{"id":64664,"date":"2025-09-21T13:20:35","date_gmt":"2025-09-21T05:20:35","guid":{"rendered":"https:\/\/swarma.org\/?p=64664"},"modified":"2025-09-21T13:20:35","modified_gmt":"2025-09-21T05:20:35","slug":"%e8%87%aa%e7%84%b6%c2%b7%e6%96%b9%e6%b3%95%ef%bc%9a%e6%89%b0%e5%8a%a8ai%e5%ad%aa%e7%94%9f%e8%84%91%ef%bc%8c%e5%88%bb%e7%94%bb%e8%84%91%e7%bd%91%e7%bb%9c%e5%9b%a0%e6%9e%9c","status":"publish","type":"post","link":"https:\/\/swarma.org\/?p=64664","title":{"rendered":"\u81ea\u7136\u00b7\u65b9\u6cd5\uff1a\u6270\u52a8AI\u5b6a\u751f\u8111\uff0c\u523b\u753b\u8111\u7f51\u7edc\u56e0\u679c"},"content":{"rendered":"
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<\/strong>\u5927\u8111\u662f\u4e00\u4e2a\u7531\u591a\u4e2a\u76f8\u4e92\u8fde\u63a5\u7684\u8111\u533a\u7ec4\u6210\u7684\u590d\u6742\u7f51\u7edc\uff0c\u7406\u89e3\u8fd9\u4e9b\u8111\u533a\u4e4b\u95f4\u4fe1\u606f\u5982\u4f55\u6d41\u52a8\uff0c\u662f\u63ed\u793a\u5927\u8111\u5de5\u4f5c\u673a\u5236\u7684\u6838\u5fc3\u95ee\u9898\u4e4b\u4e00\u3002\u4f20\u7edf\u7684\u7ed3\u6784\u8fde\u63a5\uff08SC\uff09\u548c\u529f\u80fd\u8fde\u63a5\uff08FC\uff09\u96be\u4ee5\u63ed\u793a\u4fe1\u606f\u5728\u5927\u8111\u4e2d\u7684\u65b9\u5411\u6027\u4f20\u9012\u4e0e\u56e0\u679c\u7ed3\u6784\u3002\u6709\u6548\u8fde\u63a5\uff08EC\uff09\u5219\u901a\u8fc7\u6355\u6349\u8111\u533a\u4e4b\u95f4\u7684\u56e0\u679c\u4ea4\u4e92\uff0c\u5f25\u8865\u4e86\u8fd9\u4e00\u5173\u952e\u7a7a\u767d\u4f46\u5f80\u5f80\u4f9d\u8d56\u4fb5\u5165\u5f0f\u64cd\u4f5c\uff0c\u4e14\u96be\u4ee5\u6269\u5c55\u5230\u5168\u8111\u5c3a\u5ea6\u3002\u8fd1\u5e74\u6765\uff0c\u4eba\u5de5\u795e\u7ecf\u7f51\u7edc\uff08ANN\uff09\u5728\u795e\u7ecf\u6570\u636e\u5efa\u6a21\u4e2d\u5c55\u73b0\u51fa\u5de8\u5927\u6f5c\u529b\u3002\u5c06\u6270\u52a8\u5206\u6790\u5f15\u5165 ANN \u7684\u6846\u67b6\u662f\u4e00\u79cd\u975e\u5e38\u6709\u524d\u666f\u7684\u56e0\u679c\u63a8\u65ad\u65b9\u6cd5\u3002<\/span>\u81ea\u7136\u00b7\u65b9\u6cd5\uff08Nature Methods\uff09<\/span><\/span><\/strong>\u5357\u65b9\u79d1\u6280\u5927\u5b66\u751f\u7269\u533b\u5b66\u5de5\u7a0b\u7cfb\u5218\u6cc9\u5f71\u56e2\u961f\u63d0\u51fa\u4e86\u795e\u7ecf\u6270\u52a8\u63a8\u65ad\uff08Neural Perturbational Inference, NPI\uff09\u6846\u67b6\uff0c\u901a\u8fc7\u8bad\u7ec3 ANN \u5efa\u6a21\u5927\u5c3a\u5ea6\u795e\u7ecf\u52a8\u529b\u5b66\uff0c\u5e76\u5728\u6a21\u578b\u4e2d\u7cfb\u7edf\u6027\u5730\u65bd\u52a0\u865a\u62df\u6270\u52a8\uff0c\u8fdb\u800c\u7ed8\u5236\u51fa\u5168\u8111\u8303\u56f4\u7684 EC \u56fe\u8c31\uff0c\u8be5\u80fd\u591f\u8bc6\u522b\u5168\u8111 EC \u7684\u65b9\u5411\u3001\u5f3a\u5ea6\uff0c\u4ee5\u53ca\u5174\u594b\/\u6291\u5236\u7279\u5f81\u3002\u76f8\u5173\u7814\u7a76\u6210\u679c\u53d1\u8868\u5728\u671f\u520a\u3002<\/span><\/span><\/strong><\/p>\n


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\u5173\u952e\u8bcd\uff1a\u795e\u7ecf\u6270\u52a8\u63a8\u65ad\uff0c\u7ed3\u6784\u8fde\u63a5\uff0c\u529f\u80fd\u8fde\u63a5\uff0c\u6709\u6548\u8fde\u63a5\uff0c\u56e0\u679c\u63a8\u65ad\uff0c\u4eba\u5de5\u795e\u7ecf\u7f51\u7edc<\/span><\/strong><\/strong><\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u7f57\u5b50\u7fd4\u3001\u6881\u667a\u8d85\u3001\u5218\u6cc9\u5f71\u4e28\u6821\u5bf9<\/span><\/span><\/p>\n


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\u56fe1  | \u57fa\u4e8eAI\u6a21\u578b\u6784\u5efa\u7684\u4e2a\u4f53\u5316\u5b6a\u751f\u8111\u53ef\u4ee5\u9884\u6d4b\u5927\u8111\u7684\u672a\u6765\u72b6\u6001<\/span><\/span><\/p>\n


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\u672c\u6587\u63d0\u51fa\u4e86\u4e00\u79cd\u6570\u636e\u9a71\u52a8\u7684AI\u5b6a\u751f\u8111\u6784\u5efa\u65b9\u6cd5\uff0c\u5e76\u901a\u8fc7\u865a\u62df\u6270\u52a8AI\u5b6a\u751f\u8111\u6765\u63a8\u65ad\u8111\u7f51\u7edc\u56e0\u679c\u5173\u7cfb\u3002\u8be5\u65b9\u6cd5\u88ab\u79f0\u4e3a<\/span><\/span>\u795e\u7ecf\u6270\u52a8\u63a8\u65ad <\/span>(Neural Perturbational Inference, NPI)<\/span><\/span>\u3002\u9996\u5148\uff0cNPI\u4ee5\u81ea\u76d1\u7763\u7684\u5f62\u5f0f\u8bad\u7ec3\u4eba\u5de5\u795e\u7ecf\u7f51\u7edc\u6765\u5efa\u6a21\u8111\u7f51\u7edc\u52a8\u529b\u5b66\uff0c\u5c06\u5176\u4f5c\u4e3aAI\u5b6a\u751f\u8111\u3002\u7136\u540e\uff0c\u901a\u8fc7\u5bf9AI\u5b6a\u751f\u8111\u7684\u6bcf\u4e2a\u8111\u533a\u65bd\u52a0\u865a\u62df\u6270\u52a8\uff0c\u9884\u6d4b\u5176\u4ed6\u8111\u533a\u7684\u54cd\u5e94\uff0c\u4ece\u800c\u523b\u753b\u5168\u8111\u6709\u6548\u8fde\u63a5\u5173\u7cfb\u3002<\/span><\/span><\/span><\/p>\n


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NPI\u4ee3\u7801\u89c1\u672c\u6587\u6700\u540e\u3002<\/span><\/span><\/span><\/p>\n


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\u8bba\u6587\u5f15\u7528\uff1aZixiang Luo, Kaining Peng, Zhichao Liang, Shengyuan Cai, Chenyu Xu, Dan Li, Yu Hu, Changsong Zhou & Quanying Liu*, Mapping effective connectivity by virtually perturbing a surrogate brain. Nature Methods (2025). https:\/\/doi.org\/10.1038\/s41592-025-02654-x<\/span><\/p>\n<\/blockquote>\n


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\u8fd1\u5e74\u6765\uff0c\u4eba\u5de5\u795e\u7ecf\u7f51\u7edc<\/span>\uff08ANN\uff09<\/span>\u5728\u795e\u7ecf\u6570\u636e\u5efa\u6a21\u4e2d\u5c55\u73b0\u51fa\u5de8\u5927\u6f5c\u529b\u3002\u5c06\u6270\u52a8\u5206\u6790\u5f15\u5165 ANN \u7684\u6846\u67b6\u63d0\u4f9b\u4e86\u4e00\u79cd\u6709\u524d\u666f\u7684\u56e0\u679c\u63a8\u65ad\u65b9\u6cd5\uff0c\u53ef\u4ee5\u901a\u8fc7\u8c03\u63a7\u8f93\u5165\u53d8\u91cf\u5e76\u89c2\u5bdf\u8f93\u51fa\u54cd\u5e94\uff0c\u63a8\u65ad\u795e\u7ecf\u7cfb\u7edf\u7684\u56e0\u679c\u7ed3\u6784\u3002\u8fd9\u79cd\u65b9\u6cd5\u5728\u6982\u5ff5\u4e0a\u4e0e\u795e\u7ecf\u79d1\u5b66\u4e2d\u7ecf\u5178\u7684\u201c\u6270\u52a8-\u8bb0\u5f55\u201d\u8303\u5f0f\u76f8\u547c\u5e94\u3002<\/span><\/span><\/p>\n


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\u4e3a\u6b64\uff0c\u6211\u4eec\u63d0\u51fa\u4e86\u795e\u7ecf\u6270\u52a8\u63a8\u65ad<\/span>\uff08Neural Perturbational Inference, NPI\uff09<\/span>\u6846\u67b6\u3002\u8be5\u65b9\u6cd5\u901a\u8fc7\u8bad\u7ec3 ANN \u5efa\u6a21\u5927\u5c3a\u5ea6\u795e\u7ecf\u52a8\u529b\u5b66\uff0c\u5e76\u5728\u6a21\u578b\u4e2d\u7cfb\u7edf\u6027\u5730\u65bd\u52a0\u865a\u62df\u6270\u52a8\uff0c\u8fdb\u800c\u7ed8\u5236\u51fa\u5168\u8111\u8303\u56f4\u7684 EC \u56fe\u8c31\u3002NPI \u6846\u67b6\u80fd\u591f\u8bc6\u522b\u5168\u8111 EC \u7684\u65b9\u5411\u3001\u5f3a\u5ea6\uff0c\u4ee5\u53ca\u5174\u594b\/\u6291\u5236\u7279\u5f81\u3002\u901a\u8fc7\u4f7f\u7528\u591a\u79cd\u5177\u6709\u5df2\u77e5\u771f\u5b9e EC \u7684\u751f\u6210\u6a21\u578b\uff0c\u6211\u4eec\u9a8c\u8bc1\u4e86 NPI \u6846\u67b6\u7684\u6709\u6548\u6027\u3002\u6b64\u5916\uff0cNPI \u63a8\u65ad\u7684\u7ed3\u679c\u8fd8\u4e0e\u76ae\u5c42-\u76ae\u5c42\u8bf1\u53d1\u7535\u4f4d<\/span>\uff08CCEP\uff09<\/span>\u9ad8\u5ea6\u4e00\u81f4\uff0c\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u4e86\u5176\u5728\u53cd\u6620\u771f\u5b9e\u5927\u8111\u56e0\u679c\u4ea4\u4e92\u65b9\u9762\u7684\u51c6\u786e\u6027\u3002<\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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2. \u7ed3\u679c<\/span><\/strong><\/span><\/strong><\/strong><\/p>\n<\/section>\n

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\u795e\u7ecf\u6270\u52a8\u63a8\u65ad(NPI)\u6846\u67b6<\/span><\/span><\/span><\/p>\n


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NPI \u662f\u4e00\u79cd\u6570\u636e\u9a71\u52a8\u7684 EC \u63a8\u65ad\u6846\u67b6\uff0c\u5b83\u91c7\u7528 ANN \u4f5c\u4e3a\u6570\u5b57\u5b6a\u751f\u8111\uff0c\u4ece\u800c\u80fd\u591f\u9ad8\u6548\u5730\u5728\u5168\u8111\u8303\u56f4\u5185\u65bd\u52a0\u6270\u52a8\u5e76\u8bb0\u5f55\u54cd\u5e94\u3002<\/span><\/span><\/p>\n


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\u8111\u529f\u80fd\u6210\u50cf\u548c\u7535\u751f\u7406\u8bb0\u5f55\u80fd\u591f\u63d0\u4f9b\u591a\u4e2a\u8111\u533a\u7684\u6d3b\u52a8\u8bb0\u5f55\uff0c\u4f46\u8fd9\u4e9b\u8111\u533a\u5728\u4fe1\u606f\u5904\u7406\u8fc7\u7a0b\u4e2d\u662f\u5982\u4f55\u4ea4\u4e92\u7684\u4ecd\u4e0d\u6e05\u695a<\/span>\uff08\u56fe 2a\uff09<\/span>\u3002\u9996\u5148\uff0c\u6211\u4eec\u8bad\u7ec3\u4e00\u4e2a ANN\uff0c\u4f7f\u5176\u80fd\u591f\u6839\u636e\u524d\u9762\u4e09\u4e2a\u65f6\u95f4\u70b9\u7684\u72b6\u6001\u9884\u6d4b\u4e0b\u4e00\u4e2a\u65f6\u95f4\u70b9\u7684\u8111\u6d3b\u52a8\uff0c\u8bad\u7ec3\u76ee\u6807\u662f\u6700\u5c0f\u5316\u5355\u6b65\u9884\u6d4b\u8bef\u5dee<\/span>\uff08\u56fe 2b\uff09<\/span>\u3002\u4e3a\u4e86\u9a8c\u8bc1\u8be5 ANN \u662f\u5426\u80fd\u591f\u6355\u6349\u8111\u533a\u4e4b\u95f4\u7684\u4ea4\u4e92\u5173\u7cfb\uff0c\u6211\u4eec\u5c06\u5176\u9884\u6d4b\u8f93\u51fa\u9012\u5f52\u5730\u53cd\u9988\u56de\u6a21\u578b\uff0c\u4ee5\u4ea7\u751f\u6a21\u578b\u751f\u6210\u7684\u795e\u7ecf\u4fe1\u53f7<\/span>\uff08\u56fe 2e\uff09<\/span>\u3002\u6211\u4eec\u4f7f\u7528\u4eba\u7c7b\u9759\u606f\u6001\u529f\u80fd\u78c1\u5171\u632f\u6210\u50cf<\/span>\uff08rs-fMRI\uff09<\/span>\u6570\u636e\uff0c\u5c06\u7531\u6a21\u578b\u751f\u6210\u7684\u4fe1\u53f7\u8ba1\u7b97\u5f97\u5230\u7684\u529f\u80fd\u8fde\u63a5<\/span>\uff08model FC\uff09<\/span>\u4e0e\u771f\u5b9e rs-fMRI \u6570\u636e\u8ba1\u7b97\u5f97\u5230\u7684\u529f\u80fd\u8fde\u63a5<\/span>\uff08empirical FC\uff09<\/span>\u8fdb\u884c\u6bd4\u8f83\uff0c\u4e24\u8005\u8868\u73b0\u51fa\u6781\u9ad8\u7684\u76f8\u5173\u6027\uff0c\u8868\u660e ANN \u6709\u6548\u6355\u6349\u4e86\u8111\u533a\u95f4\u7684\u529f\u80fd\u4f9d\u8d56\u5173\u7cfb<\/span>\uff08\u56fe 2f\uff09<\/span>\u3002\u8fd9\u8868\u660e\uff0c\u8bad\u7ec3\u540e\u7684 ANN \u53ef\u4f5c\u4e3a\u53ef\u9760\u7684\u6570\u5b57\u5b6a\u751f\u8111\uff0c\u7528\u4e8e\u865a\u62df\u6270\u52a8\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n

\u4e4b\u540e\uff0c\u6211\u4eec\u5bf9 ANN \u4e2d\u6bcf\u4e2a\u8282\u70b9\u8fdb\u884c\u6270\u52a8\uff0c\u6bcf\u4e2a\u8282\u70b9\u4ee3\u8868\u4e00\u4e2a\u7279\u5b9a\u7684\u8111\u533a<\/span>\uff08\u56fe 2c\uff09<\/span>\u3002\u6270\u52a8\u901a\u8fc7\u5728\u9009\u5b9a\u8282\u70b9\u7684\u8f93\u5165\u6570\u636e\u4e0a\u65bd\u52a0\u8109\u51b2\u4fe1\u53f7\u5b9e\u73b0<\/span>\uff08\u56fe 2g\uff09<\/span>\u3002\u901a\u8fc7\u6bd4\u8f83\u76ee\u6807\u533a\u57df\u5728\u6270\u52a8\u8f93\u5165\u4e0e\u57fa\u7ebf\u8f93\u5165\u4e0b\u8f93\u51fa\u7ed3\u679c\u7684\u5dee\u5f02\uff0c\u53ef\u4ee5\u63a8\u65ad\u4ece\u6e90\u533a\u57df\uff08\u88ab\u6270\u52a8\u533a\u57df\uff09\u5230\u76ee\u6807\u533a\u57df\u7684EC\u3002\u5982\u679c\u76ee\u6807\u533a\u57df\u6d3b\u52a8\u589e\u5f3a\uff0c\u5219\u8868\u793a\u5b58\u5728\u5174\u594b\u6027EC\uff1b\u82e5\u6d3b\u52a8\u51cf\u5f31\uff0c\u5219\u8868\u793a\u4e3a\u6291\u5236\u6027 EC<\/span>\uff08\u56fe 2h\uff09<\/span>\u3002\u901a\u8fc7\u5bf9\u6240\u6709\u8282\u70b9\u4f9d\u6b21\u65bd\u52a0\u6270\u52a8\uff0c\u6211\u4eec\u53ef\u4ee5\u523b\u753b\u5168\u8111\u4efb\u610f\u4e24\u4e2a\u8111\u533a\u4e4b\u95f4\u7684 EC \u8fde\u63a5<\/span>\uff08\u56fe 2d\uff09<\/span>\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n

\u6211\u4eec\u4f7f\u7528\u591a\u79cd\u5df2\u77e5\u771f\u5b9e EC \u7684\u751f\u6210\u6a21\u578b\u9a8c\u8bc1\u4e86 NPI \u6846\u67b6\u7684\u6709\u6548\u6027<\/span>\uff08\u56fe 2i\uff09<\/span>\u3002\u5f53\u5e94\u7528\u4e8e rs-fMRI \u6570\u636e\u65f6\uff0cNPI \u63ed\u793a\u4e86\u4eba\u8111 EC \u7684\u7279\u5f81<\/span>\uff08\u56fe 2j\uff09<\/span>\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u56fe2 | NPI \u901a\u8fc7\u865a\u62df\u6270\u52a8\u6570\u5b57\u5b6a\u751f\u8111\u63a8\u65ad EC<\/span><\/span><\/p>\n<\/section>\n


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\u5728\u751f\u6210\u6a21\u578b\u4e0a\u9a8c\u8bc1 NPI \u7684\u6709\u6548\u6027<\/span><\/span><\/span><\/p>\n


<\/span><\/span><\/p>\n

\u672c\u6587\u4f7f\u7528\u5df2\u77e5\u771f\u5b9e\u6709\u6548\u8fde\u63a5<\/span>\uff08ground-truth EC\uff09<\/span>\u7684\u751f\u6210\u6a21\u578b\u5bf9 NPI \u7684\u6027\u80fd\u8fdb\u884c\u4e86\u6d4b\u8bd5\u3002\u4f7f\u7528\u4e86\u4e09\u4e2a\u6a21\u62df\u6570\u636e\u96c6\uff1a\u4e00\u4e2a\u7531\u5faa\u73af\u795e\u7ecf\u7f51\u7edc<\/span>\uff08RNN\uff09<\/span>\u6a21\u578b\u751f\u6210<\/span>\uff08\u56fe 3a\u2013h\uff09<\/span>\uff0c\u53e6\u5916\u4e24\u4e2a\u6765\u81ea fMRI \u7684\u751f\u6210\u6a21\u578b<\/span>\uff08\u56fe 3i\u2013p\uff09<\/span>\u3002ground-truth EC \u662f\u901a\u8fc7\u5c06\u201c\u6270\u52a8-\u8bb0\u5f55\u201d\u8303\u5f0f\u76f4\u63a5\u5e94\u7528\u4e8e\u751f\u6210\u6a21\u578b\u4e0a\u83b7\u5f97\u7684\u3002\u6211\u4eec\u5c06 NPI \u63a8\u65ad\u7684 EC \u548c ground-truth EC \u8fdb\u884c\u6bd4\u8f83\u4ee5\u8bc4\u4f30\u5176\u6027\u80fd\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n

\u4ee5 RNN \u751f\u6210\u6a21\u578b\u4e3a\u4f8b\uff0c\u6211\u4eec\u6784\u5efa\u4e86\u4e00\u4e2a\u5177\u6709\u9884\u5b9a\u4e49\u8fde\u63a5\u7ed3\u6784\u7684 RNN \u6a21\u578b\uff0c\u5e76\u4f7f\u7528\u8be5\u6a21\u578b\u751f\u6210\u795e\u7ecf\u6d3b\u52a8\u6570\u636e<\/span>\uff08\u56fe 3a\u2013b\uff09<\/span>\u3002\u968f\u540e\uff0c\u6211\u4eec\u8bad\u7ec3 ANN \u4f5c\u4e3a\u6570\u5b57\u5b6a\u751f\u8111\uff0c\u4f7f\u5176\u5b66\u4e60 RNN \u751f\u6210\u6570\u636e\u7684\u52a8\u529b\u5b66\uff0c\u5e76\u901a\u8fc7\u9012\u5f52\u9884\u6d4b\u4ea7\u751f\u6a21\u62df\u795e\u7ecf\u4fe1\u53f7<\/span>\uff08\u56fe 3c\uff09<\/span>\u3002\u7531\u6b64\u751f\u6210\u7684 model FC \u4e0e empirical FC \u9ad8\u5ea6\u4e00\u81f4<\/span>\uff08\u56fe 3d\uff09<\/span>\uff0c\u9a8c\u8bc1\u4e86\u6a21\u578b\u7684\u5b66\u4e60\u80fd\u529b\u3002\u63a5\u7740\uff0c\u6211\u4eec\u5728 ANN \u4e0a\u7cfb\u7edf\u5730\u65bd\u52a0\u6270\u52a8\uff0c\u63a8\u65ad\u51fa\u8282\u70b9\u95f4\u7684 EC<\/span>\uff08\u56fe 3e\uff09<\/span>\u3002NPI \u63a8\u65ad\u7684 EC \u4e0e ground-truth EC<\/span>\uff08\u56fe 3f\uff09<\/span>\u4e4b\u95f4\u5177\u6709\u6781\u9ad8\u7684\u76f8\u5173\u6027\uff0c\u663e\u8457\u4f18\u4e8e\u683c\u5170\u6770\u56e0\u679c\u7b49\u4f20\u7edf\u65b9\u6cd5<\/span>\uff08\u56fe 3g\uff09<\/span>\u3002\u6b64\u5916\uff0c\u6211\u4eec\u8fd8\u8003\u5bdf\u4e86 NPI \u5728\u4e0d\u540c\u6761\u4ef6\u4e0b\u7684\u7a33\u5065\u6027\uff0c\u5305\u62ec\u6270\u52a8\u5f3a\u5ea6\u3001\u7cfb\u7edf\u566a\u58f0\u3001\u6570\u636e\u957f\u5ea6\u548c\u7f51\u7edc\u89c4\u6a21<\/span>\uff08\u56fe 3h\uff09<\/span>\u3002\u7ed3\u679c\u663e\u793a\uff0cNPI \u5728\u5927\u591a\u6570\u53c2\u6570\u8bbe\u7f6e\u4e0b\u90fd\u4fdd\u6301\u4e86\u7a33\u5b9a\u4e14\u51c6\u786e\u7684\u63a8\u65ad\u6027\u80fd\uff0c\u5c24\u5176\u662f\u5728\u6570\u636e\u91cf\u5145\u8db3\u7684\u60c5\u51b5\u4e0b\uff0c\u6269\u5c55\u5230\u66f4\u5927\u89c4\u6a21\u7684\u7f51\u7edc\u4e0a\u4e5f\u80fd\u7ef4\u6301\u826f\u597d\u7684\u8868\u73b0\u3002<\/span><\/span><\/p>\n


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\u4e3a\u8fdb\u4e00\u6b65\u8bc4\u4f30 NPI \u5728\u795e\u7ecf\u6570\u636e\u4e0a\u7684\u8868\u73b0\uff0c\u6211\u4eec\u5c06\u5176\u5e94\u7528\u4e8e\u4e24\u4e2a fMRI \u4eff\u771f\u6570\u636e\u96c6<\/span>\uff08\u56fe 3i\u2013p\uff09<\/span>\u3002\u7ed3\u679c\u663e\u793a\uff0c\u5373\u4f7f\u5728\u590d\u6742\u7684\u7f51\u7edc\u7ed3\u6784\u548c\u6a21\u62df fMRI \u52a8\u529b\u5b66\u7684\u6761\u4ef6\u4e0b\uff0cNPI \u4f9d\u7136\u80fd\u591f\u7a33\u5065\u5730\u8bc6\u522b\u51fa\u8282\u70b9\u95f4\u7684\u56e0\u679c\u5173\u7cfb\uff0c\u5177\u5907\u51fa\u8272\u7684\u51c6\u786e\u6027\u4e0e\u901a\u7528\u6027\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u56fe3 | \u5728\u771f\u5b9e\u6570\u636e\u4e0a\u9a8c\u8bc1 NPI \u7684\u6709\u6548\u6027<\/span><\/span><\/p>\n<\/section>\n


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NPI \u5f97\u5230\u7684\u4eba\u8111 EBC<\/span><\/span><\/span><\/p>\n


<\/span><\/span><\/p>\n

\u6211\u4eec\u5c06 NPI \u5e94\u7528\u5230 HCP \u6570\u636e\u96c6[2]\u4e2d 800 \u540d\u88ab\u8bd5\u7684 rs-fMRI \u6570\u636e\u4e0a\uff0c\u4e3a\u6bcf\u4f4d\u88ab\u8bd5\u5206\u522b\u8bad\u7ec3\u4e2a\u4f53\u5316\u7684 ANN\uff0c\u8111\u533a\u5212\u5206\u91c7\u7528 MMP \u8111\u56fe\u8c31[3]\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n

\u5728\u6bd4\u8f83\u4e0d\u540c\u7684\u8f93\u5165\u914d\u7f6e\u540e\uff0c\u6211\u4eec\u53d1\u73b0\u4f7f\u7528\u524d\u4e09\u4e2a\u65f6\u95f4\u6b65\u9884\u6d4b\u4e0b\u4e00\u4e2a\u65f6\u95f4\u6b65\u7684\u6a21\u578b\u4f18\u4e8e\u4ec5\u4f7f\u7528\u5355\u4e2a\u65f6\u95f4\u6b65\u7684\u6a21\u578b\uff0c\u4e14 model FC \u548c empirical FC \u9ad8\u5ea6\u76f8\u5173<\/span>\uff08\u56fe 4c-d\uff09<\/span>\u3002\u56e0\u6b64\uff0c\u6211\u4eec\u91c7\u7528\u4e09\u6b65\u8f93\u5165\u7684 MLP \u6a21\u578b\u4f5c\u4e3a\u540e\u7eed\u5206\u6790\u7684\u6807\u51c6\u7ed3\u6784\u3002\u6211\u4eec\u5206\u522b\u5bf9\u6bcf\u4f4d\u88ab\u8bd5\u7684\u4e2a\u4f53\u5316\u6570\u5b57\u5b6a\u751f\u8111\u8fdb\u884c\u6270\u52a8\u5206\u6790\uff0c\u968f\u540e\u5c06\u6240\u6709\u88ab\u8bd5\u7684\u4e2a\u4f53\u5316 EC \u5e73\u5747\uff0c\u5f97\u5230\u7fa4\u4f53\u6c34\u5e73\u7684\u4eba\u8111\u6709\u6548\u8fde\u63a5\u56fe\u8c31<\/span>\uff08effective brain connectome, EBC\uff09\uff08\u56fe 4a\uff09<\/span>\u3002EBC \u4e2d\u7684\u6b63\u503c\u4ee3\u8868\u5174\u594b\u6027\u8fde\u63a5\uff0c\u8d1f\u503c\u4ee3\u8868\u6291\u5236\u6027\u8fde\u63a5\u3002\u4e0e FC \u76f8\u6bd4\uff0cEC \u66f4\u597d\u5730\u6355\u6349\u4e86\u6e90\u533a\u57df\u5bf9\u5176\u4ed6\u533a\u57df\u7684\u6291\u5236\u6027\u8c03\u63a7\u4f5c\u7528<\/span>\uff08\u56fe 4e\uff09<\/span>\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n

\u901a\u8fc7\u5206\u6790 EBC\uff0c\u6211\u4eec\u53d1\u73b0\uff0c\u5174\u594b\u6027\u548c\u6291\u5236\u6027 EC \u7684\u5f3a\u5ea6\u5206\u522b\u670d\u4ece\u5bf9\u6570\u6b63\u6001\u5206\u5e03<\/span>\uff08\u56fe 4f-g\uff09<\/span>\u3002\u6700\u5f3a\u7684\u5174\u594b\u6027\u8fde\u63a5\u4e3b\u8981\u5206\u5e03\u5728\u529f\u80fd\u7f51\u7edc\u5185\u90e8\uff0c\u800c\u6700\u5f3a\u7684\u6291\u5236\u6027\u8fde\u63a5\u5219\u66f4\u591a\u51fa\u73b0\u5728\u8de8\u7f51\u7edc\u548c\u8de8\u534a\u7403\u4e4b\u95f4<\/span>\uff08\u56fe 4f-g\uff09<\/span>\u3002\u4e3a\u4e86\u5206\u6790\u6bcf\u4e2a\u8282\u70b9\u5728\u7f51\u7edc\u4e2d\u7684\u91cd\u8981\u7a0b\u5ea6\uff0c\u672c\u6587\u4e8c\u503c\u5316\u4e86 EBC \u77e9\u9635\u5e76\u8ba1\u7b97\u4e86\u6bcf\u4e2a\u8282\u70b9\u7684\u5ea6\uff0c\u53d1\u73b0\u4e0e\u5176\u4ed6\u533a\u57df\u8054\u7cfb\u7d27\u5bc6\u7684\u8111\u533a\u5e7f\u6cdb\u5206\u5e03\u4e8e\u591a\u4e2a\u529f\u80fd\u7f51\u7edc\uff0c\u663e\u793a\u51fa\u9ad8\u4e2d\u5fc3\u6027\u533a\u57df\u7684\u5e7f\u6cdb\u5206\u5e03<\/span>\uff08\u56fe 4h\uff09<\/span>\u3002<\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


<\/span><\/section>\n

<\/span><\/p>\n

\n

\u56fe4 | NPI\u9996\u6b21\u7ed8\u5236\u51fa\u4eba\u8111\u6709\u6548\u8fde\u63a5\u7ec4<\/span><\/span><\/p>\n<\/section>\n


<\/span><\/p>\n

\n
\n
\n
\n

NPI \u5f97\u5230\u7684 EC \u7a33\u5065\uff0c\u4e14\u53d7 SC \u652f\u6491<\/span><\/span><\/span><\/p>\n


<\/span><\/span><\/p>\n

\u4e3a\u4e86\u8bc4\u4f30 NPI \u5728 fMRI \u6570\u636e\u4e0a\u7684\u8868\u73b0\u4e0e\u8111\u533a\u6570\u7684\u5173\u7cfb\uff0c\u6211\u4eec\u5c06\u5176\u5e94\u7528\u4e8e\u4e0d\u540c\u5206\u8fa8\u7387\u7684 Schaefer \u8111\u56fe\u8c31[4]\uff0c\u8111\u533a\u6570\u91cf\u4ece 100 \u9010\u6b65\u589e\u52a0\u81f3 1000 \u4e2a<\/span>\uff08\u56fe 5a\u2013b\uff09<\/span>\u3002\u968f\u7740\u5206\u533a\u6570\u91cf\u589e\u52a0\uff0c\u9884\u6d4b\u6027\u80fd\u7565\u6709\u4e0b\u964d\uff0c\u8fd9\u53ef\u80fd\u662f\u7531\u4e8e\u66f4\u9ad8\u7684\u6570\u636e\u91cf\u8981\u6c42<\/span>\uff08\u56fe 3h\uff09<\/span>\u3002\u5c3d\u7ba1\u5982\u6b64\uff0c\u6a21\u578b\u5bf9 FC \u7684\u6062\u590d\u6548\u679c\u5728\u4e0d\u540c\u5c3a\u5ea6\u4e0b\u7a33\u5b9a<\/span>\uff08\u56fe 5b\uff09<\/span>\uff0c\u8bf4\u660e NPI \u6846\u67b6\u5728\u4e0d\u540c\u7c92\u5ea6\u4e0b\u5177\u6709\u4e00\u81f4\u7684\u8868\u73b0\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n

\u6b64\u5916\uff0c\u6211\u4eec\u8bc4\u4f30\u4e86 NPI \u6846\u67b6\u5728\u4e0d\u540c\u6761\u4ef6\u4e0b\u7684\u7a33\u5065\u6027\uff0c\u5305\u62ec\u4e0d\u540c ANN \u521d\u59cb\u5316\u65b9\u5f0f\u3001\u4e0d\u540c fMRI \u626b\u63cf\u65f6\u95f4\u6bb5\u3001\u4e0d\u540c\u88ab\u8bd5\u95f4\u3001\u4ee5\u53ca\u8de8\u6570\u636e\u96c6\u7684\u7ed3\u679c\u7684\u4e00\u81f4\u6027<\/span>\uff08\u56fe 5c\u2013e\uff09<\/span>\u3002\u7ed3\u679c\u663e\u793a\uff0cNPI \u5bf9 ANN \u521d\u59cb\u5316\u5177\u6709\u826f\u597d\u7684\u9c81\u68d2\u6027\uff0c\u80fd\u591f\u7a33\u5b9a\u5730\u63d0\u53d6\u4e2a\u4f53\u5316\u8fde\u63a5\u7279\u5f81\uff0c\u4e14\u7ed3\u679c\u53ef\u5728\u4e0d\u540c\u6570\u636e\u96c6\u4e0a\u91cd\u590d\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n

\u6211\u4eec\u8fd8\u7814\u7a76\u4e86 NPI \u63a8\u65ad\u7684 EBC \u4e0e SC \u4e4b\u95f4\u7684\u5173\u7cfb\u3002\u6211\u4eec\u4f7f\u7528 HCP \u6570\u636e\u96c6\u5f97\u5230\u7684 SC \u4e0e NPI \u63a8\u65ad\u7684 EBC \u8fdb\u884c\u5bf9\u6bd4\u3002\u5206\u6790\u53d1\u73b0\uff0c\u4e24\u8005\u4e4b\u95f4\u5b58\u5728\u663e\u8457\u76f8\u5173\u6027<\/span>\uff08\u56fe 5f\uff09<\/span>\uff0c\u8fdb\u4e00\u6b65\u8868\u660e\u5927\u8111\u89e3\u5256\u7ed3\u6784\u5728\u529f\u80fd\u901a\u4fe1\u4e2d\u7684\u91cd\u8981\u4f5c\u7528\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\n
<\/section>\n<\/section>\n
\n

\u56fe5 | NPI \u5f97\u5230\u7684 EC \u7a33\u5065\uff0c\u4e14\u53d7 SC \u652f\u6491<\/span><\/span><\/p>\n<\/section>\n


<\/span><\/p>\n

\n
\n
\n
\n

NPI \u6846\u67b6\u53ef\u652f\u6491\u4e34\u5e8a\u5e94\u7528<\/span><\/span><\/span><\/p>\n


<\/span><\/span><\/p>\n

\u4e3a\u8bc4\u4f30 NPI \u7684\u4e34\u5e8a\u4ef7\u503c\uff0c\u6211\u4eec\u4f7f\u7528 F-TRACT \u9879\u76ee[5]\u63d0\u4f9b\u7684 CCEP \u6570\u636e\u8fdb\u884c\u9a8c\u8bc1\u3002\u8be5\u6570\u636e\u96c6\u57fa\u4e8e\u766b\u75eb\u60a3\u8005\u7684\u7acb\u4f53\u8111\u7535\u56fe<\/span>\uff08SEEG\uff09<\/span>\u8bb0\u5f55<\/span>\uff08\u56fe 6b\uff09<\/span>\u6784\u5efa\u4e86\u7fa4\u4f53\u6c34\u5e73\u7684 CCEP \u8fde\u63a5\u77e9\u9635<\/span>\uff08\u56fe 6a\uff09<\/span>\u3002\u8be5\u77e9\u9635\u53cd\u6620\u4e86\u795e\u7ecf\u4fe1\u53f7\u5728\u76ae\u5c42\u95f4\u7684\u4f20\u64ad\u8def\u5f84\uff0c\u662f\u7528\u4e8e\u9a8c\u8bc1 NPI \u63a8\u65ad\u7684 EBC \u7684\u7406\u60f3\u53c2\u8003\u6807\u51c6\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n

\u6211\u4eec\u5c06\u57fa\u4e8e HCP \u6570\u636e\u96c6\u5f97\u5230\u7684\u7fa4\u4f53\u5e73\u5747 EBC \u4e0e CCEP \u8fde\u63a5\u77e9\u9635\u8fdb\u884c\u6bd4\u8f83\uff0c\u53d1\u73b0\u4e24\u8005\u5728\u5168\u8111\u6c34\u5e73\u4e0a\u7684\u76f8\u5173\u6027\u663e\u8457\u9ad8\u4e8e FC \u4e0e CCEP \u7684\u76f8\u5173\u6027\u3002\u8fd9\u8868\u660e\uff0cNPI \u63a8\u65ad\u5f97\u5230\u7684 EBC \u80fd\u51c6\u786e\u53cd\u6620\u795e\u7ecf\u523a\u6fc0\u540e\u7684\u4fe1\u53f7\u4f20\u64ad\u8def\u5f84\uff0c\u63ed\u793a\u6f5c\u5728\u7684\u56e0\u679c\u7ed3\u6784\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n

\u4e3a\u4e86\u8fdb\u4e00\u6b65\u5c55\u793a EBC \u5728\u6307\u5bfc\u795e\u7ecf\u523a\u6fc0\u4e2d\u7684\u6f5c\u529b\uff0c\u6211\u4eec\u6bd4\u8f83\u4e86 CCEP \u4e0e NPI \u63a8\u65ad\u7684\u8f93\u51fa\u8fde\u63a5<\/span>\uff08output EC\uff09<\/span>\u548c\u8f93\u5165\u8fde\u63a5<\/span>\uff08input EC\uff09<\/span>\u4e4b\u95f4\u7684\u5173\u7cfb\u3002\u5728 EBC \u77e9\u9635\u4e2d\uff0c\u4e00\u884c\u4ee3\u8868\u67d0\u4e00\u533a\u57df\u5bf9\u6240\u6709\u5176\u4ed6\u533a\u57df\u7684\u8f93\u51fa\uff0c\u5373 output EC\uff1b\u4e00\u5217\u4ee3\u8868\u5176\u4ed6\u533a\u57df\u5bf9\u67d0\u4e00\u76ee\u6807\u533a\u57df\u7684\u8f93\u5165\uff0c\u5373 input EC<\/span>\uff08\u56fe 6e\uff09<\/span>\u3002\u7ed3\u679c\u8868\u660e\uff0c\u65e0\u8bba\u662f input EC \u8fd8\u662f output EC\uff0cNPI \u63a8\u65ad\u7684\u7ed3\u679c\u90fd\u4e0e CCEP \u7684\u7a7a\u95f4\u6a21\u5f0f\u9ad8\u5ea6\u4e00\u81f4\uff0c\u663e\u8457\u4f18\u4e8e FC<\/span>\uff08\u56fe 6f\u2013g\uff09<\/span>\u3002\u8fd9\u4e9b\u7ed3\u679c\u8fdb\u4e00\u6b65\u652f\u6301\u4e86 NPI \u80fd\u591f\u7cbe\u786e\u6355\u6349\u7279\u5b9a\u533a\u57df\u95f4\u7684\u56e0\u679c\u4f20\u64ad\u8def\u5f84\u7684\u7ed3\u8bba\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n

\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0cNPI \u76f8\u8f83\u4e8e CCEP \u8fd8\u5177\u5907\u989d\u5916\u4f18\u52bf\u3002CCEP \u8981\u6c42\u5bf9\u60a3\u8005\u8fdb\u884c\u4fb5\u5165\u5f0f\u7535\u523a\u6fc0\u548c\u6570\u636e\u91c7\u96c6\uff0c\u6bcf\u4f4d\u60a3\u8005\u53ea\u80fd\u63d0\u4f9b\u5c11\u91cf\u523a\u6fc0\u548c\u8bb0\u5f55\u4f4d\u70b9\u7684\u6570\u636e\uff0c\u56e0\u6b64\u5fc5\u987b\u8de8\u4e2a\u4f53\u6574\u5408\u624d\u80fd\u6784\u5efa\u5168\u8111\u7684\u8fde\u63a5\u56fe\u8c31\u3002\u800c NPI \u5b8c\u5168\u57fa\u4e8e\u975e\u4fb5\u5165\u7684 rs-fMRI \u6570\u636e\u5efa\u6a21\uff0c\u5177\u6709\u66f4\u5f3a\u7684\u901a\u7528\u6027\u4e0e\u53ef\u63a8\u5e7f\u6027\u3002\u56e0\u6b64\uff0cNPI \u5728\u7814\u7a76\u548c\u4e34\u5e8a\u5e94\u7528\u4e2d\u66f4\u52a0\u7075\u6d3b\u4fbf\u6377\uff0c\u6f5c\u529b\u5de8\u5927\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\n
<\/section>\n<\/section>\n
\n

\u56fe6 | \u4f7f\u7528 CCEP \u9a8c\u8bc1 NPI \u6846\u67b6\u5f97\u5230\u7684 EC<\/span><\/span><\/p>\n<\/section>\n


<\/span><\/p>\n

\n
\n
\n


<\/span><\/span><\/p>\n

\n
\n
\n
\n
\n

<\/span><\/section>\n

<\/span><\/section>\n
\n
<\/section>\n<\/section>\n<\/section>\n
\n

3. NCClab \u7684\u8ba8\u8bba<\/span><\/strong><\/span><\/strong><\/strong><\/p>\n<\/section>\n

\n

<\/span><\/section>\n

<\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/h3>\n


<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n
\n

\u672c\u6587\u63d0\u51fa\u7684 NPI \u6846\u67b6\u901a\u8fc7\u6a21\u62df\u201c\u6270\u52a8-\u8bb0\u5f55\u201d\u8303\u5f0f\u4e3a\u975e\u4fb5\u5165\u5730\u63a8\u65ad\u5168\u8111 EC \u63d0\u4f9b\u4e86\u4e00\u79cd\u65b0\u8def\u5f84\u3002\u76f8\u8f83\u4e8e FC\uff0cNPI \u523b\u753b\u7684 EC \u5177\u6709\u56e0\u679c\u610f\u4e49\uff0c\u80fd\u591f\u53cd\u6620\u8111\u533a\u4e4b\u95f4\u7684\u4fe1\u606f\u4f20\u9012\u65b9\u5411\u53ca\u8c03\u63a7\u5173\u7cfb\uff1b\u540c\u65f6\uff0c\u76f8\u6bd4\u5df2\u6709\u7684EC\u8ba1\u7b97\u65b9\u6cd5\uff0cNPI \u5177\u5907\u66f4\u5f3a\u7684\u7075\u6d3b\u6027\u4e0e\u6cdb\u5316\u80fd\u529b\uff0c\u80fd\u591f\u5728\u65e0\u9700\u5047\u8bbe\u795e\u7ecf\u7cfb\u7edf\u7ed3\u6784\u7684\u524d\u63d0\u4e0b\uff0c\u4ec5\u4f9d\u8d56 rs-fMRI \u6570\u636e\u63a8\u65ad\u51fa\u5168\u8111\u56e0\u679c\u56fe\u8c31\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n

NPI\u63d0\u51fa\u8bad\u7ec3AI\u6a21\u578b\u81ea\u76d1\u7763\u5b66\u4e60\u8111\u7f51\u7edc\u52a8\u529b\u5b66\uff0c\u5c06\u8bad\u7ec3\u7684AI\u4f5c\u4e3a\u201c\u66ff\u4ee3\u5927\u8111\u201d\uff0c\u5728AI\u6a21\u578b\u4e2d\u8fdb\u884c\u865a\u62df\u6270\u52a8\uff0c\u5e76\u8bb0\u5f55\u6270\u52a8\u5bf9\u5176\u4ed6\u8111\u533a\u7684\u5f71\u54cd\uff0c\u4ece\u800c\u6784\u5efa\u51fa\u5177\u6709\u751f\u7406\u53ef\u89e3\u91ca\u6027\u7684\u56e0\u679c\u5173\u7cfb\u3002\u6211\u4eec\u5728\u6a21\u62df\u6570\u636e\u3001rs-fMRI \u6570\u636e\u4e2d\u5747\u9a8c\u8bc1\u4e86 NPI \u7684\u6709\u6548\u6027\uff0c\u5f3a\u8c03\u4e86\u8be5\u65b9\u6cd5\u7684\u4e34\u5e8a\u6f5c\u529b\u3002<\/span><\/span><\/p>\n


<\/span><\/p>\n

NPI\u6846\u67b6\u4ecd\u5b58\u5728\u82e5\u5e72\u5f85\u5b8c\u5584\u4e4b\u5904\u3002\u9996\u5148\uff0cNPI\u662f\u4e00\u79cd\u6570\u636e\u9a71\u52a8\u7684\u65b9\u6cd5\uff0c\u4f9d\u8d56\u4e8e\u6570\u636e\u7684\u8d28\u91cf\u548csize\uff0c\u5728\u65f6\u5e8f\u957f\u5ea6\u6709\u9650\u3001\u8111\u533a\u7ef4\u5ea6\u8fc7\u9ad8\u3001\u4fe1\u53f7\u8d28\u91cf\u4e0d\u4f73\u7684\u60c5\u5883\u4e0b\uff0c\u5176\u5efa\u6a21\u4e0e\u63a8\u65ad\u80fd\u529b\u4ecd\u9700\u52a0\u5f3a\u3002\u5176\u6b21\uff0cNPI\u65b9\u6cd5\u76ee\u524d\u4e3b\u8981\u5728 rs-fMRI \u6570\u636e\u4e2d\u9a8c\u8bc1\uff0c\u672a\u6765\u9700\u8981\u8fdb\u4e00\u6b65\u5c06AI\u5b6a\u751f\u8111\u7684\u5efa\u6a21\u65b9\u6cd5\u6269\u5c55\u81f3\u4efb\u52a1\u6001\u6570\u636e\u3001EEGMEG\u7b49\u5176\u4ed6\u6a21\u6001\u7684\u795e\u7ecf\u6570\u636e\u3001\u4ee5\u53caSEEG\u8fd9\u7c7b\u7a00\u758f\u89c2\u6d4b\u7684\u6570\u636e\u4e2d\uff0c\u8fd9\u9700\u8981\u66f4\u591a\u7684AI\u6a21\u578b\u7ed3\u6784\u8bbe\u8ba1\u3001\u635f\u5931\u51fd\u6570\u548c\u8bad\u7ec3\u65b9\u6cd5\u7684\u8bbe\u8ba1\u3002<\/span><\/span><\/p>\n


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\u672a\u6765\u7684\u7814\u7a76\u65b9\u5411\u6709\u5e7f\u6cdb\u7684\u6269\u5c55\u7a7a\u95f4\uff1a\u5176\u4e00\uff0c\u901a\u8fc7\u5f15\u5165\u7ed3\u6784\u8fde\u63a5\u3001\u884c\u4e3a\u8868\u578b\u7b49\u5916\u90e8\u5148\u9a8c\uff0c\u6784\u5efa\u591a\u6a21\u6001\u6570\u636e\u878d\u5408\u7684 NPI \u6846\u67b6\uff0c\u63d0\u5347\u6a21\u578b\u5bf9 EC \u7684\u63a8\u65ad\u80fd\u529b\uff1b\u5176\u4e8c\uff0c\u5728\u7fa4\u4f53\u9884\u8bad\u7ec3\u6a21\u578b\u7684\u57fa\u7840\u4e0a\u5f15\u5165\u4e2a\u4f53\u5fae\u8c03\u7b56\u7565\uff0c\u5728\u77ed\u6570\u636e\u4e0a\u5b9e\u73b0\u7cbe\u51c6\u7684\u4e2a\u4f53\u5316 EC \u63a8\u65ad\uff1b\u5176\u4e09\uff0c\u62d3\u5c55\u6270\u52a8\u8bbe\u8ba1\u4e0e\u6a21\u62df\u65b9\u5f0f\uff0c\u4f7f NPI \u652f\u6301\u4e0d\u540c\u5f3a\u5ea6\u3001\u6301\u7eed\u65f6\u95f4\u6216\u591a\u70b9\u8054\u5408\u6270\u52a8\uff0c\u4ece\u800c\u670d\u52a1\u4e8e\u95ed\u73af\u795e\u7ecf\u8c03\u63a7\u7b49\u66f4\u5177\u6311\u6218\u6027\u7684\u5e94\u7528\u573a\u666f\u3002<\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

NPI\u7684\u4ee3\u7801\u5f00\u6e90\uff1a<\/span><\/span>github.com\/ncclab-sustech\/NPI<\/span><\/span><\/span><\/section>\n
\u539f\u6587\u94fe\u63a5\uff1ahttp:\/\/www.nature.com\/articles\/s41592-025-02654-x<\/span><\/span><\/span><\/section>\n

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\u8d2d\u4e70\u94fe\u63a5\uff1a<\/span><\/span>\u4f5c\u8005\u76ee\u524d\u5f00\u542f\u5feb\u56e2\u56e2\u901a\u9053\uff0c\u8d2d\u4e70\u8005\u53ef\u83b7\u53d6To\u7b7e\u7248\u672c\uff0c\u8bb0\u5f97\u5728\u5907\u6ce8\u586b\u5199\u201c\u540d\u5b57+\u5e0c\u671b\u6536\u5230\u7684\u8bdd\u201d\uff0870\u5143\/\u672c\uff0c\u5305\u90ae\u7b7e\u540d\u7248\uff09\u3002<\/span><\/span><\/span><\/section>\n

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[1] Park, Hae-Jeong, and Karl Friston. "Structural and functional brain networks: from connections to cognition." Science 342.6158 (2013): 1238411.<\/span><\/span><\/span><\/p>\n

[2] Van Essen, David C., et al. "The WU-Minn human connectome project: an overview." NeuroImage 80 (2013): 62-79.<\/span><\/span><\/p>\n

[3] Glasser, Matthew F., et al. "A multi-modal parcellation of human cerebral cortex." Nature 536.7615 (2016): 171-178.<\/span><\/span><\/p>\n

[4] Schaefer, Alexander, et al. "Local-global parcellation of the human cerebral cortex from intrinsic functional connectivity MRI." Cerebral cortex 28.9 (2018): 3095-3114.<\/span><\/span><\/p>\n

[5] Lemar\u00e9chal, Jean-Didier, et al. "A brain atlas of axonal and synaptic delays based on modelling of cortico-cortical evoked potentials." Brain 145.5 (2022): 1653-1667.<\/span><\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u8ba1\u7b97\u795e\u7ecf\u79d1\u5b66\u7b2c\u4e09\u5b63\u8bfb\u4e66\u4f1a<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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\u7ee7\u300c\u795e\u7ecf\u52a8\u529b\u5b66\u6a21\u578b<\/a>\u300d\u4e0e\u300c\u8ba1\u7b97\u795e\u7ecf\u79d1\u5b66<\/a>\u300d\u8bfb\u4e66\u4f1a\u540e\uff0c\u96c6\u667a\u4ff1\u4e50\u90e8\u8054\u5408\u6765\u81ea\u6570\u5b66\u3001\u7269\u7406\u5b66\u3001\u751f\u7269\u5b66\u3001\u795e\u7ecf\u79d1\u5b66\u548c\u8ba1\u7b97\u673a\u7684\u4e00\u7ebf\u7814\u7a76\u8005\u5171\u540c\u53d1\u8d77\u300c\u4ece\u795e\u7ecf\u52a8\u529b\u5b66\u5230\u610f\u8bc6\uff1a\u8de8\u5c3a\u5ea6\u8ba1\u7b97\u3001\u6f14\u5316\u4e0e\u6d8c\u73b0\u300d\u8bfb\u4e66\u4f1a<\/a>\uff0c\u8de8\u8d8a\u5fae\u89c2\u3001\u4ecb\u89c2\u4e0e\u5b8f\u89c2\u7684\u89c6\u89d2\uff0c\u63a2\u7d22\u610f\u8bc6\u4e0e\u667a\u80fd\u7684\u8de8\u5c3a\u5ea6\u8ba1\u7b97\u3001\u6f14\u5316\u4e0e\u6d8c\u73b0\u3002\u91cd\u70b9\u63a2\u8ba8\u7269\u7406\u89c4\u5f8b\u4e0e\u4eba\u5de5\u667a\u80fd\u5982\u4f55\u5e2e\u52a9\u6211\u4eec\u8ba4\u8bc6\u795e\u7ecf\u52a8\u529b\u5b66\uff0c\u4ee5\u53ca\u795e\u7ecf\u6d3b\u52a8\u8de8\u5c3a\u5ea6\u7684\u8ba1\u7b97\u4e0e\u6f14\u5316\u5982\u4f55\u6784\u5efa\u5fae\u89c2\u4e0e\u5b8f\u89c2\u3001\u7ed3\u6784\u4e0e\u529f\u80fd\u4e4b\u95f4\u7684\u6865\u6881\u3002<\/span><\/p>\n

\"\u56fe\u7247\"<\/section>\n
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1. \u8111\u7f51\u7edc\u4e2d\u7684\u56e0\u679c\u6d8c\u73b0\u7406\u8bba\u5e94\u7528\uff1a\u6765\u81ea\u4fe1\u606f\u5206\u89e3\u7684\u542f\u793a<\/span><\/a><\/span><\/strong>
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2. Nat. Comput. Sci.\u901f\u9012\uff1a\u5927\u8111\u663e\u8457\u6027\u7f51\u7edc\u6291\u5236\u9ed8\u8ba4\u6a21\u5f0f\u7f51\u7edc\u7684\u56e0\u679c\u673a\u5236<\/span><\/a><\/span><\/strong>
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3. \u8111\u542f\u53d1\u5b66\u4e60\u7efc\u8ff0\uff1a\u4eba\u5de5\u795e\u7ecf\u7f51\u7edc\u7684\u4e0b\u4e00\u573a\u9769\u547d\uff1f<\/span><\/a><\/span><\/strong><\/section>\n
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4. <\/span>\u6d8c\u73b0\u52a8\u529b\u5b66\u5982\u4f55\u7528\u6765\u5206\u6790\u590d\u6742\u7cfb\u7edf\uff1f | \u65b0\u8bfe\u4e0a\u7ebf<\/span><\/a><\/span><\/strong><\/span>
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6. \u9ad8\u8003\u5206\u6570\u53ea\u662f\u5f20\u5165\u573a\u5238\uff0c\u4f60\u7684\u79d1\u7814\u5192\u9669\u5728\u8fd9\u91cc\u542f\u822a\uff01<\/span><\/a><\/span><\/strong><\/p>\n

7.<\/span><\/span><\/strong><\/strong><\/span>\u91cd\u6574\u5316\u7fa4\u4e0e\u975e\u7ebf\u6027\u7269\u7406\uff0c\u5bfb\u627e\u590d\u6742\u7cfb\u7edf\u8de8\u5c3a\u5ea6\u7684\u5206\u6790\u65b9\u6cd5\u4e28\u65b0\u8bfe\u53d1\u5e03<\/a><\/span><\/strong><\/strong><\/span><\/p>\n


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\u70b9\u51fb\u201c\u9605\u8bfb\u539f\u6587\u201d\uff0c\u62a5\u540d\u8bfb\u4e66\u4f1a<\/span><\/span><\/section>\n<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u5bfc\u8bed \u5927\u8111\u662f\u4e00\u4e2a\u7531\u591a\u4e2a\u76f8\u4e92\u8fde\u63a5\u7684\u8111\u533a\u7ec4\u6210\u7684\u590d\u6742\u7f51\u7edc\uff0c\u7406\u89e3\u8fd9\u4e9b\u8111\u533a\u4e4b\u95f4\u4fe1\u606f\u5982\u4f55\u6d41\u52a8\uff0c\u662f\u63ed\u793a\u5927\u8111\u5de5\u4f5c\u673a\u5236\u7684\u6838\u5fc3\u95ee\u9898\u4e4b\u4e00\u3002\u4f20\u7edf\u7684\u7ed3\u6784\u8fde\u63a5\uff08SC\uff09\u548c\u529f\u80fd\u8fde\u63a5\uff08FC\uff09\u96be\u4ee5\u63ed\u793a\u4fe1\u606f\u5728\u5927\u8111\u4e2d\u7684\u65b9\u5411\u6027\u4f20\u9012\u4e0e\u56e0\u679c\u7ed3\u6784\u3002\u6709\u6548\u8fde\u63a5\uff08EC\uff09\u5219\u901a\u8fc7\u6355\u6349\u8111\u533a\u4e4b\u95f4\u7684\u56e0\u679c\u4ea4\u4e92\uff0c\u5f25\u8865\u4e86\u8fd9\u4e00\u5173\u952e\u7a7a\u767d\u4f46\u5f80\u5f80\u4f9d\u8d56\u4fb5\u5165\u5f0f\u64cd\u4f5c\uff0c\u4e14\u96be\u4ee5\u6269\u5c55\u5230\u5168…<\/p>\n","protected":false},"author":0,"featured_media":64647,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"special":[],"_links":{"self":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/64664"}],"collection":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=64664"}],"version-history":[{"count":0,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/posts\/64664\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=\/wp\/v2\/media\/64647"}],"wp:attachment":[{"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=64664"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=64664"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=64664"},{"taxonomy":"special","embeddable":true,"href":"https:\/\/swarma.org\/index.php?rest_route=%2Fwp%2Fv2%2Fspecial&post=64664"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}