\u5c42\u9762\u7b49\u4ef7\uff0c\u4e3b\u8981\u533a\u522b\u662f\u5173\u4e8e\u5206\u5b50\u56fe\u7684\u4e0d\u540c\u6570\u636e\u7ed3\u6784\u4ee5\u53ca\u5bf9\u5e94\u7684DL\u8868\u5f81\u3002\u4f46\u662f3D geometry\u548c2D topology\u5728\u4fe1\u606f\u5c42\u9762\u662f\u5f88\u5927\u7684\u533a\u522b\uff0c\u5e76\u4e14\u5b83\u4eec\u7684\u4fe1\u606f\u80fd\u591f\u4e92\u76f8\u8865\u5145\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u56f4\u7ed5\u4ee5\u4e0a\u4e24\u70b9\uff0c\u6211\u4eec\u5c06\u7b80\u5355\u4ecb\u7ecd\u56f4\u7ed5\u8fd9\u4e24\u79cd\u4fe1\u606f\u4e92\u4eab\uff0c\u4ecb\u7ecd\u4e24\u4e2a\u7cfb\u5217\u5de5\u4f5c\uff1a<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\"><strong><br  \/><\/strong><\/span><\/section>\n<ul class=\"list-paddingleft-1\" style=\"list-style-type: square;\">\n<li>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\"><strong>\u51e0\u4f55<\/strong>\uff08<strong>geometry\uff09\u76f8\u5173\u7684\u591a\u6a21\u6001\u4efb\u52a1<\/strong><\/span><\/section>\n<\/li>\n<\/ul>\n<p style=\"margin-bottom: 0px;line-height: 1.75em;text-align: left;margin-left: 16px;margin-right: 16px;\"><span style=\"color: rgb(63, 63, 63);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\"> \u2022&nbsp;GraphMVP:&nbsp;Pre-training Molecular Graph Representation with 3D Geometry, ICLR 2022<\/span><\/p>\n<p style=\"margin-bottom: 0px;line-height: 1.75em;text-align: left;margin-left: 16px;margin-right: 16px;\"><span style=\"color: rgb(63, 63, 63);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;GeoSSL:&nbsp;Molecular Geometry Pretraining with SE(3)-Invariant Denoising Distance Matching, ICLR 2023<\/span><\/p>\n<p style=\"margin-bottom: 0px;line-height: 1.75em;text-align: left;margin-left: 16px;margin-right: 16px;\"><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;font-size: 15px;color: rgb(63, 63, 63);\">&nbsp;\u2022&nbsp;MoleculeSDE:&nbsp;A Group Symmetric Stochastic Differential Equation Model for Molecule Multi-modal Pretraining, ICML 2023<\/span><\/p>\n<section style=\"line-height: 1.75em;text-align: left;margin-left: 16px;margin-right: 16px;margin-bottom: 16px;\"><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;font-size: 15px;color: rgb(63, 63, 63);\">&nbsp;\u2022&nbsp;Geom3D:&nbsp;Symmetry-Informed Geometric Representation for Molecules, Proteins, and Crystalline Materials, ArXiv 2023<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<ul class=\"list-paddingleft-1\" style=\"list-style-type: square;\">\n<li>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\"><strong>\u6587\u672c\u63cf\u8ff0\uff08<\/strong><strong>textual description\uff09\u76f8\u5173\u7684\u591a\u6a21\u6001\u4efb\u52a1<\/strong><\/span><\/section>\n<\/li>\n<\/ul>\n<p style=\"margin-bottom: 0px;line-height: 1.75em;text-align: left;margin-left: 16px;margin-right: 16px;\"><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;font-size: 15px;color: rgb(63, 63, 63);\">&nbsp;\u2022&nbsp;GraphCG:&nbsp;Unsupervised Discovery of Steerable Factors in Graphs, NeurIPS Workshop 2022<\/span><\/p>\n<p style=\"margin-bottom: 0px;line-height: 1.75em;text-align: left;margin-left: 16px;margin-right: 16px;\"><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;font-size: 15px;color: rgb(63, 63, 63);\">&nbsp;\u2022&nbsp;MoleculeSTM:&nbsp;Multi-modal Molecule Structure-text Model for Text-based Editing and Retrieval, ArXiv 2022<\/span><\/p>\n<p style=\"margin-bottom: 0px;line-height: 1.75em;text-align: left;margin-left: 16px;margin-right: 16px;\"><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;font-size: 15px;color: rgb(63, 63, 63);\">&nbsp;\u2022&nbsp;ProteinDT:&nbsp;A Text-guided Protein Design Framework, ArXiv 2023<\/span><\/p>\n<p style=\"margin-bottom: 0px;line-height: 1.75em;text-align: left;margin-left: 16px;margin-right: 16px;\"><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;font-size: 15px;color: rgb(63, 63, 63);\">&nbsp;\u2022&nbsp;ChatDrug:&nbsp;ChatGPT-powered Conversational Drug Editing Using Retrieval and Domain Feedback, ArXiv 2023<\/span><\/p>\n<ul class=\"list-paddingleft-1\" style=\"margin-left: 8px;margin-right: 8px;\">\n<section style=\"margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<\/ul>\n<h2 data-into-catalog-status=\"\" style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;background-color: rgb(255, 255, 255);font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;\">&nbsp;<\/span><br  \/><\/h2>\n<h3 style=\"outline: 0px;letter-spacing: 0.544px;white-space: normal;color: rgb(34, 34, 34);font-family: -apple-system, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);\">\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;letter-spacing: 0.544px;font-family: PingFangSC-light;text-align: right;font-size: 13px;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;outline: 0px;letter-spacing: 0.544px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;text-align: center;\">\n<section style=\"outline: 0px;display: inline-block;vertical-align: middle;\">\n<section style=\"margin-bottom: -2px;outline: 0px;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<section style=\"outline: 0px;clear: both;line-height: 0;\">\n<section style=\"outline: 0px;line-height: 0;width: 0px;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 10px;padding-left: 10px;outline: 0px;border-left: 3px solid rgb(33, 166, 210);border-right: 3px solid rgb(33, 166, 210);border-top-color: rgb(33, 166, 210);border-bottom-color: rgb(33, 166, 210);font-size: 16px;color: rgb(0, 0, 0);line-height: 1.4;\">\n<p style=\"outline: 0px;\"><strong style=\"color: rgb(61, 170, 214);letter-spacing: 0.578px;\"><span style=\"font-size: 15px;\">2 Single-modal and Multi-modal Pretraining on Geometry<\/span><\/strong><\/p>\n<\/section>\n<section style=\"margin-top: -2px;outline: 0px;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;color: rgb(34, 34, 34);background-color: rgb(255, 255, 255);line-height: 1.75em;\"><span style=\"outline: 0px;color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">&nbsp;<\/span><\/section>\n<h3 data-into-catalog-status=\"\" style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(61, 170, 214);\"><strong><span style=\"font-size: 15px;\">2.1 Geom3D \u5206\u5b50\u7684\u51e0\u4f55\u8868\u5f81benchmark<\/span><\/strong><\/span><\/h3>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8be5\u7814\u7a76\u4ee5\u300aSymmetry-Informed Geometric Representation for Molecules, Proteins, and Crystalline Materials\u300b\u4e3a\u9898\uff0c\u53d1\u8868\u5728ArXiv\u4e0a\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.4856348470806302\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1079\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-baf70f6f74c4aeb453bd05cc9b69e029.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u4ece\u6570\u636e\u7ed3\u6784\u4e0a\uff0c\u5206\u5b50\u7684\u672c\u8d28<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u7a33\u5b9a\u6001\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u662f\u4e00\u4e2a\u7ed3\u6784\u7a33\u5b9a\u76843D\u70b9\u4e91\u3002\u4ed6\u7684\u8868\u5f81\u4e3b\u8981\u6311\u6218\u5c31\u662f\u5982\u4f55\u4fdd\u8bc1\u5bf9\u4e8e\u65cb\u8f6c\u3001\u5e73\u79fb\u7b49\u53d8\u3002\u73b0\u6709\u7684\u5de5\u4f5c\u90fd\u662f\u5229\u7528\u4e86\u7fa4\u8868\u793a\u8bba\u6765\u8fdb\u884c\u63cf\u8ff0\uff0c\u800c\u6211\u4eec\u5728Geom3D\u8fd9\u4e2a\u5e73\u53f0\u4e2d\u5bf9\u4e8e\u73b0\u6709\u7684\u5de5\u4f5c\u8fdb\u884c\u4e86\u8fdb\u4e00\u6b65\u7684\u6574\u7406\u548c\u603b\u7ed3\u3002\u73b0\u6709\u7684\u51e0\u4f55\u5efa\u6a21<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08geometric modeling\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u53ef\u4ee5\u5927\u81f4\u5206\u4e3a\u5982\u4e0b\u4e09\u7c7b\uff1a<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.8327402135231317\" data-s=\"300,640\"  data-type=\"png\" data-w=\"843\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-04a5043c0e4e16b6386e8fc75a00cbbc.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe2: \u5173\u4e8esymmetry-informed\u7684\u51e0\u4f55\u8868\u5f81\u4e09\u79cd\u4e3b\u8981\u7c7b\u578b\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022 Invariant modeling\uff0c\u662f\u4ec5\u4ec5\u53ea\u8003\u8651\u4e86type-0 feature<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\"> (\u6bd4\u5982distance\u3001angle)<\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\u3002<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(63, 63, 63);font-size: 15px;letter-spacing: 0.034em;\">&nbsp;\u2022 Equivariant modeling\uff0c\u662f\u9664\u4e86type-0 feature\uff0c\u8fd8\u4f1a\u8003\u8651type-1 feature\uff0c\u8fd9\u5728\u6211\u4eec\u7684\u95ee\u9898\u4e2d\u5c31\u662f3D coordiante\u5750\u6807\u3002\u800c\u4e3a\u4e86\u4fdd\u8bc1modeling\u5bf9\u4e8eSE(3)\u7684\u7b49\u53d8\u6027\uff0c\u6709\u4e24\u79cd\u4e3b\u8981\u7684\u89e3\u51b3\u601d\u8def\uff1a<\/span><\/p>\n<p style=\"line-height: 1.75em;margin-left: 16px;margin-right: 16px;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022 Equivariant modeling with spherical frame basis \u662f\u628a\u76f8\u5bf9\u4f4d\u7f6e\u7684vector\u6295\u5f71\u5230spherical harmonics frame\u4e0a\u8fdb\u884c\u7684modeling\u3002\u5b83\u7684\u4f18\u52bf\u662f\u4e00\u79cd\u975e\u5e38\u6cdb\u5316\u7684\u6846\u67b6\uff0c\u6bd4\u5982\u53ef\u4ee5model\u66f4\u9ad8\u9636\u7684particle feature<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\"> (\u7269\u7406\u95ee\u9898\u4e2d\u4f7f\u7528\u66f4\u591a)<\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\uff1b\u800c\u7f3a\u70b9\u5219\u662f\u9700\u8981\u8fdb\u884ctensor product\uff0c\u8fd9\u4e2a\u8ba1\u7b97\u590d\u6742\u5ea6\u975e\u5e38\u9ad8\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;margin-left: 16px;margin-right: 16px;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022 Equivariant modeling with vector frame basis \u5219\u66f4\u52a0\u9488\u5bf93D coordinates\uff1a\u5b83\u662f\u628acoordinates\u6295\u5f71\u5230\u4e86\u4e00\u4e2avector frame\u4e0a\uff0c\u7136\u540e\u518d\u5bf9\u5176\u8fdb\u884cmodeling\u3002\u5b83\u7684\u4f18\u70b9\u662f\u6548\u7387\u6bd4\u8f83\u9ad8\uff0c\u4e0d\u9700\u8981\u8fdb\u884ctensor product\uff1b\u800c\u7f3a\u70b9\u5c31\u662f\u65e0\u6cd5\u5bf9\u9ad8\u9636\u7684\u7c92\u5b50\u8fdb\u884c\u5efa\u6a21\u3002<\/span><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u6b64\u5916\u6211\u4eec\u8fd8\u60f3\u63d0\u4e00\u4e0b\u5176\u4ed6\u7684\u5efa\u6a21\u65b9\u5f0f\uff0c\u6bd4\u5982\u5229\u7528\u7535\u5b50\u8f68\u9053\u7279\u5f81\u7684OrbNet\u6216\u8005\u5229\u7528\u674e\u7fa4\u5efa\u6a21\u7684LieTransformer\u3002<\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u57fa\u4e8e\u8fd9\u6837\u7684\u8bbe\u8ba1\u601d\u8def\uff0cGeom3D benchmark\u4e86\u5982\u4e0b\u6a21\u578b\uff1a<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;16\u4e2ageometric modeling\u6a21\u578b<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;14\u4e2ageometric pretraining\u6a21\u578b<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;46\u4e2a\u4e0d\u540cgeometric tasks\uff0c\u5305\u542b\u4e86\u5c0f\u5206\u5b50\u3001\u86cb\u767d\u8d28\u3001\u548c\u6750\u6599<\/span><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;font-size: 15px;color: rgb(63, 63, 63);\">&nbsp;\u2022&nbsp;\u6b64\u5916Geom3D\u8fd8\u5305\u542b\u4e867\u4e2a1D model\u548c11\u4e2a2D GNN model\u3002\u5173\u4e8e2D topology pretraining\uff0c\u6211\u4eec\u56e2\u961f\u4e5f\u6709\u4e00\u4e2a\u524d\u5e8f\u5de5\u4f5c\uff0cMolGraphEval\u3002\u611f\u5174\u8da3\u7684\u670b\u53cb\u6b22\u8fce\u67e5\u9605\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u4e0b\u9762\u6211\u4eec\u5c31\u91cd\u70b9\u4ecb\u7ecd\u5728\u5355\u4e00\u6a21\u6001\u548c\u591a\u6a21\u6001\u60c5\u51b5\u4e0b\uff0c\u5982\u4f55\u8fdb\u884c\u51e0\u4f55\u9884\u8bad\u7ec3<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08geometric pretraining\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<h3 data-into-catalog-status=\"\" style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: left;\"><span style=\"color: rgb(61, 170, 214);\"><strong><span style=\"font-size: 15px;\">2.2 GraphMVP &amp; MoleculeSDE: 2D-3D Pretraining<\/span><\/strong><\/span><\/h3>\n<section style=\"margin-bottom: 0px;\"><strong><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/strong><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><strong><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">2.2.1 GraphMVP\u7684\u7ed3\u6784\u5316\u6570\u636e\u9884\u8bad\u7ec3\u6846\u67b6\uff1a\u4ece\u6700\u5927\u5316\u4e92\u4fe1\u606f\u5230\u6761\u4ef6\u6982\u7387\u6c42\u548c<\/span><\/strong><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8be5\u7814\u7a76\u4ee5\u300aPre-training Molecular Graph Representation with 3D Geometry\u300b\u4e3a\u9898\uff0c\u53d1\u8868\u5728ICLR 2022\u4e0a\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-backh=\"213\" data-backw=\"578\" data-galleryid=\"\" data-ratio=\"0.36826347305389223\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1002\" style=\"width: 100%;height: auto;\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-0863416d9d27101ba1f12c5f9cb850c5.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5bf9\u4e8e\u5c0f\u5206\u5b50\u7684\u591a\u6a21\u6001\uff0c\u6211\u4eec\u6700\u5148\u8003\u8651\u5230\u7684\u5c31\u662f2D topology\u548c3D geometry\u3002\u540c\u65f6\u5bf9\u4e8e2D\u548c3D\u8fdb\u884c\u9884\u8bad\u7ec3\uff0c\u800c\u9884\u8bad\u7ec3\u7684\u601d\u8def\u975e\u5e38\u7b80\u5355\uff0c\u5c31\u662f\u6700\u5927\u53162D topology\u548c3D geometry\u4e4b\u95f4\u7684\u4e92\u4fe1\u606f<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\"> (MI)<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002\u4f46\u8fd9\u91cc\u6709\u4e00\u4e2a\u96be\u70b9\u5c31\u662f\u5982\u4f55\u5bf9\u4e8e\u7ed3\u6784\u5316\u6570\u636e\u8fdb\u884cMI\u8ba1\u7b97\uff0c\u800cGraphMVP\u6700\u5927\u7684\u8d21\u732e\u662f\u63d0\u51fa\u6765\u4e00\u4e2a\u5173\u4e8e\u6700\u5927\u5316MI\u7684\u4e00\u4e2a\u7b49\u4ef7\u5f62\u5f0f\uff1a<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<p style=\"text-align: center;margin-left: 8px;margin-right: 8px;margin-bottom: 0px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.07314814814814814\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"width: 425px;height: auto !important;\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-d627e51b5e44859aa5250753302a0a6c.png\"  \/><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><mo stretchy=\"false\"><\/mo><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><mo stretchy=\"false\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/mo><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8fd9\u5c31\u628aMI maximization\u95ee\u9898\u53d8\u6210\u4e86summation of two conditional log likelihoods<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\"> (\u516c\u5f0f1)<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\uff1b\u800c\u4e14\u4ed6\u5728\u8fd9\u91cc\u8fd8\u6709\u66f4\u5177\u4f53\u7684\u610f\u4e49\uff1a2D\u751f\u62103D\u7684\u6761\u4ef6\u6982\u7387 + 3D\u751f\u62102D\u7684\u6761\u4ef6\u6982\u7387\u3002\u8fd9\u4e2a\u5f62\u5f0f\u5bf9\u4e8e\u7ed3\u6784\u5316\u7684\u6570\u636e\u975e\u5e38\u53cb\u597d\uff0c\u56e0\u4e3a\u53ef\u4ee5\u5f15\u5165EBM\u8fd9\u79cd\u517c\u5177\u6cdb\u5316\u6027\u3001\u7075\u6d3b\u6027\u548c\u5f3a\u8868\u8fbe\u80fd\u529b\u7684\u6982\u7387\u6a21\u578b\u8fdb\u884c\u4f30\u8ba1\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8fd9\u91cc\u6211\u4eec\u5c06\u7ed3\u5408\u4e0b\u9762\u51e0\u4e2a\u5de5\u4f5c\u8fdb\u884c\u4e00\u4e9b\u5ef6\u5c55\u8865\u5145\u3002\u6ce8\uff1aGraphMVP\u7684\u63a8\u5bfc\u662f\u57fa\u4e8e\u79bb\u6563\u60c5\u51b5\uff0cGeoSSL\u8fd8\u63d0\u4f9b\u4e86\u8fde\u7eed\u7248\u672c\u7684\u63a8\u5bfc\uff0c\u4e14\u4e8c\u8005\u6700\u7ec8\u4f18\u5316\u76ee\u6807\u4e00\u6837\u3002\u611f\u5174\u8da3\u7684\u670b\u53cb\u53ef\u4ee5\u53c2\u8003\u6bd4\u5bf9\u4e24\u7bc7\u6587\u7ae0\u7684\u9644\u5f55\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u9996\u5148\u5bf9\u4e8e\u516c\u5f0f(1)\uff0c\u6211\u4eec\u53ef\u4ee5\u628a\u6761\u4ef6\u6982\u7387\u7528energy-based model<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\"> (EBM) <\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\u8fdb\u884c\u4f30\u8ba1\uff0c\u800cEBM\u672c\u8eab\u5c31\u6709\u975e\u5e38\u591a\u7684\u5bb6\u65cf\u65b9\u6cd5\u6765\u6c42\u89e3\uff0c\u6bd4\u5982noise contrastive estimation<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\"> (NCE)<\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\u3001score matching<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\"> (SM)<\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\u3001contrastive divergence\u3002<\/span><\/p>\n<section style=\"line-height: 1.75em;margin-left: 16px;margin-right: 16px;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022 GraphMVP\u5229\u7528NCE\u6c42\u89e3\uff0c\u6211\u4eec\u53eb\u505aEBM-NCE\u3002\u6211\u4eec\u53d1\u73b0EBM-NCE\u548cJensen-Shannon divergence\u8054\u7cfb\u5bc6\u5207\u3002\u4e8c\u8005\u7684\u76ee\u6807\u51fd\u6570\u4e00\u6837\uff0c\u53ea\u662f\u6c42\u89e3\u7684\u8fc7\u7a0b\u548c\u601d\u8def\u4e0d\u540c\u3002\u800cEBM-NCE\u548c\u5176\u4ed6contrastive self-supervised learning\u7684\u601d\u8def\u672c\u8d28\u90fd\u4e00\u6837\uff1a\u901a\u8fc7\u6784\u9020positive\u548cnegative pairs\uff0c\u7136\u540e\u589e\u5927positive pair\u7684similarity\uff0c\u5e76\u4e14\u89c1\u6548negative pair\u7684similarity\u3002<\/span><\/section>\n<section style=\"line-height: 1.75em;margin-left: 16px;margin-right: 16px;margin-bottom: 16px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u6b64\u5916EBM\u8fd8\u6709\u5176\u4ed6\u7684\u6c42\u89e3\u601d\u8def\uff0c\u6bd4\u5982score matching<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\"> (SM)<\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\uff0c\u6211\u4eec\u5f53\u65f6\u5728\u505aGraphMVP\u7684\u65f6\u5019\u5df2\u7ecf\u610f\u8bc6\u5230\u4e86\u5b83\u4e5f\u662fdo-able\u7684\u8def\uff0c\u4f46\u662f\u7b2c\u4e00\u7bc7\u5de5\u4f5c\u6765\u4e0d\u53ca\u8be6\u7ec6\u5c55\u5f00\u3002\u8fd9\u4e2a\u4e5f\u662f\u6307\u5bfc\u6211\u4eec\u540e\u9762\u505aGeoSSL\u548cMoleculeSDE\u7684\u65b9\u6cd5\u8bba\u3002<\/span><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u5176\u6b21\u5bf9\u4e8e\u516c\u5f0f(1)\uff0c\u6211\u4eec\u8fd8\u53ef\u4ee5\u5229\u7528\u53d8\u5206\u65b9\u6cd5\u6765\u4f30\u8ba1\u4e24\u4e2a\u6761\u4ef6\u6982\u7387\u7684evidence lower bound <\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\">(ELBO)<\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\u3002\u8fd9\u4e2a\u7c7b\u4f3cVAE\u548cDDPM\u3002<\/span><\/p>\n<section style=\"line-height: 1.75em;margin-left: 16px;margin-right: 16px;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022 GraphMVP\u5c31\u9996\u5148\u91c7\u7528\u4e86VAE\u7684\u5f62\u5f0f\uff0c\u63d0\u51fa\u4e86variation representation reconstruction<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\"> (VRR)<\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\u3002VRR\u662f\u5728representation space\u8fdb\u884creconstruction <\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\">(\u800c\u4e0d\u662fdata space)<\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\uff0c\u4ece\u800c\u6709\u4e86\u5bf9ELBO\u7684\u4f30\u8ba1\u3002\u5e76\u4e14\u6211\u4eec\u53d1\u73b0\uff0cnon-contrastive self-supervised learning<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\"> (\u6bd4\u5982BYOL\u3001SimSiam) <\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\u5c31\u662fVRR\u7684\u4e00\u79cd\u7279\u6b8a\u60c5\u51b5\u3002<\/span><\/section>\n<section style=\"line-height: 1.75em;margin-left: 16px;margin-right: 16px;margin-bottom: 16px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022 DDPM\u4e5f\u662f\u5728\u4f18\u5316ELBO\uff0c\u5e76\u4e14\u5b83\u548cdenoising score matching<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\"> (DSM) <\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\u662f\u975e\u5e38\u7c7b\u4f3c\u7684\u3002\u5b83\u4eec\u7684\u533a\u522b\u53ef\u4ee5\u901a\u8fc7Stochastic Differential Equation <\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\">(SDE)&nbsp;<\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\u4e00\u4e2a\u7edf\u4e00\u6846\u67b6\u4e0b\u7684\u4e24\u79cd\u53d8\u5f62\u4f53\u73b0\u3002\u8fd9\u4e00\u70b9\u6211\u4eec\u5728MoleculeSDE\u4e2d\u8fdb\u884c\u4e86\u66f4\u52a0\u8be6\u7ec6\u7684\u89e3\u91ca\u3002<\/span><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u6b64\u5916\uff0c\u5bf9\u4e8e\u8fd9\u51e0\u79cd\u601d\u8def\uff0c\u6211\u4eec\u8fd8\u53ef\u4ee5\u4ece\u53e6\u4e00\u4e2a\u89d2\u5ea6\u5c06\u8fd9\u4e9b\u65b9\u6cd5\u8fdb\u884c\u5206\u7c7b\u3002<\/span><\/p>\n<section style=\"line-height: 1.75em;margin-left: 16px;margin-right: 16px;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u7b2c\u4e00\u7c7b\u662fNCE<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\"> (\u5305\u542b\u4e86EBM-NCE\u3001InfoNCE\u3001GAN)<\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\uff0c\u56e0\u4e3a\u5b83\u4eec\u672c\u8d28\u601d\u8def\u5c31\u662f\u628a\u6982\u7387\u4f30\u8ba1\u95ee\u9898\u8f6c\u6362\u4e3a\u4e86\u5206\u7c7b\u95ee\u9898\uff0c\u4e5f\u5c31\u662fcontrastive learning\u3002\u5b83\u662f\u57fa\u4e8edata pair\u6765\u8fdb\u884cdistribution estimation\u3002<\/span><\/section>\n<p style=\"margin-bottom: 0px;line-height: 1.75em;margin-left: 16px;margin-right: 16px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u7b2c\u4e8c\u7c7b\u662f\u7c7b\u4f3cDSM\u3001VRR\uff0c\u76ee\u6807\u4efb\u52a1\u662f\u4e3a\u4e86\u91cd\u6784\u67d0\u4e00\u4e2adata\u6216\u8005data\u7684representation\u3002\u672c\u8d28\u662f\u628a\u6982\u7387\u4f30\u8ba1\u95ee\u9898\u8f6c\u6362\u4e3a\u4e86\u91cd\u6784\u95ee\u9898\uff0c\u4e5f\u5c31\u662fgenerative learning\u6216\u8005reconstruction learning\u3002\u5b83\u662f\u76f4\u63a5\u57fa\u4e8e\u6bcf\u4e00\u4e2a\u5355\u72ec\u7684data point\u6765\u8fdb\u884cdistribution estimation\u3002<\/span><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><strong><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">2.2.2 \u57fa\u4e8elatent space\u7684GraphMVP<\/span><\/strong><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.34807692307692306\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1040\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-61158bee1d96a02cdef389847c8a500e.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe3\uff1aGraphMVP\u7684\u6d41\u7a0b\u56fe\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5f53\u6211\u4eec\u6709\u4e86\u516c\u5f0f1\u5f15\u51fa\u7684\u4e00\u7cfb\u5217\u6c42\u89e3\u601d\u8def\u4e4b\u540e\u5c31\u975e\u5e38\u76f4\u63a5\u3002GraphMVP\u662f\u5b8c\u5168\u57fa\u4e8elatent space\uff0c\u4f7f\u7528\u4e86\u5982\u4e0b\u4e24\u4e2a\u76ee\u6807\u51fd\u6570\uff1a\u4e00\u4e2acontrastive loss\uff0c\u4e5f\u5c31\u662fEBM-NCE\uff1b\u4e00\u4e2agenerative loss\uff0c\u4e5f\u5c31\u662fVRR\u3002\u9664\u6b64\u4ee5\u5916\uff0cGraphMVP\u8fd8\u6709\u4e24\u4e2avariant\uff0cGraphMVP-C\u548cGraphMVP-G\uff0c\u5206\u522b\u8003\u8651\u5230\u4e86\u5982\u4f55\u52a0\u5165contrastive \u548c generative 2D SSL\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><strong><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">2.2.3 \u57fa\u4e8edata space\u7684MoleculeSDE<\/span><\/strong><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8be5\u7814\u7a76\u4ee5\u300aA Group Symmetric Stochastic Differential Equation Model for Molecule Multi-modal Pretraining\u300b\u4e3a\u9898\uff0c\u53d1\u8868\u5728ICML 2023\u4e0a\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.23579545454545456\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1056\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-5792459e42c85bcf1b9f11f707eabe18.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">MoleculeSDE\u662fGraphMVP\u7684follow-up\u5de5\u4f5c\u3002\u5728GraphMVP\u4e2d\u7684generative loss\uff0c\u6211\u4eec\u662f\u5229\u7528\u4e86VRR\u6765\u5bf9ELBO\u8fdb\u884c\u4f30\u8ba1\uff0c\u4f46\u662f\u8fd9\u79cd\u4f30\u8ba1\u4f1a\u9020\u6210\u4fe1\u606f\u635f\u5931\u3002\u8fd9\u91cc\u6211\u4eec\u63d0\u51fa\u4e86\u66f4\u52a0\u4e25\u683c\u7684\u6982\u7387\u4f30\u8ba1\uff0c\u4e5f\u5c31\u662f\u76f4\u63a5\u5728data space<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\"> (geometry\u548ctopology) <\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8fdb\u884c\u91cd\u6784\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u4f46\u8fd9\u91cc\u53c8\u6709\u4e00\u4e2a\u6311\u6218\uff0c\u5c31\u662f\u4ece2D\u52303D\u7684\u6761\u4ef6\u6982\u7387 <\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">(2D\u751f\u62103D) <\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u9700\u8981\u9075\u7167SE(3)\u7b49\u53d8\uff0c\u5373\u5bf9\u4e8e\u65cb\u8f6c\u3001\u5e73\u79fb\u7b49\u53d8\uff0c\u5e76\u4e14\u5bf9\u4e8e\u5bf9\u79f0\u53cd\u5bf9\u79f0\u3002\u4e3a\u4e86\u5b9e\u73b0\u8fd9\u4e2a\u76ee\u6807\uff0c\u6211\u4eec\u57fa\u4e8evector frame basis\u5f15\u5165\u4e86SE(3)-equivariant and reflection-antisymmetric SDE\u3002\u8fd9\u4e2a\u601d\u8def\u672c\u8d28\u4e0a\u662f\u5229\u7528score matching\u6216\u8005diffusion\u53bb\u6c42\u89e3\u516c\u5f0f1\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.3821892393320965\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1078\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-2851ae667713c30dc9e1eb4287710871.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe4\uff1aMoleculeSDE\u7684\u6d41\u7a0b\u56fe\u3002<\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u53e6\u5916\u6211\u4eec\u60f3\u5f3a\u8c03\u7684\u662f\uff0c\u5bf9\u4e8edownstream task\uff0c\u9664\u4e86\u5e38\u89c4\u76842D\u548c3D proeprty prediction\uff0cMoleculeSDE\u4e5f\u8ba9\u6211\u4eec\u6709\u4e86\u66f4\u591a\u6837\u5316\u7684\u9009\u62e9\u3002\u4e3b\u8981\u662f\u5bf9\u4e8e\u5c0f\u5206\u5b502D\u52303D\u7684\u751f\u6210\uff0c\u8fd9\u4e2atask\u7684\u610f\u4e49\u5e76\u4e0d\u4ec5\u4ec5\u5728\u4e8e\u80fd\u591f\u6709conformation generation\uff0c\u800c\u662f\u80fd\u591f\u6709\u57fa\u4e8e\u751f\u6210\u76843D coordinates \u8fdb\u4e00\u6b65\u8fdb\u884cmodeling\uff0c\u5982\u4e0b\u56fe5(3)\u6240\u793a\uff1a<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<p style=\"text-align: center;margin-bottom: 0px;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.54739336492891\" data-s=\"300,640\"  data-type=\"png\" data-w=\"844\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-c2cb8184957cfc769cf03fdd0747c89d.png\"  \/><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe5\uff1aMoleculeSDE\u7684\u4e09\u79cd\u4e0b\u6e38\u4efb\u52a1\u5c55\u793a\u3002<\/span><\/section>\n<\/figure>\n<h3 data-into-catalog-status=\"\" style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/h3>\n<h3 data-into-catalog-status=\"\" style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(61, 170, 214);\"><strong><span style=\"font-size: 15px;\">2.3 GeoSSL: 3D pretraining<\/span><\/strong><\/span><\/h3>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8be5\u7814\u7a76\u4ee5\u300aMolecular Geometry Pretraining with SE(3)-Invariant Denoising Distance Matching\u300b\u4e3a\u9898\uff0c\u53d1\u8868\u5728ICLR 2023\u4e0a\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.4316279069767442\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1075\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-86f08d45cd01f5eb9dd0a1668d172d9c.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">GraphMVP\u548cMoleculeSDE\u90fd\u662f\u8003\u8651\u6a21\u6001\u4e4b\u95f4\u7684\u9884\u8bad\u7ec3\u3002\u540c\u65f6\u6211\u4eec\u8fd8\u60f3\u5f3a\u8c03\u4ec5\u4ec5\u8003\u86513D geometry\u7684\u9884\u8bad\u7ec3\u3002\u8fd9\u4e2a\u5de5\u4f5c\u7684\u63a8\u51fa\u662f\u5728GraphMVP\u548cMoleculeSDE\u8fd9\u4e24\u4e2a\u5de5\u4f5c\u4e4b\u95f4\uff0c\u800c\u539f\u56e0\u5219\u662f\u56e0\u4e3a\u9884\u8bad\u7ec3\u7684\u6570\u636e\u96c6\u3002GraphMVP\u7684\u9884\u8bad\u7ec3\u662f\u5728GEOM\u6570\u636e\u4e0a<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u5f53\u65f6\u53d6\u4e86250K data\uff0c\u662f\u5df2\u77e5\u8f83\u5927\u7684\u5c0f\u5206\u5b503D\u6570\u636e\u96c6\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002\u800c2021\u5e74\u6691\u5047\u5f00\u59cb\uff0c\u9646\u7eed\u6709\u51e0\u4e2a\u6bd4\u8f83\u5927\u7684\u6570\u636e\u96c6\u76f8\u7ee7\u63a8\u51fa\uff0c\u6bd4\u5982Molecule3D\u548cPCQM4Mv2\u3002GeoSSL\u5c31\u662f\u5728Molecule3D\u4e0a\u8fdb\u884c\u9884\u8bad\u7ec3\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">GeoSSL\u662f\u4ec5\u4ec5\u8003\u8651\u5230geometry\u7684single-modality pretraining\u3002\u6211\u4eec\u9996\u5148\u9700\u8981\u5b9a\u4e49view\u3002\u8fd9\u91cc\u7684\u51fa\u53d1\u70b9\u662f\u5728\u8ba1\u7b97\u6216\u8005\u6a21\u62df\u4e2d\uff0c\u5206\u5b50\u76843D coordinates\u6709\u4e00\u5b9a\u7684\u8bef\u5dee\uff0c\u5e76\u4e14\u5206\u5b50\u76843D geometry \u54ea\u6015\u662f\u7a33\u5b9a\u6001<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u52bf\u80fd\u9762\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\uff0c\u4e5f\u4f1a\u5728\u4e00\u4e2a\u5c0f\u533a\u57df\u5185\u8fdb\u884c\u8fd0\u52a8\u3002\u7531\u6b64\uff0c\u6211\u4eec\u5b9a\u4e49\u4e86\u4e24\u4e2aview\uff1aoriginal geometry\u548cperturbed geometry\uff0c\u5982\u4e0b\u56fe\u6240\u793a\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.31675675675675674\" data-s=\"300,640\"  data-type=\"png\" data-w=\"925\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-fb9b8d6f1703e7e48d9ca14812a6c472.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe6\uff1a\u52bf\u80fd\u9762\u3001original geometry\u548cperturbed geometry\u793a\u610f\u56fe\u3002<\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u57fa\u4e8e\u8fd9\u4e24\u4e2aview\uff0c\u6211\u4eec\u53c8\u53ef\u4ee5\u5229\u7528\u516c\u5f0f1\u5f15\u51fa\u7684\u4e00\u7cfb\u5217\u65b9\u6cd5\u6765\u6700\u5927\u5316MI\u3002\u5df2\u6709\u7684\u65b9\u6cd5<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\"> (\u6bd4\u5982EBM-NCE\u3001InfoNCE\u3001RR)<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"> \u90fd\u5728GeoSSL\u4e2d\u8fdb\u884c\u4e86benchmark\u3002\u6b64\u5916\u6211\u4eec\u8fd8\u5229\u7528\u4e86geometry\u6570\u636e\u7684\u7279\u6027\uff0c\u4e5f\u5c31\u662f\u8fde\u7eed\u76843D coordinates\uff0c\u63d0\u51fa\u4e86\u5229\u7528denoising score matching\u7684\u65b9\u6cd5\uff0c\u6765\u8fdb\u884cdenoising distance matching\uff0c\u4ece\u800c\u5e2e\u52a9\u4e86\u53c2\u6570\u4f30\u8ba1\u3002\u5177\u4f53\u63a8\u5bfc\u8fc7\u7a0b\u53ef\u4ee5\u770b\u8bba\u6587\u3002\u5927\u6982\u6d41\u7a0b\u5219\u5982\u4e0b\u56fe\u6240\u793a\uff1a<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.4212962962962963\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-e61b4533c636573b083159da906bcbc4.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe7\uff1aGeoSSL\u7684\u6d41\u7a0b\u56fe\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<\/figure>\n<h3 data-into-catalog-status=\"\" style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(61, 170, 214);\"><strong><span style=\"font-size: 15px;\">2.4 \u5c0f\u7ed3<\/span><\/strong><\/span><\/h3>\n<section style=\"margin-bottom: 0px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.21851851851851853\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-cc515fa66fabeb52ad1492a152e6d74b.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe8\uff1a\u6211\u4eec\u5bf9\u4e8e\u6574\u4e2a\u516c\u5f0f1\u7684\u51e0\u79cd\u4e0d\u540c\u6c42\u89e3\u601d\u8def\u7684roadmap\u3002<\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5206\u5b50\u51e0\u4f55\u8868\u5f81\u5b66\u4e60<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08geometry representation learning\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u672c\u8eab\u5df2\u7ecf\u662f\u4e00\u4ef6\u6311\u6218\u6027\u540c\u65f6\u975e\u5e38\u91cd\u8981\u7684\u4efb\u52a1\uff0c\u56e0\u4e3ageometry\u662f\u8fd9\u4e9b\u7269\u7406\u7c92\u5b50\u6700\u672c\u8d28\u7684\u5e76\u4e14\u5f88\u590d\u6742\u7684\u6570\u636e\u7ed3\u6784\uff1b\u800cgeometry\u9884\u8bad\u7ec3\u4efb\u52a1\u7684\u590d\u6742\u6027\u66f4\u52a0\u5927\u4e00\u4e9b\u3002\u6211\u4eec\u56e2\u961f\u7684\u5de5\u4f5c\u4e00\u76f4\u5728\u63a2\u7d22\u76f8\u5173\u95ee\u9898\u3002\u4ece\u6700\u5f00\u59cb\u7684benchmark\uff0c\u4e00\u76f4\u5230\u9884\u8bad\u7ec3\uff0c\u6240\u6709\u7684\u4ee3\u7801\u9664\u4e86\u6bcf\u4e00\u4e2a\u5de5\u4f5c\u5404\u81ea\u7684github repo\u5f00\u6e90\uff0c\u4e5f\u5df2\u7ecf\u6574\u5408\u5230\u4e86Geom3D\u8fd9\u4e2a\u5e73\u53f0\u4e0a\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;\"><span style=\"outline: 0px;font-size: 15px;color: rgb(63, 63, 63);\">&nbsp;<\/span><\/section>\n<h3 style=\"outline: 0px;letter-spacing: 0.544px;white-space: normal;color: rgb(34, 34, 34);font-family: -apple-system, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);\">\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;letter-spacing: 0.544px;font-family: PingFangSC-light;text-align: right;font-size: 13px;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;outline: 0px;letter-spacing: 0.544px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;text-align: center;\">\n<section style=\"outline: 0px;display: inline-block;vertical-align: middle;\">\n<section style=\"margin-bottom: -2px;outline: 0px;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<section style=\"outline: 0px;clear: both;line-height: 0;\">\n<section style=\"outline: 0px;line-height: 0;width: 0px;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 10px;padding-left: 10px;outline: 0px;border-left: 3px solid rgb(33, 166, 210);border-right: 3px solid rgb(33, 166, 210);border-top-color: rgb(33, 166, 210);border-bottom-color: rgb(33, 166, 210);font-size: 16px;color: rgb(0, 0, 0);line-height: 1.4;\">\n<p style=\"outline: 0px;\"><strong style=\"color: rgb(61, 170, 214);letter-spacing: 0.578px;\"><span style=\"font-size: 15px;\">3 textual description modality enables more comprehensive tasks<\/span><\/strong><strong style=\"letter-spacing: 0.544px;outline: 0px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><strong style=\"outline: 0px;text-align: left;color: rgb(33, 166, 210);font-family: PingFangSC-light;letter-spacing: 0.544px;\"><\/strong><\/strong><\/p>\n<\/section>\n<section style=\"margin-top: -2px;outline: 0px;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;color: rgb(34, 34, 34);background-color: rgb(255, 255, 255);line-height: 1.75em;\"><span style=\"outline: 0px;color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">&nbsp;<\/span><\/section>\n<h3 data-into-catalog-status=\"\" style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(61, 170, 214);\"><strong><span style=\"font-size: 15px;\">3.1 GraphCG \u57fa\u4e8e\u56fe\u7684\u5206\u5b50\u7f16\u8f91 (\u53ef\u63a7\u751f\u6210)<\/span><\/strong><\/span><\/h3>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8be5\u7814\u7a76\u4ee5\u300aGraphCG: Unsupervised Discovery of Steerable Factors in Graphs\u300b\u4e3a\u9898\uff0c\u53d1\u8868\u5728NeurIPS GLFrontiers Workshop 2022 (oral) \u4e0a\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.43333333333333335\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-e204e36337df5070c35a870b7be575f8.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">GraphCG\u662f\u6211\u4eec\u7b2c\u4e00\u4e2a\u4f7f\u7528\u6df1\u5ea6\u5b66\u4e60\u6765\u8fdb\u884c\u53ef\u63a7\u751f\u6210\u7684\u5de5\u4f5c\u3002\u76ee\u524d\u5df2\u6709\u7684\u53ef\u63a7\u751f\u6210\u4e3b\u8981\u662f\u5bf9\u4e8e\u56fe\u7247\u7684\u64cd\u4f5c\uff0c\u800c\u6211\u4eec\u8ba4\u4e3a\uff0c\u5bf9\u4e8e\u5206\u5b50\u7684\u53ef\u63a7\u751f\u6210\uff0c\u53ef\u4ee5\u5f88\u597d\u5730\u7528\u4e8elead optimization\u7b49\u836f\u7269\u53d1\u73b0\u7684\u91cd\u8981\u4efb\u52a1\u4e2d\u3002\u95ee\u9898\u7684\u51fa\u53d1\u70b9\u662f\u8bf4\uff0c\u73b0\u6709\u7684lead optimization\u90fd\u9ad8\u5ea6\u4f9d\u8d56\u4e8e\u4e13\u5bb6\u7684\u7ecf\u9a8c\uff0c\u56e0\u6b64\u6bd4\u8f83\u8017\u8d39\u4eba\u529b\u5e76\u4e14\u6709\u4e00\u5b9a\u7684\u4e3b\u89c2\u6027\u3002\u800c\u5f53\u6211\u4eec\u5982\u679c\u80fd\u591f\u6210\u529f\u5229\u7528\u6df1\u5ea6\u5b66\u4e60\u7684\u65b9\u6cd5\uff0c\u6316\u6398\u51fa\u56fe\u751f\u6210\u6a21\u578b\u4e2d\u7684\u53ef\u63a7\u56e0\u5b50\uff0c\u90a3\u4e48\u5c31\u80fd\u591f\u63d0\u4f9b\u53e6\u5916\u4e00\u79cd lead optimization \u65b9\u6cd5\uff0c\u4ece\u800c\u5e2e\u52a9\u836f\u7269\u4e13\u5bb6\u8fdb\u884c\u7814\u53d1\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u95ee\u9898\u7684\u8bbe\u5b9a\u662f\u8bf4\u7ed9\u5b9a\u4e00\u4e2a\u5df2\u7ecf\u8bad\u7ec3\u5b8c\u6210\u7684\u56fe\u751f\u6210\u6a21\u578b\uff0c\u7136\u540e\u6211\u4eec\u4e3b\u8981\u8fdb\u884c\u4e86\u4e24\u4e2a\u6b65\u9aa4\u7684\u5206\u6790\uff1a<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(63, 63, 63);font-size: 15px;letter-spacing: 0.034em;\"><br  \/><\/span><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(63, 63, 63);font-size: 15px;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u9996\u5148\u6211\u4eec\u9a8c\u8bc1\u4e86\u5df2\u6709\u7684\u56fe\u751f\u6210\u6a21\u578b\uff0c\u90fd\u5728\u4e00\u5b9a\u7a0b\u5ea6\u4e0a\u662f\u9ad8\u5ea6\u8026\u5408\u7684 <\/span><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;color: rgb(136, 136, 136);\">(entangled)<\/span><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(63, 63, 63);font-size: 15px;letter-spacing: 0.034em;\">\u3002\u56e0\u4e3a\u9ad8\u5ea6\u8026\u5408\uff0c\u6240\u4ee5\u8981\u5b9e\u73b0\u53ef\u63a7\u751f\u6210\u5c31\u6bd4\u8f83\u6709\u6311\u6218\u6027\u3002<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u90a3\u4e48\u5bf9\u4e8e\u9ad8\u5ea6\u8026\u5408\u7684\u56fe\u751f\u6210\u6a21\u578b<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\"> (\u5df2\u7ecf\u8bad\u7ec3\u5b8c\u6bd5)<\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\uff0c\u5982\u679c\u6211\u4eec\u60f3\u5bf9\u5b83\u4eec\u8fdb\u884c\u53ef\u63a7\u751f\u6210\uff0c\u662f\u5426\u53ef\u884c\uff1f\u7b54\u6848\u662f\u53ef\u4ee5\u7684\uff0c\u6211\u4eec\u5bf9\u4e8e\u6b64\u63d0\u51fa\u4e86GraphCG\u3002<\/span><\/p>\n<section style=\"line-height: 1.75em;margin-left: 16px;margin-right: 16px;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u5728latent space\u4e2d\uff0c\u6211\u4eec\u6709\u4e0d\u540c\u7684semantic direction\uff0c\u800c\u6bcf\u4e00\u4e2asemantic direction\u90fd\u6709\u5404\u81ea\u5bf9\u5e94\u7684\u7279\u5b9a\u7684\u53ef\u63a7\u56e0\u5b50\u3002<\/span><\/section>\n<section style=\"line-height: 1.75em;margin-left: 16px;margin-right: 16px;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u5982\u679c\u6211\u4eec\u60f3\u5b66\u4e60\u5230\u8fd9\u4e9bsemantic direction\uff0c\u6211\u4eec\u5148\u6709\u4e00\u4e2a\u5047\u8bbe\uff1a\u4e0d\u540c\u7684\u56fe\uff0c\u5728latent space\u4e2d\u5982\u679c\u80fd\u591f\u6cbf\u7740\u4e00\u4e2asemantic direction\u79fb\u52a8\uff0c\u90a3\u4e48\u5b83\u4eec\u5c31\u4f1a\u6709\u5bf9\u5e94\u7684\u53ef\u63a7\u56e0\u5b50\u6539\u53d8<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\"> (\u6bd4\u5982\u67d0\u4e00\u4e2a\u56fe\u5b50\u7ed3\u6784\u53d8\u591a)<\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\u3002\u8fd9\u79cd\u5047\u8bbe\u53ef\u4ee5\u901a\u8fc7\u6700\u5927\u5316\u4e92\u4fe1\u606f\u6765\u5b9e\u73b0\u3002\u8fd9\u5c31\u56de\u5230\u4e86\u6211\u4eec\u7684\u516c\u5f0f1\u3002\u5177\u4f53\u6c42\u89e3\u7684\u65f6\u5019\uff0c\u6211\u4eec\u5229\u7528\u4e86NCE\u7684\u6c42\u89e3\u65b9\u6848\u3002\u8fd9\u6837\u6211\u4eec\u5c31\u5229\u7528\u6700\u5927\u5316\u4e92\u4fe1\u606f\u5b66\u5230\u4e86\u8fd9\u4e9bsemantic direction\u3002<\/span><\/section>\n<p style=\"margin-bottom: 0px;line-height: 1.75em;margin-left: 16px;margin-right: 16px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u5728inference\u8fc7\u7a0b\u4e2d\uff0c\u6211\u4eec\u53ea\u9700\u8981\u628a\u6bcf\u4e00\u4e2a\u56fe\u5bf9\u5e94\u7684 latent representation \u6cbf\u7740 semantic direction \u8fdb\u884c\u79fb\u52a8\uff0c\u7136\u540e\u8fdb\u884c\u89e3\u7801\uff0c\u8fd9\u4e2a\u89e3\u7801\u4e4b\u540e\u7684\u56fe\u5c31\u662f\u6211\u4eec\u5e0c\u671b\u7684\u67d0\u4e00\u4e2a\u56e0\u5b50\u6539\u53d8\u7684\u56fe\u3002<\/span><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.27870370370370373\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-310819d1f2c2f3b2866bebd6c08a9e3c.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe9\uff1aGraphCG\u7684\u5b66\u4e60\u548c\u63a8\u7406\u6d41\u7a0b\u56fe\u3002<\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5177\u4f53\u5b9a\u91cf\u7ed3\u679c\u53ef\u4ee5\u53c2\u8003\u539f\u6587\uff0c\u8fd9\u91cc\u6211\u4eec\u4e3b\u8981\u5c55\u793a\u5b9a\u6027\u7ed3\u679c\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u9996\u5148\u5728\u5206\u5b50\u56fe\uff0c\u6211\u4eec\u5229\u7528\u4e86\u5df2\u7ecf\u8bad\u7ec3\u597d\u7684HierVAE\uff0c\u5728\u5b83\u7684 latent space\u4e0a\u8bad\u7ec3\u5f97\u5230\u4e8610\u4e2asemantic direction\u3002\u7136\u540e\u6211\u4eec\u53d1\u73b0\u5176\u4e2d\u56db\u4e2asemantic direction\u90fd\u80fd\u5bf9\u5e94\u5230\u4e13\u95e8\u7684\u5206\u5b50\u5b98\u80fd\u56e2\u3002\u8fd9\u4e2a\u5f88\u597d\u5730\u7b26\u5408\u4e86\u6211\u4eec\u7684\u671f\u671b\uff0c\u5e76\u4e14\u4e5f\u80fd\u591f\u5e2e\u52a9\u836f\u7269\u4e13\u5bb6\u8fdb\u884clead optimization\u8bbe\u8ba1\uff1a\u6bd4\u5982\u5e0c\u671b\u5bf9\u539f\u59cb\u5206\u5b50\u56fe\u589e\u52a0\/\u51cf\u5c11\u66f4\u591a\u7684halogen\u57fa\u56e2\uff0c\u89c1\u56fe10(a)\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.45185185185185184\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-81277e92c3ed5f15c53a65e45c4912c4.png\"  \/><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.5em;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe10\uff1aGraphCG\u5728\u5206\u5b50\u56fe\u4e0a\u7f16\u8f91\u7684\u7ed3\u679c\u3002\u6bcf\u4e00\u884c\u7684\u4e94\u4e2a\u683c\u5b50\u5bf9\u5e94\u4e86\u4e00\u4e2a\u5206\u5b50\u7684\u4e94\u4e2a\u7f16\u8f91\u6b65\u957f\uff1a\u4ece\u5de6\u5230\u53f3\u4f9d\u6b21\u4e3a{-3, -1.8, 0, 1.8, 3}\u3002\u5176\u4e2d0\uff08\u4e5f\u5c31\u662f\u4e2d\u5fc3\u683c\u5b50\uff09\u8868\u793a\u539f\u59cb\u5206\u5b50\u3002\u6211\u4eec\u5c55\u793a\u4e86\u56db\u4e2a\u7f16\u8f91\u65b9\u5411\uff0c\u5bf9\u5e94\u4e8ea\u5230d\u3002<\/span><\/p>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5176\u6b21\u6211\u4eec\u8fd8\u5c55\u793a\u4e86\u57fa\u4e8ePointFlow\u7684\u70b9\u4e91\u56fe\u7684\u53ef\u63a7\u7ed3\u679c\u3002\u4e0b\u56fe\u4e2d\u7684a\u548cb\u662f\u4e00\u4e2a\u65b9\u5411\uff0c\u5e76\u4e14\u6211\u4eec\u80fd\u770b\u5230\u5f80\u5de6\u5f80\u53f3\u4e24\u4e2a\u4e0d\u540c\u7684\u65b9\u5411\uff0c\u5bf9\u5e94\u7684\u98de\u673a\u5f15\u64ce\u6570\u76ee\u4f1a\u5206\u522b\u51cf\u5c11\u548c\u589e\u52a0\u3002\u6b64\u5916\u5728\u8f66\u5b50\u548c\u6905\u5b50\u7684\u5916\u5f62\u4e5f\u4f1a\u968f\u7740\u53ef\u63a7\u56e0\u5b50\uff0c\u6709\u5bf9\u5e94\u7684\u6539\u53d8\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.4935185185185185\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-423adea501f8cb6d433604b08c4cd6fc.png\"  \/><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.5em;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe11\uff1aGraphCG\u5728\u70b9\u4e91\u4e0a\u7f16\u8f91\u7684\u7ed3\u679c\u3002\u6bcf\u4e00\u884c\u7684\u4e94\u4e2a\u683c\u5b50\u5bf9\u5e94\u4e86\u4e00\u4e2a\u5206\u5b50\u7684\u4e94\u4e2a\u7f16\u8f91\u6b65\u957f\uff1a\u4ece\u5de6\u5230\u53f3\u4f9d\u6b21\u4e3a{-3, -1.8, 0, 1.8, 3}\u3002\u5176\u4e2d0\uff08\u4e5f\u5c31\u662f\u4e2d\u5fc3\u683c\u5b50\uff09\u8868\u793a\u539f\u59cb\u70b9\u4e91\u3002\u6211\u4eec\u5c55\u793a\u4e86\u4e09\u4e2a\u7f16\u8f91\u65b9\u5411\uff0c\u5bf9\u5e94\u4e8e\u4e09\u4e2a\u4e0d\u540c\u7684\u9884\u8bad\u7ec3\u751f\u6210\u6a21\u578b\u3002<\/span><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">GraphCG\u7684\u521d\u6b65\u5c1d\u8bd5\u7ed9\u6211\u4eec\u5e26\u6765\u4e86\u975e\u5e38\u5927\u7684\u4fe1\u5fc3\uff0c\u8ba9\u6211\u4eec\u5bf9\u4e8e\u5206\u5b50\u7684\u53ef\u63a7\u751f\u6210\u6709\u4e86\u66f4\u5927\u7684\u628a\u63e1\u3002\u5b83\u4e5f\u5f15\u5bfc\u4e86\u6211\u4eec\u540e\u7eed\u7684\u51e0\u4e2a\u5de5\u4f5c\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<h3 data-into-catalog-status=\"\" style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(61, 170, 214);\"><strong><span style=\"font-size: 15px;\">3.2 MoleculeSTM \u57fa\u4e8e\u6587\u672c\u7684\u5206\u5b50\u7f16\u8f91<\/span><\/strong><\/span><\/h3>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8be5\u7814\u7a76\u4ee5\u300aMulti-modal Molecule Structure-text Model for Text-based Editing and Retrieval\u300b\u4e3a\u9898\uff0c\u53d1\u8868\u5728ArXiv\u4e0a\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.4083333333333333\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-93fbc81e2d7b4cd1937e047b3a275d24.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u6700\u8fd1\u968f\u7740\u5927\u6a21\u578b\u3001\u591a\u6a21\u6001\u7684\u5e94\u7528\uff0c\u4e00\u4e2a\u5f88\u81ea\u7136\u7684\u60f3\u6cd5\u5c31\u662f\u6211\u4eec\u662f\u5426\u4e5f\u53ef\u4ee5\u5c06\u8fd9\u4e9b\u6280\u672f\u7528\u5230\u836f\u7269\u53d1\u73b0\u4e0a\uff1f\u5e76\u4e14\u8fd9\u4e9b\u81ea\u7136\u8bed\u8a00\u7684\u6587\u672c\u63cf\u8ff0\uff0c\u662f\u5426\u5bf9\u4e8e\u836f\u7269\u53d1\u73b0\u8fd9\u4e2a\u6709\u6311\u6218\u6027\u7684\u95ee\u9898\u5e26\u6765\u65b0\u7684\u89c6\u89d2\uff1f\u7b54\u6848\u662f\u80af\u5b9a\u5e76\u4e14\u4e50\u89c2\u7684\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5177\u4f53\u5230\u65b9\u6cd5\u4e0a\u3002MoleculeSTM\u7684\u6838\u5fc3\u601d\u8def\u975e\u5e38\u7b80\u5355\u76f4\u63a5\uff1a\u5206\u5b50\u7684\u63cf\u8ff0\u6709\u5185\u90e8\u5316\u5b66\u7ed3\u6784\u548c\u5916\u90e8\u529f\u80fd\u63cf\u8ff0\u4e24\u5927\u7c7b\uff0c\u800c\u6211\u4eec\u8fd9\u91cc\u5229\u7528\u4e86multi-modal learning\u7684\u601d\u8def\uff0c\u5c06\u4e24\u79cd\u7c7b\u578b\u7684\u4fe1\u606f\u8fdb\u884c\u8054\u7cfb\uff0c\u5e76\u4e14\u57fa\u4e8e\u6b64\u6211\u4eec\u8bbe\u8ba1\u4e86\u79cd\u7c7b\u4e30\u5bcc\u7684\u4e0b\u6e38\u4efb\u52a1\u6765\u9a8c\u8bc1\u5176\u6709\u6548\u6027\u3002\u8fd9\u91cc\u9884\u8bad\u7ec3\u7684\u601d\u8def\u8fd8\u662f\u901a\u8fc7\u6c42\u89e3\u516c\u5f0f1\u6765\u7ed9\u4e24\u4e2a\u6a21\u6001<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">\uff08\u5bf9\u5e94\u7684\u8868\u5f81\u51fd\u6570\uff09<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8fdb\u884c\u94fe\u63a5\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img js_insertlocalimg\" data-ratio=\"0.7638888888888888\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-5c7a5628d5cd28cae7686f04ca2748dc.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe12\uff1aMoleculeSTM\u7684\u6d41\u7a0b\u56fe\u3002<\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u4e0b\u9762\u6211\u4eec\u4e3b\u8981\u5f3a\u8c03\u51e0\u4e2ainsight\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><strong><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">3.2.1 \u81ea\u7136\u8bed\u8a00\u548c\u5927\u8bed\u8a00\u6a21\u578b\u6709\u4ec0\u4e48\u7279\u70b9\u80fd\u591f\u5e2e\u52a9 scientific discovery\uff1f<\/span><\/strong><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8fd9\u4e2a\u662f\u6211\u4eec\u5728MoleculeSTM\u4e2d\u9996\u5148\u63d0\u51fa\u7684\u95ee\u9898\u3002\u5728MoleculeSTM\u8fd9\u4e2a\u5de5\u4f5c\u91cc\uff0c\u6211\u4eec\u662f\u5229\u7528\u4e86\u81ea\u7136\u8bed\u8a00\u7684open vocabulary\u548ccompositionality\u7279\u6027\u3002<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022 open vocabulary\u662f\u8bf4\u6211\u4eec\u5bf9\u4e8e\u836f\u7269\u7684\u63cf\u8ff0\u53ef\u4ee5\u975e\u5e38\u7684\u591a\u6837\uff0c\u6bd4\u5982\u4e00\u4e2a\u6781\u7aef\u4f8b\u5b50\u662f\u201c\u5f00\u53d1\u4e00\u4e2a\u836f\u7269\u80fd\u591f\u6cbb\u7597\u660e\u5e74\u7684\u7a81\u53d1\u7684xxx\u75be\u75c5\u201d\u8fd9\u6837\u7684text prompt\uff0c\u53ea\u4e0d\u8fc7\u8fd9\u79cdtext prompt\u662f\u96be\u4ee5\u9a8c\u8bc1\uff0c\u5e76\u4e14\u5bf9\u4e8e\u76ee\u6807\u7684\u63cf\u8ff0\u8fc7\u4e8e\u6a21\u7cca\u3002<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022 compositionality\u662f\u8bf4\u6211\u4eec\u6709\u4e00\u4e9b\u6bd4\u8f83\u590d\u6742\u7684\u591a\u76ee\u6807\u4efb\u52a1\uff0c\u4f46\u662f\u5982\u679c\u5728\u81ea\u7136\u8bed\u8a00\u4e2d\uff0c\u5b83\u66f4\u5bb9\u6613\u7ec4\u5408\u3002\u4e00\u4e2a\u4f8b\u5b50\u662f\u591a\u5c5e\u6027\u7684lead optimization\uff0c\u4e5f\u5c31\u662f\u8ba9\u4e00\u4e2a\u5206\u5b50\u4f18\u5316\u5230\u540c\u65f6\u7b26\u5408\u591a\u4e2a\u5c5e\u6027\uff1b\u4f20\u7edf\u505a\u6cd5\u4f1a\u9700\u8981\u5bf9\u6bcf\u4e00\u4e2a\u5c5e\u6027\u8bad\u7ec3\u4e00\u4e2a\u5206\u7c7b\u5668\uff0c\u800cMoleculeSTM\u4ec5\u4ec5\u53ea\u9700\u8981\u628a\u4e24\u4e2a\u5c5e\u6027\u7528\u81ea\u7136\u8bed\u8a00\u63cf\u8ff0\u7136\u540e\u901a\u8fc7\u201cand\u201d\u8fde\u63a5\u5373\u53ef\u3002<\/span><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u5728\u6211\u4eec\u6700\u8fd1\u7684\u5de5\u4f5cChatDrug\u4e2d\uff0c\u6211\u4eec\u53c8\u6316\u6398\u4e86\u81ea\u7136\u8bed\u8a00\u548c\u5927\u8bed\u8a00\u6a21\u578b\u7684\u5bf9\u8bdd\u7279\u6027\u3002\u8fd9\u4e2a\u4f1a\u5728\u4e0b\u9762\u5c55\u5f00\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><strong><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">3.2.2 \u81ea\u7136\u8bed\u8a00\u548c\u5927\u8bed\u8a00\u6a21\u578b\u7684\u7279\u70b9\u80fd\u591f\u5e2e\u52a9\u4ec0\u4e48\u7c7b\u578b\u7684 scientific discovery \u4efb\u52a1\uff1f<\/span><\/strong><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u73b0\u6709\u7684language-image task\u53ef\u4ee5\u8ba4\u4e3a\u662f\u827a\u672f\u76f8\u5173\u7684\u4efb\u52a1<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\"> (\u6bd4\u5982\u751f\u6210\u56fe\u7247\u3001\u6587\u5b57)<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\uff0c\u4e5f\u5c31\u662f\u8bf4\u5b83\u4eec\u7684\u7ed3\u679c\u662f\u53ef\u4ee5\u591a\u6837\u548c\u4e0d\u786e\u5b9a\u3002\u4f46\u662fscientific discovery\u662f\u79d1\u5b66\u95ee\u9898\uff0c\u901a\u5e38\u6709\u7740\u6bd4\u8f83\u660e\u786e\u7684\u7ed3\u679c\uff0c\u6bd4\u5982\u751f\u6210\u6709\u67d0\u4e2a\u529f\u6548\u7684\u5c0f\u5206\u5b50\u3002\u8fd9\u4e2a\u5728\u4efb\u52a1\u7684\u8bbe\u8ba1\u4e0a\u5e26\u6765\u4e86\u66f4\u5927\u7684\u6311\u6218\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5728MoleculeSTM\u4e2d <\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">(Appendix B)<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\uff0c\u6211\u4eec\u63d0\u51fa\u4e86\u4e24\u4e2a\u51c6\u5219\uff1a<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u9996\u5148\u6211\u4eec\u8003\u8651\u7684\u4efb\u52a1\u662f\u80fd\u591f\u8fdb\u884c\u8ba1\u7b97\u6a21\u62df\u5f97\u5230\u7ed3\u679c\u3002\u5c06\u6765\u4f1a\u8003\u8651\u80fd\u591f\u6709wet-lab\u9a8c\u8bc1\u7684\u7ed3\u679c\uff0c\u4f46\u8fd9\u5e76\u4e0d\u5728\u76ee\u524d\u8fd9\u4e2a\u5de5\u4f5c\u7684\u8003\u91cf\u8303\u7574\u5185\u3002<\/span><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u5176\u6b21\u6211\u4eec\u53ea\u8003\u8651\u6709\u7740\u6a21\u7cca\u6027\u7ed3\u679c\u7684\u95ee\u9898<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\">\uff08\u95ee\u9898\u7684\u63cf\u8ff0\u662f\u76f8\u5bf9\u6a21\u7cca\u7684\uff0c\u4f46\u662f\u7b54\u6848\u662f\u76f8\u5bf9\u786e\u5b9a\u7684\uff09<\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\u3002\u5177\u4f53\u4f8b\u5b50\u6bd4\u5982\u8ba9\u67d0\u4e2a\u5206\u5b50\u7684\u6c34\u6eb6\u6027\u6216\u8005\u7a7f\u900f\u6027\u53d8\u5f3a\u3002\u800c\u6709\u4e00\u4e9b\u95ee\u9898\u6709\u660e\u786e\u7ed3\u679c\uff0c\u6bd4\u5982\u5728\u5206\u5b50\u7684\u67d0\u4e00\u4e2a\u4f4d\u7f6e\u52a0\u5165\u67d0\u4e00\u4e2a\u5b98\u80fd\u56e2\uff0c\u6211\u4eec\u8ba4\u4e3a\u8fd9\u7c7b\u4efb\u52a1\u5bf9\u4e8e\u836f\u7269\u3001\u5316\u5b66\u4e13\u5bb6\u6765\u8bf4\u66f4\u52a0\u7b80\u5355\u76f4\u63a5\uff0c\u800cDL\u7684\u5e2e\u52a9\u6bd4\u8f83\u6709\u9650\uff1b\u6240\u4ee5\u5b83\u53ef\u4ee5\u5c06\u6765\u5f53\u4f5c\u67d0\u4e00\u4e2aproof-of-concept\u4efb\u52a1\uff0c\u4f46\u662f\u5e76\u4e0d\u4f1a\u6210\u4e3a\u4e3b\u8981\u7684\u4efb\u52a1\u76ee\u6807\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><strong><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">3.2.3 \u5206\u5b50\u7f16\u8f91\u7684\u5b9a\u6027\u7ed3\u679c<\/span><\/strong><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">MoleculeSTM\u7684\u6587\u7ae0\u4e2d\u6211\u4eec\u5f15\u5165\u4e86\u4e09\u7c7b\u4e0b\u6e38\u4efb\u52a1\uff0c\u6765\u9a8c\u8bc1MoleculeSTM\u7684\u6709\u6548\u6027\u3002\u8fd9\u91cc\u6211\u4eec\u4e3b\u8981\u60f3\u5f3a\u8c03\u4e00\u4e0bzero-shot text-guided molecule editing\u7684\u5b9a\u6027\u7ed3\u679c\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8fd9\u4e2atask\u5c31\u662f\u540c\u65f6\u8f93\u5165\u4e00\u4e2a\u5206\u5b50\u548c\u81ea\u7136\u8bed\u8a00\u63cf\u8ff0<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\"> (\u6bd4\u5982\u989d\u5916\u7684\u5c5e\u6027)<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\uff0c\u7136\u540e\u5e0c\u671b\u80fd\u591f\u8f93\u51fa\u7b26\u5408\u8bed\u8a00\u6587\u672c\u63cf\u8ff0\u7684\u65b0\u7684\u5206\u5b50\u3002\u8fd9\u4e5f\u662ftext-guided lead optimization\uff0c\u4e00\u79cd\u65b0\u7684lead optimization\u8303\u5f0f\u3002<\/p>\n<p>\u5177\u4f53\u7684\u65b9\u6cd5\u5c31\u662f\u5229\u7528\u5df2\u7ecf\u8bad\u7ec3\u597d\u7684\u5206\u5b50\u6df1\u6210\u6a21\u578b\u548c\u6211\u4eec\u9884\u8bad\u7ec3\u597d\u7684MoleculeSTM\uff0c\u901a\u8fc7\u5b66\u4e60\u4e8c\u8005\u7684latent space\u7684alignment\uff0c\u4ece\u800c\u8fdb\u884c latent space interpolation\uff0c\u518d\u7ecf\u8fc7\u89e3\u7801\u751f\u6210\u76ee\u6807\u5206\u5b50\u3002\u6d41\u7a0b\u793a\u610f\u56fe\u5982\u4e0b\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.3490740740740741\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-2be5658b22ac9e557ce74de0d7bb8c61.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe13\uff1azero-shot text-guided molecule editing \u4e24\u9636\u6bb5\u6d41\u7a0b\u793a\u610f\u56fe\u3002<\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8fd9\u91cc\u6211\u4eec\u5c55\u793a\u4e86\u51e0\u7ec4\u5206\u5b50\u7f16\u8f91\u7684\u5b9a\u6027\u7ed3\u679c<\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\"> (\u5176\u4f59\u4e0b\u6e38\u4efb\u52a1\u7684\u7ed3\u679c\u7ec6\u8282\u53ef\u4ee5\u53c2\u8003\u539f\u8bba\u6587)&nbsp;<\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002\u4e3b\u8981\u6211\u4eec\u8003\u8651\u56db\u7c7b\u5206\u5b50\u7f16\u8f91\u4efb\u52a1\uff1a<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u5355\u4e00\u5c5e\u6027\u7f16\u8f91\uff1a\u5bf9\u5355\u4e00\u5c5e\u6027\u8fdb\u884c\u7f16\u8f91\uff0c\u6bd4\u5982\u6c34\u6eb6\u6027\u3001\u7a7f\u900f\u6027\u3001\u6c22\u952e\u65bd\u4e3b\u4e0e\u53d7\u4e3b\u4e2a\u6570\u3002- \u590d\u5408\u5c5e\u6027\u7f16\u8f91\uff1a\u540c\u65f6\u5bf9\u591a\u4e2a\u5c5e\u6027\u8fdb\u884c\u7f16\u8f91\uff0c\u6bd4\u5982\u6c34\u6eb6\u6027\u548c\u6c22\u952e\u65bd\u4e3b\u4e2a\u6570\u3002<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u836f\u7269\u76f8\u4f3c\u6027\u7f16\u8f91\uff1a<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\">(Appendix D.5) <\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\u662f\u8ba9\u8f93\u5165\u5206\u5b50\u4e0e\u76ee\u6807\u5206\u5b50\u836f\u7269\u957f\u5f97\u66f4\u52a0\u63a5\u8fd1\u3002<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u4e13\u5229\u836f\u7269\u7684\u90bb\u5c45\u641c\u7d22\uff1a\u5bf9\u4e8e\u5df2\u7ecf\u7533\u8bf7\u5230\u4e13\u5229\u7684\u836f\u7269\uff0c\u5f80\u5f80\u4f1a\u628a\u4e2d\u95f4\u8fc7\u7a0b\u7684\u836f\u7269\u4e00\u8d77\u62a5\u9053\u3002\u6211\u4eec\u8fd9\u91cc\u5c31\u662f\u90a3\u4e2d\u95f4\u836f\u7269\u914d\u5408\u81ea\u7136\u8bed\u8a00\u63cf\u8ff0\uff0c\u770b\u662f\u5426\u80fd\u591f\u751f\u6210\u6700\u7ec8\u7684\u76ee\u6807\u836f\u7269\u3002<\/span><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022 binding affinity\u7f16\u8f91\uff1a\u6211\u4eec\u9009\u62e9\u51e0\u4e2aChEMBL assay\u4f5c\u4e3atarget\uff0c\u76ee\u6807\u662f\u8ba9\u8f93\u5165\u5206\u5b50\u548ctarget\u6709\u66f4\u9ad8\u7684binding affinity\u3002<\/span><\/section>\n<figure data-size=\"normal\">\n<p><br  \/><\/p>\n<section style=\"text-align: center;margin-left: 16px;margin-right: 16px;\"><img class=\"rich_pages wxw-img js_insertlocalimg\" data-ratio=\"0.9472222222222222\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-322f1a386bdbeba7d01ea11f72656b16.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe14: zero-shot text-guided molecule editing \u7ed3\u679c\u5c55\u793a\u3002<\/span><\/section>\n<\/figure>\n<h3 data-into-catalog-status=\"\" style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/h3>\n<h3 data-into-catalog-status=\"\" style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(61, 170, 214);\"><strong><span style=\"font-size: 15px;\">3.3 ProteinDT \u57fa\u4e8e\u6587\u672c\u7684\u86cb\u767d\u8d28\u751f\u6210\u548c\u7f16\u8f91<\/span><\/strong><\/span><\/h3>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8be5\u7814\u7a76\u4ee5\u300aA Text-guided Protein Design Framework\u300b\u4e3a\u9898\uff0c\u53d1\u8868\u5728ArXiv\u4e0a\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<p style=\"text-align: center;margin-left: 8px;margin-right: 8px;margin-bottom: 0px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.2111111111111111\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-b2291d3a6e2de83fc7f25ec4662222dc.png\"  \/><\/p>\n<figure data-size=\"normal\">\n<p style=\"text-align: center;\"><img class=\"rich_pages wxw-img js_insertlocalimg\" data-ratio=\"0.9340232858990944\" data-s=\"300,640\"  data-type=\"png\" data-w=\"773\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-33c9dd30fb54e2b4222fe81407c844ab.png\"  \/><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe15\uff1aProteinDT\u6d41\u7a0b\u56fe\u3002<\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">MoleculeSTM\u7684\u521d\u6b65\u63a2\u7d22\u8ba9\u6211\u4eec\u611f\u53d7\u5230\u6587\u672c\u63cf\u8ff0\u7684\u6f5c\u5728\u7528\u9014\u662f\u80fd\u591f\u63d0\u4f9b\u66f4\u591a\u89e3\u51b3\u95ee\u9898\u7684\u89c6\u89d2\u3002\u8fd9\u4e2a\u5de5\u4f5c\u6211\u4eec\u5c31\u5f88\u81ea\u7136\u7684\u5c06\u8fd9\u4e2a\u60f3\u6cd5\u62d3\u5c55\u5230\u86cb\u767d\u8d28\u9886\u57df\u4e0a\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u9996\u5148\u5728\u9884\u8bad\u7ec3\u4e0a\uff0cProteinDT\u4e3b\u8981\u5206\u4e3a\u4e09\u6b65\uff1a<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u7b2c\u4e00\u6b65ProteinCLAP\uff0c\u662f\u5c06text sequence\u548cprotein sequence\u901a\u8fc7contrastive learning\u6765\u5b66\u4e60alignment\u3002<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u7b2c\u4e8c\u6b65Facilitator\uff0c\u662f\u8fdb\u4e00\u6b65\u589e\u5f3aalignment\u3002<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u524d\u4e24\u4e2a\u6b65\u9aa4\u90fd\u662f\u901a\u8fc7latent space\u64cd\u4f5c\uff0c\u800c\u7b2c\u4e09\u6b65deconder\u5219\u662f\u5c06latent representation\u89e3\u7801\u5230data space\u3002\u9700\u8981\u63d0\u5230\u7684\u662f\u6211\u4eec\u8fd9\u91cc\u8003\u8651\u4e86\u4e24\u7c7bdecoder\uff1aauto-regressive\u548cdenoising diffusion<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\"> (\u5982\u4e0b\u56fe)<\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\"> \u3002<\/span><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u8fd9\u91cc\u6211\u4eec\u8fd8\u60f3\u8981\u5f3a\u8c03\u7684\u662f\uff0cTransformer\u5e76\u4e0d\u662f\u751f\u6210\u6a21\u578b\uff0c\u800c\u4ec5\u4ec5\u662f\u4e00\u4e2a\u6df1\u5ea6\u5b66\u4e60\u6a21\u5757\u3002\u6211\u4eec\u7684\u4e24\u79cd\u751f\u6210\u6a21\u578b\u90fd\u8003\u8651\u4e86\u7528Transformer\u4f5c\u4e3a\u6838\u5fc3\u6a21\u5757\u7684\u60c5\u51b5\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.3138888888888889\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-b9281487692dd4261ed4925c6b3af951.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe16\uff1aProteinDT\u4e2d\u8003\u8651\u5230\u7684\u4e24\u5927\u7c7b\u6761\u4ef6\u751f\u6210\u6a21\u578b\u3002<\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><strong><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">3.3.1 Text-to-Protein Generation<\/span><\/strong><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u5f53\u6211\u4eec\u6709\u4e86\u4e0a\u8ff0\u7684\u6d41\u7a0b\u56fe\u4e4b\u540e\uff0c\u5c31\u53ef\u4ee5\u8fdb\u884ctext-to-protein generation\u7684\u751f\u6210 <\/span><span style=\"font-size: 15px;color: rgb(136, 136, 136);\">(\u5982\u4e0b\u56fe) <\/span><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u3002\u5e76\u4e14\u6211\u4eec\u8fd8\u8fdb\u884c\u4e86\u6d88\u878d\u5b9e\u9a8c\u8bc1\u660e\u4e86facilitator\u6a21\u5757\u7684\u5fc5\u8981\u6027\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.2037037037037037\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-2083dba923e71d95bc3e2266e7fd40a3.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe17\uff1atext-to-protein structure\u751f\u6210\u8fc7\u7a0b\u3002<\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><strong><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">3.3.2 Text-guided Protein Editing<\/span><\/strong><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8fd9\u91cc\u57fa\u4e8eProteinCLAP\uff0c\u6211\u4eec\u63d0\u51fa\u4e86\u4e24\u79cdprotein editing\u601d\u8def\u3002<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022 latent interpolation\u662f\u76f4\u63a5\u5728latent space\u8fdb\u884c\u63a7\u5236interpolation\uff0c\u7136\u540e\u76f4\u63a5\u89e3\u7801\u5230protein sequence space\u3002<\/span><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022 latent optimization\u5219\u662f\u4e13\u95e8\u8bad\u7ec3\u4e00\u4e2atoken-level\u7684\u89e3\u7801\u5668\uff0c\u7136\u540e\u5229\u7528ProteinCLAP\u76f4\u63a5\u4f18\u5316\u5f97\u5230optimal latent\uff0c\u518d\u901a\u8fc7\u89e3\u7801\u5230protein sequence space\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.2351851851851852\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-844eae1e774a3b0728a3642183b2ec32.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe18\uff1a\u4e24\u79cd text-guided protein editing \u65b9\u6cd5\u6d41\u7a0b\u793a\u610f\u56fe\u548c\u6bd4\u8f83\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<\/figure>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.5819047619047619\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1050\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-bc0aadd3d14c3c0dc44fe437516aa059.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe 19\uff1atext-guided protein editing inference \u6d41\u7a0b\u793a\u610f\u56fe\u3002<\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u6574\u4e2atext-guided protein editing\u7684inference\u6d41\u7a0b\u56fe\u5982\u56fe19\u3002\u66f4\u591a\u5b9a\u91cf\u5b9e\u9a8c\u7ed3\u679c\u53ef\u4ee5\u53c2\u8003\u539f\u6587\u3002<\/span><\/section>\n<h3 data-into-catalog-status=\"\" style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/h3>\n<h3 data-into-catalog-status=\"\" style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(61, 170, 214);\"><strong><span style=\"font-size: 15px;\">3.4 ChatDrug \u57fa\u4e8eChatGPT\u5bf9\u8bdd\u589e\u5f3a\u7684\u5c0f\u5206\u5b50\u3001\u591a\u80bd\u3001\u86cb\u767d\u8d28\u7f16\u8f91<\/span><\/strong><\/span><\/h3>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8be5\u7814\u7a76\u4ee5\u300aChatGPT-powered Conversational Drug Editing Using Retrieval and Domain Feedback\u300b\u4e3a\u9898\uff0c\u53d1\u8868\u5728ArXiv\u4e0a\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.39351851851851855\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-81d09a87d57cc479f54736cff5edd232.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u57282022\u5e74\u768411\u6708\uff0cChatGPT\u63a8\u51fa\u3002\u7d27\u63a5\u7740\u5f88\u591a\u9886\u57df\u3001\u5e94\u7528\u90fd\u5f00\u59cb\u5c1d\u8bd5\u4f7f\u7528\u8fd9\u4e2a\u57fa\u4e8e\u5927\u6a21\u578b\u7684\u5de5\u5177\uff0c\u5e76\u4e14\u53d1\u73b0\u4e86\u5b83\u7684\u786e\u80fd\u591f\u4f18\u96c5\u5730\u89e3\u51b3\u5f88\u591a\u95ee\u9898\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8fd9\u4e2a\u5de5\u4f5c\u4e2d\uff0c\u6211\u4eec\u5c31\u5c1d\u8bd5<strong>\u5c06ChatGPT\u7528\u4e8e\u836f\u7269\u53d1\u73b0<\/strong>\u3002\u9996\u5148\u4e00\u4e2a\u6bd4\u8f83\u6709\u6311\u6218\u6027\u7684\u74f6\u9888\u8fd8\u662f\u5982\u4f55\u8bbe\u8ba1\u4efb\u52a1\u3002\u6211\u4eec\u8ddf\u968fMoleculeSTM\u548cProteinDT\u7684insight\uff0c\u4e3b\u8981\u5bf9\u6807drug editing\u7cfb\u5217\u4efb\u52a1\uff0c\u5e76\u4e14\u6211\u4eec\u5728\u8fd9\u91cc\u8003\u8651\u4e86\u4e09\u79cd\u7c7b\u578b\u7684\u836f\u7269\uff1a\u5c0f\u5206\u5b50\u3001\u591a\u80bd\u3001\u86cb\u767d\u8d28\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.3388888888888889\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-9f1270c339a17ddf432591eae210be1c.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe20\uff1aChatDrug\u6d41\u7a0b\u56fe\u3002<\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u6839\u636eChatGPT\u7684\u7279\u6027\uff0c\u6211\u4eec\u63d0\u51fa\u4e86ChatDrug\uff0c\u5b83\u4e3b\u8981\u6709\u4e09\u4e2a\u6a21\u5757\uff1a<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022 PDDS\u6a21\u5757\u662f\u9488\u5bf9domain task\u8bbe\u8ba1\u7684prompt\u3002<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022 ReDF\u6a21\u5757\u662f\u5229\u7528retrieval\u548cdomain feedback\u5bf9prompt\u8fdb\u884c\u66f4\u65b0\u3002<\/span><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022 conversation module\u662f\u8ba9\u7528\u6237\u548cChatDrug\u8fdb\u884c\u4ea4\u4e92\uff0c\u4ece\u800c\u4e0d\u65ad\u66f4\u65b0\u7ed3\u679c\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u4e0b\u9762\u6211\u4eec\u5217\u51fa\u4e3b\u8981\u7684\u5b9a\u6027\u7ed3\u679c\u3002\u5173\u4e8e\u66f4\u8be6\u7ec6\u7684\u4efb\u52a1\u8bbe\u5b9a\u548c\u5b9a\u91cf\u7ed3\u679c\uff0c\u611f\u5174\u8da3\u7684\u670b\u53cb\u53ef\u4ee5\u770b\u6587\u7ae0\u7ec6\u8282\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022 ChatDrug \u5c0f\u5206\u5b50\u7f16\u8f91\u5b9a\u6027\u7ed3\u679c\uff1a<\/span><\/section>\n<section style=\"margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.49537037037037035\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-fe5a6ef1f756985e7b7c7167fdbfca2d.png\"  \/><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.5em;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe 21\uff1aChatDrug\u5728\u5c0f\u5206\u5b50\u7f16\u8f91\u7684\u7ed3\u679c\u3002\u4efb\u52a1\u662f\u5173\u4e8e\u5c0f\u5206\u5b50\u5355\/\u591a\u5c5e\u6027\u4f18\u5316\uff0c\u5177\u4f53\u63cf\u8ff0\u5728\u5bf9\u5e94\u8868\u683c\u4e2d\u3002\u84dd\u8272\u3001\u7ea2\u8272\u548c\u7eff\u8272\u5206\u522b\u8868\u793a\u7f16\u8f91\u8fc7\u7a0b\u7684\u521d\u59cb\u72b6\u6001\u3001\u4e2d\u95f4\u72b6\u6001\u548c\u6700\u7ec8\u72b6\u6001\u3002\u8fd9\u91cc\u5c55\u793a\u7684\u4e2d\u95f4\u72b6\u6001\u7684\u5206\u5b50\u5e76\u4e0d\u80fd\u6ee1\u8db3\u6211\u4eec\u7684\u9884\u671f\uff0c\u800c\u901a\u8fc7ChatDrug\u5bf9\u8bdd\u5f62\u5f0f\uff0c\u6211\u4eec\u80fd\u5c06\u5176\u8fdb\u4e00\u6b65\u4f18\u5316\u3002<\/span><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">&nbsp;\u2022 ChatDrug \u591a\u80bd\u7f16\u8f91\u5b9a\u6027\u7ed3\u679c\uff1a<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\"><br  \/><\/span><\/section>\n<\/figure>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.3537037037037037\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-5a55c497a4a64391423ee5be5e3aab14.png\"  \/><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.5em;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe 22\uff1aChatDrug\u5728\u591a\u80bd\u7f16\u8f91\u7684\u7ed3\u679c\u3002\u4efb\u52a1\u662f\u5e0c\u671b\u4f18\u5316\u591a\u80bd\u5bf9\u76ee\u6807\u4efb\u52a1\u6709\u66f4\u9ad8\u7684binding affinity\u3002\u8fd9\u91cc\u5c55\u793a\u7684\u662f\u8f93\u5165\u7684\u591a\u80bd\u3001\u4f18\u5316\u7684\u591a\u80bd\u548c\u76ee\u6807\u4efb\u52a1\u5bf9\u5e94\u591a\u80bd\u7684motif\u3002\u8fd9\u91ccmotif\u662f\u7531PWM\u6d4b\u91cf\u3002<\/span><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\"><br  \/><\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 15px;letter-spacing: 0.034em;\">&nbsp;\u2022 ChatDrug \u86cb\u767d\u8d28\u7f16\u8f91\u5b9a\u6027\u7ed3\u679c\uff1a<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<\/figure>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.46574074074074073\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-65c30c5bb9783119118d65172eeefa2b.png\"  \/><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.5em;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe 23\uff1aChatDrug\u5728\u86cb\u767d\u8d28\u4e8c\u7ea7\u7ed3\u6784\u7f16\u8f91\u7684\u7ed3\u679c\u3002\u4efb\u52a1\u662f\u5e0c\u671b\u86cb\u767d\u8d28\u6709\u66f4\u591a\u7684alpha\u6216\u8005beta\u7ed3\u679c\u3002\u5bf9\u5e94\u7684\u6539\u53d8\u90e8\u5206\u90fd\u7528\u84dd\u8272\u5706\u5708\u8fdb\u884c\u4e86\u6807\u8bb0\u3002<\/span><\/p>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<h3 style=\"outline: 0px;letter-spacing: 0.544px;white-space: normal;color: rgb(34, 34, 34);font-family: -apple-system, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);\">\n<section powered-by=\"xiumi.us\" style=\"outline: 0px;letter-spacing: 0.544px;font-family: PingFangSC-light;text-align: right;font-size: 13px;\">\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 10px;outline: 0px;letter-spacing: 0.544px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;text-align: center;\">\n<section style=\"outline: 0px;display: inline-block;vertical-align: middle;\">\n<section style=\"margin-bottom: -2px;outline: 0px;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<section style=\"outline: 0px;clear: both;line-height: 0;\">\n<section style=\"outline: 0px;line-height: 0;width: 0px;\"><svg viewbox=\"0 0 1 1\" style=\"vertical-align:top;\"><\/svg><\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 10px;padding-left: 10px;outline: 0px;border-left: 3px solid rgb(33, 166, 210);border-right: 3px solid rgb(33, 166, 210);border-top-color: rgb(33, 166, 210);border-bottom-color: rgb(33, 166, 210);font-size: 16px;color: rgb(0, 0, 0);line-height: 1.4;\">\n<p style=\"outline: 0px;\"><strong style=\"color: rgb(61, 170, 214);letter-spacing: 0.578px;\"><span style=\"font-size: 15px;\">4&nbsp;\u603b\u7ed3<\/span><\/strong><strong style=\"letter-spacing: 0.544px;outline: 0px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><strong style=\"outline: 0px;text-align: left;color: rgb(33, 166, 210);font-family: PingFangSC-light;letter-spacing: 0.544px;\"><\/strong><\/strong><\/p>\n<\/section>\n<section style=\"margin-top: -2px;outline: 0px;\">\n<section style=\"outline: 0px;float: left;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<section style=\"outline: 0px;float: right;width: 8px;height: 3px;background-color: rgb(33, 166, 210);line-height: 0;\"><br style=\"outline: 0px;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;color: rgb(34, 34, 34);background-color: rgb(255, 255, 255);line-height: 1.75em;\"><span style=\"outline: 0px;color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">&nbsp;<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u6211\u4eec\u901a\u8fc7\u524d\u9762\u4e24\u4e2a\u7cfb\u5217\u4eceML\u6280\u672f\u548cdomain\u89e3\u91ca\u4e24\u4e2a\u89d2\u5ea6\u4ecb\u7ecd\u4e86\u5206\u5b50\u7684\u591a\u6a21\u6001\u4efb\u52a1\u3002\u6b64\u5916\u6211\u4eec\u56e2\u961f\u8fd8\u6709\u4e00\u4e9b\u5176\u4ed6\u7684\u63a2\u7d22\uff0c\u548c\u524d\u9762\u4e24\u4e2a\u7cfb\u5217\u7684\u5de5\u4f5c\u4e00\u8d77\u5728\u4e0b\u56fe\u5c55\u793a\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\"><br  \/><\/span><\/section>\n<figure data-size=\"normal\">\n<section style=\"text-align: center;margin-left: 8px;margin-right: 8px;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"0.47129629629629627\" data-s=\"300,640\"  data-type=\"png\" data-w=\"1080\" style=\"\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-b9384ef1d7600dc6a6db80d60f1d857c.png\"  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">\u56fe 24\uff1a\u6211\u4eec\u56e2\u961f\u5173\u4e8e\u5206\u5b50\u591a\u6a21\u6001\u8868\u793a\u7684\u63a2\u7d22\u3002<\/span><\/section>\n<\/figure>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u6574\u4e2aAI for molecule\/drug discovery\u7684\u53d1\u5c55\u5176\u5b9e\u8fd8\u662f\u6bd4\u8f83\u521d\u6b65\uff0c\u4f46\u662f\u5df2\u7ecf\u5438\u5f15\u5230\u5b66\u672f\u754c\u3001\u5de5\u4e1a\u754c\u7684\u5927\u91cf\u5173\u6ce8\u3002\u56de\u9996\u5341\u5e74\u524d\u6df1\u5ea6\u5b66\u4e60\u521a\u5f00\u59cb\u968f\u7740GPU\u7684\u53d1\u5c55\u5f71\u54cd\u5b66\u672f\u5708\uff0c\u800c\u5341\u5e74\u540e\u7684\u73b0\u5728\u6df1\u5ea6\u5b66\u4e60\u5728\u5b66\u672f\u9886\u57df\u5df2\u7ecf\u53d6\u5f97\u4e86\u975e\u5e38\u5927\u7684\u7a81\u7834\u3002\u6211\u4eec\u56e2\u961f\u4e5f\u662f\u5bf9\u6df1\u5ea6\u5b66\u4e60\u5728\u79d1\u5b66\u9886\u57df\u7684\u524d\u666f\u5f88\u6709\u4fe1\u5fc3\uff0c\u4f46\u8fd9\u4e24\u4e2a\u9886\u57df\u4e4b\u95f4\u76ee\u524d\u4e5f\u5b58\u5728\u7740\u975e\u5e38\u5927\u7684gap\uff1a<\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u5bf9\u4e8edomain\u79d1\u5b66\u5bb6\uff0c\u5f80\u5f80\u628a\u6df1\u5ea6\u5b66\u4e60\u5f53\u505a\u4e00\u4e2a\u53ef\u4ee5\u76f4\u63a5\u4f7f\u7528\u89e3\u51b3\u95ee\u9898\u7684\u9ed1\u76d2\u6a21\u5757\uff0c\u4f46\u662f\u8fd9\u4e2a\u64cd\u4f5c\u5f80\u5f80\u5ffd\u7565\u4e86\u91cd\u8981\u7684\u4f18\u5316\u8fc7\u7a0b\u3002\u8fd9\u4e2a\u53ef\u4ee5\u76f4\u63a5\u901a\u8fc7\u7406\u89e3\u4f18\u5316\u8fc7\u7a0b&nbsp;<\/span><span style=\"font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;color: rgb(136, 136, 136);\">(\u76ee\u524d\u6709\u4e00\u4e9b\u7269\u7406\u7edf\u8ba1\u7684\u5c1d\u8bd5\uff0c\u4f46\u8fd8\u662f\u975e\u5e38\u56f0\u96be)<\/span><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">\uff0c\u6216\u8005\u76ee\u524d\u66f4\u52a0\u53ef\u64cd\u4f5c\u7684\u5c31\u662f\u66f4\u4e25\u683c\u7684\u8ba1\u7b97\u4e0a\u7684\u63a7\u5236\u53d8\u91cf\u5b9e\u9a8c\u3002<\/span><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(63, 63, 63);font-size: 15px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;\">&nbsp;\u2022&nbsp;\u800c\u4eba\u5de5\u667a\u80fd\u9886\u57df\u7684\u79d1\u7814\u5de5\u4f5c\u8005\u5f80\u5f80\u8003\u8651\u4e00\u4e9b\u6bd4\u8f83\u7b80\u5355\u7684\u8bc4\u4f30\u65b9\u6cd5\u548c\u4efb\u52a1\u3002\u8fd9\u4e2a\u5c31\u53ef\u4ee5\u591a\u53bb\u548cdomain\u4e13\u5bb6\u6c9f\u901a\u3001\u7406\u89e3domain\u4e0a\u7684\u95ee\u9898\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(63, 63, 63);\">\u8fd9\u4e9b\u6311\u6218\u662f\u4ea4\u53c9\u9886\u57df\u53d1\u5c55\u7684\u81ea\u7136\u8fc7\u7a0b\uff0c\u4e0b\u9762\u7684\u4e00\u4e2a\u65b9\u5411\u5c31\u9700\u8981\u6570\u5b66\u5bb6\u3001\u7269\u7406\u5b66\u5bb6\u3001\u7edf\u8ba1\u5b66\u5bb6\u3001\u5316\u5b66\u5bb6\u3001\u751f\u7269\u5b66\u5bb6\u3001\u5de5\u7a0b\u5e08\u7b49\u5404\u4e2a\u9886\u57df\/\u6280\u80fd\u7684\u79d1\u7814\u5b66\u8005\u8fdb\u884c\u66f4\u591a\u6df1\u5165\u7684\u4ea4\u6d41\u5408\u4f5c\uff0c\u6784\u9020\u8d77\u4e00\u4e2a\u66f4\u52a0\u4e25\u683c\u7684pipeline\u3002\u4e00\u4e2a\u975e\u5e38\u597d\u7684\u4f8b\u5b50\u5c31\u662fAlphaFold\uff0c\u5b83\u5728\u517c\u987e\u5bf9\u89e3\u51b3folding\u95ee\u9898\u6709\u7a81\u7834\u6027\u8fdb\u5c55\u7684\u540c\u65f6\uff0c\u53c8\u6709\u975e\u5e38\u6df1\u539a\u7684\u6570\u5b66\u7269\u7406\u652f\u6491\uff0c\u5e76\u4e14\u5bf9solvable\u7684\u95ee\u9898\u654f\u9510\u7a0b\u5ea6\u975e\u5e38\u7cbe\u51c6\u3002\u5e0c\u671b\u5c06\u6765\u80fd\u6709\u66f4\u591a\u8fd9\u6837\u7684\u5de5\u4f5c\u51fa\u73b0\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<p style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(61, 170, 214);font-size: 15px;\"><strong>\u53c2\u8003\u6587\u732e<\/strong><\/span><br  \/><\/p>\n<section style=\"margin-left: 8px;margin-right: 8px;text-align: left;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;font-size: 13px;\">[1] GraphMVP:&nbsp;Pre-training Molecular Graph Representation with 3D Geometry, ICLR 2022<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;text-align: left;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;font-size: 13px;\">[2] GeoSSL:&nbsp;Molecular Geometry Pretraining with SE(3)-Invariant Denoising Distance Matching, ICLR 2023<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;text-align: left;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;font-size: 13px;\">[3] MoleculeSDE:&nbsp;A Group Symmetric Stochastic Differential Equation Model for Molecule Multi-modal Pretraining, ICML 2023<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;text-align: left;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">[4] Geom3D:&nbsp;Symmetry-Informed Geometric Representation for Molecules, Proteins, and Crystalline Materials, ArXiv 2023<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;text-align: left;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">[5] GraphCG:&nbsp;Unsupervised Discovery of Steerable Factors in Graphs, NeurIPS Workshop 2022<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;text-align: left;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">[6] MoleculeSTM:&nbsp;Multi-modal Molecule Structure-text Model for Text-based Editing and Retrieval, ArXiv 202<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;text-align: left;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">[7] ProteinDT:&nbsp;A Text-guided Protein Design Framework, ArXiv 2023<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;text-align: left;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">[8] ChatDrug:&nbsp;ChatGPT-powered Conversational Drug Editing Using Retrieval and Domain Feedback, ArXiv 2023<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;text-align: left;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">[9] N-Gram Graph:&nbsp;Simple Unsupervised Representation for Graphs, with Applications to Molecules, NeurIPS 2019<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;text-align: left;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">[10] AWARE:&nbsp;Attentive Walk-Aggregating Graph Neural Networks, TMLR 2022<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;text-align: left;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">[11] SGNN-EBM:&nbsp;Structured Multi-task Learning for Molecular Property Prediction, AISTATS 2022<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;text-align: left;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">[12]&nbsp;GIMLET: A Unified Graph-Text Model for Instruction-Based Molecule Zero-Shot Learning, ArXiv 2023<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;text-align: left;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 13px;\">[13] MolGraphEval:&nbsp;Evaluating Self-Supervised Learning for Molecular Graph Embeddings, ArXiv 2022<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;text-align: left;line-height: normal;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;font-size: 13px;\">[14] D3G:&nbsp;Leveraging Domain Relations for Domain Generalization, ArXiv 2023<\/span><\/section>\n<h2 data-into-catalog-status=\"\" style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/h2>\n<h2 data-into-catalog-status=\"\" style=\"margin-left: 8px;margin-right: 8px;line-height: 1.75em;margin-bottom: 8px;\"><span style=\"color: rgb(136, 136, 136);font-size: 14px;\"><strong>\u81f4\u8c22<\/strong><\/span><\/h2>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"color: rgb(136, 136, 136);font-size: 14px;\">\u8fd9\u4e2a\u535a\u5ba2\u662f\u6211\u5bf9\u4e8e\u8fc7\u53bb\u4e09\u5e74\u534a\u5de5\u4f5c\u7684\u4e00\u4e2a\u7b80\u77ed\u7684\u603b\u7ed3\u3002\u8fd9\u91cc\u4e24\u4e2a\u7cfb\u5217\u4e2d\uff0c\u6700\u65e9\u7684\u5de5\u4f5c\u662fGraphMVP\u548cGeom3D\uff0c\u90fd\u662f21\u5e74\u6691\u5047\u5f00\u59cb\u7684\u5de5\u4f5c\u3002\u975e\u5e38\u611f\u8c22\u5bb6\u4eba\u670b\u53cb\u3001\u5404\u4f4d\u6307\u5bfc\u8001\u5e08\u548c\u5408\u4f5c\u8005\u7684\u5927\u529b\u652f\u6301\u3002Chapter 2\u662f\u6211\u4e3b\u8981\u5728Mila Ph.D.\u671f\u95f4\u5b8c\u6210\u7684\u5de5\u4f5c\uff0c\u975e\u5e38\u611f\u8c22\u5510\u5efa\u6559\u6388\u7684\u6307\u5bfc\u3002Chapter 3\u4e3b\u8981\u662f\u6211\u5728Caltech &amp; Nvidia Prof. Anima Anandkumar\u6307\u5bfc\u4e0b\u5b8c\u6210\uff0c\u5979\u7684\u6307\u5bfc\u975e\u5e38\u6709\u8fdc\u89c1\u3002\u6b64\u5916\u4e5f\u975e\u5e38\u611f\u8c22\u52a0\u62ff\u5927\u56fd\u5bb6\u5b9e\u9a8c\u5ba4\u7684Prof. Hongyu Guo\u8fd8\u6709UC Berkeley\u7684Prof. Omar Yaghi, Prof. Christian Borgs, Prof. Jennifer Chayes\u7684\u652f\u6301\u3002<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/section>\n<blockquote class=\"js_blockquote_wrap\" data-type=\"2\" data-url=\"\" data-author-name=\"\" data-content-utf8-length=\"48\" data-source-title=\"\" data-text=\"\u672c\u6587\u9996\u53d1\u4e8e\u4f5c\u8005\u77e5\u4e4e\uff1ahttps:\/\/zhuanlan.zhihu.com\/p\/639560302\" data-editid=\"pra49a5wzg9s9g5uyo\">\n<section class=\"js_blockquote_digest\">\n<section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: left;\"><span style=\"color: rgb(136, 136, 136);font-size: 14px;\">\u672c\u6587\u9996\u53d1\u4e8e\u4f5c\u8005\u77e5\u4e4e\uff1a<\/span><\/section>\n<section style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: left;\"><span style=\"color: rgb(136, 136, 136);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.034em;font-size: 14px;\">https:\/\/zhuanlan.zhihu.com\/p\/639560302<\/span><\/section>\n<\/section>\n<\/section>\n<\/blockquote>\n<p style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 14px;\"><\/span><\/p>\n<p style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 14px;\">\u6b22\u8fce\u626b\u7801\u8fdb\u5165\u300c\u96c6\u667a\u6591\u56fe\u300d\uff0c\u9605\u8bfb\u6536\u85cf\u5b8c\u6574\u8def\u5f84\u6587\u7ae0<\/span><\/p>\n<p style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;line-height: 1.75em;text-align: center;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"1\" data-s=\"300,640\"  data-type=\"png\" data-w=\"400\" style=\"width: 160px;\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-44bd7d0be6c0d75948c2f1f7732a7565.png\"  \/><\/p>\n<p style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;line-height: 1.75em;text-align: center;\"><span style=\"color: rgb(136, 136, 136);font-size: 14px;\">\u6591\u56fe\u5730\u5740\uff1ahttps:\/\/pattern.swarma.org\/article\/242<\/span><\/p>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;color: rgb(34, 34, 34);background-color: rgb(255, 255, 255);line-height: 1.75em;\"><br  \/><\/section>\n<p style=\"margin-bottom: 0px;clear: none;color: rgb(63, 63, 63);font-family: PingFangSC-light;font-size: 13px;letter-spacing: 0.544px;text-wrap: wrap;outline: 0px;line-height: 2em;visibility: visible;\"><strong style=\"outline: 0px;letter-spacing: 0.578px;text-indent: 0em;font-size: 15px;visibility: visible;\"><span style=\"outline: 0px;font-size: 13px;letter-spacing: 0.544px;text-decoration-style: solid;text-decoration-color: rgb(63, 63, 63);visibility: visible;\"><br  \/><\/span><\/strong><\/p>\n<h2 data-into-catalog-status=\"\" style=\"margin-right: 8px;margin-bottom: 8px;margin-left: 8px;letter-spacing: 0.578px;text-wrap: wrap;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(61, 170, 214);\"><strong>\u4f5c\u8005\u7b80\u4ecb<\/strong><\/span><\/h2>\n<p style=\"margin-right: 8px;margin-left: 8px;outline: 0px;font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;color: rgb(34, 34, 34);background-color: rgb(255, 255, 255);line-height: 1.75em;margin-bottom: 8px;\"><strong><span style=\"font-size: 14px;letter-spacing: 0.544px;text-indent: 0em;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(63, 63, 63);\">\u5218\u5723\u8d85<\/span><\/strong><span style=\"font-size: 14px;letter-spacing: 0.544px;text-indent: 0em;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(63, 63, 63);\">\uff0c Mila \u7b2c\u56db\u5e74\u535a\u58eb\uff0c\u5bfc\u5e08\u662f\u5510\u5efa\u6559\u6388\u3002\u5c06\u4e8e2023\u5e74\u79cb\u5b63\u52a0\u5165UC Berkeley\u548cCaltech\u8054\u5408\u535a\u540e\uff0c\u5bfc\u5e08\u662fProf. Jennifer Chayes, Prof. Christian Borgs, \u548c Prof. Anima Anandkumar\u3002<\/span><span style=\"color: rgb(63, 63, 63);font-size: 14px;letter-spacing: 0.544px;text-indent: 0em;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">\u79d1\u7814\u65b9\u5411\uff1a\u8fc1\u79fb\u5b66\u4e60(\u591a\u4efb\u52a1\u3001\u9884\u8bad\u7ec3)\uff0c\u591a\u6a21\u6001\u5b66\u4e60\uff0c\u7edf\u8ba1\u751f\u6210\u5b66\u4e60\u3002<span style=\"color: rgb(63, 63, 63);letter-spacing: 0.544px;text-wrap: wrap;background-color: rgb(255, 255, 255);\">\u4e2a\u4eba\u4e3b\u9875\uff1ahttps:\/\/chao1224.github.io<\/span><\/span><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;text-align: center;\"><br  \/><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"margin-left: 8px;margin-right: 8px;margin-bottom: 0px;line-height: 1.75em;\"><span style=\"font-size: 14px;color: rgb(136, 136, 136);letter-spacing: 0.544px;text-wrap: wrap;background-color: rgb(255, 255, 255);\">\u5728\u96c6\u667a\u4ff1\u4e50\u90e8\u300c<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247666274&amp;idx=1&amp;sn=87f83deb79cad313ae4deb8f17badff6&amp;chksm=e89910efdfee99f98566e612d3aff638f0dead89fd2ecabef048f7efebedda6c56faf4fe7920&amp;scene=21#wechat_redirect\" textvalue=\"\u56fe\u795e\u7ecf\u7f51\u7edc\u4e0e\u7ec4\u5408\u4f18\u5316\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener noreferrer\">\u56fe\u795e\u7ecf\u7f51\u7edc\u4e0e\u7ec4\u5408\u4f18\u5316<\/a>\u300d\u8bfb\u4e66\u4f1a\u7b2c\u4e8c\u671f\uff0c\u4e2d\u56fd\u4eba\u6c11\u5927\u5b66\u9ad8\u74f4\u4eba\u5de5\u667a\u80fd\u5b66\u9662\u52a9\u7406\u6559\u6388\u9ec4\u6587\u70b3\u4ecb\u7ecd\u4e86\u51e0\u4f55<span style=\"letter-spacing: 0.544px;background-color: rgb(255, 255, 255);\">\u56fe\u795e\u7ecf\u7f51\u7edc\u5e94\u7528\u4e8e\u5206\u5b50\u8868\u793a\u5b66\u4e60\u7684\u76f8\u5173\u7814\u7a76\u3002\u6b22\u8fce\u611f\u5174\u8da3\u7684\u670b\u53cb\u62a5\u540d\u53c2\u4e0e\uff1a<\/span><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages wxw-img\" data-galleryid=\"\" data-ratio=\"1\" data-s=\"300,640\"  data-type=\"png\" data-w=\"400\" style=\"width: 142px;height: auto !important;\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-186b39d69ba6a8ea609d891a6db26608.png\"  \/><\/p>\n<p style=\"text-align: center;\"><span style=\"background-color: rgb(255, 255, 255);color: rgb(136, 136, 136);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;letter-spacing: 0.544px;text-align: justify;\">\u8bfb\u4e66\u4f1a\u5730\u5740\uff1ahttps:\/\/pattern.swarma.org\/study_group_issue\/485<\/span><\/p>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);\"><br  \/><\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-top: 10px;margin-bottom: 0px;text-wrap: wrap;outline: 0px;letter-spacing: 0.544px;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);text-align: center;justify-content: center;\">\n<section style=\"outline: 0px;display: inline-block;width: auto;vertical-align: top;min-width: 10%;height: auto;box-shadow: rgb(0, 0, 0) 0px 0px 0px;border-bottom: 9px solid rgb(169, 215, 227);border-bottom-right-radius: 0px;\">\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: -15px;outline: 0px;\">\n<section style=\"padding-right: 10px;padding-left: 10px;outline: 0px;color: rgb(12, 130, 169);font-size: 16px;line-height: 2;letter-spacing: 3px;\">\n<p style=\"outline: 0px;\"><strong style=\"outline: 0px;\">\u56fe\u795e\u7ecf\u7f51\u7edc\u4e0e\u7ec4\u5408\u4f18\u5316\u8bfb\u4e66\u4f1a\u8fdb\u884c\u4e2d<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 0px;text-wrap: wrap;outline: 0px;letter-spacing: 0.544px;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);\">\n<p style=\"outline: 0px;\"><br style=\"outline: 0px;color: rgb(63, 63, 63);font-family: PingFangSC-light;font-size: 15px;letter-spacing: 0.544px;\"  \/><\/p>\n<\/section>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;text-wrap: wrap;outline: 0px;clear: both;min-height: 1em;letter-spacing: 0.544px;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);line-height: 2em;\"><span style=\"font-size: 15px;letter-spacing: 0.544px;text-indent: 0em;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">\u73b0\u5b9e\u4e16\u754c\u4e2d\u5927\u91cf\u95ee\u9898\u7684\u89e3\u51b3\u4f9d\u8d56\u4e8e\u7b97\u6cd5\u7684\u8bbe\u8ba1\u4e0e\u6c42\u89e3\u3002\u4f20\u7edf\u7b97\u6cd5\u7531\u4eba\u7c7b\u4e13\u5bb6\u8bbe\u8ba1\uff0c\u800c\u968f\u7740\u4eba\u5de5\u667a\u80fd\u6280\u672f\u4e0d\u65ad\u53d1\u5c55\uff0c\u7b97\u6cd5\u81ea\u52a8\u5b66\u4e60\u7b97\u6cd5\u7684\u6848\u4f8b\u65e5\u76ca\u589e\u591a\uff0c\u5982\u4ee5\u795e\u7ecf\u7f51\u7edc\u4e3a\u4ee3\u8868\u7684\u7684\u4eba\u5de5\u667a\u80fd\u7b97\u6cd5\uff0c\u8fd9\u662f\u7b97\u6cd5\u795e\u7ecf\u5316\u6c42\u89e3\u7684\u7f18\u7531\u3002\u5728\u7b97\u6cd5\u795e\u7ecf\u5316\u6c42\u89e3\u65b9\u5411\u4e0a\uff0c\u56fe\u795e\u7ecf\u7f51\u7edc\u662f\u4e00\u4e2a\u5f3a\u6709\u529b\u7684\u5de5\u5177\uff0c\u80fd\u591f\u5145\u5206\u5229\u7528\u56fe\u7ed3\u6784\u7684\u7279\u6027\uff0c\u5b9e\u73b0\u5bf9\u9ad8\u590d\u6742\u5ea6\u7b97\u6cd5\u7684\u9ad8\u6548\u8fd1\u4f3c\u6c42\u89e3\u3002\u57fa\u4e8e\u56fe\u795e\u7ecf\u7f51\u7edc\u7684\u590d\u6742\u7cfb\u7edf\u4f18\u5316\u4e0e\u63a7\u5236\u5c06\u4f1a\u662f\u5927\u6a21\u578b\u70ed\u6f6e\u4e4b\u540e\u65b0\u7684\u672a\u6765\u65b9\u5411\u3002<\/span><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;text-wrap: wrap;outline: 0px;clear: both;min-height: 1em;letter-spacing: 0.544px;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);line-height: 2em;\"><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 15px;letter-spacing: 0.544px;text-indent: 0em;\"><br  \/><\/span><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;text-wrap: wrap;outline: 0px;clear: both;min-height: 1em;letter-spacing: 0.544px;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);line-height: 2em;\"><span style=\"font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 15px;letter-spacing: 0.544px;text-indent: 0em;\">\u4e3a\u4e86\u63a2\u8ba8\u56fe\u795e\u7ecf\u7f51\u7edc\u5728\u7b97\u6cd5\u795e\u7ecf\u5316\u6c42\u89e3\u7684\u53d1\u5c55\u4e0e\u73b0\u5b9e\u5e94\u7528\uff0c\u96c6\u667a\u4ff1\u4e50\u90e8\u8054\u5408\u56fd\u9632\u79d1\u6280\u5927\u5b66\u7cfb\u7edf\u5de5\u7a0b\u5b66\u9662\u526f\u6559\u6388\u8303\u957f\u4fca\u3001\u4e2d\u56fd\u4eba\u6c11\u5927\u5b66\u9ad8\u74f4\u4eba\u5de5\u667a\u80fd\u5b66\u9662\u52a9\u7406\u6559\u6388\u9ec4\u6587\u70b3\uff0c\u5171\u540c\u53d1\u8d77\u300c\u56fe\u795e\u7ecf\u7f51\u7edc\u4e0e\u7ec4\u5408\u4f18\u5316\u300d\u8bfb\u4e66\u4f1a\u3002\u8bfb\u4e66\u4f1a\u5c06\u805a\u7126\u4e8e\u56fe\u795e\u7ecf\u7f51\u7edc\u4e0e\u7b97\u6cd5\u795e\u7ecf\u5316\u6c42\u89e3\u7684\u76f8\u5173\u9886\u57df\uff0c\u5305\u62ec\u795e\u7ecf\u7b97\u6cd5\u63a8\u7406\u3001\u7ec4\u5408\u4f18\u5316\u95ee\u9898\u6c42\u89e3\u3001\u51e0\u4f55\u56fe\u795e\u7ecf\u7f51\u7edc\uff0c\u4ee5\u53ca\u7b97\u6cd5\u795e\u7ecf\u5316\u6c42\u89e3\u5728 AI for Science \u4e2d\u7684\u5e94\u7528\u7b49\u65b9\u9762\uff0c\u5e0c\u671b\u4e3a\u53c2\u4e0e\u8005\u63d0\u4f9b\u4e00\u4e2a\u5b66\u672f\u4ea4\u6d41\u5e73\u53f0\uff0c\u6fc0\u53d1\u53c2\u4e0e\u8005\u7684\u5b66\u672f\u5174\u8da3\uff0c\u8fdb\u4e00\u6b65\u63a8\u52a8\u76f8\u5173\u9886\u57df\u7684\u7814\u7a76\u548c\u5e94\u7528\u53d1\u5c55\u3002\u8bfb\u4e66\u4f1a\u4ece2023\u5e746\u670814\u65e5\u5f00\u59cb\uff0c\u6bcf\u5468\u4e09\u665a 19:00-21:00 \u4e3e\u884c\uff0c\u6301\u7eed\u65f6\u95f4\u9884\u8ba18\u5468\u3002\u6b22\u8fce\u611f\u5174\u8da3\u7684\u670b\u53cb\u62a5\u540d\u53c2\u4e0e\uff01<\/span><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;letter-spacing: 0.578px;text-indent: 0em;text-wrap: wrap;line-height: 2em;\"><span style=\"color: rgb(136, 136, 136);font-size: 15px;letter-spacing: 0.544px;text-decoration-style: solid;text-decoration-color: rgb(136, 136, 136);\"><br  \/><\/span><\/section>\n<section style=\"margin-right: 8px;margin-left: 8px;letter-spacing: 0.578px;text-wrap: wrap;text-align: justify;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247663464&amp;idx=1&amp;sn=073e3d7c6d0ac643a93d01a7fd4d624f&amp;chksm=e89925e5dfeeacf3b350427aaf66812d11f458381944a2ada8a4ed19921ccc29a88708504490&amp;scene=21#wechat_redirect\" textvalue=\"\u4f60\u5df2\u9009\u4e2d\u4e86\u6dfb\u52a0\u94fe\u63a5\u7684\u5185\u5bb9\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"1\" rel=\"noopener noreferrer\"><span class=\"js_jump_icon h5_image_link\"><img class=\"rich_pages wxw-img\" data-backh=\"239\" data-backw=\"562\" data-cropselx1=\"0\" data-cropselx2=\"562\" data-cropsely1=\"0\" data-cropsely2=\"224\" data-galleryid=\"\" data-ratio=\"0.4255555555555556\" data-s=\"300,640\"  data-type=\"png\" data-w=\"900\" style=\"width: 562px;height: auto !important;\" src=\"\/wp-content\/uploads\/2023\/07\/wxsync-2023-07-ef76ed97042640607fa28adb73e9fec7.png\"  \/><\/span><\/a><span style=\"background-color: rgb(255, 255, 255);color: rgb(63, 63, 63);font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 15px;letter-spacing: 0.544px;text-indent: 0em;text-align: justify;\">\u8be6\u60c5\u8bf7\u89c1\uff1a<\/span><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247663464&amp;idx=1&amp;sn=073e3d7c6d0ac643a93d01a7fd4d624f&amp;chksm=e89925e5dfeeacf3b350427aaf66812d11f458381944a2ada8a4ed19921ccc29a88708504490&amp;scene=21#wechat_redirect\" textvalue=\"\u52a0\u901f\u7ecf\u5178\u7b97\u6cd5\u6548\u7387\uff0c\u7a81\u7834\u73b0\u5b9e\u6280\u672f\u74f6\u9888\uff1a\u56fe\u795e\u7ecf\u7f51\u7edc\u4e0e\u7ec4\u5408\u4f18\u5316\u8bfb\u4e66\u4f1a\u542f\u52a8\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" 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SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);text-align: center;justify-content: center;\">\n<section style=\"outline: 0px;display: inline-block;width: auto;vertical-align: top;min-width: 10%;height: auto;box-shadow: rgb(0, 0, 0) 0px 0px 0px;border-bottom: 9px solid rgb(169, 215, 227);border-bottom-right-radius: 0px;\">\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: -15px;outline: 0px;\">\n<section style=\"padding-right: 10px;padding-left: 10px;outline: 0px;color: rgb(12, 130, 169);font-size: 16px;line-height: 2;letter-spacing: 3px;\">\n<p style=\"outline: 0px;\"><strong style=\"outline: 0px;\">AI+Science \u8bfb\u4e66\u4f1a<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 0px;outline: 0px;letter-spacing: 0.544px;text-wrap: wrap;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);\">\n<p style=\"outline: 0px;\"><br style=\"outline: 0px;\"  \/><\/p>\n<\/section>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;letter-spacing: 0.544px;text-wrap: wrap;clear: both;min-height: 1em;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);line-height: 2em;\"><span style=\"outline: 0px;font-size: 15px;letter-spacing: 0.544px;text-indent: 0em;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">AI+Science \u662f\u8fd1\u5e74\u5174\u8d77\u7684\u5c06\u4eba\u5de5\u667a\u80fd\u548c\u79d1\u5b66\u76f8\u7ed3\u5408\u7684\u4e00\u79cd\u8d8b\u52bf\u3002\u4e00\u65b9\u9762\u662f AI for Science\uff0c\u673a\u5668\u5b66\u4e60\u548c\u5176\u4ed6 AI \u6280\u672f\u53ef\u4ee5\u7528\u6765\u89e3\u51b3\u79d1\u5b66\u7814\u7a76\u4e2d\u7684\u95ee\u9898\uff0c\u4ece\u9884\u6d4b\u5929\u6c14\u548c\u86cb\u767d\u8d28\u7ed3\u6784\uff0c\u5230\u6a21\u62df\u661f\u7cfb\u78b0\u649e\u3001\u8bbe\u8ba1\u4f18\u5316\u6838\u805a\u53d8\u53cd\u5e94\u5806\uff0c\u751a\u81f3\u50cf\u79d1\u5b66\u5bb6\u4e00\u6837\u8fdb\u884c\u79d1\u5b66\u53d1\u73b0\uff0c\u88ab\u79f0\u4e3a\u79d1\u5b66\u53d1\u73b0\u7684\u201c\u7b2c\u4e94\u8303\u5f0f\u201d\u3002\u53e6\u4e00\u65b9\u9762\u662f Science for AI\uff0c\u79d1\u5b66\u5c24\u5176\u662f\u7269\u7406\u5b66\u4e2d\u7684\u89c4\u5f8b\u548c\u601d\u60f3\u542f\u53d1\u673a\u5668\u5b66\u4e60\u7406\u8bba\uff0c\u4e3a\u4eba\u5de5\u667a\u80fd\u7684\u53d1\u5c55\u63d0\u4f9b\u5168\u65b0\u7684\u89c6\u89d2\u548c\u65b9\u6cd5\u3002<\/span><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;letter-spacing: 0.544px;text-wrap: wrap;clear: both;min-height: 1em;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);line-height: 2em;\"><br  \/><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;letter-spacing: 0.544px;text-wrap: wrap;clear: both;min-height: 1em;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);line-height: 2em;\"><span style=\"outline: 0px;text-indent: 0em;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 15px;letter-spacing: 0.544px;\">\u96c6\u667a\u4ff1\u4e50\u90e8\u8054\u5408\u65af\u5766\u798f\u5927\u5b66\u8ba1\u7b97\u673a\u79d1\u5b66\u7cfb\u535a\u58eb\u540e\u7814\u7a76\u5458\u5434\u6cf0\u9716\uff08Jure Leskovec \u6559\u6388\u6307\u5bfc\uff09\u3001\u54c8\u4f5b\u91cf\u5b50\u8ba1\u5212\u7814\u7a76\u5458\u6248\u9e3f\u4e1a\u3001\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u7269\u7406\u7cfb\u535a\u58eb\u751f\u5218\u5b50\u9e23\uff08Max Tegmark \u6559\u6388\u6307\u5bfc\uff09\uff0c\u5171\u540c\u53d1\u8d77\u4ee5<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247659349&amp;idx=1&amp;sn=5e0bcad718d122a04e1b34a8bf94f906&amp;chksm=e89935d8dfeebcceb72a61c9c7602a6042eefad7bf106147d81c3110e04c6f61fbde5214aec9&amp;scene=21#wechat_redirect\" textvalue=\"\u201cAI+Science\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" style=\"color: var(--weui-LINK);outline: 0px;cursor: pointer;\" rel=\"noopener noreferrer\">\u201cAI+Science<\/a>\u201d\u4e3a\u4e3b\u9898\u7684\u8bfb\u4e66\u4f1a\uff0c\u63a2\u8ba8\u8be5\u9886\u57df\u7684\u91cd\u8981\u95ee\u9898\uff0c\u5171\u5b66\u5171\u7814\u76f8\u5173\u6587\u732e\u3002\u6b22\u8fce\u5bf9\u63a2\u7d22\u8fd9\u4e2a\u6fc0\u52a8\u4eba\u5fc3\u7684\u524d\u6cbf\u9886\u57df\u6709\u5174\u8da3\u7684\u670b\u53cb\u62a5\u540d\u53c2\u4e0e\u3002<\/span><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;letter-spacing: 0.544px;text-wrap: wrap;clear: both;min-height: 1em;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);line-height: 2em;\"><br  \/><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;letter-spacing: 0.544px;text-wrap: wrap;clear: both;min-height: 1em;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);line-height: 2em;text-align: center;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247659349&amp;idx=1&amp;sn=5e0bcad718d122a04e1b34a8bf94f906&amp;chksm=e89935d8dfeebcceb72a61c9c7602a6042eefad7bf106147d81c3110e04c6f61fbde5214aec9&amp;scene=21#wechat_redirect\" textvalue=\"\u4f60\u5df2\u9009\u4e2d\u4e86\u6dfb\u52a0\u94fe\u63a5\u7684\u5185\u5bb9\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"1\" hasload=\"1\" rel=\"noopener noreferrer\"><span style=\"text-indent: 0em;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 15px;letter-spacing: 0.544px;outline: 0px;line-height: 0;vertical-align: bottom;user-select: none;\"><span class=\"js_jump_icon h5_image_link\"><img class=\"rich_pages wxw-img\" data-ratio=\"0.562962962962963\"  data-w=\"1080\" style=\"outline: 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15px;letter-spacing: 0.544px;\">\u8be6\u60c5\u8bf7\u89c1\uff1a<\/span><br  \/><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;letter-spacing: 0.544px;text-wrap: wrap;clear: both;min-height: 1em;color: rgb(136, 136, 136);font-size: 14px;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;background-color: rgb(255, 255, 255);line-height: 2em;\"><span style=\"outline: 0px;color: rgb(63, 63, 63);font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;font-size: 15px;text-decoration: underline;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247659349&amp;idx=1&amp;sn=5e0bcad718d122a04e1b34a8bf94f906&amp;chksm=e89935d8dfeebcceb72a61c9c7602a6042eefad7bf106147d81c3110e04c6f61fbde5214aec9&amp;scene=21#wechat_redirect\" textvalue=\"\u4eba\u5de5\u667a\u80fd\u548c\u79d1\u5b66\u53d1\u73b0\u76f8\u4e92\u8d4b\u80fd\u7684\u65b0\u8303\u5f0f\uff1aAI+Science \u8bfb\u4e66\u4f1a\u542f\u52a8\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"color: var(--weui-LINK);outline: 0px;cursor: pointer;\" rel=\"noopener noreferrer\">\u4eba\u5de5\u667a\u80fd\u548c\u79d1\u5b66\u53d1\u73b0\u76f8\u4e92\u8d4b\u80fd\u7684\u65b0\u8303\u5f0f\uff1aAI+Science \u8bfb\u4e66\u4f1a\u542f\u52a8<\/a><\/span><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;text-wrap: wrap;background-color: rgb(255, 255, 255);\"><br style=\"letter-spacing: 0.544px;\"  \/><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 0px;margin-left: 8px;outline: 0px;font-family: system-ui, -apple-system, &quot;system-ui&quot;, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);\"><br  \/><\/section>\n<section powered-by=\"xiumi.us\" style=\"margin-bottom: 0px;outline: 0px;letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;background-color: rgb(255, 255, 255);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">\n<p style=\"margin-right: 8px;margin-bottom: 5px;margin-left: 8px;outline: 0px;letter-spacing: 0.544px;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;color: rgb(0, 0, 0);font-size: 16px;text-align: center;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><strong style=\"outline: 0px;text-align: left;color: rgb(33, 166, 210);font-family: PingFangSC-light;letter-spacing: 0.544px;\"><span style=\"outline: 0px;font-size: 15px;letter-spacing: 0.544px;\">\u63a8\u8350\u9605\u8bfb<\/span><\/strong><\/strong><\/p>\n<section style=\"margin-right: 8px;margin-bottom: 8px;margin-left: 8px;outline: 0px;letter-spacing: 0.544px;\"><strong style=\"outline: 0px;\">1.&nbsp;<\/strong><span style=\"text-decoration: underline;\"><strong style=\"outline: 0px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247666274&amp;idx=1&amp;sn=87f83deb79cad313ae4deb8f17badff6&amp;chksm=e89910efdfee99f98566e612d3aff638f0dead89fd2ecabef048f7efebedda6c56faf4fe7920&amp;scene=21#wechat_redirect\" textvalue=\"\u51e0\u4f55\u56fe\u795e\u7ecf\u7f51\u7edc\u53ca\u5176\u79d1\u5b66\u5e94\u7528\u4e28\u56fe\u795e\u7ecf\u7f51\u7edc\u4e0e\u7ec4\u5408\u4f18\u5316\u8bfb\u4e66\u4f1a\u00b7\u5468\u4e09\u76f4\u64ad\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener noreferrer\">\u51e0\u4f55\u56fe\u795e\u7ecf\u7f51\u7edc\u53ca\u5176\u79d1\u5b66\u5e94\u7528\u4e28\u56fe\u795e\u7ecf\u7f51\u7edc\u4e0e\u7ec4\u5408\u4f18\u5316\u8bfb\u4e66\u4f1a<\/a><\/strong><\/span><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247497413&amp;idx=1&amp;sn=486b179ed3f344950574656672c61042&amp;chksm=e897ac48dfe0255e2ac60fbf16b3ef1478341e5f0985582dc40f9bc022238c32ad0611bb1814&amp;scene=21#wechat_redirect\" textvalue=\"Science\u7ecf\u5178\u7efc\u8ff0\u6587\u7ae0\uff1a\u4ec0\u4e48\u662f\u79d1\u5b66\u5b66\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"outline: 0px;color: var(--weui-LINK);text-decoration: underline;cursor: pointer;letter-spacing: 0.544px;\" rel=\"noopener noreferrer\"><\/a><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 8px;margin-left: 8px;outline: 0px;letter-spacing: 0.544px;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;\">2.<\/strong><span style=\"outline: 0px;letter-spacing: 0.544px;text-decoration: underline;\"><strong style=\"outline: 0px;\">&nbsp;<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247560989&amp;idx=3&amp;sn=1981e3b53fdb1c8b854432e15e00ab18&amp;chksm=e896b590dfe13c86049895c162e8d7c2ff393e289c82dcbaa68c84e4c372a17c9bfe0e396b12&amp;scene=21#wechat_redirect\" textvalue=\"\u625b\u9f0e\u4e4b\u4f5c\uff01Twitter \u56fe\u673a\u5668\u5b66\u4e60\u5927\u725b\u53d1\u8868160\u9875\u8bba\u6587\uff1a\u4ee5\u51e0\u4f55\u5b66\u89c6\u89d2\u7edf\u4e00\u6df1\u5ea6\u5b66\u4e60\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener noreferrer\"><\/a><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247666190&amp;idx=2&amp;sn=47f59f4b3bf20aa81af7784cdbc05d1b&amp;chksm=e8991083dfee9995d95c4e30bf7b5b0bc1a4c1bfae91ce1442427d2a1b83194a1dc9d95fe288&amp;scene=21#wechat_redirect\" textvalue=\"AI for \u79d1\u5b66\u6a21\u62df\uff1a\u5206\u5b50\u52a8\u529b\u5b66\u4e0e\u5206\u5b50\u6a21\u62df\u4e28\u5468\u65e5\u76f4\u64ad\u00b7 AI+Science \u8bfb\u4e66\u4f1a\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" style=\"text-decoration: underline;font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;letter-spacing: 0.544px;text-wrap: wrap;background-color: rgb(255, 255, 255);\" rel=\"noopener noreferrer\"><strong>AI for \u79d1\u5b66\u6a21\u62df\uff1a\u5206\u5b50\u52a8\u529b\u5b66\u4e0e\u5206\u5b50\u6a21\u62df\u4e28AI+Science \u8bfb\u4e66\u4f1a<\/strong><\/a><\/strong><\/span><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 8px;margin-left: 8px;outline: 0px;letter-spacing: 0.544px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247497413&amp;idx=1&amp;sn=486b179ed3f344950574656672c61042&amp;chksm=e897ac48dfe0255e2ac60fbf16b3ef1478341e5f0985582dc40f9bc022238c32ad0611bb1814&amp;scene=21#wechat_redirect\" textvalue=\"Science\u7ecf\u5178\u7efc\u8ff0\u6587\u7ae0\uff1a\u4ec0\u4e48\u662f\u79d1\u5b66\u5b66\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"outline: 0px;color: var(--weui-LINK);text-decoration: underline;cursor: pointer;\" rel=\"noopener noreferrer\"><\/a><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 8px;margin-left: 8px;outline: 0px;letter-spacing: 0.544px;\"><strong style=\"outline: 0px;\">3.<\/strong>&nbsp;<span style=\"text-decoration: underline;\"><strong style=\"color: rgb(136, 136, 136);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;letter-spacing: 0.544px;text-wrap: wrap;background-color: rgb(255, 255, 255);outline: 0px;\"><a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247560989&amp;idx=3&amp;sn=1981e3b53fdb1c8b854432e15e00ab18&amp;chksm=e896b590dfe13c86049895c162e8d7c2ff393e289c82dcbaa68c84e4c372a17c9bfe0e396b12&amp;scene=21#wechat_redirect\" textvalue=\"\u625b\u9f0e\u4e4b\u4f5c\uff01Twitter \u56fe\u673a\u5668\u5b66\u4e60\u5927\u725b\u53d1\u8868160\u9875\u8bba\u6587\uff1a\u4ee5\u51e0\u4f55\u5b66\u89c6\u89d2\u7edf\u4e00\u6df1\u5ea6\u5b66\u4e60\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" rel=\"noopener noreferrer\">\u625b\u9f0e\u4e4b\u4f5c\uff01Twitter \u56fe\u673a\u5668\u5b66\u4e60\u5927\u725b\u53d1\u8868160\u9875\u8bba\u6587\uff1a\u4ee5\u51e0\u4f55\u5b66\u89c6\u89d2\u7edf\u4e00\u6df1\u5ea6\u5b66\u4e60<\/a><\/strong><\/span><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 8px;margin-left: 8px;outline: 0px;letter-spacing: 0.544px;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;\">4.&nbsp;<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247576923&amp;idx=2&amp;sn=57f0d320812c01ff6f5ea97c09fc9623&amp;chksm=e896f7d6dfe17ec038e8d238dae313119fca8c62aabd4730896bc99398db981dd5d9d3e0b927&amp;scene=21#wechat_redirect\" textvalue=\"\u300a\u5f20\u6c5f\u00b7\u590d\u6742\u79d1\u5b66\u524d\u6cbf27\u8bb2\u300b\u5b8c\u6574\u4e0a\u7ebf\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"outline: 0px;color: var(--weui-LINK);text-decoration: underline;cursor: pointer;letter-spacing: 0.544px;\" rel=\"noopener noreferrer\"><strong style=\"outline: 0px;\">\u300a\u5f20\u6c5f\u00b7\u590d\u6742\u79d1\u5b66\u524d\u6cbf27\u8bb2\u300b\u5b8c\u6574\u4e0a\u7ebf\uff01<\/strong><\/a><\/strong><\/strong><\/strong><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 8px;margin-left: 8px;outline: 0px;letter-spacing: 0.544px;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;\">5.&nbsp;<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247617062&amp;idx=1&amp;sn=e963acb6885ea3b26d32e91c12eae076&amp;chksm=e89650abdfe1d9bddf82c71e612a15bc4393d0a61cde39d325b01b3099247145c98b492c37b8&amp;scene=21#wechat_redirect\" textvalue=\"\u6210\u4e3a\u96c6\u667aVIP\uff0c\u89e3\u9501\u200d\u5168\u7ad9\u8bfe\u7a0b\uff0f\u8bfb\u4e66\u4f1a\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"outline: 0px;color: var(--weui-LINK);cursor: pointer;letter-spacing: 0.544px;\" rel=\"noopener noreferrer\"><strong style=\"outline: 0px;\"><span style=\"outline: 0px;letter-spacing: 0.544px;text-decoration: underline;\">\u6210\u4e3a\u96c6\u667aVIP\uff0c\u89e3\u9501\u5168\u7ad9\u8bfe\u7a0b\uff0f\u8bfb\u4e66\u4f1a<\/span><\/strong><\/a><\/strong><\/strong><\/strong><\/strong><\/section>\n<section style=\"margin-right: 8px;margin-bottom: 10px;margin-left: 8px;outline: 0px;letter-spacing: 0.544px;\"><strong style=\"outline: 0px;\">6<strong style=\"outline: 0px;letter-spacing: 0.544px;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;\">.&nbsp;<a target=\"_blank\" href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMjQyNzQ5MA==&amp;mid=2247615893&amp;idx=2&amp;sn=96bad22819460c3b17f165fef8817c89&amp;chksm=e8965f18dfe1d60e531b3a749cfdfade06962791e3f1b100872d24e032b6b3130a6ead599060&amp;scene=21#wechat_redirect\" textvalue=\"\u52a0\u5165\u96c6\u667a\uff0c\u200d\u4e00\u8d77\u590d\u6742\uff01\" linktype=\"text\" imgurl=\"\" imgdata=\"null\" data-itemshowtype=\"0\" tab=\"innerlink\" data-linktype=\"2\" hasload=\"1\" style=\"outline: 0px;color: var(--weui-LINK);text-decoration: underline;cursor: pointer;letter-spacing: 0.544px;\" rel=\"noopener noreferrer\"><strong style=\"outline: 0px;\">\u52a0\u5165\u96c6\u667a\uff0c\u4e00\u8d77\u590d\u6742\uff01<\/strong><\/a><\/strong><\/strong><\/strong><\/section>\n<p style=\"margin-right: 8px;margin-bottom: 5px;margin-left: 8px;outline: 0px;\"><br  \/><\/p>\n<\/section>\n<section style=\"margin-bottom: 0px;outline: currentcolor none 0px;letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;background-color: rgb(255, 255, 255);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;font-size: 15px;text-align: left;color: rgb(255, 255, 255);font-family: PingFangSC-light;\">\u70b9\u51fb\u201c\u9605\u8bfb\u539f\u6587\u201d\uff0c\u62a5\u540d\u8bfb\u4e66\u4f1a<\/strong><\/section>\n<section style=\"margin-bottom: 0px;outline: currentcolor none 0px;letter-spacing: 0.544px;white-space: normal;color: rgb(136, 136, 136);font-size: 14px;background-color: rgb(255, 255, 255);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\"><span style=\"background-color: rgb(0, 122, 170);font-size: 15px;\"><strong style=\"outline: 0px;letter-spacing: 0.544px;font-size: 15px;text-align: left;color: rgb(255, 255, 255);font-family: PingFangSC-light;\">\u70b9\u51fb\u201c\u9605\u8bfb\u539f\u6587\u201d\uff0c\u62a5\u540d\u8bfb\u4e66\u4f1a<\/strong><\/span><\/section>\n<p style=\"display: none;\"><mp-style-type data-value=\"3\"><\/mp-style-type><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5bfc\u8bed \u5728\u8ba1\u7b97\u751f\u7269\u3001\u5316\u5b66\u3001\u6750\u6599\u9886\u57df\uff0c\u4f34\u968f\u7740\u6df1\u5ea6\u5b66\u4e60\u7684\u5e7f\u6cdb\u4f7f\u7528\uff0c\u5206\u5b50\u8868\u5f81&nbsp; (representation) \u5df2\u7ecf\u6210\u4e3a\u6700\u57fa\u7840\u7684\u7814\u7a76\u95ee\u9898\u3002\u6765\u81ea\u52a0\u62ff\u5927 MILA \u7814\u7a76\u6240\u7684\u5218\u5723\u8d85\u535a\u58eb\u6240\u5728\u56e2\u961f\u81f4\u529b\u4e8e\u5c0f\u5206\u5b50\u8868\u5f81\u7814\u7a76\uff0c\u5c0f\u5206\u5b50\u8868\u5f81\u4e2d\u5305\u542b\u6709\u4e30\u5bcc\u7684\u591a\u6a21\u6001\u4fe1\u606f\u3002\u672c\u6587\u4e3b\u8981\u4ece\u4e24\u4e2a\u65b9\u9762\u5bf9\u4ed6\u535a\u58eb\u671f\u95f4\u7684\u5de5\u4f5c\u505a\u4e86\u7b80\u77ed\u603b\u7ed3\uff1a\u51e0&#8230;<\/p>\n","protected":false},"author":0,"featured_media":43567,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"special":[],"_links":{"self":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/43604"}],"collection":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=43604"}],"version-history":[{"count":0,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/43604\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/media\/43567"}],"wp:attachment":[{"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=43604"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=43604"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=43604"},{"taxonomy":"special","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fspecial&post=43604"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}