{"id":55185,"date":"2025-01-23T20:58:26","date_gmt":"2025-01-23T12:58:26","guid":{"rendered":"https:\/\/swarma.org\/?p=55185"},"modified":"2025-01-23T20:58:26","modified_gmt":"2025-01-23T12:58:26","slug":"%e7%94%9f%e5%91%bd%e8%b5%b7%e6%ba%90%e6%97%b6%e5%a4%8d%e6%9d%82%e7%94%9f%e5%8c%96%e7%b3%bb%e7%bb%9f%e5%a6%82%e4%bd%95%e6%bc%94%e5%8c%96%ef%bc%9fnature-chemistry-%e6%9c%80%e6%96%b0%e7%a0%94%e7%a9%b6","status":"publish","type":"post","link":"https:\/\/swarma.org\/?p=55185","title":{"rendered":"\u751f\u547d\u8d77\u6e90\u65f6\u590d\u6742\u751f\u5316\u7cfb\u7edf\u5982\u4f55\u6f14\u5316\uff1fNature Chemistry \u6700\u65b0\u7814\u7a76\u63d0\u51fa\u5206\u5b50\u62fc\u88c5\u5047\u8bf4"},"content":{"rendered":"
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\u8bba\u6587\u9898\u76ee\uff1aIntellectual frameworks to understand complex biochemical systems at the origin of life<\/span><\/section>\n
\u8bba\u6587\u5730\u5740\uff1ahttps:\/\/www.nature.com\/articles\/s41557-024-01698-4<\/span><\/section>\n
\u671f\u520a\u540d\u79f0\uff1aNature Chemistry<\/em><\/span><\/section>\n<\/blockquote>\n

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\u751f\u547d\u7684\u8d77\u6e90\u6d89\u53ca\u4ece\u7b80\u5355\u5206\u5b50\u5230\u590d\u6742\u7cfb\u7edf\u7684\u6f14\u5316\u8fc7\u7a0b\uff0c\u4f8b\u5982\u86cb\u767d\u8d28\u7ffb\u8bd1\u3002\u86cb\u767d\u8d28\u7ffb\u8bd1\u662f\u73b0\u4ee3\u751f\u547d\u4f53\u4e2d\u9ad8\u5ea6\u590d\u6742\u4e14\u4e0d\u53ef\u6216\u7f3a\u7684\u7cfb\u7edf\uff0c\u5176\u590d\u6742\u6027\u4ee4\u4eba\u96be\u4ee5\u60f3\u8c61\u5982\u4f55\u4ece\u7b80\u5355\u7684\u5206\u5b50\u57fa\u7840\u6f14\u5316\u800c\u6765\u3002\u4f20\u7edf\u7684\u201cRNA\u4e16\u754c\u7406\u8bba\u201d\u63d0\u51fa\uff0cRNA\u65e2\u662f\u9057\u4f20\u4fe1\u606f\u7684\u8f7d\u4f53\uff0c\u4e5f\u662f\u50ac\u5316\u53cd\u5e94\u7684\u9176\uff0c\u4ece\u800c\u89e3\u51b3\u4e86DNA\u548c\u86cb\u767d\u8d28\u201c\u5148\u6709\u9e21\u8fd8\u662f\u5148\u6709\u86cb\u201d\u7684\u6096\u8bba\u3002\u7136\u800c\uff0c\u8be5\u7406\u8bba\u5728\u89e3\u91ca\u590d\u6742\u7cfb\u7edf\u7684\u8fdb\u4e00\u6b65\u8fdb\u5316\u65b9\u9762\u5b58\u5728\u5c40\u9650\u6027\u3002\u8fd1\u671f\u53d1\u8868\u5728Nature Chemistry<\/em>\u7684\u89c2\u70b9\u6587\u7ae0\u63d0\u51fa\u201c\u5206\u5b50\u62fc\u88c5\u5047\u8bf4\u201d<\/span>\uff08molecular bricolage\uff09<\/span>\uff0c\u8ba4\u4e3a\u590d\u6742\u7cfb\u7edf\u7684\u90e8\u4ef6\u6700\u521d\u8fdb\u5316\u4e3a\u4e0e\u73b0\u4ee3\u529f\u80fd\u65e0\u5173\u7684\u5176\u4ed6\u7528\u9014\uff0c\u8fd9\u4e9b\u90e8\u4ef6\u901a\u8fc7\u5076\u7136\u7684\u5173\u8054\u9010\u6e10\u5f62\u6210\u65b0\u7684\u529f\u80fd\uff0c\u6700\u7ec8\u6f14\u5316\u4e3a\u9ad8\u5ea6\u590d\u6742\u7684\u7cfb\u7edf\u3002<\/span><\/section>\n

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\u9996\u5148\uff0c\u7814\u7a76\u8005\u63d0\u51fa\u5206\u5b50\u62fc\u88c5\u7684\u4e24\u9636\u6bb5\u6a21\u578b\uff0c\u5c06\u590d\u6742\u7cfb\u7edf\u7684\u8fdb\u5316\u5206\u4e3a\u521d\u59cb\u548c\u7ec4\u5408\u9636\u6bb5\u3002\u5728\u521d\u59cb\u9636\u6bb5<\/strong>\u9636\u6bb5\uff0c\u5404\u90e8\u4ef6\u4e3a\u4e86\u7279\u5b9a\u7684\u65e9\u671f\u529f\u80fd\u800c\u8fdb\u5316\uff0c\u5982RNA\u3001\u86cb\u767d\u8d28\u6216\u7b80\u5355\u7684\u5206\u5b50\uff0c\u4f46\u8fd9\u4e9b\u529f\u80fd\u4e0e\u7cfb\u7edf\u7684\u6700\u7ec8\u529f\u80fd\u65e0\u5173\u3002\u4f8b\u5982\uff0c\u65e9\u671ftRNA\u53ef\u80fd\u4ec5\u4f5c\u4e3a\u50ac\u5316\u7684\u8f85\u52a9\u56e0\u5b50\uff0c\u800c\u975e\u4fe1\u606f\u9002\u914d\u5668\u3002\u5728\u7ec4\u5408\u9636\u6bb5<\/strong>\u9636\u6bb5\uff0c\u8fd9\u4e9b\u90e8\u4ef6\u5076\u7136\u5f62\u6210\u7c97\u7cd9\u7684\u96c6\u5408\u4f53\uff0c\u5c55\u73b0\u51fa\u65b0\u7684\u529f\u80fd\uff0c\u8fd9\u79cd\u65b0\u529f\u80fd\u4e3a\u751f\u7269\u4f53\u63d0\u4f9b\u9002\u5e94\u6027\u4f18\u52bf\uff0c\u4ece\u800c\u53d7\u5230\u81ea\u7136\u9009\u62e9\u7684\u5f3a\u5316\u3002<\/span><\/section>\n

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\u6587\u7ae0\u5217\u4e3e\u4e86\u652f\u6301\u5206\u5b50\u62fc\u88c5\u7684\u591a\u4e2a\u5b9e\u9a8c\u4e0e\u5316\u5b66\u673a\u5236\uff0c\u4e3a\u5206\u5b50\u62fc\u88c5\u6a21\u578b\u63d0\u4f9b\u652f\u6301\u3002\u975e\u9176\u4fc3RNA\u590d\u5236<\/strong>\uff1a\u6c28\u9170\u5316RNA\u53ef\u80fd\u4fc3\u8fdbRNA\u7684\u5feb\u901f\u590d\u5236\uff0c\u5c3d\u7ba1\u8fd9\u4e00\u529f\u80fd\u6700\u521d\u4e0e\u86cb\u767d\u8d28\u7ffb\u8bd1\u65e0\u5173\uff1b\u80bd\u548cRNA\u7684\u76f8\u4e92\u4f5c\u7528<\/strong>\uff1a\u7b80\u5355\u7684\u539f\u80bd\u53ef\u4ee5\u589e\u52a0RNA\u7684\u7a33\u5b9a\u6027\u6216\u4f5c\u4e3a\u50ac\u5316\u56e0\u5b50\u8f85\u52a9\u53cd\u5e94\uff1b\u539f\u59cb\u6838\u7cd6\u4f53\u7684\u529f\u80fd<\/strong>\uff1a\u6838\u7cd6\u4f53\u53ef\u80fd\u6700\u521d\u5e76\u975e\u7528\u4e8e\u86cb\u767d\u8d28\u5408\u6210\uff0c\u800c\u662f\u4f5c\u4e3aRNA\u590d\u5236\u9176\u53d1\u6325\u4f5c\u7528\uff0c\u968f\u540e\u9010\u6e10\u88ab\u7528\u4e8e\u86cb\u767d\u8d28\u7ffb\u8bd1\u3002\u6587\u7ae0\u8fdb\u4e00\u6b65\u8ba8\u8bba\u4e86\u5206\u5b50\u62fc\u88c5\u5047\u8bf4\u5728\u5176\u4ed6\u751f\u547d\u8d77\u6e90\u95ee\u9898\u4e2d\u7684\u5e94\u7528\uff0c\u4f8b\u5982\uff0c\u5b9e\u9a8c\u548c\u8ba1\u7b97\u5206\u6790\u663e\u793a\uff0c\u4ee3\u8c22\u7f51\u7edc<\/strong>\u53ef\u80fd\u901a\u8fc7\u91cd\u65b0\u5229\u7528<\/span>\uff08co-option\uff09<\/span>\u73b0\u6709\u8def\u5f84\u800c\u6269\u5c55\uff1b\u8102\u8d28\u4e0eRNA\u7684\u76f8\u4e92\u4f5c\u7528\u53ef\u4ee5\u589e\u5f3a\u5206\u5b50\u529f\u80fd\uff0c\u4e3a\u539f\u59cb\u7ec6\u80de\u7684\u5f62\u6210<\/strong>\u63d0\u4f9b\u652f\u6301\u3002<\/span><\/section>\n

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\u56fe 1. \u73b0\u4ee3\u7684\u86cb\u767d\u8d28\u7ffb\u8bd1\u5728\u6240\u6709\u5df2\u77e5\u7684\u751f\u547d\u5f62\u5f0f\u4e2d\u90fd\u88ab\u4fdd\u7559\u4e0b\u6765\uff0c\u5e76\u4e14\u9700\u8981\u7531\u8bb8\u591a\u76f8\u4e92\u4f5c\u7528\u7684\u90e8\u5206\u7ec4\u6210\u7684\u590d\u6742\u5206\u5b50\u673a\u5668\u6765\u5b9e\u73b0\u3002<\/span><\/p>\n


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\u56fe 2. \u86cb\u767d\u8d28\u7ffb\u8bd1\u4e2d\u751f\u5316\u5143\u7d20\u8d77\u6e90\u7684\u5047\u8bbe\u8def\u5f84\u3002<\/span><\/section>\n

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\u56fe 3. \u5355\u4e00\u9009\u62e9\u538b\u529b\u4e0e\u5206\u5b50\u62fc\u88c5\u7684\u793a\u610f\u56fe\u3002<\/span><\/section>\n

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\u56fe 4. \u7f16\u7801\u86cb\u767d\u8d28\u5408\u6210\u6240\u9700\u7684\u5143\u7d20\uff0c\u88ab\u5047\u8bbe\u6700\u521d\u4e3a\u4e0d\u76f8\u5173\u7684\u529f\u80fd\u800c\u8fdb\u5316\u3002<\/span><\/p>\n

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\u81ea\u751f\u6210\u7ed3\u6784\u8bfb\u4e66\u4f1a\u542f\u52a8\uff1a\u5256\u89e3\u751f\u547d\u3001\u610f\u8bc6\u4e0e\u667a\u80fd\u7684\u6838\u5fc3\u7ed3\u6784<\/a><\/span>
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\u63a8\u8350\u9605\u8bfb<\/span><\/strong><\/strong><\/strong><\/section>\n
1. <\/strong>\u751f\u547d\u6709\u673a\u4f53\u4ece\u4f55\u8d77\u6e90\uff1fScience \u8bc4\u8bba\u300a\u751f\u547d\u7684\u8d77\u6e90\u300b\u53d1\u8868100\u5468\u5e74<\/a><\/strong><\/span><\/strong><\/section>\n
2. <\/strong>\u5408\u6210\u4eba\u9020\u751f\u547d\u7684\u7406\u8bba\u89c6\u89d2\uff1a\u4ece\u751f\u547d\u8d77\u6e90\u4e2d\u5b66\u4e60<\/a><\/strong><\/span><\/strong><\/section>\n
3. <\/strong>\u751f\u547d\u8d77\u6e90\u4e0e\u590d\u6742\u6027 | \u5218\u5b87\u8bbf\u8c08<\/a><\/strong><\/span><\/strong><\/section>\n
4. <\/strong><\/span>\u5f20\u6c5f\uff1a\u7b2c\u4e09\u4ee3\u4eba\u5de5\u667a\u80fd\u6280\u672f\u57fa\u7840\u2014\u2014\u4ece\u53ef\u5fae\u5206\u7f16\u7a0b\u5230\u56e0\u679c\u63a8\u7406 | \u96c6\u667a\u5b66\u56ed\u5168\u65b0\u8bfe\u7a0b<\/a><\/strong><\/strong><\/span><\/section>\n
<\/strong>5. <\/strong>\u9f99\u5e74\u5927\u8fd0\u8d77\uff0c\u5b66\u4e60\u6b63\u5f53\u65f6\uff01\u89e3\u9501\u96c6\u667a\u5168\u7ad9\u5185\u5bb9\uff0c\u5f00\u542f\u65b0\u5e74\u5b66\u4e60\u8ba1\u5212<\/a><\/strong><\/section>\n

6. <\/strong>\u52a0\u5165\u96c6\u667a\uff0c\u4e00\u8d77\u590d\u6742\uff01<\/strong><\/span><\/a><\/p>\n


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\u70b9\u51fb\u201c\u9605\u8bfb\u539f\u6587\u201d\uff0c\u62a5\u540d\u8bfb\u4e66\u4f1a<\/span><\/section>\n

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