{"id":45340,"date":"2023-09-21T22:00:16","date_gmt":"2023-09-21T14:00:16","guid":{"rendered":"https:\/\/swarma.org\/?p=45340"},"modified":"2023-09-21T22:00:16","modified_gmt":"2023-09-21T14:00:16","slug":"%e7%bb%86%e8%83%9e%e6%80%8e%e6%a0%b7%e6%8f%90%e9%80%9f%e6%8d%a2%e6%8c%a1%ef%bc%9f%e6%96%b0%e7%a0%94%e7%a9%b6%e6%8f%ad%e7%a4%ba%e7%bb%86%e8%83%9e%e8%bf%81%e7%a7%bb%e7%9a%84%e5%a4%9a%e5%b0%ba%e5%ba%a6","status":"publish","type":"post","link":"https:\/\/swarma.org\/?p=45340","title":{"rendered":"\u7ec6\u80de\u600e\u6837\u63d0\u901f\u6362\u6321\uff1f\u65b0\u7814\u7a76\u63ed\u793a\u7ec6\u80de\u8fc1\u79fb\u7684\u591a\u5c3a\u5ea6\u6d8c\u73b0\u4e0e\u8c03\u63a7\u673a\u5236"},"content":{"rendered":"
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\u5317\u4eac\u5e08\u8303\u5927\u5b66\u7cfb\u7edf\u79d1\u5b66\u5b66\u9662\/\u975e\u5e73\u8861\u7cfb\u7edf\u7814\u7a76\u6240\u674e\u8f89\u6559\u6388\u7814\u7a76\u7ec4\u957f\u671f\u5f00\u5c55\u751f\u7269\u590d\u6742\u7cfb\u7edf\u7684\u52a8\u529b\u5b66\u7814\u7a76\uff0c\u53d1\u5c55\u4e86\u6d3b\u7ec6\u80de\u4e09\u7ef4\u5355\u5206\u5b50\u52a8\u6001\u6210\u50cf\u6280\u672f\u548c\u5b9a\u91cf\u5206\u6790\u65b9\u6cd5 <\/span>[STAR Protocols 3, 101790 (2022)]<\/span>\uff0c\u63a2\u7a76\u4e86\u7ec6\u80de\u5185\u7684\u8f93\u8fd0\u52a8\u529b\u5b66\u4ee5\u53ca\u7ec6\u80de\u8fc1\u79fb\u7684\u76f8\u5173\u751f\u7269\u7269\u7406\u95ee\u9898<\/span> [JACS 137, 436 (2015)\uff1bPNAS 115, 12118 (2018)\uff1bCPL(Express Letters) 37, 078701(2020); PNAS 118, e2022422118 (2021); iScience 25, 104210 (2022); Small 18, 2106498 (2022)]<\/span>\u3002<\/span><\/p>\n


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\u76f8\u5173\u6210\u679c\u4ee5\u201cSwitch of cell migration modes orchestrated by changes of three-dimensional lamellipodium structure and intracellular diffusion\u201d\u4e3a\u9898\u53d1\u8868\u5728 Nature Communications 14, 5166,<\/span> (2023)<\/span>\u3002\u8be5\u6587\u7ae0\u88ab\u7f16\u8f91\u63a8\u8350\u5e76\u6536\u5f55\u4e8e\u591a\u5c3a\u5ea6\u751f\u7269\u590d\u6742\u7cfb\u7edf\u7814\u7a76\u4e13\u9898\u201cFrom molecules and cells to organisms\u201d<\/span> (\u8be6\u89c1https:\/\/www.nature.com\/collections\/bbcaeejggj)<\/span>\u3002\u8be5\u5de5\u4f5c\u83b7\u5f97\u4e86\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u548c\u4e2d\u56fd\u79d1\u5b66\u9662\u7684\u652f\u6301\u3002<\/span><\/p>\n


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\u6587<\/span>\u7ae0\u4fe1\u606f\uff1a<\/span>Chao Jiang, Hong-Yu Luo, Xinpeng Xu, Shuo-Xing Dou, Wei Li, Dongshi Guan, Fangfu Ye, Xiaosong Chen, Ming Guo, Peng-Ye Wang & Hui Li. Switch of cell migration modes orchestrated by changes of three-dimensional lamellipodium structure and intracellular diffusion. Nature Commun. 14, 5166 (2023).<\/span><\/p>\n

\u6587\u7ae0\u94fe\u63a5\uff1ahttps:\/\/www.nature.com\/articles\/s41467-023-40858-x<\/span><\/p>\n<\/section>\n<\/section>\n<\/blockquote>\n

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\u56fe1. \u89d2\u8d28\u7ec6\u80de\u7684\u8fc1\u79fb\u901f\u5ea6\u4e0e\u5185\u90e8\u91cf\u5b50\u70b9\u7684\u6269\u6563\u901f\u5ea6\u6b63\u76f8\u5173\u3002<\/span><\/o:p><\/p>\n

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\u56fe2. \u53d1\u73b0\u65b0\u7684\u7ec6\u80de\u6162\u901f\u8fc1\u79fb\u6a21\u5f0f\u3002\u4e0e\u4f20\u7edf\u7684\u7ec6\u80de\u5feb\u901f\u8fc1\u79fb\u6a21\u5f0f\u4e0d\u540c\uff0c\u5728\u6162\u901f\u8fc1\u79fb\u7ec6\u80de\u4e2d\u3002\u5176\u677f\u72b6\u4f2a\u8db3\u524d\u9ad8\u540e\u4f4e\u3001\u80de\u5185\u6269\u6563\u901f\u5ea6\u964d\u4f4e\uff0c\u751f\u7269\u5927\u5206\u5b50\u5c40\u9650\u4e8e\u4f2a\u8db3\u524d\u7aef\u3002<\/span><\/o:p><\/section>\n
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\u56fe3. \u7ec6\u80de\u8f6c\u5411\u8fc7\u7a0b\u4e2d\u7684\u80de\u5185\u6269\u6563\u548c\u4f2a\u8db3\u4e09\u7ef4\u7ed3\u6784\u51fa\u73b0\u5de6\u53f3\u5bf9\u79f0\u6027\u7834\u7f3a\uff1a\u5904\u4e8e\u8f6c\u5411\u5916\u4fa7\u7684\u4f2a\u8db3\u53d8\u539a\u4e14\u5185\u90e8\u6269\u6563\u901f\u5ea6\u4e0b\u964d\u3002<\/span><\/section>\n


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\u56fe4. \u7ec6\u80de\u8fc1\u79fb\u6a21\u5f0f\u8f6c\u6362\u7684\u751f\u7269\u7269\u7406\u673a\u5236\u3002<\/span><\/p>\n


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\u751f\u547d\u590d\u6742\u6027\u7cfb\u5217\u8bfb\u4e66\u4f1a<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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\u751f\u547d\u662f\u4ec0\u4e48\uff1f\u751f\u547d\u600e\u6837\u8d77\u6e90\uff1f\u751f\u547d\u600e\u6837\u6f14\u5316\uff1f\u8fd9\u4e9b\u662f\u5bf9\u751f\u547d\u73b0\u8c61\u7684\u672c\u8d28\u8ffd\u95ee\uff0c\u9664\u4e86\u4f20\u7edf\u7684\u751f\u7269\u5b66\u7814\u7a76\uff0c\u5982\u4eca\u6709\u5927\u91cf\u6765\u81ea\u4fe1\u606f\u3001\u7269\u7406\u3001\u8ba1\u7b97\u673a\u9886\u57df\u7684\u5de5\u5177\u65b9\u6cd5\uff0c\u6b63\u5728\u63ed\u5f00\u751f\u547d\u590d\u6742\u6027\u8c1c\u9898\u3002<\/span>\u57fa\u4e8e\u6b64\uff0c\u96c6\u667a\u4ff1\u4e50\u90e8\u7b56\u5212\u201c\u751f\u547d\u590d\u6742\u6027\u201d\u7cfb\u5217\u8bfb\u4e66\u4f1a\uff0c\u81ea2020\u5e7411\u67085\u65e5\u81f3\u4eca\uff0c\u8fd1\u767e\u540d\u5728\u4ece\u4e8b\u76f8\u5173\u95ee\u9898\u7814\u7a76\u7684\u8001\u5e08\u540c\u5b66\u6216\u611f\u5174\u8da3\u7684\u670b\u53cb\u53c2\u4e0e\u3002<\/span><\/span><\/p>\n


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\u4e86\u89e3\u8bfb\u4e66\u4f1a\u5177\u4f53\u89c4\u5219\u3001\u62a5\u540d\u8bfb\u4e66\u4f1a\u8bf7\u70b9\u51fb\u4e0b\u65b9\u6587\u7ae0\uff1a<\/span><\/p>\n

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\u63a8\u8350\u9605\u8bfb<\/span><\/strong><\/strong><\/p>\n

1. <\/strong> Nat.Commun.\u901f\u9012\uff1a\u79bb\u4f53\u795e\u7ecf\u7ec6\u80de\u7f51\u7edc\u201c\u6253\u4e52\u4e53\u7403\u201d\u65f6\u7684\u4e34\u754c\u52a8\u529b\u5b66<\/a><\/strong><\/span><\/strong><\/section>\n
2.<\/strong>  \u4ece\u7ec6\u80de\u5230\u89e3\u5256\u7a33\u6001\u7684\u6269\u5c55\uff1a\u4ece\u4e2a\u4f53\u53d1\u80b2\u5230\u96c6\u4f53\u667a\u80fd<\/a><\/strong><\/span><\/section>\n
3.  <\/strong><\/strong>\u7ec6\u83cc\u5982\u4f55\u51b3\u5b9a\u4f55\u65f6\u5206\u88c2\uff1f\u968f\u673a\u8fc7\u7a0b\u89c6\u89d2\u4e0b\u7684\u7ec6\u83cc\u7ec6\u80de\u5206\u88c2\u8c03\u63a7<\/a><\/strong><\/strong><\/span><\/strong><\/strong><\/section>\n
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4. <\/strong><\/span>\u5f20\u6c5f\uff1a\u7b2c\u4e09\u4ee3\u4eba\u5de5\u667a\u80fd\u6280\u672f\u57fa\u7840\u2014\u2014\u4ece\u53ef\u5fae\u5206\u7f16\u7a0b\u5230\u56e0\u679c\u63a8\u7406 | \u96c6\u667a\u5b66\u56ed\u5168\u65b0\u8bfe\u7a0b<\/a><\/strong><\/strong><\/span><\/section>\n
5. <\/strong>\u6210\u4e3a\u96c6\u667aVIP\uff0c\u89e3\u9501\u5168\u7ad9\u8bfe\u7a0b\uff0f\u8bfb\u4e66\u4f1a<\/a><\/span><\/strong><\/section>\n
6. <\/strong>\u52a0\u5165\u96c6\u667a\uff0c\u4e00\u8d77\u590d\u6742\uff01<\/strong><\/span><\/a><\/section>\n


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\u70b9\u51fb\u201c\u9605\u8bfb\u539f\u6587\u201d\uff0c\u62a5\u540d\u8bfb\u4e66\u4f1a<\/span><\/strong><\/span><\/p>\n

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\u5bfc\u8bed \u5317\u4eac\u5e08\u8303\u5927\u5b66\u7cfb\u7edf\u79d1\u5b66\u5b66\u9662\/\u975e\u5e73\u8861\u7cfb\u7edf\u7814\u7a76\u6240\u674e\u8f89\u6559\u6388\u7814\u7a76\u7ec4\u957f\u671f\u5f00\u5c55\u751f\u7269\u590d\u6742\u7cfb\u7edf\u7684\u52a8\u529b\u5b66\u7814\u7a76\uff0c\u63a2\u7a76\u7ec6\u80de\u5185\u7684\u8f93\u8fd0\u52a8\u529b\u5b66\u4ee5\u53ca\u7ec6\u80de\u8fc1\u79fb\u7684\u76f8\u5173\u751f\u7269\u7269\u7406\u95ee\u9898\u3002\u8fd1\u65e5\u8be5\u8bfe\u9898\u7ec4\u5728 Nature Communications \u53d1\u8868\u6700\u65b0\u6210\u679c\uff0c\u53d1\u73b0\u7ec6\u80de\u80fd\u591f\u5728\u5feb\u6162\u4e24\u79cd\u8fc1\u79fb\u6a21\u5f0f\u4e4b\u95f4\u52a8\u6001\u53ef\u9006\u7684\u8f6c\u6362\uff0c\u8c03\u8282\u7ec6\u80de\u7684\u901f\u5ea6\u548c\u65b9\u5411\uff0c\u5bf9\u5916…<\/p>\n","protected":false},"author":0,"featured_media":45333,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"special":[],"_links":{"self":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/45340"}],"collection":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=45340"}],"version-history":[{"count":0,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/45340\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/media\/45333"}],"wp:attachment":[{"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=45340"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=45340"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=45340"},{"taxonomy":"special","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fspecial&post=45340"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}