{"id":58246,"date":"2025-04-08T18:46:18","date_gmt":"2025-04-08T10:46:18","guid":{"rendered":"https:\/\/swarma.org\/?p=58246"},"modified":"2025-04-08T18:46:18","modified_gmt":"2025-04-08T10:46:18","slug":"science%ef%bc%9a%e4%ba%ba%e7%b1%bb%e6%84%8f%e8%af%86%e6%84%9f%e7%9f%a5%e7%9a%84%e9%97%b8%e9%97%a8-%e9%ab%98%e9%98%b6%e4%b8%98%e8%84%91%e6%a0%b8%e5%9b%a2","status":"publish","type":"post","link":"https:\/\/swarma.org\/?p=58246","title":{"rendered":"Science\uff1a\u4eba\u7c7b\u610f\u8bc6\u611f\u77e5\u7684\u201c\u95f8\u95e8\u201d\u2014\u2014\u9ad8\u9636\u4e18\u8111\u6838\u56e2"},"content":{"rendered":"
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\u5df2\u77e5\u4eba\u7c7b\u9ad8\u9636\u4e18\u8111\u6838\u56e2\u6d3b\u52a8\u4e0e\u610f\u8bc6\u72b6\u6001\u5bc6\u5207\u76f8\u5173\uff0c\u7136\u800c\u8fd9\u4e9b\u4e18\u8111\u6838\u56e2\u53ca\u4e18\u8111-\u76ae\u5c42\u76f8\u4e92\u4f5c\u7528\u5982\u4f55\u76f4\u63a5\u5f71\u54cd\u4eba\u7c7b\u610f\u8bc6\u611f\u77e5\u7684\u77ac\u65f6\u8fc7\u7a0b\uff08transient process\uff09\u5c1a\u4e0d\u660e\u786e\u3002\u6211\u4eec\u5728\u690d\u5165\u7535\u6781\u60a3\u8005\u6267\u884c\u89c6\u89c9\u610f\u8bc6\u4efb\u52a1\u65f6\uff0c\u540c\u6b65\u8bb0\u5f55\u4e86\u4e18\u8111\u6838\u56e2\u4e0e\u524d\u989d\u53f6\u76ae\u5c42\uff08PFC\uff09\u7684\u7acb\u4f53\u8111\u7535\u56fe\u6570\u636e\u3002\u4e0e\u8179\u4fa7\u6838\u56e2\u53ca\u524d\u989d\u53f6\u76ae\u5c42\u76f8\u6bd4\uff0c\u677f\u5185\u6838\u4e0e\u5185\u4fa7\u6838\u56e2\uff08intralaminar and medial nuclei\uff09\u8868\u73b0\u51fa\u66f4\u65e9\u51fa\u73b0\u4e14\u66f4\u5f3a\u7684\u610f\u8bc6\u76f8\u5173\u6d3b\u52a8\u3002\u5728\u610f\u8bc6\u611f\u77e5\u8fc7\u7a0b\u4e2d\uff0c\u77ac\u65f6\u7684\u4e18\u8111-\u524d\u989d\u53f6\u795e\u7ecf\u540c\u6b65\u4e0e\u8de8\u9891\u6bb5\u8026\u5408\uff08cross-frequency coupling\uff09\u5747\u7531\u677f\u5185\u6838\u548c\u5185\u4fa7\u6838\u56e2\u7684\u03b8\u6ce2\u76f8\u4f4d\u9a71\u52a8\u3002\u7531\u6b64\u53ef\u89c1\uff0c\u677f\u5185\u6838\u4e0e\u5185\u4fa7\u4e18\u8111\u6838\u56e2\u5728\u610f\u8bc6\u611f\u77e5\u4ea7\u751f\u8fc7\u7a0b\u4e2d\u53d1\u6325\u7740\u9a71\u52a8\u524d\u989d\u53f6\u76ae\u5c42\u6d3b\u52a8\u7684”\u95f8\u95e8”\u4f5c\u7528\u3002<\/span><\/span><\/strong><\/p>\n


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\u5173\u952e\u8bcd\uff1a\u9ad8\u9636\u4e18\u8111\u6838\u56e2\uff08high-order thalamic nuclei\uff09\uff0c\u610f\u8bc6\u611f\u77e5\uff0c\u4e18\u8111-\u524d\u989d\u53f6\u73af\u8def\uff08thalamofrontal loop\uff09\uff0c\u7acb\u4f53\u8111\u7535\u56fe\uff08sEEG\uff09\uff0c\u677f\u5185\u6838\u4e0e\u5185\u4fa7\u6838\u56e2\uff08intralaminar and medial nuclei\uff09\uff0c\u03b8\u6ce2\u76f8\u4f4d\u540c\u6b65\uff08theta phase synchronization\uff09<\/span><\/span><\/strong><\/p>\n<\/section>\n

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\u8bba\u6587\u9898\u76ee\uff1aHuman high-order thalamic nuclei gate conscious perception through the thalamofrontal loop<\/span><\/span><\/p>\n

\u53d1\u8868\u65f6\u95f4\uff1a2025\u5e744\u67084\u65e5<\/span><\/span><\/p>\n

\u8bba\u6587\u5730\u5740\uff1ahttps:\/\/www.science.org\/doi\/10.1126\/science.adr3675<\/span><\/span><\/p>\n

\u671f\u520a\u540d\u79f0\uff1a<\/span><\/span>Science<\/span><\/span><\/em><\/p>\n<\/blockquote>\n


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\u63a2\u7d22\u4eba\u7c7b\u610f\u8bc6\u80cc\u540e\u7684\u795e\u7ecf\u57fa\u7840\u662f\u5f53\u4ee3\u79d1\u5b66\u4e2d\u6700\u4ee4\u4eba\u5174\u594b\u548c\u6700\u5177\u6311\u6218\u6027\u7684\u4efb\u52a1\u4e4b\u4e00\u3002\u4f20\u7edf\u7406\u8bba\u8ba4\u4e3a\uff0c\u5927\u8111\u76ae\u5c42<\/span>\uff08cerebral cortex\uff09<\/span>\u662f\u610f\u8bc6\u4ea7\u751f\u7684\u6838\u5fc3\uff0c\u800c\u4e18\u8111<\/span>\uff08thalamus\uff09<\/span>\u4ec5\u4f5c\u4e3a\u611f\u89c9\u4fe1\u606f\u7684\u4e2d\u7ee7\u7ad9\u3002\u8fd1\u671f\uff0c<\/span><\/span>Science<\/span><\/span><\/em>\u53d1\u8868\u7684\u6700\u65b0\u7814\u7a76\uff0c\u901a\u8fc7\u9885\u5185\u7acb\u4f53\u8111\u7535\u56fe<\/span>\uff08sEEG\uff09<\/span>\u6570\u636e\u9996\u6b21\u63ed\u793a\uff1a<\/span><\/span>\u4e18\u8111\u7684\u677f\u5185\u6838\uff08CM\/Pf\uff09\u548c\u5185\u4fa7\u6838\u56e2\uff08MDm\uff09\u901a\u8fc7\u03b8\u6ce2\u76f8\u4f4d\u540c\u6b65\u4e3b\u5bfc\u524d\u989d\u53f6\u76ae\u5c42\uff08PFC\uff09\u6d3b\u52a8\uff0c\u50cf\u201c\u95f8\u95e8\u201d\u4e00\u6837\u63a7\u5236\u610f\u8bc6\u611f\u77e5\u7684\u77ac\u65f6\u6d8c\u73b0<\/span><\/span><\/strong>\u3002\u8fd9\u4e00\u53d1\u73b0\u4e3a\u610f\u8bc6\u7406\u8bba\u63d0\u4f9b\u4e86\u98a0\u8986\u6027\u7684\u795e\u7ecf\u73af\u8def\u8bc1\u636e\u3002<\/span><\/span><\/p>\n


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\u56fe 1. \u89c6\u89c9\u610f\u8bc6\u4efb\u52a1\u3001\u5fc3\u7406\u6d4b\u91cf\u66f2\u7ebf\u548c\u7535\u6781\u5b9a\u4f4d\u3002<\/span><\/span><\/strong>\uff08A\uff09\u89c6\u89c9\u611f\u77e5\u4efb\u52a1\u793a\u610f\u56fe\u3002\uff08B\uff09\u5fc3\u7406\u6d4b\u91cf\u68c0\u6d4b\u66f2\u7ebf\uff08 Psychometric detection curves\uff09\u3002\uff08\u4e0a\uff09\u4e00\u4e2a\u53c2\u4e0e\u8005\u7684\u611f\u77e5\u89c9\u767e\u5206\u6bd4\u793a\u4f8b\u3002\uff08\u4e0b\uff09\u6240\u6709\u53c2\u4e0e\u8005\u7684\u6570\u636e\u3002\u56fe\u4e2d\u7684\u6bcf\u4e2a\u9ed1\u70b9\u8868\u793a\u5728\u76f8\u5173\u5bf9\u6bd4\u6c34\u5e73\u4e0a\u7684\u610f\u8bc6\u767e\u5206\u6bd4\uff0c\u9ed1\u8272\u66f2\u7ebf\u8868\u793a\u62df\u5408\u7684\u5fc3\u7406\u6d4b\u91cf\u51fd\u6570\u3002\u610f\u8bc6\u767e\u5206\u6bd4>25%\u548c<75%\u88ab\u5b9a\u4e49\u4e3a\u63a5\u8fd1\u9608\u503c\uff08near-threshold\uff09\u3002\u5e95\u90e8\u793a\u610f\u56fe\u4e2d\uff0c\u6574\u4f53\u7684\u56fe\u7247\u5bf9\u6bd4\u5ea6\u4e0e\u4e2a\u4f53\u53c2\u4e0e\u8005\u7684\u611f\u77e5\u9608\u503c\uff0850%\u7684\u610f\u8bc6\u767e\u5206\u6bd4\uff09\u4e00\u81f4\u3002N\uff0c\u53c2\u4e0e\u8005\u6570\u91cf\uff1bR2\uff0c\u51b3\u5b9a\u7cfb\u6570\u3002\uff08C\uff09\u5728\u8499\u7279\u5229\u5c14\u795e\u7ecf\u5b66\u7814\u7a76\u6240\uff08MNI\uff09\u5927\u8111\u6a21\u677f\u4e0a\u6295\u5f71\u7684\u6240\u6709\u8bb0\u5f55\u7535\u6781\u70b9\u7684\u5de6\u3001\u53f3\u3001\u4fef\u89c6\u56fe\u3002\u7ea2\u8272\u70b9\u8868\u793a\u4e18\u8111\u7684\u8bb0\u5f55\u90e8\u4f4d\uff0c\u84dd\u8272\u70b9\u8868\u793aPFC\u7684\u8bb0\u5f55\u90e8\u4f4d\u3002<\/span><\/span><\/span><\/p>\n


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\u7814\u7a76\u6700\u5173\u952e\u7684\u53d1\u73b0\u662f<\/span><\/span>\u65f6\u95f4\u5dee<\/span><\/span><\/strong>\u3002\u5728\u8fd1\u9608\u503c-\u6709\/\u65e0\u610f\u8bc6<\/span>\uff08NC\uff0cNU\uff09<\/span>\u7684\u4e24\u79cd\u60c5\u51b5\u4e2d\uff0c\u5149\u6805\u5bf9\u6bd4\u5ea6\u975e\u5e38\u76f8\u4f3c\uff0c\u6240\u4ee5\u8fd9\u4e24\u7c7b\u8bd5\u6b21\u7684\u523a\u6fc0\u540e\u795e\u7ecf\u6d3b\u52a8\u7684\u5dee\u5f02\u5219\u66f4\u591a\u5730\u53cd\u6620\u4e86\u610f\u8bc6\u76f8\u5173\u7684\u4fe1\u606f\uff0c\u800c\u4e0d\u662f\u5bf9\u5149\u6805\u7684\u7b80\u5355\u89c6\u89c9\u53cd\u5e94\u3002\u56e0\u6b64\uff0c\u4e24\u79cd\u60c5\u51b5\u7684\u795e\u7ecf\u6d3b\u52a8\u53d1\u6563\u8d77\u59cb\u65f6\u95f4<\/span>\uff08DOT\uff09<\/span>\u548c\u53d1\u6563\u5e45\u5ea6\u4ee3\u8868\u4e86\u7279\u5b9a\u8bb0\u5f55\u90e8\u4f4d\u89c6\u89c9\u610f\u8bc6\u76f8\u5173\u6d3b\u52a8\u7684\u6f5c\u4f0f\u671f\u548c\u632f\u5e45\u3002\u7ed3\u679c\u663e\u793a\uff0c\u5149\u6805\u51fa\u73b0\u540e200\u6beb\u79d2\uff0c<\/span><\/span>\u677f\u5185\u6838\uff08CM\/Pf\uff09\u548c\u5185\u4fa7\u6838\u56e2\uff08MDm\uff09<\/span><\/span><\/strong>\u5df2\u8868\u73b0\u51fa\u663e\u8457\u7684\u53cd\u6620\u610f\u8bc6\u7684\u4e8b\u4ef6\u76f8\u5173\u7535\u4f4d<\/span>\uff08ERP\uff09<\/span>\u548c\u9891\u8c31\u6270\u52a8<\/span>\uff08ERSP\uff09<\/span>\uff0c\u800c<\/span><\/span>\u8179\u4fa7\u6838\u56e2\uff08VA\/VLa\/VLp\uff09\u548c\u524d\u989d\u53f6\u5916\u4fa7\u533a\uff08LPFC\uff09<\/span><\/span><\/strong>\u7684\u6d3b\u52a8\u5219\u6709\u65f6\u95f4\u5ef6\u8fdf\u3002\u8fd9\u79cd\u5dee\u5f02\u5177\u6709\u89e3\u5256\u5b66\u57fa\u7840\uff1a\u677f\u5185\u6838\u548c\u5185\u4fa7\u6838\u56e2\u5728\u4e18\u8111\u4e2d\u7684\u4f4d\u7f6e\u66f4\u9760\u5185\u4fa7\u548c\u5c3e\u4fa7<\/span>\uff08\u56fe2E\uff09<\/span>\uff0c\u4e14\u4e0e\u5168\u8111\u5e7f\u6cdb\u8fde\u63a5\u3002\u540e\u7eed\u89e3\u7801\u5206\u6790\u8fdb\u4e00\u6b65\u663e\u793a\uff0c\u8fd9\u4e9b\u6838\u56e2\u7684\u795e\u7ecf\u6d3b\u52a8\u7279\u5f02\u6027\u7f16\u7801\u201c\u662f\u5426\u610f\u8bc6\u5230\u201d<\/span>\uff08decoding accuracy 70%\uff09<\/span>\uff0c\u800c\u975e\u5149\u6805\u7269\u7406\u7279\u5f81\u6216\u773c\u52a8\u6307\u4ee4\uff0c\u8bc1\u5b9e\u5176\u76f4\u63a5\u53c2\u4e0e\u610f\u8bc6\u5185\u5bb9\u6784\u5efa\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n

<\/section>\n

\u56fe 2. \u4e18\u8111\u6838\u56e2\u4e2d\u610f\u8bc6\u76f8\u5173\u6d3b\u52a8\u7684\u7279\u5f81\u3002<\/span><\/span><\/strong>\uff08A\uff09\u6bcf\u4e2a\u53c2\u4e0e\u8005\uff08P1\u81f3P5\uff09\u5728\u5355\u4e2a\u8bb0\u5f55\u70b9\u7684sEEG\u6d3b\u52a8\u793a\u4f8b\u3002\u5728\u6bcf\u4e2a\u53c2\u4e0e\u8005\u7684\u56fe\u4e2d\uff0c\u5de6\u56fe\u663e\u793a\u4e86\u56db\u79cd\u4e0d\u540c\u6761\u4ef6\u4e0bsEEG\u6d3b\u52a8\u7684\u603b\u4f53\u5e73\u5747\u503c\u3002\u66f2\u7ebf\u7684\u9634\u5f71\u533a\u57df\u8868\u793a\u626b\u63cf\u7535\u955c\u3002\u4e24\u6761\u9ed1\u8272\u865a\u7ebf\u5206\u522b\u57280\u548c650 ms\u65f6\u8868\u793a\u5149\u6805\u5f00\u59cb\u548c\u6ce8\u89c6\u70b9\u7684\u989c\u8272\u53d8\u5316\u3002\u7c97\u9ed1\u7ebf\u8868\u793aNC\u548cNU\u6761\u4ef6\u4e4b\u95f4\u7684\u663e\u8457\u5dee\u5f02\uff08P < 0.01\u6821\u6b63\uff0c\u72ec\u7acb\u6837\u672ct\u68c0\u9a8c\uff09\u3002\u6bcf\u4e2a\u9762\u677f\u7684\u53f3\u4fa7\u663e\u793a\u4e86\u5728NC\uff08\u4e0a\uff09\u548cNU\uff08\u4e0b\uff09\u6761\u4ef6\u4e0b\u7684\u5355\u6b21\u8bd5\u9a8c\u4e2d\u7684sEEG\u632f\u5e45\u3002\u6bcf\u4e2a\u56fe\u4e2d\u7684\u989c\u8272\u6761\u8868\u793asEEG\u632f\u5e45\u3002\uff08B ~ D\uff09\u4e18\u8111\u6838\u4f53\u73b0\u610f\u8bc6\u76f8\u5173\u8bb0\u5f55\u4f4d\u70b9\u7684\u767e\u5206\u6bd4\uff08B\uff09\u3001\u52a8\u6001\u767e\u5206\u6bd4\uff08C\uff09\u548c\u53d1\u6563\u5f00\u59cb\u65f6\u95f4DOTs \uff08D\uff09\u3002\u5728D\u4e2d\uff0c\u6bcf\u6761\u5185\u7684\u9ed1\u70b9\u8868\u793a\u6838\u56e2\u5185\u8bb0\u5f55\u4f4d\u70b9\u7684DOTs\u3002** p < 0.01\u3002\uff08E\uff09\u89e3\u5256\u4f4d\u7f6e\u4e0eDOTs\u7684\u76f8\u5173\u6027\u3002R\uff0c\u76f8\u5173\u7cfb\u6570\u3002\uff08F\uff09\u4e18\u8111\u6838\u4e2d\u610f\u8bc6\u76f8\u5173\u6d3b\u52a8\u7684\u632f\u5e45\u3002\u989c\u8272\u4e0eB\u6240\u793a\u76f8\u540c\u30020\u548c650 ms\u65f6\u4e24\u6761\u9ed1\u8272\u865a\u7ebf\u5206\u522b\u8868\u793a\u5149\u6805\u8d77\u59cb\u548c\u5b9a\u70b9\u7684\u989c\u8272\u53d8\u5316\u3002\uff08G\uff09\u4e18\u8111\u6838\u56e2\u7684\u4e09\u7ef4\u91cd\u5efa\u56fe\u3002<\/span><\/span><\/span><\/p>\n


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\u03b8\u6ce2\u76f8\u4f4d\u540c\u6b65\uff1a<\/span><\/strong><\/span><\/strong><\/strong><\/p>\n

\u4e18\u8111\u9a71\u52a8\u524d\u989d\u53f6\u7684\u201c\u795e\u7ecf\u4ea4\u6d41\u201d\u673a\u5236<\/span><\/strong><\/span><\/strong><\/strong><\/p>\n<\/section>\n

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<\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n


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\u7814\u7a76\u901a\u8fc7\u76f8\u4f4d\u9501\u5b9a\u503c<\/span>\uff08PLV\uff09<\/span>\u548c\u76f8\u4f4d\u4f20\u9012\u71b5<\/span>\uff08PTE\uff09<\/span>\u5206\u6790\u53d1\u73b0\uff0c\u610f\u8bc6\u51fa\u73b0\u65f6\uff0c\u677f\u5185\u6838\u548c\u5185\u4fa7\u6838\u56e2<\/span>\uff08imTha\uff09<\/span>\u7684\u03b8\u6ce2<\/span>\uff082-8 Hz\uff09<\/span>\u76f8\u4f4d\u4f1a\u7387\u5148\u540c\u6b65<\/span>\uff08\u56fe3\uff09<\/span>\uff0c\u5e76\u5f15\u5bfc\u524d\u989d\u53f6\u7684\u03b3\u6ce2\u6bb5<\/span>\uff0860-150 Hz\uff09<\/span>\u632f\u5e45\u632f\u8361\u3002\u8fd9\u79cd\u8de8\u9891\u6bb5\u8026\u5408<\/span>\uff08cross-frequency coupling\uff09<\/span>\u5448\u73b0\u660e\u786e\u7684<\/span><\/span>\u65b9\u5411\u6027<\/span><\/span><\/strong>\uff1a\u4ece\u4e18\u8111\u5230\u524d\u989d\u53f6\u7684\u4fe1\u606f\u6d41\u5f3a\u5ea6\u663e\u8457\u9ad8\u4e8e\u53cd\u5411\u4ece\u524d\u989d\u53f6\u5230\u4e18\u8111\u7684\u4fe1\u606f\u6d41<\/span>\uff08P = 5.55\u00d710\u207b\u00b9\u2077\uff09<\/span>\uff0c\u4e14\u6700\u62b5\u8fbe\u7684\u4fe1\u606f\u51fa\u73b0\u5728\u524d\u989d\u53f6\u5916\u4fa7\u533a<\/span>\uff08LPFC\uff09<\/span>\u3002\u7814\u7a76\u8005\u6bd4\u55bb\uff1a\u201c\u5c31\u50cf\u4e50\u961f\u6307\u6325\u7528\u03b8\u6ce2\u8282\u62cd\u7edf\u4e00\u5404\u58f0\u90e8\uff0c\u4e18\u8111\u901a\u8fc7\u76f8\u4f4d\u540c\u6b65\u5c06\u5206\u6563\u7684\u76ae\u5c42\u6d3b\u52a8\u6574\u5408\u4e3a\u8fde\u8d2f\u7684\u610f\u8bc6\u4f53\u9a8c\u3002\u201d<\/span><\/span><\/p>\n


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<\/section>\n

\u56fe 3. \u610f\u8bc6\u76f8\u5173\u7684\u4e18\u8111\u6838\u56e2-\u524d\u989d\u53f6\u76f8\u4f4d\u9501\u5b9a\u3002<\/span><\/span><\/strong>\uff08A\u548cB\uff09\u4e24\u4e2a\u53c2\u4e0e\u8005\uff08P1\u548cP4\uff09\u5728\u4f20\u611f\u5668\u6c34\u5e73\uff08n*n\uff09\u7684PLV\u53d8\u5316\u3002\u4ece\u5de6\u5230\u53f3\uff0c\u5728\u6709\u610f\u8bc6\uff08\u4e0a\u56fe\uff09\u548c\u65e0\u610f\u8bc6\uff08\u4e0b\u56fe\uff09\u8bd5\u9a8c\u4e2d\u5149\u6805\u51fa\u73b0\u540e0,100,200,300,400\u548c500ms\u7684\u65f6\u95f4\u70b9\uff0c\u6bcf\u4e2a\u8bb0\u5f55\u70b9\u4e4b\u95f4\u7684PLV\u3002\u989c\u8272\u8868\u793aPLV \uff08\u03b8\u6ce2\u6bb5\uff09\u3002\u9ed1\u7ebf\u8868\u793a\u4e18\u8111\u533a\u57df\u548cPFC\u533a\u57df\u7684\u8fb9\u754c\u3002N\u4e3a\u8bb0\u5f55\u4f4d\u70b9\u6570\u3002(C)\u6839\u636e\u4e18\u8111\u6838\u548cPFC\u4e9a\u533a\u5206\u7ec4\u7684PLV\u7ed3\u679c\uff0c\u663e\u793a\u4e86\u6240\u6709\u53c2\u4e0e\u8005\u7684\u603b\u4f53\u7ed3\u679c\u3002\u4e0b\u56fe\u663e\u793a\u4e86\u6709\u610f\u8bc6\u548c\u65e0\u610f\u8bc6\u8bd5\u9a8c\u4e4b\u95f4PLV\u7684\u5dee\u5f02\u3002(D)\u4e18\u8111\u548cPFC\u4e4b\u95f4\u7684\u5e73\u5747PLV\u3002\uff08\u5de6\u56fe\uff09\u6240\u6709\u53c2\u4e0e\u8005\u7684\u603b\u4f53\u7ed3\u679c\u3002\uff08\u53f3\u9762\u677f\uff09\u53c2\u4e0e\u80051\u81f35 \uff08P1\u81f3P5\uff09\u7684\u4e2a\u4eba\u7ed3\u679c\u3002(E) \u03b8\u6ce2\u6bb5\u7684\u4e2a\u4f53\uff08\u4e0a\u56fe\uff09\u548c\u7fa4\u4f53\uff08\u4e0b\u56fe\uff09PTE\u7ed3\u679c\u3002(F)\u4e18\u8111\u677f\u95f4\u6838\u548c\u5185\u4fa7\u6838\uff08imTha\uff09\u4e0ePFC\u4e9a\u533a\u4e4b\u95f4\u7684\u5e73\u5747PLV\u3002\uff08\u5de6\u56fe\uff09\u6240\u6709\u53c2\u4e0e\u8005\u7684\u603b\u4f53\u7ed3\u679c\u3002\uff08\u53f3\u56fe\uff09\u4e2a\u4eba\u7ed3\u679c\u3002\u5bf9\u4e8e\u53c2\u4e0e\u80055\uff0c\u7531\u4e8e\u91c7\u6837\u6709\u9650\uff0c\u5176\u4ed6PFC\u5206\u533a\u7684\u7ed3\u679c\u7f3a\u5931\u3002<\/span><\/span><\/span><\/p>\n


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\u7406\u8bba\u7a81\u7834\uff1a<\/span><\/strong><\/span><\/strong><\/strong><\/p>\n

\u4ece\u201c\u76ae\u5c42\u4e2d\u5fc3\u8bba\u201d\u5230\u201c\u4e18\u8111-\u76ae\u5c42\u53cc\u7cfb\u7edf\u6a21\u578b\u201d<\/span><\/strong><\/span><\/strong><\/strong><\/p>\n<\/section>\n

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<\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n


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\u8fd9\u4e00\u53d1\u73b0\u6311\u6218\u4e86\u4e3b\u6d41\u201c\u5168\u5c40\u795e\u7ecf\u5143\u5de5\u4f5c\u7a7a\u95f4\u201d<\/span>\uff08Global Neuronal Workspace\uff09<\/span>\u7b49\u76ae\u5c42\u4e2d\u5fc3\u7406\u8bba\u3002\u8bba\u6587\u63d0\u51fa\u4fee\u6b63\u6a21\u578b\uff1a<\/span><\/span>\u540e\u76ae\u5c42\u201c\u70ed\u70b9\u533a\u201d\uff08Hot Zone\uff09\u751f\u6210\u610f\u8bc6\u5185\u5bb9\u521d\u7a3f\u540e\uff0c\u4e18\u8111\u677f\u5185\u6838\u548c\u5185\u4fa7\u6838\u56e2\u4f5c\u4e3a\u201c\u95f8\u95e8\u201d\u51b3\u5b9a\u662f\u5426\u5c06\u5176\u5e7f\u64ad\u81f3\u524d\u989d\u53f6\u7b49\u9ad8\u7ea7\u533a\u57df<\/span><\/span><\/strong>\uff08\u56fe4\uff09<\/span>\u3002\u8fd9\u79cd\u5206\u5de5\u89e3\u91ca\u4e86\u4e3a\u4f55\u4e18\u8111\u635f\u4f24\u4f1a\u5bfc\u81f4\u610f\u8bc6\u969c\u788d<\/span>\uff08\u5982\u690d\u7269\u72b6\u6001\uff09<\/span>\uff0c\u800c\u76ae\u5c42\u635f\u4f24\u591a\u5f71\u54cd\u7279\u5b9a\u610f\u8bc6\u5185\u5bb9\u3002\u7814\u7a76\u8fd8\u6697\u793a\uff0c\u7ef4\u6301\u89c9\u9192\u72b6\u6001<\/span>\uff08conscious state\uff09<\/span>\u4e0e\u611f\u77e5\u5185\u5bb9<\/span>\uff08conscious perception\uff09<\/span>\u53ef\u80fd\u5171\u4eab\u540c\u4e00\u5957\u4e18\u8111\u8c03\u63a7\u673a\u5236\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n

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\u56fe 4. imTha\u548cLPFC\u4e2d\u610f\u8bc6\u76f8\u5173\u6d3b\u52a8\u7684\u7279\u5f81\u3002<\/span><\/span><\/strong>(A) imTha\u548cLPFC\u4e2d\u610f\u8bc6\u76f8\u5173\u8bb0\u5f55\u4f4d\u70b9\u7684\u767e\u5206\u6bd4\u3002(B) imTha\u548cLPFC\u7684\u5ef6\u8fdf\uff08DOTs\uff09\u3002\u7070\u6761\u548c\u9ed1\u6761\u5206\u522b\u8868\u793aimTha\u548cLPFC\u7684\u5e73\u5747DOTs\u3002\u6bcf\u4e2a\u6761\u5f62\u5185\u7684\u5f69\u8272\u70b9\u4ee3\u8868\u6bcf\u4e2a\u533a\u57df\u5185\u8bb0\u5f55\u70b9\u7684\u70b9\u3002\u6bcf\u79cd\u989c\u8272\u4ee3\u8868\u6bcf\u4e2a\u53c2\u4e0e\u8005\u7684\u6570\u636e\u3002** p < 0.01\u3002(C) imTha\u548cLPFC\u4e2d\u610f\u8bc6\u76f8\u5173\u6d3b\u52a8\u7684\u632f\u5e45\u3002\u84dd\u8272\u548c\u6a59\u8272\u7684\u7ebf\u5206\u522b\u4ee3\u8868imTha\u548cPFC\u3002\u4e24\u6761\u9ed1\u8272\u865a\u7ebf\u5206\u522b\u57280\u548c650 ms\u65f6\u8868\u793a\u5149\u6805\u5f00\u59cb\u548c\u6ce8\u89c6\u70b9\u7684\u989c\u8272\u53d8\u5316\u3002\u9ed1\u8272\u5b9e\u7ebf\u8868\u793aimTha\u548cPFC\u7684\u632f\u5e45\u663e\u8457\u4e0d\u540c\u7684\u5468\u671f\u3002\uff08D\u3001E\uff09 imTha\u548cLPFC\u4e2d\u4e0e\u610f\u8bc6\u76f8\u5173\u7684ERP\u4f4d\u70b9\u7684\u03b8\u6ce2\u6bb5\u76f8\u4f4d\u96c6\u4e2d\u6307\u6570\uff08phase concentration index\uff09\u3002\u4e24\u6761\u9ed1\u8272\u865a\u7ebf\u5206\u522b\u57280\u548c650 ms\u65f6\u8868\u793a\u5149\u6805\u5f00\u59cb\u548c\u6ce8\u89c6\u70b9\u7684\u989c\u8272\u53d8\u5316\u3002\u9ed1\u8272\u5b9e\u7ebf\u8868\u793a\u6709\u610f\u8bc6\u548c\u65e0\u610f\u8bc6\u72b6\u6001\u4e0b\u76f8\u4f4d\u96c6\u4e2d\u6307\u6807\u663e\u8457\u4e0d\u540c\u7684\u5468\u671f\u3002\u53f3\u8fb9\u7684\u70ed\u56fe\u663e\u793a\u4e86\u6240\u6709\u610f\u8bc6\u76f8\u5173\u90e8\u4f4d\u7684\u76f8\u4f4d\u96c6\u4e2d\u6307\u6570\u3002\uff08F\u548cG\uff09 imTha\u548cLPFC\u7684\u610f\u8bc6\u76f8\u5173ERP\u4f4d\u70b9\u7684\u03b8\u6ce2\u6bb5\u5927\u5c0f\u3002\u4e0e(D)\u6240\u793a\u76f8\u540c\uff0c\u4f46\u03b8\u6ce2\u6bb5\u5927\u5c0f\u4e0d\u540c\u3002<\/span><\/span><\/span><\/p>\n


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\u7814\u7a76\u521b\u65b0\u4e0e\u672a\u6765\u5c55\u671b<\/span><\/strong><\/span><\/strong><\/strong><\/p>\n<\/section>\n

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<\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n


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\u7814\u7a76\u7684\u6280\u672f\u4eae\u70b9\u5728\u4e8e\u514b\u670d\u4e86\u4f20\u7edf\u6df1\u90e8\u8111\u523a\u6fc0<\/span>\uff08DBS\uff09<\/span>\u7535\u6781\u8986\u76d6\u6709\u9650\u7684\u7f3a\u9677\uff0c\u5229\u7528194\u4e2a\u4e18\u8111\u8bb0\u5f55\u4f4d\u70b9\u548c213\u4e2a\u524d\u989d\u53f6\u4f4d\u70b9\u7684sEEG\u6570\u636e\uff0c\u9996\u6b21\u5b9e\u73b0\u4eba\u7c7b\u4e18\u8111\u6838\u56e2\u7684\u9ad8\u65f6\u7a7a\u5206\u8fa8\u7387\u89e3\u6790\u3002\u56e2\u961f\u8bbe\u8ba1\u7684\u89c6\u89c9\u4efb\u52a1\u901a\u8fc7\u5339\u914d\u201c\u6709\/\u65e0\u610f\u8bc6\u201d\u8bd5\u6b21\u7684\u773c\u52a8\u53cd\u5e94<\/span>\uff08saccadic response\uff09<\/span>\uff0c\u6709\u6548\u6392\u9664\u4e86\u8fd0\u52a8\u62a5\u544a\u5bf9\u795e\u7ecf\u4fe1\u53f7\u7684\u6c61\u67d3\u3002\u672a\u6765\uff0c\u8fd9\u4e00\u53d1\u73b0\u53ef\u80fd<\/span><\/span>\u4e3a\u610f\u8bc6\u969c\u788d\u60a3\u8005\u5f00\u53d1\u9488\u5bf9\u4e18\u8111\u7684\u9776\u5411\u95ed\u73af\u795e\u7ecf\u8c03\u63a7\u7597\u6cd5\u3002<\/span><\/span><\/strong>\u5c3d\u7ba1\u7814\u7a76\u53d6\u5f97\u91cd\u5927\u7a81\u7834\uff0c\u4f46\u4e5f\u6307\u51fa\u82e5\u5e72\u5f00\u653e\u95ee\u9898\uff1a<\/span><\/span>\u677f\u5185\u6838\u5982\u4f55\u4e0e\u540e\u76ae\u5c42\u201c\u70ed\u70b9\u533a\u201d\u4e92\u52a8\uff1f\u03b8-\u03b3\u8026\u5408\u662f\u5426\u5b58\u5728\u4e8e\u5176\u4ed6\u611f\u77e5\u6a21\u6001\uff1f<\/span><\/span><\/strong>\u8fd9\u4e9b\u8c1c\u9898\u6709\u5f85\u7ed3\u5408\u7315\u7334\u6a21\u578b\u548c\u8ba1\u7b97\u5efa\u6a21\u8fdb\u4e00\u6b65\u63a2\u7d22\u3002\u8fd9\u9879\u5de5\u4f5c\u5c06\u610f\u8bc6\u7814\u7a76\u4ece\u2018\u76f8\u5173\u5173\u7cfb\u2019\u63a8\u5411\u2018\u56e0\u679c\u5173\u7cfb\u2019\uff0c\u4e3a\u7406\u89e3\u5927\u8111\u6700\u795e\u79d8\u7684\u610f\u8bc6\u6d8c\u73b0\u73b0\u8c61\u6253\u5f00\u4e86\u65b0\u7ef4\u5ea6\u3002<\/span><\/span><\/p>\n


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\u6574\u5408\u4fe1\u606f\u8bba\u8bfb\u4e66\u4f1a<\/span><\/strong>
<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


<\/span><\/section>\n

\u4e3a\u4ec0\u4e48\u6211\u4eec\u5728\u6e05\u9192\u65f6\u6709\u610f\u8bc6\uff0c\u800c\u5728\u65e0\u68a6\u7684\u7761\u7720\u4e2d\u610f\u8bc6\u6c34\u5e73\u5927\u5927\u964d\u4f4e\uff1f\u4e3a\u4ec0\u4e48\u6211\u4eec\u7684\u610f\u8bc6\u7531\u5927\u8111\u7684\u67d0\u4e9b\u90e8\u5206\u4ea7\u751f\uff0c\u800c\u975e\u5176\u4ed6\u90e8\u5206\uff1f\u4e3a\u4ec0\u4e48\u5927\u8111\u7684\u7279\u5b9a\u90e8\u5206\u4e0e\u89c6\u89c9\u548c\u542c\u89c9\u7b49\u610f\u8bc6\u4f53\u9a8c\u5bc6\u5207\u76f8\u5173\uff1f\u8fd9\u4e9b\u5177\u4f53\u7684\u95ee\u9898\u672c\u8d28\u4e0a\u6d89\u53ca\u5230\uff0c\u7406\u89e3\u51b3\u5b9a\u4e00\u4e2a\u7cfb\u7edf\u4ea7\u751f\u610f\u8bc6\u4f53\u9a8c\u7684\u6761\u4ef6\uff0c\u4ee5\u53ca\u7406\u89e3\u51b3\u5b9a\u4e00\u4e2a\u7cfb\u7edf\u5177\u6709\u4f55\u79cd\u610f\u8bc6\u7684\u6761\u4ef6\u3002\u6574\u5408\u4fe1\u606f\u8bba\uff08IIT\uff09\u8bd5\u56fe\u7528\u51e0\u4f55\u5b66\u4e00\u822c\u7684\u516c\u7406\u4f53\u7cfb\u6765\u89e3\u91ca\u610f\u8bc6\u662f\u4ec0\u4e48\uff0c\u610f\u8bc6\u5982\u4f55\u6d4b\u91cf\u3002\u6839\u636e\u8be5\u7406\u8bba\uff0c\u610f\u8bc6\u5bf9\u5e94\u4e8e\u4e00\u4e2a\u7cfb\u7edf\u6574\u5408\u4fe1\u606f\u7684\u80fd\u529b\u3002<\/span><\/span><\/p>\n


<\/span><\/span><\/p>\n

\u4e3a\u4e86\u6df1\u5165\u63a2\u7d22\u610f\u8bc6\u5965\u79d8\uff0c\u7cfb\u7edf\u68b3\u7406\u6574\u5408\u4fe1\u606f\u8bba\u7684\u7406\u8bba\u4f53\u7cfb\uff0c\u5317\u4eac\u5e08\u8303\u5927\u5b66\u7cfb\u7edf\u79d1\u5b66\u5b66\u9662\u6559\u6388\u3001\u96c6\u667a\u4ff1\u4e50\u90e8\u521b\u59cb\u4eba\u5f20\u6c5f\u9886\u8854\u53d1\u8d77\u300c\u6574\u5408\u4fe1\u606f\u8bba\u300d\u8bfb\u4e66\u4f1a<\/a>\uff0c\u7ec4\u7ec7\u5bf9\u672c\u8bdd\u9898\u611f\u5174\u8da3\u7684\u670b\u53cb\uff0c\u6df1\u5165\u7814\u8bfb\u76f8\u5173\u6587\u732e\uff0c\u6fc0\u53d1\u79d1\u7814\u7075\u611f\u3002\u8bfb\u4e66\u4f1a\u5206\u4e3a\u4ee5\u4e0b\u51e0\u4e2a\u90e8\u5206\uff1a\u6574\u5408\u4fe1\u606f\u8bba\u7efc\u8ff0\uff0c\u57fa\u7840\u7406\u8bba\u6846\u67b6\uff0c\u8fd1\u4f3c\u8ba1\u7b97\u65b9\u6cd5\uff0c\u5728\u795e\u7ecf\u79d1\u5b66\u4e2d\u7684\u5e94\u7528\uff0c\u5728\u590d\u6742\u7cfb\u7edf\u4e2d\u7684\u62d3\u5c55\u5e94\u7528\uff0c\u03a6\u4e0e\u7cfb\u7edf\u4e34\u754c\u6001\uff0c\u4ee5\u53ca\u673a\u5668\u610f\u8bc6\u30022024\u5e749\u670828\u65e5\u5f00\u59cb\uff0c\u6bcf\u5468\u516d\u4e0a\u53489:00-11:00\u8fdb\u884c\uff0c\u6301\u7eed\u65f6\u95f4\u9884\u8ba1 10 \u5468\uff0c\u6b22\u8fce\u611f\u5174\u8da3\u7684\u670b\u53cb\u62a5\u540d\u53c2\u4e0e\uff01<\/span><\/span><\/p>\n


<\/span><\/span><\/p>\n

\"\u56fe\u7247\"<\/a><\/span><\/span><\/span><\/p>\n


<\/span><\/span><\/section>\n
\u8be6\u60c5\u8bf7\u89c1\uff1a<\/span><\/span><\/section>\n
\u610f\u8bc6\u53ef\u4ee5\u5ea6\u91cf\u5417\uff1f\u6574\u5408\u4fe1\u606f\u8bba\u8bfb\u4e66\u4f1a\u542f\u52a8\u5566\uff01<\/a><\/span><\/span><\/strong><\/span><\/section>\n


<\/span><\/p>\n


<\/span><\/p>\n<\/section>\n

\u63a8\u8350\u9605\u8bfb<\/span><\/span><\/strong><\/strong><\/strong><\/section>\n
<\/strong><\/section>\n
1. 124\u4f4d\u79d1\u5b66\u5bb6\u6279\u8bc4\u6574\u5408\u4fe1\u606f\u8bba\u662f\u4f2a\u79d1\u5b66\uff1a\u6211\u4eec\u8be5\u5982\u4f55\u63a2\u8ba8\u610f\u8bc6\u96be\u9898\uff1f<\/span><\/a><\/span><\/strong>
<\/span><\/strong><\/span><\/section>\n
2. \u610f\u8bc6\u7814\u7a76\u662f\u201c\u79d1\u5b66\u201d\u8fd8\u662f\u201c\u4f2a\u79d1\u5b66\u201d\uff1f\u4e24\u5927\u610f\u8bc6\u8303\u5f0f\u7684\u4ea4\u950b<\/span><\/a><\/span><\/strong>
<\/span><\/strong><\/span><\/section>\n
3. Tononi vs Seth\uff1a\u610f\u8bc6\u7814\u7a76\uff0c\u5e94\u5f53\u9075\u4ece\u5185\u5728\u89c6\u89d2\u8fd8\u662f\u89c2\u5bdf\u8005\u89c6\u89d2\uff1f<\/span><\/a><\/span><\/strong><\/section>\n
<\/strong><\/section>\n
4. <\/span><\/strong><\/span>\u6d8c\u73b0\u52a8\u529b\u5b66\u5982\u4f55\u7528\u6765\u5206\u6790\u590d\u6742\u7cfb\u7edf\uff1f | \u65b0\u8bfe\u4e0a\u7ebf<\/a><\/span><\/strong><\/strong><\/span><\/section>\n
<\/strong>5. <\/span><\/strong>AI\u65f6\u4ee3\u7684\u5b66\u4e60\uff1a\u5171\u63a2\u4eba\u7c7b\u5b66\u4e60\u7684\u590d\u6742\u6027<\/span><\/a><\/span><\/strong><\/section>\n

6. <\/span><\/strong>\u63a2\u7d22\u8005\u8ba1\u5212 | \u96c6\u667a\u4ff1\u4e50\u90e82025\u5185\u5bb9\u56e2\u961f\u62db\u52df\uff08\u5168\u804c&\u517c\u804c\uff09<\/a><\/span><\/strong><\/span><\/p>\n


<\/span><\/p>\n


<\/span><\/span><\/p>\n

\u70b9\u51fb\u201c\u9605\u8bfb\u539f\u6587\u201d\uff0c\u62a5\u540d\u8bfb\u4e66\u4f1a<\/span><\/span><\/section>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u6458\u8981 \u5df2\u77e5\u4eba\u7c7b\u9ad8\u9636\u4e18\u8111\u6838\u56e2\u6d3b\u52a8\u4e0e\u610f\u8bc6\u72b6\u6001\u5bc6\u5207\u76f8\u5173\uff0c\u7136\u800c\u8fd9\u4e9b\u4e18\u8111\u6838\u56e2\u53ca\u4e18\u8111-\u76ae\u5c42\u76f8\u4e92\u4f5c\u7528\u5982\u4f55\u76f4\u63a5\u5f71\u54cd\u4eba\u7c7b\u610f\u8bc6\u611f\u77e5\u7684\u77ac\u65f6\u8fc7\u7a0b\uff08transient process\uff09\u5c1a\u4e0d\u660e\u786e\u3002\u6211\u4eec\u5728\u690d\u5165\u7535\u6781\u60a3\u8005\u6267\u884c\u89c6\u89c9\u610f\u8bc6\u4efb\u52a1\u65f6\uff0c\u540c\u6b65\u8bb0\u5f55\u4e86\u4e18\u8111\u6838\u56e2\u4e0e\u524d\u989d\u53f6\u76ae\u5c42\uff08PFC\uff09\u7684\u7acb\u4f53\u8111\u7535\u56fe\u6570\u636e\u3002\u4e0e\u8179\u4fa7\u6838\u56e2\u53ca\u524d\u989d\u53f6\u76ae\u5c42\u76f8\u6bd4\uff0c\u677f\u5185\u6838\u4e0e…<\/p>\n","protected":false},"author":0,"featured_media":58237,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"special":[],"_links":{"self":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/58246"}],"collection":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=58246"}],"version-history":[{"count":0,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/58246\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/media\/58237"}],"wp:attachment":[{"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=58246"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=58246"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=58246"},{"taxonomy":"special","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fspecial&post=58246"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}