{"id":47733,"date":"2024-01-17T18:06:58","date_gmt":"2024-01-17T10:06:58","guid":{"rendered":"https:\/\/swarma.org\/?p=47733"},"modified":"2024-01-17T18:06:58","modified_gmt":"2024-01-17T10:06:58","slug":"pnas%e9%80%9f%e9%80%92%ef%bc%9a%e5%a4%9a%e6%a8%a1%e6%80%81%e5%9b%be%e5%83%8ftransformer%e7%b3%bb%e7%bb%9f%e7%b2%be%e5%87%86%e4%bc%b0%e8%ae%a1%e7%94%9f%e7%89%a9%e5%ad%a6%e5%b9%b4%e9%be%84%e5%8f%8a","status":"publish","type":"post","link":"https:\/\/swarma.org\/?p=47733","title":{"rendered":"PNAS\u901f\u9012\uff1a\u591a\u6a21\u6001\u56fe\u50cftransformer\u7cfb\u7edf\u7cbe\u51c6\u4f30\u8ba1\u751f\u7269\u5b66\u5e74\u9f84\u53ca\u9884\u6d4b\u75be\u75c5"},"content":{"rendered":"
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\u5173\u952e\u8bcd\uff1a\u591a\u6a21\u6001\uff0c\u751f\u7269\u5b66\u5e74\u9f84\uff0c\u75be\u75c5\u9884\u6d4b\uff0c\u533b\u5b66\u56fe\u50cf<\/strong><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/span><\/strong><\/strong><\/strong><\/span><\/p>\n


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\u8bba\u6587\u9898\u76ee\uff1aAccurate estimation of biological age and its application in disease prediction using a multimo<\/span>dal image Transformer system<\/span><\/span><\/section>\n
\u8bba\u6587\u671f\u520a\uff1aPNAS<\/em><\/em><\/span><\/section>\n
\u8bba\u6587\u5730\u5740\uff1ahttps:\/\/www.pnas.org\/doi\/10.1073\/pnas.2308812120<\/span><\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/blockquote>\n

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\u4e2a\u4f53\u7684\u8870\u8001\u662f\u6307\u8eab\u4f53\u6ee1\u8db3\u751f\u7406\u9700\u6c42\u7684\u80fd\u529b\u5728\u65f6\u95f4\u4e0a\u7684\u53d8\u5316\uff0c\u4e3b\u8981\u662f\u964d\u4f4e\u3002\u8870\u8001\u8fc7\u7a0b\u662f\u4e0d\u53ef\u907f\u514d\u7684\uff0c\u4e5f\u662f\u6162\u6027\u75be\u75c5\u7684\u4e00\u4e2a\u98ce\u9669\u56e0\u7d20\u3002\u6bcf\u4e2a\u4eba\u7684\u751f\u7269\u5e74\u9f84<\/span>\uff08Biological Age\uff09<\/span>\u5305\u542b\u8870\u8001\u7684\u7ed3\u6784\u548c\u529f\u80fd\u51b3\u5b9a\u56e0\u7d20\uff0c\u5176\u4e0e\u5b9e\u9645\u5e74\u9f84\u7684\u5dee\u503c<\/span>\uff08AgeDiff\uff09<\/span>\u53ef\u7528\u4f5c\u6f5c\u5728\u75c5\u75c7\u5bfc\u81f4\u52a0\u901f\u8870\u8001\u7684\u751f\u7269\u6807\u8bb0\u3002\u751f\u7269\u5b66\u5e74\u9f84\u662f\u8861\u91cf\u8870\u8001\u7684\u751f\u7269\u6807\u5fd7\u7269\uff0c\u53ef\u7528\u4e8e\u5bf9\u4eba\u7fa4\u8fdb\u884c\u5206\u5c42\uff0c\u4ee5\u9884\u6d4b\u67d0\u4e9b\u4e0e\u5e74\u9f84\u76f8\u5173\u7684\u6162\u6027\u75be\u75c5\u3002\u751f\u7269\u5e74\u9f84\u53ef\u901a\u8fc7\u8111\u78c1\u5171\u632f\u6210\u50cf\u3001\u89c6\u7f51\u819c\u6216\u9762\u90e8\u56fe\u50cf\u7b49\u751f\u7269\u533b\u5b66\u7279\u5f81\u8fdb\u884c\u9884\u6d4b\uff0c\u4f46\u8870\u8001\u8fc7\u7a0b\u4e2d\u56fa\u6709\u7684\u5f02\u8d28\u6027\u9650\u5236\u4e86\u901a\u8fc7\u5355\u4e2a\u8eab\u4f53\u7cfb\u7edf\u9884\u6d4b\u751f\u7269\u5e74\u9f84\u7684\u5b9e\u7528\u6027\u3002<\/span><\/section>\n

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\u8be5\u6587\u63cf\u8ff0\u4e86\u4e00\u79cd\u57fa\u4e8e Transformer \u7684\u591a\u6a21\u6001\u67b6\u6784\uff0c\u5b83\u53ef\u4ee5\u6839\u636e\u9762\u90e8\u3001\u773c\u5e95\u548c\u820c\u5934\u56fe\u50cf\u4f30\u7b97\u751f\u7269\u5b66\u5e74\u9f84\u3002\u7814\u7a76\u4f7f\u7528\u6765\u81ea 11,223 \u540d\u5065\u5eb7\u53d7\u8bd5\u8005\u7684\u9762\u90e8\u3001\u820c\u5934\u548c\u89c6\u7f51\u819c\u56fe\u50cf\u5bf9\u6a21\u578b\u8fdb\u884c\u4e86\u8bad\u7ec3\uff0c\u7ed3\u679c\u8868\u660e\uff0c\u878d\u5408\u4e09\u79cd\u56fe\u50cf\u6a21\u5f0f\u53ef\u5b9e\u73b0\u6700\u51c6\u786e\u7684\u751f\u7269\u5b66\u5e74\u9f84\u9884\u6d4b\u3002\u7814\u7a76\u8005\u5728 2,840 \u540d\u60a3\u6709\u516d\u79cd\u6162\u6027\u75be\u75c5\u7684\u6d4b\u8bd5\u4eba\u7fa4\u4e2d\u9a8c\u8bc1\u4e86\u8be5\u65b9\u6cd5\uff0c\u7ed3\u679c\u53d1\u73b0\uff0c\u5b9e\u9645\u5e74\u9f84\u4e0e BA \u4e4b\u95f4\u7684\u5dee\u5f02\u660e\u663e\u5927\u4e8e\u5065\u5eb7\u4eba\u3002\u672c\u7814\u7a76\u8868\u660e\uff0cAgeDiff \u6709\u6f5c\u529b\u4f5c\u4e3a\u4e00\u79cd\u72ec\u7acb\u7684\u751f\u7269\u6807\u8bb0\u7269\uff0c\u6216\u4e0e\u5176\u4ed6\u5df2\u77e5\u56e0\u7d20\u4e00\u8d77\u7528\u4e8e\u6162\u6027\u75be\u75c5\u7684\u98ce\u9669\u5206\u5c42\u548c\u8fdb\u5c55\u9884\u6d4b\u3002\u672c\u7814\u7a76\u63cf\u8ff0\u4e00\u79cd\u5229\u7528\u5bb9\u6613\u83b7\u5f97\u7684\u60a3\u8005\u6570\u636e\u6765\u8bc6\u522b\u6162\u6027\u75be\u75c5\u7684\u65b9\u6cd5\uff0c\u5176\u7ed3\u679c\u51f8\u663e\u4e86\u4f7f\u7528\u591a\u6a21\u6001\u56fe\u50cf\u6765\u4f30\u8ba1\u548c\u5206\u6790\u8870\u8001\u8fc7\u7a0b\u7684\u53ef\u884c\u6027\u3002<\/span><\/section>\n

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\u56fe1. (A) \u7ed3\u5408\u89c6\u7f51\u819c\u56fe\u50cf\u3001\u820c\u5934\u56fe\u50cf\u548c\u9762\u90e8\u56fe\u50cf\u8fdb\u884c\u751f\u7269\u5b66\u5e74\u9f84\u4f30\u7b97\uff1b(B) \u4eba\u5de5\u667a\u80fd\u7cfb\u7edf\u5728\u534e\u5317\u5065\u5eb7\u5bf9\u7167\u6570\u636e\u96c6\u4e0a\u8fdb\u884c\u4e86\u8bad\u7ec3\u548c\u9a8c\u8bc1\uff0c\u5e76\u5728\u534e\u5317\u4e0d\u5065\u5eb7\u6570\u636e\u96c6\u548c\u534e\u5357\u6570\u636e\u96c6\u4e0a\u8fdb\u884c\u4e86\u6d4b\u8bd5\uff1b(C) \u4eba\u5de5\u667a\u80fd\u7cfb\u7edf\u7ec6\u8282\uff1b(D) \u591a\u6a21\u6001\u878d\u5408\u65b9\u5f0f\u3002<\/span><\/p>\n


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\u56fe3\uff1aSHAP\u65b9\u6cd5\u5206\u6790\u5f71\u54cd\u751f\u7269\u5b66\u5e74\u9f84\u4e0e\u5b9e\u9645\u5e74\u9f84\u5dee\u5f02\u503c\u7684\u56e0\u7d20<\/span><\/section>\n


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AI + Science\u7b2c\u4e8c\u5b63\u8bfb\u4e66\u4f1a\u542f\u52a8<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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\u5927\u6a21\u578b\u4e0e\u751f\u7269\u533b\u5b66\uff1aAI + Science\u7b2c\u4e8c\u5b63\u8bfb\u4e66\u4f1a\u542f\u52a8<\/a><\/span>
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\u200d<\/span>\u63a8\u8350\u9605\u8bfb<\/span><\/strong><\/strong><\/strong><\/section>\n
1. <\/strong>\u75be\u75c5\u7684\u9ad8\u7ef4\u7a7a\u95f4\uff1a\u5c06\u75be\u75c5\u4f5c\u4e3a\u6574\u4f53\u66f4\u6709\u52a9\u4e8e\u75be\u75c5\u9884\u6d4b | Nat. Comput. Sci.\u901f\u9012<\/a><\/strong><\/span><\/strong><\/strong><\/section>\n
2. <\/strong>\u5df4\u62c9\u5df4\u897f\u65b0\u4f5c\uff1aAI-Bind \u52a9\u529b\u86cb\u767d\u8d28-\u914d\u4f53\u7ed3\u5408\u9884\u6d4b<\/a><\/strong><\/span><\/strong><\/strong><\/section>\n
3.<\/strong> \u80fd\u591f\u9884\u6d4b\u86cb\u767d\u8d28\u7ed3\u6784\u3001\u63a7\u5236\u6838\u805a\u53d8\u7684AI\uff0c\u600e\u6837\u4fc3\u8fdb\u79d1\u5b66\u7406\u89e3\uff1f<\/a><\/strong><\/strong><\/strong><\/span><\/section>\n
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4. <\/strong><\/strong><\/span>\u5f20\u6c5f\uff1a\u7b2c\u4e09\u4ee3\u4eba\u5de5\u667a\u80fd\u6280\u672f\u57fa\u7840\u2014\u2014\u4ece\u53ef\u5fae\u5206\u7f16\u7a0b\u5230\u56e0\u679c\u63a8\u7406 | \u96c6\u667a\u5b66\u56ed\u5168\u65b0\u8bfe\u7a0b<\/a><\/strong><\/strong><\/span><\/section>\n
5. <\/strong><\/strong><\/strong><\/strong>\u52a0\u5165\u96c6\u667a\u5b66\u56edVIP\uff0c\u4e00\u6b21\u6027\u83b7\u53d6\u96c6\u667a\u5e73\u53f0\u6240\u6709\u5185\u5bb9\u8d44\u6e90<\/a><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/span><\/strong><\/strong><\/strong><\/section>\n
6. <\/strong>\u52a0\u5165\u96c6\u667a\uff0c\u4e00\u8d77\u590d\u6742\uff01<\/strong><\/span><\/a><\/section>\n

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\u70b9\u51fb\u201c\u9605\u8bfb\u539f\u6587\u201d\uff0c\u62a5\u540d\u8bfb\u4e66\u4f1a<\/strong><\/span><\/strong><\/span><\/strong><\/p>\n

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\u5173\u952e\u8bcd\uff1a\u591a\u6a21\u6001\uff0c\u751f\u7269\u5b66\u5e74\u9f84\uff0c\u75be\u75c5\u9884\u6d4b\uff0c\u533b\u5b66\u56fe\u50cf \u8bba\u6587\u9898\u76ee\uff1aAccurate estimation of biological age and its application in disease prediction using a multimodal image Transformer syst…<\/p>\n","protected":false},"author":0,"featured_media":47726,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"special":[],"_links":{"self":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/47733"}],"collection":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=47733"}],"version-history":[{"count":0,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/47733\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/media\/47726"}],"wp:attachment":[{"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=47733"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=47733"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=47733"},{"taxonomy":"special","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fspecial&post=47733"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}