{"id":43948,"date":"2023-07-25T21:39:16","date_gmt":"2023-07-25T13:39:16","guid":{"rendered":"https:\/\/swarma.org\/?p=43948"},"modified":"2023-07-25T21:39:16","modified_gmt":"2023-07-25T13:39:16","slug":"nat-mach-intell-%e9%80%9f%e9%80%92%ef%bc%9a%e8%b6%85%e5%9b%be%e5%9b%a0%e5%ad%90%e5%88%86%e8%a7%a3%e6%96%b9%e6%b3%95%e7%94%a8%e4%ba%8e%e5%a4%9a%e7%bb%84%e7%bb%87%e5%9f%ba%e5%9b%a0%e8%a1%a8%e8%be%be","status":"publish","type":"post","link":"https:\/\/swarma.org\/?p=43948","title":{"rendered":"Nat. Mach. Intell. \u901f\u9012\uff1a\u8d85\u56fe\u56e0\u5b50\u5206\u89e3\u65b9\u6cd5\u7528\u4e8e\u591a\u7ec4\u7ec7\u57fa\u56e0\u8868\u8fbe\u63d2\u8865"},"content":{"rendered":"
\n
\n
\n
\n

<\/p>\n


<\/strong><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/strong><\/strong><\/span><\/p>\n

\u5173\u952e\u8bcd\uff1a\u591a\u7ec4\u7ec7\u57fa\u56e0\u8868\u8fbe\u63d2\u8865\uff0c\u8f6c\u5f55\u7ec4\u5b66\uff0c\u8d85\u56fe\uff0c\u56fe\u8868\u793a\u5b66\u4e60\uff0c\u6ce8\u610f\u529b\u673a\u5236\uff0c\u7f16\u7801\u5668-\u89e3\u7801\u5668<\/span><\/strong><\/strong><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/strong><\/strong><\/span><\/p>\n


<\/p>\n<\/section>\n

\n
\n
\n
<\/svg><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
<\/section>\n<\/section>\n
\n


<\/p>\n

<\/p>\n<\/section>\n

\n
\n
\n
\n
\u8bba\u6587\u9898\u76ee\uff1a<\/span>Hypergraph factorization for multi-tissue gene expression imputation<\/span>
<\/section>\n
\u6591\u56fe\u5730\u5740\uff1ahttps:\/\/pattern.swarma.org\/paper\/dd285798-24f5-11ee-931d-0242ac17000d<\/span><\/section>\n
\u8bba\u6587\u5730\u5740\uff1ahttps:\/\/www.nature.com\/articles\/s42256-023-00684-8<\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/blockquote>\n

<\/section>\n
\u591a\u7ec4\u7ec7\u63d2\u8865<\/span>\uff08Multi-tissue imputation\uff09<\/span>\u662f\u8f6c\u5f55\u7ec4\u5b66\u7684\u6838\u5fc3\u6280\u672f\u4e4b\u4e00\uff0c\u7528\u4e8e\u5904\u7406\u5728\u591a\u7ec4\u7ec7\u57fa\u56e0\u8868\u8fbe\u6570\u636e\u4e2d\u7684\u7f3a\u5931\u503c\uff0c\u8fdb\u800c\u5e2e\u52a9\u9610\u660e\u8c03\u8282\u5404\u79cd\u53d1\u80b2\u548c\u751f\u7406\u8fc7\u7a0b\u7684\u673a\u5236\u3002\u63d2\u8865\u7b97\u6cd5\u5229\u7528\u5176\u4ed6\u76f8\u5173\u7ec4\u7ec7\u7684\u4fe1\u606f\u6765\u9884\u6d4b\u7f3a\u5931\u7684\u57fa\u56e0\u8868\u8fbe\u503c\u3002\u4f8b\u5982\uff0c\u5982\u679c\u809d\u810f\u7ec4\u7ec7\u7684\u57fa\u56e0\u8868\u8fbe\u6570\u636e\u4e2d\u6709\u7f3a\u5931\u503c\uff0c\u53ef\u4ee5\u4f7f\u7528\u6765\u81ea\u80f0\u817a\u6216\u80be\u810f\u7b49\u76f8\u5173\u7ec4\u7ec7\u7684\u6570\u636e\u6765\u9884\u6d4b\u8fd9\u4e9b\u7f3a\u5931\u503c\u3002\u9488\u5bf9\u57fa\u56e0\u8868\u8fbe\u7684\u63d2\u8865\u7b97\u6cd5\uff0c\u901a\u5e38\u6d89\u53ca\u5230\u7edf\u8ba1\u6a21\u578b\u6216\u673a\u5668\u5b66\u4e60\u7b97\u6cd5\uff0c\u4ece\u5df2\u77e5\u6570\u636e\u4e2d\u5b66\u4e60\u57fa\u56e0\u8868\u8fbe\u6a21\u5f0f\uff0c\u5e76\u9884\u6d4b\u7f3a\u5931\u6570\u636e\u3002\u4f46\u5728\u8ba1\u7b97\u4e0a\uff0c\u591a\u7ec4\u7ec7\u8f6c\u5f55\u7ec4\u63d2\u8865\u5177\u6709\u6311\u6218\u6027\uff0c\u56e0\u4e3a\u6570\u636e\u7ef4\u5ea6\u968f\u7740\u57fa\u56e0\u548c\u7ec4\u7ec7\u7684\u89c4\u6a21\u53d8\u5316\u800c\u5feb\u901f\u53d8\u5316\uff0c\u901a\u5e38\u5bfc\u81f4\u6a21\u578b\u8fc7\u53c2\u6570\u5316\u3002<\/span><\/section>\n

<\/span><\/section>\n
\u6700\u65b0\u53d1\u8868\u5728 Nature Machine Intelligence<\/em> \u7684\u8bba\u6587\u4e2d\uff0c\u4f5c\u8005\u63d0\u51fa\u4e86\u4e00\u79cd\u56fe\u8868\u793a\u5b66\u4e60\u65b9\u6cd5<\/strong>\u2014\u2014HYFA\uff08\u8d85\u56fe\u56e0\u5b50\u5206\u89e3\uff0chypergraph factorization\uff09<\/strong>\uff0c\u7528\u4e8e\u540c\u65f6\u5904\u7406\u6765\u81ea\u591a\u4e2a\u7ec4\u7ec7\u548c\u591a\u79cd\u7ec6\u80de\u7c7b\u578b\u7684\u57fa\u56e0\u8868\u8fbe\u6570\u636e\uff0c\u5e76\u9884\u6d4b\u5176\u4e2d\u7684\u7f3a\u5931\u503c\u3002\u8be5\u65b9\u6cd5\u5728\u5904\u7406\u5927\u89c4\u6a21\u57fa\u56e0\u8868\u8fbe\u6570\u636e\u65f6\uff0c\u5177\u6709\u8f83\u9ad8\u7684\u8ba1\u7b97\u6548\u7387\u548c\u51c6\u786e\u6027\u3002<\/span><\/section>\n

<\/span><\/section>\n
\u5177\u4f53\u800c\u8a00\uff0c\u5728HYFA\u4e2d\uff0c\u591a\u7ec4\u7ec7\u57fa\u56e0\u8868\u8fbe\u88ab\u8868\u793a\u4e3a\u4e00\u4e2a\u7531\u4e2a\u4f53<\/span>\uff08\u5373\u57fa\u56e0\u6d4b\u5e8f\u751f\u7269\u4e2a\u4f53\uff09<\/span>\u3001\u5143\u57fa\u56e0<\/span>\uff08\u5373\u4e00\u7ec4\u6216\u4e00\u7c7b\u57fa\u56e0\u7684\u96c6\u5408\uff09<\/span>\u548c\u7ec4\u7ec7<\/span>\uff08\u5373\u57fa\u56e0\u8868\u8fbe\u6570\u636e\u7684\u6765\u6e90\u90e8\u4f4d\uff09<\/span>\u6784\u6210\u7684\u8d85\u56fe\u3002\u5176\u4e2d\u6bcf\u4e2a\u8282\u70b9\u4ee3\u8868\u4e00\u4e2a\u5143\u57fa\u56e0\uff0c\u6bcf\u4e2a\u8d85\u8fb9<\/span>\uff08hyperedge\uff09<\/span>\u8fde\u63a5\u5230\u4e00\u7ec4\u5143\u57fa\u56e0\u8282\u70b9\uff0c\u4ee3\u8868\u4e86\u4e00\u4e2a\u4e2a\u4f53\u5728\u7279\u5b9a\u7ec4\u7ec7\u4e2d\u8868\u8fbe\u7684\u57fa\u56e0\u96c6\u5408\u3002\u4f7f\u7528\u8d85\u56fe\u6570\u636e\u7ed3\u6784\u53ef\u4ee5\u6355\u6349\u5230\u57fa\u56e0\u8868\u8fbe\u6570\u636e\u4e2d\u7684\u590d\u6742\u6a21\u5f0f\uff0c\u5305\u62ec\u57fa\u56e0\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u3001\u57fa\u56e0\u5728\u4e0d\u540c\u7ec4\u7ec7\u4e2d\u7684\u8868\u8fbe\u5dee\u5f02\uff0c\u4ee5\u53ca\u4e0d\u540c\u4e2a\u4f53\u4e4b\u95f4\u7684\u5dee\u5f02\uff0c\u8fdb\u800c\u4e3a\u673a\u5668\u5b66\u4e60\u63d0\u4f9b\u4e30\u5bcc\u4e0a\u4e0b\u6587\u4fe1\u606f\u3002<\/span><\/section>\n
HYFA\u67b6\u6784\u7684\u5173\u952e\u90e8\u5206\u662f\u8d85\u56fe\u6d88\u606f\u4f20\u9012\u7684\u795e\u7ecf\u7f51\u7edc\uff0c\u91c7\u7528\u6ce8\u610f\u529b\u673a\u5236\uff0c\u5bf9\u4e0d\u540c\u8d85\u8fb9\u8d4b\u4e88\u4e0d\u540c\u6743\u91cd\uff0c\u7136\u540e\u6839\u636e\u6743\u91cd\u5bf9\u8d85\u8fb9\u8fdb\u884c\u805a\u5408\uff0c\u4ece\u800c\u5f97\u5230\u6bcf\u4e2a\u8282\u70b9\u7684\u65b0\u7684\u7279\u5f81\u8868\u793a\u3002\u8fd9\u79cd\u673a\u5236\u5e2e\u52a9\u6a21\u578b\u786e\u5b9a\u54ea\u4e9b\u4fe1\u606f\u66f4\u91cd\u8981<\/span>\uff08\u6ce8\u610f\u529b\u6743\u91cd\u53cd\u6620\u4e86\u67d0\u4e2a\u8282\u70b9\u5bf9\u5176\u4ed6\u8282\u70b9\u7684\u91cd\u8981\u6027\uff09<\/span>\uff0c\u4ece\u800c\u7f13\u89e3\u8fc7\u5ea6\u538b\u7f29\u95ee\u9898\uff0c\u5e76\u589e\u5f3a\u53ef\u89e3\u91ca\u6027\u3002<\/span><\/section>\n

<\/span><\/section>\n
HYFA\u7684\u53e6\u4e00\u4e2a\u91cd\u8981\u7279\u6027\u662f\u5b83\u5e76\u4e0d\u4f9d\u8d56\u4e8e\u5177\u4f53\u57fa\u56e0\u578b\uff0c\u800c\u662f\u4f9d\u8d56\u4e8e\u57fa\u56e0\u8868\u8fbe\u7684\u6a21\u5f0f\u548c\u7ec4\u7ec7\u7684\u7c7b\u578b\uff0c\u56e0\u6b64\u53ef\u4ee5\u652f\u6301\u6bcf\u4e2a\u4e2a\u4f53\u6536\u96c6\u7684\u4e0d\u540c\u7684\u7ec4\u7ec7\u6570\u91cf\uff0c\u5e76\u4e14\u53ef\u4ee5\u5229\u7528\u7ec4\u7ec7\u548c\u57fa\u56e0\u7684\u5171\u4eab\u8c03\u63a7\u7ed3\u6784<\/span>\uff08\u5373\u57fa\u56e0\/\u7ec4\u7ec7\/\u4e2a\u4f53\u5173\u7cfb\u7684\u5148\u9a8c\u77e5\u8bc6\u6216\u5047\u8bbe\uff09<\/span>\uff0c\u6709\u6548\u5730\u8fdb\u884c\u57fa\u56e0\u8868\u8fbe\u63d2\u8865\u3002<\/span><\/section>\n

<\/span><\/section>\n
HYFA\u6a21\u578b\u8fd8\u5305\u62ec\u4e00\u4e2a\u7f16\u7801\u5668\u548c\u4e00\u4e2a\u89e3\u7801\u5668\uff0c\u7f16\u7801\u5668\u8d1f\u8d23\u5c06\u8f93\u5165\u6570\u636e\u8f6c\u6362\u4e3a\u4f4e\u7ef4\u9690\u7a7a\u95f4\uff0c\u89e3\u7801\u5668\u5219\u5c06\u9690\u7a7a\u95f4\u6570\u636e\u8f6c\u6362\u56de\u539f\u59cb\u9ad8\u7ef4\u7a7a\u95f4\uff0c\u4fbf\u4e8e\u6a21\u578b\u5904\u7406\u9ad8\u7ef4\u6570\u636e\u3002<\/span><\/section>\n

<\/span><\/section>\n
\u5b9e\u9a8c\u548c\u5206\u6790\u8868\u660e\uff0c\u8be5\u65b9\u6cd5\u662f\u53c2\u6570\u9ad8\u6548\u7684\uff0c\u65e0\u9700\u5927\u91cf\u53c2\u6570\uff0c\u53ef\u4ee5\u5728\u8f83\u5c11\u7684\u6570\u636e\u4e0a\u8fdb\u884c\u6709\u6548\u5b66\u4e60\u3002HYFA\u5728\u5904\u7406\u57fa\u56e0\u8868\u8fbe\u6570\u636e\u65f6\uff0c\u4e0d\u9700\u8981\u83b7\u53d6\u4e2a\u4f53\u7684\u57fa\u56e0\u578b\u4fe1\u606f\uff0c\u540c\u65f6\u53ef\u4ee5\u5e94\u5bf9\u6570\u636e\u4e2d\u6bcf\u4e2a\u4e2a\u4f53\u6536\u96c6\u7684\u7ec4\u7ec7\u6570\u91cf\u4e0d\u540c\u7684\u60c5\u51b5\uff0c\u56e0\u6b64\u5728\u5b9e\u9645\u5e94\u7528\u4e2d\u66f4\u52a0\u7075\u6d3b\u3002\u4f7f\u7528HYFA\u63d2\u8865\u7684\u6570\u636e\u96c6\uff0c\u7814\u7a76\u4eba\u5458\u53ef\u4ee5\u66f4\u6709\u6548\u5730\u8bc6\u522b\u5f71\u54cd\u57fa\u56e0\u8868\u8fbe\u9057\u4f20\u4f4d\u70b9\u7684\u9057\u4f20\u53d8\u5f02\u3002<\/span><\/section>\n

<\/span><\/section>\n
\u6b64\u5916\uff0cHYFA\u4e0d\u4ec5\u53ef\u4ee5\u7528\u4e8e\u5355\u4e2a\u6570\u636e\u96c6\u7684\u57fa\u56e0\u8868\u8fbe\u63d2\u8865\uff0c\u8fd8\u53ef\u4ee5\u7528\u4e8e\u6574\u5408\u591a\u4e2a\u7ec4\u7ec7\u548c\/\u6216\u7ec6\u80de\u7c7b\u578b\u7684\u8f6c\u5f55\u7ec4\u6570\u636e\uff0c\u8fd9\u6709\u52a9\u4e8e\u6784\u5efa\u548c\u5229\u7528\u5927\u89c4\u6a21\u7684\u8f6c\u5f55\u7ec4\u751f\u7269\u5e93\u3002<\/span><\/section>\n

<\/span><\/section>\n
<\/em><\/section>\n

\u56fe 1 \u672c\u6587 HYFA \u6a21\u578b\u67b6\u6784\u793a\u610f\u56fe\u3002\u5176\u4e2d a\u4e3aHYFA\u7684\u8d85\u56fe\u7ed3\u6784\uff0cb \u4e3a\u6a21\u578b\u7684\u6ce8\u610f\u529b\u673a\u5236\uff0cc \u4e3a\u7f16\u7801-\u89e3\u7801\u8fc7\u7a0b\u3002<\/span><\/p>\n


<\/section>\n
\n

<\/span><\/section>\n
\u7f16\u8bd1\uff5c\u5218\u57f9\u6e90<\/span><\/section>\n

<\/section>\n
\n
\n
\n
\n

\u56fe\u795e\u7ecf\u7f51\u7edc\u4e0e\u7ec4\u5408\u4f18\u5316\u8bfb\u4e66\u4f1a\u8fdb\u884c\u4e2d<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


<\/section>\n
<\/span><\/a><\/section>\n
<\/span><\/section>\n
\u8be6\u60c5\u8bf7\u89c1\uff1a<\/span><\/span><\/section>\n
\u52a0\u901f\u7ecf\u5178\u7b97\u6cd5\u6548\u7387\uff0c\u7a81\u7834\u73b0\u5b9e\u6280\u672f\u74f6\u9888\uff1a\u56fe\u795e\u7ecf\u7f51\u7edc\u4e0e\u7ec4\u5408\u4f18\u5316\u8bfb\u4e66\u4f1a\u542f\u52a8<\/a><\/span>
<\/span><\/section>\n


<\/p>\n


<\/section>\n

\u63a8\u8350\u9605\u8bfb<\/span><\/strong><\/strong><\/p>\n

\u200d<\/span>1. <\/strong>\u56fe\u8868\u793a\u5b66\u4e60\u3001\u9884\u6d4b\u548c\u8bc4\u4f30 | Nat. Comput. Sci. \u901f\u9012<\/a><\/strong><\/span><\/strong><\/strong><\/section>\n
2.<\/strong> Sci. Adv. \u901f\u9012\uff1a\u5927\u578b\u8d85\u56fe\u4e2d\u7684\u793e\u56e2\u68c0\u6d4b<\/a><\/strong><\/span><\/strong><\/section>\n
3. <\/strong><\/strong>\u524d\u6cbf\u8fdb\u5c55\uff1a\u968f\u673a\u8d85\u56fe\u4e0a\u7ea7\u8054\u6545\u969c\u7684\u9608\u503c\u6a21\u578b<\/a><\/strong><\/strong><\/span><\/strong><\/strong><\/section>\n
4. <\/strong><\/strong><\/span>\u5f20\u6c5f\uff1a\u7b2c\u4e09\u4ee3\u4eba\u5de5\u667a\u80fd\u6280\u672f\u57fa\u7840\u2014\u2014\u4ece\u53ef\u5fae\u5206\u7f16\u7a0b\u5230\u56e0\u679c\u63a8\u7406 | \u96c6\u667a\u5b66\u56ed\u5168\u65b0\u8bfe\u7a0b<\/a><\/strong><\/strong><\/span><\/section>\n
5. \u300a\u5f20\u6c5f\u00b7\u590d\u6742\u79d1\u5b66\u524d\u6cbf27\u8bb2\u300b\u5b8c\u6574\u4e0a\u7ebf\uff01<\/strong><\/a><\/strong><\/strong><\/strong><\/section>\n
6. <\/strong><\/strong>\u52a0\u5165\u96c6\u667a\u5b66\u56edVIP\uff0c\u83b7\u5f9720\u5468\u5e74\u201c\u6d8c\u73b0\u201d\u5b66\u672f\u5e74\u4f1a\u5165\u573a\u5238\uff01<\/a><\/strong><\/strong><\/strong><\/strong><\/span><\/section>\n
7. <\/strong>\u52a0\u5165\u96c6\u667a\uff0c\u4e00\u8d77\u590d\u6742\uff01<\/strong><\/span><\/a><\/section>\n

<\/section>\n

<\/section>\n
\u70b9\u51fb\u201c\u9605\u8bfb\u539f\u6587\u201d\uff0c\u62a5\u540d\u8bfb\u4e66\u4f1a<\/strong><\/strong><\/span><\/strong><\/section>\n

<\/mp-style-type><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u5173\u952e\u8bcd\uff1a\u591a\u7ec4\u7ec7\u57fa\u56e0\u8868\u8fbe\u63d2\u8865\uff0c\u8f6c\u5f55\u7ec4\u5b66\uff0c\u8d85\u56fe\uff0c\u56fe\u8868\u793a\u5b66\u4e60\uff0c\u6ce8\u610f\u529b\u673a\u5236\uff0c\u7f16\u7801\u5668-\u89e3\u7801\u5668 \u8bba\u6587\u9898\u76ee\uff1aHypergraph factorization for multi-tissue gene expression imputation \u6591\u56fe\u5730\u5740\uff1ahttps:\/\/pattern.swarma.org\/pa…<\/p>\n","protected":false},"author":0,"featured_media":43944,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"special":[],"_links":{"self":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/43948"}],"collection":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=43948"}],"version-history":[{"count":0,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/43948\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/media\/43944"}],"wp:attachment":[{"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=43948"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=43948"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=43948"},{"taxonomy":"special","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fspecial&post=43948"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}