{"id":46431,"date":"2023-11-10T17:05:09","date_gmt":"2023-11-10T09:05:09","guid":{"rendered":"https:\/\/swarma.org\/?p=46431"},"modified":"2023-11-10T17:05:09","modified_gmt":"2023-11-10T09:05:09","slug":"%e5%9f%ba%e7%a1%80%e6%a8%a1%e5%9e%8b%e5%9c%a8%e8%b0%83%e6%8e%a7%e5%9f%ba%e5%9b%a0%e7%bb%84%e5%ad%a6%e5%92%8crna%e7%a7%91%e5%ad%a6%e4%b8%ad%e7%9a%84%e5%ba%94%e7%94%a8%e4%b8%a8%e5%91%a8%e6%97%a5","status":"publish","type":"post","link":"https:\/\/swarma.org\/?p=46431","title":{"rendered":"\u57fa\u7840\u6a21\u578b\u5728\u8c03\u63a7\u57fa\u56e0\u7ec4\u5b66\u548cRNA\u79d1\u5b66\u4e2d\u7684\u5e94\u7528\u4e28\u5468\u65e5\u76f4\u64ad\u00b7\u751f\u7269\u533b\u5b66\u5927\u6a21\u578b\u8bfb\u4e66\u4f1a"},"content":{"rendered":"
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\u5bf9\u4e8eDNA\u800c\u8a00\uff0c\u4e0d\u8bba\u8c03\u63a7\u57fa\u56e0\u7ec4\u5b66\u4e0e\u86cb\u767d\u548c\u5176\u4ed6\u8c03\u63a7\u5206\u5b50\u591a\u4e48\u76f8\u5173\uff0c\u5b83\u59cb\u7ec8\u4f5c\u4e3a\u8c03\u63a7\u57fa\u56e0\u7ec4\u5b66\u7684\u7814\u7a76\u6838\u5fc3\u3002\u6545\u800c\uff0c\u5728\u672c\u5468\u65e5\u4e0a\u534810:00\uff0c\u6211\u4eec\u5c06\u7531\u5c60\u946b\u660e\u8001\u5e08\u5e26\u9886\u6211\u4eec\u56de\u987e\u6df1\u5ea6\u5b66\u4e60\u5728\u8fd9\u4e2a\u65b9\u5411\u7684\u5e94\u7528\uff0c\u540c\u65f6\u63a2\u8ba8DNA\u5927\u6a21\u578b\u5728\u57fa\u56e0\u8c03\u63a7\u4e2d\u7684\u6f5c\u5728\u5e94\u7528\u4ee5\u53ca\u76ee\u524d\u5de5\u4f5c\u7684\u4e00\u4e9b\u5c40\u9650\u6027\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u7531\u4e8eRNA\u5206\u5b50\u548c\u5176\u76f8\u4e92\u4f5c\u7528\u7684\u590d\u6742\u6027\uff0cRNA\u79d1\u5b66\u7684\u53d1\u5c55\u4e00\u76f4\u76f8\u5bf9\u8f83\u6162\uff0c\u7f3a\u4e4f\u7cfb\u7edf\u6027\u7684\u7406\u89e3\u3002\u5e78\u8fd0\u7684\u662f\uff0cUni-RNA\u63d0\u51fa\u4e86\u89c4\u6a21\u6700\u5927\u7684RNA\u5e8f\u5217\u9884\u8bad\u7ec3\u6a21\u578b\uff0c\u4ece\u800c\u9488\u5bf9\u6027\u5730\u89e3\u51b3\u4e86\u90e8\u5206RNA\u7814\u7a76\u4e2d\u7684\u95ee\u9898\u3002\u56e0\u6b64\uff0c\u5728\u672c\u6b21\u5206\u4eab\u4f1a\u4e2d\uff0c\u5c06\u7531\u738b\u559c\u8001\u5e08\u5e26\u9886\u6211\u4eec\u4ecb\u7ecdUni-RNA\uff0c\u5e76\u5c55\u671b\u672a\u6765RNA\u79d1\u5b66\u7684\u7814\u7a76\u65b9\u5411\u3002<\/span><\/strong><\/p>\n<\/section>\n

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\u96c6\u667a\u4ff1\u4e50\u90e8\u8054\u5408\u897f\u6e56\u5927\u5b66\u52a9\u7406\u6559\u6388\u5434\u6cf0\u9716\u3001\u65af\u5766\u798f\u5927\u5b66\u8ba1\u7b97\u673a\u79d1\u5b66\u7cfb\u535a\u58eb\u540e\u7814\u7a76\u5458\u738b\u701a\u5bb8\u3001\u535a\u58eb\u7814\u7a76\u751f\u9ec4\u67ef\u946b\u3001\u9ec4\u5029\uff0c\u534e\u76db\u987f\u5927\u5b66\u535a\u58eb\u7814\u7a76\u751f\u5c60\u946b\u660e\uff0c\u5171\u540c\u53d1\u8d77\u4ee5\u201c\u5927\u6a21\u578b\u4e0e\u751f\u7269\u533b\u5b66<\/a>\u201d\u4e3a\u4e3b\u9898\u7684\u8bfb\u4e66\u4f1a\uff0c\u5171\u5b66\u5171\u7814\u76f8\u5173\u6587\u732e\uff0c\u63a2\u8ba8\u57fa\u7840\u6a21\u578b\u5728\u751f\u7269\u533b\u5b66\u7b49\u79d1\u5b66\u9886\u57df\u7684\u5e94\u7528\u3001\u5f71\u54cd\u548c\u5c55\u671b\u3002\u8bfb\u4e66\u4f1a\u4ece2023\u5e748\u670820\u65e5\u5f00\u59cb\uff0c\u6bcf\u5468\u65e5\u65e9\u4e0a 9:00-11:00 \u7ebf\u4e0a\u4e3e\u884c\uff0c\u6301\u7eed\u65f6\u95f4\u9884\u8ba18\u5468\u3002\u6b22\u8fce\u5bf9\u63a2\u7d22\u8fd9\u4e2a\u6fc0\u52a8\u4eba\u5fc3\u7684\u524d\u6cbf\u9886\u57df\u6709\u5174\u8da3\u7684\u670b\u53cb\u62a5\u540d\u53c2\u4e0e\u3002<\/span><\/strong><\/p>\n

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DNA \u5927\u6a21\u578b\u5728\u8c03\u63a7\u57fa\u56e0\u7ec4\u5b66\u4e2d\u7684\u7efc\u8ff0\u548c\u5c55\u671b<\/strong><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/span><\/strong><\/strong><\/p>\n<\/section>\n

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1 \u57fa\u7840\u80cc\u666f\u77e5\u8bc6\u4ecb\u7ecd\uff1aIntroduction to regulatory genomics<\/span><\/p>\n

2 \u5bf9\u57fa\u56e0\u8c03\u63a7\u7ec4\u5b66\u7684\u6982\u8ff0\uff1aFramework to Understand regulatory genomics<\/span><\/p>\n

3 DNA\u8bed\u8a00\u5927\u6a21\u578b\u5de5\u4f5c\u56de\u987e\uff1aOverview of DNA language models<\/span><\/p>\n

4 \u5bf9\u672a\u6765\u7684\u5c55\u671b\uff1aDiscussion<\/span><\/section>\n

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Uni-RNA\u9884\u8bad\u7ec3\u5927\u6a21\u578b\u5728RNA\u79d1\u5b66\u4e2d\u7684\u5e94\u7528<\/strong><\/strong><\/span><\/strong><\/strong><\/p>\n<\/section>\n

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RNA\u5728\u751f\u547d\u6d3b\u52a8\u4e2d\u626e\u6f14\u7740\u81f3\u5173\u91cd\u8981\u7684\u89d2\u8272\uff0c\u4f5c\u4e3a\u57fa\u56e0\u4fe1\u606f\u4f20\u9012\uff08\u8f6c\u5f55\u8fc7\u7a0b\uff09\u7684\u6838\u5fc3\u5206\u5b50\uff0c\u5b83\u7684\u91cd\u8981\u6027\u4e0d\u53ef\u5ffd\u89c6\u3002\u7136\u800c\uff0c\u7531\u4e8eRNA\u5206\u5b50\u53ca\u5176\u76f8\u4e92\u4f5c\u7528\u5173\u7cfb\u7684\u590d\u6742\u6027\uff0cRNA\u79d1\u5b66\u957f\u671f\u4ee5\u6765\u4e00\u76f4\u53d1\u5c55\u7f13\u6162\uff0c\u5b66\u672f\u754c\u5bf9RNA\u79d1\u5b66\u4ecd\u7136\u7f3a\u4e4f\u7cfb\u7edf\u7684\u6846\u67b6\u6027\u7406\u89e3\u3002<\/span><\/section>\n

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\u5728\u6b64\u80cc\u666f\u4e0b\uff0c\u7531\u738b\u559c\u8001\u5e08\u4f5c\u4e3a\u4e3b\u8981\u5f00\u53d1\u8005\u4e4b\u4e00\u7684Uni-RNA\u6210\u4e3a\u4e86\u8fc4\u4eca\u4e3a\u6b62\u89c4\u6a21\u6700\u5e9e\u5927\u7684RNA\u5e8f\u5217\u9884\u8bad\u7ec3\u6a21\u578b\uff0c\u5b83\u5305\u62ec\u51e0\u4e4e\u6240\u6709\u5df2\u77e5\u79cd\u7c7b\u7684RNA\uff0c\u7528\u4e8e\u8bad\u7ec3\u548c\u5b66\u4e60\u3002\u8fd9\u4e00\u521b\u65b0\u6027\u7684\u6a21\u578b\u4e0d\u4ec5\u4e3aRNA\u79d1\u5b66\u63d0\u4f9b\u4e86\u524d\u6240\u672a\u6709\u7684\u5de5\u5177\uff0c\u8fd8\u5728\u4f17\u591a\u4e0b\u6e38\u4efb\u52a1\u4e0a\u5c55\u73b0\u4e86\u6700\u9886\u5148\u7684\u6027\u80fd\uff0c\u5982RNA\u7ed3\u6784\u9884\u6d4b\u3001mRNA\u6027\u8d28\u9884\u6d4b\u4ee5\u53caRNA\u751f\u7269\u5b66\u529f\u80fd\u7684\u9884\u6d4b\u3002\u8fd9\u4e00\u8fdb\u5c55\u4e3a\u7814\u7a76\u4eba\u5458\u63d0\u4f9b\u4e86\u66f4\u5f3a\u5927\u7684\u8d44\u6e90\uff0c\u4ece\u800c\u6709\u671b\u6df1\u5316\u6211\u4eec\u5bf9RNA\u7684\u7406\u89e3\uff0c\u63a8\u52a8\u5b66\u754c\u5728\u8fd9\u4e00\u9886\u57df\u7684\u63a2\u7d22\u548c\u53d1\u73b0\u3002<\/span><\/section>\n

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